Blue Bear Ventures
Venture capitalSan Francisco · Pre-Seed–Series A · 6 people tracked
Investment thesis
Co-founder-focused fund for lab-based teams at the health–climate intersection (gene therapy, synthetic biology, batteries), offering deep access to UC Berkeley, UCSF, MIT and Stanford research and scientist-founders.
Source: firm website, verified Aug 7, 2026.
Team · 6 people
from the firm's website & public directories
What they invest in
from 19 of 27 portfolio companiesBiotech ×10AI & Machine Learning ×6Deep Tech ×6Healthtech ×6Medical Devices ×6Energy ×3Hardware ×3Cleantech ×2
HQs:United States×12
Investments · 27 tracked
founders shown can be your intro pathBy year:2023 · 12022 · 12019 · 13 dated
Aether (Aether Biomachines) is an AI company that uses a Protein Function Model and a robotic high-throughput screening lab to discover novel proteins and materials for industrial manufacturing, including reinforced nylon 3D-printing filaments and proteins for critical minerals processing.
AI & Machine LearningBiotechNew Materials
Co-investors4DX VenturesAbstract VenturesArtis VenturesBoxGroupCalm VenturesEvolution VC Partners+7 more
Aluna develops a portable respiratory management tool for children with asthma and other chronic respiratory diseases.
Digital HealthHealthtechMedical Devices
Charvi Shetty(Chief Executive Officer)inInderjit Jutla(Chief Scientific Officer)
Co-investorsGood Growth CapitalMatrixRho Capital PartnersRho VenturesZühlke Ventures
Ayar Labs develops co-packaged optics (CPO) technology for AI infrastructure, enabling optical connectivity between thousands of GPUs across data center racks.
AI & Machine LearningDeep TechHardwareSemiconductorsSan Jose, US
Mark Wade(Founder & CEO)in
Co-investorsAlumni VenturesBasecamp FundBerkeley FrontierCastor Ventures (an Alumni Ventures Fund)Factorial FundsG Vision Capital+14 more
BioAmp Diagnostics develops a chemistry-based rapid diagnostic pipeline (DETECT: Dual-Enzyme Trigger-Enabled Cascade Technology) that delivers infection results in minutes to guide antibiotic prescribing, initially targeting complicated urinary tract infections.
BiotechDigital HealthMedical DevicesSan Carlos, US
Tara DeBoer(Chief Executive Officer)inAngel Resendez(Director of Chemistry - Small Molecule Discovery, CSIO)in
BreezeBio develops a programmable delivery platform called NanoGalaxy for targeted delivery of genetic medicines to specific cells and tissues.
BiotechDeep TechMedical Devices
Co-investorsIMM Investment JapanDCVC (Data Collective)
Clarity provides air quality monitoring covering ambient pollutants such as particulate matter, ozone, nitrogen dioxide, carbon monoxide, and sulfur dioxide.
Climate TechHardwareIoT
Co-investorsKickstart VenturesSoundproof VenturesSpero Ventures
Coreshell develops silicon-based battery materials using metallurgical silicon, an unprocessed natural form of silicon, as a lower-cost anode material for EV batteries.
CleantechEnergyNew Materials
Co-investorsBaruch Future VenturesEntrada VenturesFoothill VenturesHelios Climate VenturesTrousdale Ventures
Correlia Bio develops the PIXI platform, a benchtop automated immunoassay system that uses proprietary microfluidic gel technology to quantify proteins from samples as small as 1 uL.
BiotechDeep TechHardwareHealthtechMedical DevicesSan Francisco, US
Akwasi Apori(Founder)inKursad Araz(Founder/CTO)inSamuel Tia(Founder)in
Co-investorsBeresford VenturesCota CapitalPallasite VenturesPangaea Ventures Us Inc.Y Combinator
Co-investorsBetter Ventures Central LlcSafar PartnersKdT Ventures
Particella, Inc. (formerly DNAlite Therapeutics) is a preclinical biotechnology company developing an oral lipid nanoparticle platform to deliver nucleic acids, such as mRNA, to the intestinal epithelium.
BiotechDeep TechSan Francisco, US
Mubhij Ahmad(Executive Officer, Director)David Rabuka(Director)Timothy Paul Day(Director)
BoardAndrew Cain McClary(Director)Drew Lanza(Director)
Co-investorsBerkeley CatalystKdT Ventures
Transforming delivery of gene therapies for non-viral, gene editing-based therapeutics.
Co-investorsAxial VC
ImpriMedicine provides live-cell-based predictive analytics to identify effective drugs for treating blood cancers in dogs and cats, offering patient-specific drug response predictions.
AI & Machine LearningBiotechHealthtech
Co-investorsDFJ DragonFundHan River Partners
Lockheed Martin is a defense and aerospace company that develops military aircraft and advanced technology systems for government and defense customers.
Deep TechDefense TechSpace Tech
New Sun Road builds Stellar, a microgrid energy management platform combining Microgrid OS and Edge hardware that uses IoT data and AI to monitor, control, and optimize power systems such as solar and battery installations.
CleantechEnergyIoTRichmond, US
Jalel Sager(Director)inAustin Cappon(Director)inCandice Eggerss(Director)Adrienne Pierce(Executive Officer, Director)inChad Riley(Director)
BoardAndrew Karetsky(Director)
Co-investorsSkyview Ventures
Numericcal provides machine learning software for detecting anomalies, tracking assets, and managing workforce activities in automotive and manufacturing facilities, processing video and audio data across on-premises and cloud infrastructure to reduce operating costs.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareSan Francisco, US
Shaoyi Cheng(Founder)inranko sredojevic(Founder)in
Co-investorsY Combinator
BCG is a strategy consulting firm that advises clients on business transformation, artificial intelligence implementation, and organizational performance.
AI & Machine LearningEnterprise SoftwareBoston, US
Co-investors2050FirstCheck AfricaSavia Ventures
Building new drugs to target inflammation using an AI + immunology discovery engine.
BiotechHealthtechSan Francisco, US
Jason Barbour(Founder/CEO)inDavid Ott(Founder/CTO)in
Co-investorsY Combinator
Unnatural Products is a drug discovery platform company that develops synthetic macrocycles to target previously undruggable disease targets.
AI & Machine LearningBiotechDeep TechMedical DevicesSanta Cruz, US
Cameron Pye(Co-Founder & CEO)Joshua Schwochert(Co-Founder & CSO)
BoardVasudev Bailey(Director)in
Co-investorsAbstract VenturesArtis VenturesAsset Management CompanyBetter Ventures Central LlcDroia VenturesFirst Spark Ventures, Llc+6 more
YourChoice Therapeutics is developing YCT-529, a non-hormonal oral contraceptive for men currently in Phase 2 clinical trials.
BiotechFemTechHealthtech
Akash Bakshi, MSc(Co-founder & CEO)Nadja Mannowetz, PhD(Co-founder & CSO)
Co-investorsCivilization Ventures Management, LlcForeground CapitalFuture VenturesNorth South VenturesPortfoliaOlive Tree Capital+1 more
YourChoice Therapeutics develops YCT-529, a non-hormonal oral contraceptive for men currently in Phase 2 clinical trials that works by blocking a receptor essential for sperm production.
BiotechHealthtechMedical DevicesSan Francisco, US
Akash Bakshi(Founder)inNadja Mannowetz(Founder)in
Co-investorsForeground CapitalOlive Tree CapitalPortfoliaY Combinator
Portfolio news
latest coverage across their companiesAluna · apgcapitalmarkets.com · Sep 28, 2025
Frequently asked questions
- How many investments has Blue Bear Ventures made?
- Blue Bear Ventures has 27 tracked investments.
- What stage does Blue Bear Ventures invest at?
- Blue Bear Ventures invests at the Pre-Seed, Seed, Series A stages.
- What is Blue Bear Ventures's typical check size?
- Blue Bear Ventures typically writes checks of $100K – $400K.
- What sectors does Blue Bear Ventures focus on?
- Blue Bear Ventures focuses on AI & Machine Learning, Biotech, Cleantech, Climate Tech, Deep Tech, Energy, Hardware, Healthtech, New Materials.
- Where is Blue Bear Ventures located?
- Blue Bear Ventures is headquartered in San Francisco, US.
- Does Blue Bear Ventures lead rounds?
- Blue Bear Ventures typically participates in rounds rather than leading them.
- Who does Blue Bear Ventures co-invest with?
- Blue Bear Ventures most often shares deals with Y Combinator, Abstract Ventures, Artis Ventures, among 70 tracked co-investors.
Media · Podcasts & interviews
featuring the teamDeepak Gupta, Partner Blue Bear Ventures #buildfintechbusiness
FinTech Silicon Valley · Deepak Gupta
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