Spero Ventures
Venture capitalBurlingame Β· SeedβSeries A Β· 6 people tracked
Investment thesis
Spero Ventures invests in companies where mission serves as both an accelerant and strategic advantage, enabling the business to attract talent, customers, and investors. The firm provides capital and hands-on support to founders once it identifies strong convictions in the business fundamentals and team.
Source: firm website, verified Jul 21, 2026.
Team Β· 6 people
from the firm's websiteInvestor drawn to hands-on founders who build product directly in the early stages of company development.
Co-founder focused on identifying real-world problems for people and the planet, then sourcing exceptional founders working to solve them.
Co-founder of Spero Ventures, focused on ensuring technology enables people to live good lives through mission-driven entrepreneurship and meaningful business impact.
Investment professional focused on companies driving improvements in human and planetary health while fostering greater societal productivity and optimism.
Investor committed to enabling entrepreneurs to disrupt established industries through sustainable products and experiences that significantly improve upon existing solutions.
Associate supporting technologies that enhance human and planetary health outcomes, as well as platforms that improve how people connect both online and in-person.
What they invest in
from 14 of 32 portfolio companiesAI & Machine Learning Γ5Healthtech Γ5Digital Health Γ3Enterprise Software Γ3Advanced Manufacturing Γ2Biotech Γ2Circular Economy Γ2Cleantech Γ2
HQs:United StatesΓ7
Investments Β· 32 tracked
founders shown can be your intro pathBase Operations provides a platform for corporate security teams to proactively identify and analyze threats using street-level intelligence and data-driven insights. The platform enables security leaders and analysts to anticipate threats globally and make informed decisions about organizational resilience and market expansion.
CybersecurityData & InfrastructureEnterprise SoftwareSaaSWashington, US
Confirm is an AI-powered performance management platform that uses Organizational Network Analysis to map collaboration patterns and provide objective data for fairer employee reviews. The product serves HR leaders and people operations teams at growth-stage and enterprise companies seeking evidence-based talent decisions.
AI & Machine LearningEnterprise SoftwareHR TechSaaS
Jeremy Lerner
Corvus Robotics builds autonomous drones that perform warehouse inventory scanning and material handling automation for large enterprises across North America. The company develops the physical artificial intelligence systems for warehouse operations at Fortune 500 and Global 2000 companies.
Advanced ManufacturingAI & Machine LearningIoTLogistics & Supply ChainRoboticsSan Francisco, US
Jackie Wu(Founder/CEO)inKabir Mohammed
Empowerly provides college admissions counseling and application support services to help students gain admission to top universities. The company serves high school students and their families navigating the college application process.
EdTechBay Area, US
Hanmei Wu(Founder)Changxiao Xie(Co-founder)
Gencove provides direct-to-consumer genetic sequencing and polygenic risk scoring for health insights. The service analyzes DNA samples to deliver personalized health recommendations across core health areas, ancestry information, and integrates with labs, wearables, and lifestyle data.
BiotechDigital HealthHealthtech
Plug-and-play conversational AI platform enabling voice and chat interactions with information across digital channels.
Tiny Health provides microbiome testing kits and personalized health reports for families from pregnancy through adulthood, focusing on gut health optimization to address conditions like eczema, allergies, IBS, and constipation. The company emphasizes early testing during a child's first 1,000 days of life and offers diet, supplement, and lifestyle recommendations based on test results from CLIA-certified laboratory analysis.
Digital HealthHealthtechWellness & Fitness
Mast combines forest restoration with biomass burial to remove carbon and restore wildfire-affected landscapes. The company operates as an end-to-end reforestation provider, managing seed selection, seedling cultivation, and carbon sequestration across its owned nurseries and project sites.
AgTechCircular EconomyCleantechClimate TechFintechImpact & Social GoodSeattle, US
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Mobius Materials operates a certified marketplace enabling contract manufacturers and OEMs to buy and sell excess electronic components directly, addressing annual waste of $15B in discarded components despite ongoing demand. The platform serves industries including consumer electronics, oil & gas, healthcare, gaming, and industrial systems globally.
Advanced ManufacturingB2B MarketplacesCircular EconomyHardwareNew MaterialsRoboticsSan Francisco, US
Margaret Upshur(Founder and CEO)in
Oova is a clinical-grade hormone testing platform that uses smartphone scanning of test strips paired with AI-powered analysis to measure luteinizing hormone, estrogen, and progesterone levels. The service targets women tracking fertility, perimenopause, or general cycle health, with results validated by medical institutions and recommended by healthcare providers.
AI & Machine LearningDigital HealthFemTech
Persist AI provides AI-driven formulation development services for pharmaceutical compounds, combining robotic lab automation with machine learning models to accelerate drug formulation optimization and reduce time-to-market.
AI & Machine LearningBiotechHealthtechMedical DevicesSacramento, US
Sora Schools provides an engaging, personalized learning experience built by educators, designers, and engineers. The company focuses on transformative education reform and innovative learning models.
EdTech
TELO designs and manufactures the MT1, an all-electric compact pickup truck combining the capability of a Toyota Tacoma with Tesla-like range and efficiency in a Mini Cooper-sized footprint. The vehicle targets consumers seeking a practical, technically advanced EV truck for both urban and off-town use.
CleantechHardwareMobility & Transportation
Canopy develops an IoT-based wearable safety platform for healthcare organizations to protect workers from safety risks and workplace violence. The company delivers a comprehensive connected safety solution serving hospitals and healthcare systems across the United States.
Enterprise SoftwareHealthtechIoT
Shan Sinha(Co-founder & CEO)Vinay Pulim(Co-founder & Chief Technology Officer)Hemanth Meenakshisundaram(Co-founder & Chief Scientist)
Vistapath develops technology solutions to modernize pathology lab operations, helping pathology laboratories improve quality, efficiency, and consistency in critical lab processes.
AI & Machine LearningHealthtechMedical Devices
Timothy Spong(CEO & Founder)Ben Burley(COO & Founder)Jacob Guggenheim(CTO)
Frequently asked questions
- What stage does Spero Ventures invest at?
- Spero Ventures invests at the Seed, Series A stages.
- What is Spero Ventures's typical check size?
- Spero Ventures typically writes checks of $2M β $4M.
- What sectors does Spero Ventures focus on?
- Spero Ventures focuses on Cleantech, Healthtech, Impact & Social Good, Sector Agnostic.
- Where is Spero Ventures located?
- Spero Ventures is headquartered in Burlingame, US.
- Does Spero Ventures lead rounds?
- Yes, Spero Ventures leads investment rounds.
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