Jon Root
InvestorGeneral Partner at US Venture Partners · General Partner, US Venture Partners (Investment Advisory Committee) at Mission Bay Capital · Board director at Surgical Safety Technologies · Board director at Carlsmed · Board director at Edgewise Therapeutics
Menlo Park, California
Writes $2M – $10M checks · typically $6M
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About
A board-certified neurologist and physician, Jon Root evaluates medical and biotech investments with a clinical practitioner's perspective. He joined USVP in 1995 as a Kauffman Fellow and became a general partner in 1997, previously serving on the faculty at The New York Hospital-Cornell Medical Center.
Contact· self-published, not guessed
Invests in
BiotechDigital HealthHealthtechMedical Devices
Board director at Surgical Safety Technologies
Intro paths
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Surgical Safety Technologies's investors · 2
Co-founders at Surgical Safety Technologies
Board director at Carlsmed
Intro paths
In turn, Jon can intro founders to Carlsmed's investors below.
Carlsmed's investors · 8
Co-founders at Carlsmed


Board director at Edgewise Therapeutics
Intro paths
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Edgewise Therapeutics's investors · 8
Co-founders at Edgewise Therapeutics


Experience
- U.S. Venture PartnersGeneral Partner
Deals · 1
Surgical Safety TechnologiesBoard seat
via US Venture Partners · filed Mar 2026 · $20.2M raise
Attribution from SEC filings, press coverage, and firm rosters.
Other disclosed investments
Board seats
CarlsmedCarrot FertilityContego MedicalEdgewise TherapeuticsHealthjoyInari MedicalNervonikOkami MedicalOmada HealthRoute 92 MedicalSparrow PharmaceuticalsVI1VS3 Medical
Investor
AimbientAltus PharmaceuticalsArticulinxCanDoCarlsmedCastlight Health IncEdgewise TherapeuticsEffector TherapeuticsHealthjoyIlypsaInari MedicalNervonikOkami MedicalOmada HealthOncoMed PharmaceuticalsRoute 92 MedicalSilverback TherapeuticsSparrow PharmaSwoop
Sources: the firm's website · SEC Form D filings · curated public sources.
Colleagues at US Venture Partners
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Investors connected to Jon in public investor directories — a warm-intro map.
Frequently asked questions
- Who is Jon Root?
- A board-certified neurologist and physician, Jon Root evaluates medical and biotech investments with a clinical practitioner's perspective. He joined USVP in 1995 as a Kauffman Fellow and became a general partner in 1997, previously serving on the faculty at The New York Hospital-Cornell Medical Center.
- Where does Jon Root work?
- Jon Root is General Partner at US Venture Partners and Board director at Surgical Safety Technologies and Board director at Carlsmed and Board director at Edgewise Therapeutics.
- What does Jon Root invest in?
- Jon Root invests in Biotech, Digital Health, Healthtech, Medical Devices.
- What check size does Jon Root write?
- Jon Root typically writes checks of $2M – $10M.
- What boards does Jon Root sit on?
- Jon Root holds tracked board seats at Carlsmed, Carrot Fertility, Contego Medical, Edgewise Therapeutics, Healthjoy, Inari Medical, Nervonik, Okami Medical, Omada Health, Route 92 Medical.
- What companies has Jon Root invested in?
- Investments tracked here include Aimbient, Altus Pharmaceuticals, Articulinx, CanDo, Carlsmed, Castlight Health Inc, Edgewise Therapeutics, Effector Therapeutics, Healthjoy, Ilypsa, Inari Medical, Nervonik, and 7 more.
Shared employers
Also worked at U.S. Venture Partners24
+ 18 more



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