Aligned Health Ventures

Investment thesis

Aligned Health Ventures is a seed-stage firm backing AI-enabled companies working on the clinical conditions that carry the highest burden and cost in American healthcare. We invest across five verticals: cardiometabolic disease, behavioral health, maternal and pediatric health, oncology and specialty care, and the infrastructure and platform layers these depend on. Burden alone is not enough. We invest where failing to solve the problem is already expensive for a specific economic buyer, because that is what turns a clinical need into a purchase decision. And we invest at seed, where a company's clinical assumptions and evidence strategy are still being set. Every portfolio company receives BoardKit at investment, governance infrastructure that creates institutionally auditable board practice from the first check. Based in the Nashville area. Mission-first discipline. Market-rate returns.