What stage does R42 Group invest at?

R42 Group invests at the Pre-Seed, Seed, Series A, Series B stages.

Where is R42 Group located?

R42 Group is headquartered in San Francisco.

Does R42 Group lead rounds?

Yes, R42 Group leads investment rounds.

R42 Group

Family office

San Francisco · Pre-Seed–Series B · 13 people tracked

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✨ Fox Verdict

Investment thesis

R42 focuses on artificial intelligence and science, drawing on a team of scientific advisors and the experience of founder Dr. Ronjon Nag. The firm operates a dual strategy: it invests directly in early-stage companies, leading and backing them from the earliest stages — even when a startup is only an idea without a team — and it invests as a limited partner in funds that share its values, sometimes co-investing alongside those funds. R42 has backed roughly 50 companies, providing founders with hands-on guidance, resources, and access to expert advisors to help accelerate their growth.

Invests inAI & Machine Learning Biotech Deep Tech Hardware Healthtech Longevity SaaS San Francisco

Source: firm website, verified Aug 16, 2026.

Stage

Pre-Seed–Series B

San Francisco

Leads rounds

Leads

Instruments

Equity

Founded

2004

Team · 13 people

from the firm's website & public directories

Ronjon Nag· Founder

Dr. Ronjon Nag is an entrepreneur and AI pioneer who cofounded and advised companies acquired by Motorola, BlackBerry, and Apple. He established R42 out of his family office.

Anastasiya Giarletta· Principal· Los Angeles Metropolitan Areain

Principal at R42 Group who evaluates companies in longevity science and artificial intelligence.

Anne Friedlander· Adjunct Professor, Human Biology, Stanford University

Adjunct Professor in Human Biology at Stanford University and an advisor to the firm.

Artem Trotsyuk· Entrepreneur in Residence

Bioengineer and computer scientist who studied at UC Davis and earned a PhD in BioEngineering from Stanford University.

Eric Saund· Cognitive Science Researcher, AI/ML Consultant

Researcher in cognitive science and a consultant in AI and machine learning.

Frank Sortino· Director, Pension Research Institute

Director at the Pension Research Institute and creator of the Sortino Ratio.

Joel Naor· Entrepreneur in Residence

Physician executive with extensive experience across large, small, and early-stage biotech companies, having served as chief medical officer for public and private firms developing biologics, small molecules, stem cells, and other therapies.

Michael Snyder· Stanford Professor, Chair of Genetics Department

Stanford Ascherman Professor and Chair of the Genetics Department.

Pavan Manocha· Sustainability & Longevity Investor; Yoga for Aging Prevention Researcher

Certified yoga teacher and scholar on the science of yoga in aging prevention, serving as an adjunct professor, venture investor, and limited partner at R42 Group.

Rickmer Kose· Nanotechnology Expert; LiDAR, Autonomous Vehicles

Advisor with over 30 years of experience in technology and entrepreneurship, specializing in nanotechnology, LiDAR, and autonomous vehicles.

Sohila Zadran· Entrepreneur, Expert in Biotechnology and Digital Health

Entrepreneur and expert in biotechnology and digital health who studied Molecular Cell Biology at UC Berkeley.

Steve Toteda· Global Executive in Water, Energy and Communications Technology

Global executive with 25 years of leadership experience in the water, energy, and communications sectors.

Zixuan An· Venture Associate

Supports fund operations, portfolio management, growth strategy, and investor relations. Holds BA degrees in Psychology and Philosophy from UC Santa Cruz and a tech-intensive MBA from Cornell University.

Frequently asked questions

What stage does R42 Group invest at?: R42 Group invests at the Pre-Seed, Seed, Series A, Series B stages.
What sectors does R42 Group focus on?: R42 Group focuses on AI & Machine Learning, Biotech, Deep Tech, Hardware, Healthtech, Longevity, SaaS.
Where is R42 Group located?: R42 Group is headquartered in San Francisco.
Does R42 Group lead rounds?: Yes, R42 Group leads investment rounds.

Media · Podcasts & interviews

featuring the team

Can We Hack the Aging Code? Dr. Ronjon Nag on Using AI to Cure Cancer & Extend Life- R42 Group

Ones Changing The World - 1CW · Ronjon Nag

Images

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