Spero Ventures
Venture capitalBurlingame · Seed–Series A · 6 people tracked
Also known as SPERO · SPERO MANAGEMENT COMPANY, LLC
Find your way into Spero Ventures
2,117 people in our graph share verified history with the Spero Ventures team — schools, employers, funds. One of them is your warm intro.
Investment thesis
Spero Ventures views a company's mission as a strategic advantage and accelerant, believing it gives talent, customers, and investors a compelling reason to choose the product. The firm looks to reach conviction in a business before investing, and once it does, it champions the founders and their teams by backing them with both capital and time. The emphasis is on partnering closely with mission-oriented teams rather than on a specific sector or stage focus stated on this page.
Source: firm website, verified Sep 15, 2026.
Team · 6 people
from the firm's website
What they invest in
from 41 of 55 portfolio companiesAI & Machine Learning ×16SaaS ×10Cleantech ×9Climate Tech ×9Energy ×7Healthtech ×7HR Tech ×5Advanced Manufacturing ×4
HQs:United States×29France×2Mexico×1
Who they back
founder profiles across 21 portfolio companiesFounding team size:solo founder×82 founders×53 founders×64+ founders×2
Where their founders studiedfrom 33 founders with education data
Cornell ×3Massachusetts Institute of Technology ×3University of California, Berkeley ×3Yale University ×2
What their founders studiedfrom 34 founders with field-of-study data
Engineering ×9Computer Science ×8Life Sciences ×5Business & Management ×3Chemistry ×2Design & Architecture ×2
Where their founders worked beforefrom 35 founders with career history
Goldman Sachs ×3Little Universe ×2National Energy Partners ×2New York Genome Center ×2Zymergen ×2
Accelerator rootsportfolio companies that came through a program
9 founders hold a PhD · 1 hold an MBA (of 33 with degree data)
Investments · showing 48 of 55
founders shown can be your intro pathBy year:2026 · 22025 · 32024 · 22023 · 32022 · 42021 · 22020 · 32019 · 12018 · 22011 · 123 dated
Leaf is a unified API platform that aggregates and standardizes data from farm equipment, IoT sensors, and agricultural data sources in proprietary formats.
AgTechData & InfrastructureSaaS
Bailey StockdaleJoseph AlbertsinLuiz Santana
Co-investorsRadicle GrowthS2G InvestmentsTrailhead Capital
Corvus Robotics builds autonomous drones that perform warehouse inventory scanning and material handling automation for large enterprises across North America.
Advanced ManufacturingAI & Machine LearningIoTLogistics & Supply ChainRoboticsSan Francisco, US
Jackie Wu(Founder/CEO)inKabir Mohammed(Director)inMohammed Kabir(Director)in
BoardArthur Chow(Director)in
Board seatShripriya Mahesh· per SEC Form D
Co-investorsY CombinatorCathexis Venturesf7 VenturesGoAhead VenturesOne Way VenturesS2G Investments+1 more
Gencove provides direct-to-consumer genetic sequencing and polygenic risk scoring for health insights.
BiotechDigital HealthHealthtechNew York, US
Tomaz Berisa(Executive Officer, Director)inJoseph Pickrell(Executive Officer, Director)in
Board seatSara EshelmanShripriya Mahesh· per SEC Form D
Co-investorsBread And Butter Ventures, LlcBalaji SrinivasanRefactor CapitalThird Kind Venture CapitalVersion One Ventures
San Francisco, US
Shelby Clark(Director)inAndre Haddad(Executive Officer, Director)Anne Dorman(Executive Officer)in
BoardDeepak Kamra(Director)inHoward Hartenbaum(Director)inJoe Kraus(Director)in
Board seatShripriya Mahesh· per SEC Form D · $35.2M raise · filed Mar 2022
Co-investorsAugust CapitalCanaan PartnersGV (Google Ventures)Shasta Ventures
New York, US
Ryan Schulke(Director)Ari Kassman(Executive Officer, Director)
Board seatShripriya Mahesh· per SEC Form D · $2M raise · filed Jul 2018
Singularity Energy provides tools for measuring grid emissions and supporting decision-making around decarbonization.
CleantechClimate TechEnergyCambridge, US
Wenbo Shi(Executive Officer, Director)in
Board seatMarc Tarpenning· per SEC Form D
Co-investorsEnergy Impact PartnersThird Sphere
Wattch provides a software and hardware platform for monitoring, intelligence, and control of renewable energy assets such as solar and storage, including a Hybrid SCADA system, digital twin analytics, and AI-optimized dispatch.
AI & Machine LearningCleantechEnergyIoTSaaSSmyrna, US
Jared Duncan(Founder)inRobert Alexander Nussey(Executive Officer, Director)
Board seatMarc Tarpenning· per SEC Form D
Co-investorsVoLo Earth Ventures
Alex Sandoval(Founder)Nicolas Hernan Degiorgis(Founder)
Co-investorsBDev VenturesVoyager Partners
Aralez Bio produces noncanonical amino acids using biocatalysis, including compounds that add rigidity to peptide backbones and increase enzyme resistance.
BiotechCleantechClimate TechDeep TechNew MaterialsBerkeley, US
Tina Boville(Co-founder & CEO)inDavid Romney(Co-founder)inFrances Arnold(Co-founder / Scientific Founder)
Co-investorsAstiaFifty YearsFREEFLOWGood Growth CapitalISVJuniper+1 more
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Base Operations provides a platform for corporate security teams to proactively identify and analyze threats using street-level intelligence and data-driven insights.
CybersecurityData & InfrastructureEnterprise SoftwareSaaSWashington, US
Co-investorsTechstars
BrainsGate develops a neurostimulation therapy for stroke patients based on stimulation of the sphenopalatine ganglion (SPG) to increase cerebral blood flow.
BiotechHealthtechMedical Devices
Co-investorsAgate Medical Investments LPCipio PartnersJJDCPitango
Canopy develops an IoT-based wearable safety platform for healthcare organizations to protect workers from safety risks and workplace violence.
Enterprise SoftwareHealthtechIoTPalo Alto, US
Shan Sinha(Co-founder & CEO)inVinay Pulim(Co-founder & Chief Technology Officer)inHemanth Meenakshisundaram(Co-founder & Chief Scientist)in
Co-investors25MadisonACME CapitalFounder CollectiveNextView Ventures
Clarity provides air quality sensing-as-a-service solutions, combining hardware air pollution sensors with cloud-based monitoring software and consulting services for organizations and communities measuring air quality.
CleantechClimate TechData & InfrastructureHardwareIoT
BoardMinette NavarreteinRamanan RaghavendraninMarc Tarpenningin
Co-investorsBlue Bear VenturesKickstart VenturesSoundproof VenturesHumba VenturesLMNT VenturesRegeneration.VC
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Confirm is an AI-powered performance management platform that uses Organizational Network Analysis to map collaboration patterns and provide objective data for fairer employee reviews.
AI & Machine LearningEnterprise SoftwareHR TechSaaSSan Francisco, US
Josh Merrill(Founder)inJeremy Lerner
Co-investorsResolute VenturesScribble VenturesWestern Technology InvestmentAccomplice
Eli simplifies access to home energy programs through software that streamlines complex workflows in clean energy and electrification.
AI & Machine LearningClimate TechEnergyFintechSaaS
Jeff Coleman(CEO & Co-Founder)inAdrian Del Balso(Head of Product & Co-Founder)inEduardo Del Balso(Head of Engineering & Co-Founder)in
Co-investorsCity LightLowercarbon CapitalR/GA VenturesUP Partners
Empowerly provides college admissions counseling and application support services to help students gain admission to top universities.
EdTechBay Area, US
Hanmei Wu(Founder)inChangxiao Xie(Co-founder)
Co-investorsAzure Capital PartnersBrighter CapitalConductive VenturesScrum VenturesTransLink CapitalFJ Labs+2 more
Euclid is a venture capital firm focused on Vertical AI, providing research-driven insights and investing in companies building vertical AI software.
AI & Machine LearningPalo Alto, US
William Smith(Executive Officer, Director)inNic Poulos(Founder)in
BoardMichael Dearing(Director)Patrick Chung(Director)
Co-investorsDeep AcreCommonweal VenturesDesigner FundToba CapitalVenrock
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Euclid provides software and services for renewable energy teams, including a platform that extracts and structures data from project documents into costs, risks, requirements, and action items.
CleantechClimate TechEnergySaaSNew York City, US
Jacob Sandry(Cofounder)inBrian DeMaio(Founder)inRyan Guay(Founder)in
Co-investorsBridges Fund Management Ltd.Coalition OperatorsCommonweal VenturesDesigner FundNextView VenturesToba Capital+1 more
Guide helps job seekers find meaningful work by making job search more transparent and enjoyable.
AI & Machine LearningFuture of WorkHR TechSaaS
Austin
Co-investorsScribble Ventures
Huckleberry offers a baby tracker app and sleep support that combines pediatric sleep experts with AI to build custom sleep plans for families.
AI & Machine LearningConsumerDigital Health
Seng Oon Toh(Founder)
Co-investorsCity LightTamarisc VenturesVela PartnersThe Fund
Huckleberry provides coaching services designed to make professional development accessible to all employees, not just senior leadership, with coaching delivered in real-time within workflows rather than through scheduled sessions.
AI & Machine LearningEnterprise SoftwareFuture of WorkHR TechSaaS
Aaron Ward(Founder)in
Co-investorsOregon Venture FundTamarisc Ventures
Plug-and-play conversational AI platform enabling voice and chat interactions with information across digital channels.
Israel Krush(Founder & CEO)inRom Cohen(Founder)in
Co-investorsBlack Opal VenturesDefine VenturesDorm RoomEntrepreneurs Roundtable Accelerator (ERA)Hanaco Venture CapitalHealthier Capital+7 more
Juno provides disability insurance for children under 26 in the United States, offering financial protection and support to parents managing a child's severe illness or disability.
FintechHealthtechHR TechInsurTechBay Area, US
Jordan Epstein(Cofounder)inSnae(Cofounder)BillDanMeghanSnaebjorn Gunnsteinsson(Cofounder)in
Co-investorsFloating PointImmeasurableNVP CapitalNewark Venture Partners
Mast combines forest restoration with biomass burial to remove carbon and restore wildfire-affected landscapes.
AgTechAI & Machine LearningCircular EconomyCleantechClimate TechFintechImpact & Social GoodSeattle, US
Grant Canary(Founder)in
Co-investorsAsymmetry VenturesChrysalixDcode CapitalGENIUS NYKeiki CapitalPulse Fund+8 more
Möbius Exchange is a Mantle-native StableSwap decentralized exchange for swapping stablecoins and pegged assets with low slippage, using an Asset Liability Management model that supports single-sided liquidity provision and open, multi-asset pools.
Crypto & Web3Fintech
Co-investorsBitDAOMantle NetworkMotive PartnersREFASHIOND Ventures
Mobius Materials operates a certified marketplace enabling contract manufacturers and OEMs to buy and sell excess electronic components directly, addressing annual waste of $15B in discarded components despite ongoing demand.
Advanced ManufacturingB2B MarketplacesCircular EconomyHardwareNew MaterialsRoboticsSan Francisco, US
Margaret Upshur(Founder)in
Co-investorsLighthouse Network Ventures LlcOutsidersUndeterred CapitalY CombinatorREFASHIOND Ventures
Oova offers a clinical-grade at-home hormone test that pairs with an AI-powered app to measure LH, estrogen (E3G), and progesterone (PdG) levels from urine, scanned via a smartphone camera.
AI & Machine LearningDigital HealthFemTech
Amy Divaraniya(Founder & CEO)inAparna (Amy) Divaraniya, PhD(Founder)in
Co-investorsBBG VenturesConnecticut InnovationsKluz VenturesSamsung NextHelm
Persist AI provides AI-driven formulation development services for pharmaceutical compounds, combining robotic lab automation with machine learning models to accelerate drug formulation optimization and reduce time-to-market.
AI & Machine LearningBiotechHealthtechMedical DevicesRoboticsSacramento, US
Karthik Raman(Founder)inChristopher Shelner(Founder)in
Co-investors2048 VenturesGlobal BrainGood AI CapitalJovonoY CombinatorInnospark Ventures+1 more
Pickaxe is a no-code platform for building, packaging, and deploying custom AI agents.
AI & Machine LearningCreator EconomyDeveloper ToolsSaaS
Nathaniel Mahowald(Founder)in
Co-investorsSwift Ventures
Remark provides AI-powered customer support and shopping assistance for e-commerce businesses, using AI personas to answer shopper questions and resolve support tickets while routing complex cases to human agents.
AI & Machine LearningE-commerceRetail TechSaaS
Theo Satloff(Co-founder & CEO)inCarl-Philip Majgaard(Co-founder & Tech Lead)Ian Patterson(Co-founder & Sales)in
Co-investorsInspired CapitalShine CapitalStripeSugar CapitalVisible Ventures
Sora Schools provides an engaging, personalized learning experience built by educators, designers, and engineers.
EdTech
Co-investorsContraryHoneystone VenturesUnion Square Ventures (USV)Inspired CapitalNew Enterprise Associates (NEA)Peak State Ventures+3 more
Sora is a labor compliance platform that digitizes and manages employee records for companies in Mexico, using AI agents to advise on labor decisions, generate documents based on the Federal Labor Law (LFT), and provide legally valid electronic signatures with facial biometrics.
AI & Machine LearningHR TechLegalTechMonterrey, MX
Co-investorsAct One VenturesInspired Capital
Sora Ventures is an Asia-based investment firm that acquires and operates publicly traded companies while implementing Bitcoin treasury strategies and backing web3 and digital asset infrastructure.
Crypto & Web3
Co-investorsSerafundInspired Capital
Sora turns companies' unused office space into fully managed, turnkey offices through a service offering, letting hosts generate revenue while delegating the management of shared occupancy.
MarketplacesPropTechParis, FR
Romain Allouch(Founder)in
Co-investorsDaphniInspired Capital
Sora Fuel produces sustainable aviation fuel (SAF) and diesel using a proprietary closed-loop direct air capture and conversion process that draws carbon from air rather than biomass or industrial feedstocks.
CleantechClimate TechEnergyCambridge, US
Curtis BerlinguetteinGareth Ross(Executive Officer, Director)inCurtis Belinguete(Director)
BoardPatrick Sarver(Director)inMarc Tarpenning(Director)inMichael Kearney(Director)in
Co-investorsInnovation UBCInspired CapitalLeitmotifThe Engine VenturesWireframe Ventures
TalkShop.live is a live shopping platform where users watch live video streams and buy featured products directly during the broadcast, using its patented shoppable embedded point-of-sale technology.
E-commerceMedia & EntertainmentRetail Tech
Bryan Moore(Founder)inTina Moore(Founder)in
Co-investorsFlucas VenturesFourth RealmProgress Ventures
TELO Trucks builds the MT1, an all-electric compact pickup that combines pickup-truck utility with EV range and advanced safety technology in a subcompact footprint.
CleantechHardwareMobility & Transportation
Co-investorsE12 Venture Capital, LlcGoAhead VenturesTO VC
Tiny Health offers at-home gut and vaginal microbiome test kits with age-specific, evidence-based reports that recommend diet, supplement, and lifestyle changes.
Digital HealthHealthtechWellness & Fitness
Cheryl Sew Hoy(Founder)in
Co-investorsAlumni VenturesB Capital GroupB4 CapitalCartan CapitalModi VenturesNext Coast Ventures+8 more
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Vistapath develops technology solutions to modernize pathology lab operations, helping pathology laboratories improve quality, efficiency, and consistency in critical lab processes.
AI & Machine LearningHealthtechMedical DevicesCambridge, US
Timothy Spong(CEO & Founder)inBen Burley(COO & Founder)inBurley Benjamin(Executive Officer, Director)Spong Timothy(Executive Officer, Director)inJacob Guggenheim(CTO)in
Co-investorsCota CapitalFirst Star VenturesMoxxie VenturesNextGen Venture PartnersScribble VenturesValuestream Ventures
Personal website of Marc Tarpenning, an engineer and co-founder of NuvoMedia and Tesla, who now works as a Venture Partner at Spero Ventures investing in early-stage startups.
Deep Tech
BoardMarc Tarpenning(Venture Partner (Spero Ventures); Co-founder (NuvoMedia, Tesla))in
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Clarity MovementCore WellnessOlden Labs PBCOpen GardenTortuga Agricultural TechnologiesLeafMatiRevUp Software
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Portfolio news
latest coverage across their companiesEli · citybiz.co · Aug 18, 2026
Sora · the-decoder.com · Aug 17, 2026
Open Garden · thisisthecoast.co.uk · Aug 17, 2026
Clarity · finsmes.com · Aug 14, 2026
Pickaxe · cbsnews.com · Jul 21, 2026
Tiny Health · zeebiz.com · Jul 16, 2026
Mati · finsmes.com · Jun 29, 2026
Frequently asked questions
- How many investments has Spero Ventures made?
- Spero Ventures has 55 tracked investments, 1 of which have exited, including 9 dated in the last 24 months.
- What stage does Spero Ventures invest at?
- Spero Ventures invests at the Seed, Series A stages.
- What is Spero Ventures's typical check size?
- Spero Ventures typically writes checks of $2M – $4M.
- What sectors does Spero Ventures focus on?
- Spero Ventures focuses on Advanced Manufacturing, AgTech, Circular Economy, Cleantech, Climate Tech, Digital Health, Energy, FoodTech, Future of Work, Healthtech, Impact & Social Good, Longevity, Mobility & Transportation, Sector Agnostic, Wellness & Fitness.
- Where is Spero Ventures located?
- Spero Ventures is headquartered in Burlingame, US.
- Does Spero Ventures lead rounds?
- Yes, Spero Ventures leads investment rounds.
- Who does Spero Ventures co-invest with?
- Spero Ventures most often shares deals with Scribble Ventures, Y Combinator, GoAhead Ventures, among 98 tracked co-investors.
Media · Podcasts & interviews
featuring the teamSpero Ventures, General Partner: Shripriya Mahesh’s Leadership Backstory
The Leadership Backstory · Shripriya Mahesh
#newtovc Interview Series with Andrew Parker of Spero Ventures
nextNYC · Andrew Parker
Conversation with Shripriya Mahesh, VC and Founding Partner at Spero Ventures.
Irina Gokh · Shripriya Mahesh
Conversation with Marc Tarpenning, the co-founder of Tesla and Venture Partner at Spero Ventures
Irina Gokh · Marc Tarpenning
Inside the mind of Shripriya Mahesh, Founding Partner, Spero Ventures
The Neon Show · Shripriya Mahesh
498th 1Mby1M Roundtable August 13, 2020: With Shripriya Mahesh, Spero Ventures
1Mby1M Roundtables · Shripriya Mahesh
Co-investors · 53
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▶41 more co-investors
Founders FundLightspeed Venture PartnersBessemer Venture PartnersIndex VenturesUncork CapitalBenchmarkFirst Round CapitalMenlo VenturesBoxGroupKrakenGreat Oaks Venture CapitalSOSVOffline VenturesBling CapitalObvious VenturesIA Ventures8VCRed Swan VenturesHomebrewGSV AccelerationFootworkNext Play VenturesQualcomm VenturesVine VenturesJackson Square VenturesK9 VenturesOwl VenturesChicago VenturesNotation CapitalRubicon Venture CapitalWormhole CapitalRoot Ventures Manager, LlcLearn CapitalVista Venture PartnersGrotech VenturesGPO FundLooking Glass CapitalRackhouse Venture CapitalVantagePoint Capital PartnersBrand New MatterCyberlaunch
Firms observed investing alongside Spero Ventures, from public investor directories. Shared companies are the overlap with Spero Ventures's recorded portfolio.
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