Deep Future

Advanced 2D materials for chips

Alden Scientific offers an AI-powered platform that harmonizes, quality-controls, and aligns fragmented multi-omic, clinical, immune, and longitudinal biological datasets to make measurements comparable across studies, populations, and time.

AI & Machine LearningBiotechDigital Health

PartnerPablos Holman· solo GP

Co-investorsiSelect FundquadraScope Venture FundService Provider Capital

Applied Physics is an independent public benefit research institute that conducts and commercializes research across fields including astrophysics, aerospace defense, electromechanical engineering, machine learning, quantum mechanics, and materials science.

Deep TechQuantum ComputingSpace Tech

PartnerPablos Holman· solo GP

Aurenar develops a non-invasive, ear-worn neuromodulation wearable that stimulates a nerve in the ear to boost the body's natural control of inflammation, targeting complications in intensive care unit patients.

HardwareHealthtechMedical Devices

Eric Leuthardt(Chief Executive Officer & Founder)inJenna Gorlewicz(Chief Technology Officer & Founder)inAnna Huguenard(Chief Medical Officer & Founder)inJesse Wheeler(Chief Operations Officer)inRyan Kight(Chief Financial Officer)in

PartnerPablos Holman· solo GP

Co-investorsKaleida CapitalSolas BioVentures

Casimir develops chips that harvest ambient energy to power devices without batteries, cords, or charging.

EnergyHardwareSemiconductors

Sonny(Founder)in

PartnerPablos Holman· solo GP

Co-investorsDraper AssociatesIBX

CreateMe is an AI robotics company that manufactures apparel using robots and digital microadhesives instead of thread, enabling on-demand, smaller-batch production that reduces inventory waste and shortens supply chains.

Advanced ManufacturingAI & Machine LearningRobotics

PartnerPablos Holman· solo GP

CSignum develops wireless communication technology using electromagnetic field signaling for underwater and subsurface monitoring, enabling data transmission from seabeds, riverbeds, and ship hulls in environments where traditional wireless systems fail.

IoT

PartnerPablos Holman· solo GP

Co-investorsRaptor Group

PartnerPablos Holman· solo GP

Descycle develops metals processing infrastructure and closed-loop manufacturing solutions with digital traceability for supply chain resilience.

Advanced ManufacturingCircular EconomyDefense Tech

PartnerPablos Holman· solo GP

Co-investorsKero Development PartnersTSP VenturesVorwerk Ventures

DMAT produces durable, self-healing concrete and mortar with reduced CO2 emissions, inspired by ancient Roman techniques, for the construction industry.

CleantechConstruction TechNew MaterialsCambridge, IT

Paolo Francesco Sabatini(Executive Officer, Director)

PartnerPablos Holman· solo GP

Co-investorsSafar Partners

EvoChip develops AltiCore, a patented mathematical framework that runs AI models as logic-dominant operator chains instead of arithmetic-heavy neural networks, targeting efficiency and deterministic execution.

AI & Machine LearningDeep TechSemiconductorsDana Point, US

PartnerPablos Holman· solo GP

Holobiome discovers and develops therapies derived from the human gut microbiome, working to translate microbiome science into probiotics and targeted treatments for whole-body health.

AI & Machine LearningBiotechHealthtechLongevityBoston, US

Philip Strandwitz(Co-founder & Director, Chief Executive Officer)inKim Lewis(Co-founder, Director)Mike La Fleur(President, Co-founder, Director)Michael LaFleur(Executive Officer)

BoardJoan LaRovere(Director)inIain Chessell(Director)

PartnerPablos Holman· solo GP

Co-investorsAble PartnersBantam GroupHealthtech CapitaliSelect FundPace VenturesAlexandria+3 more

KLIR Sky, Ltd. develops a pollution reduction machine and offers a "Pollution Reduction as a Service" (PRaaS) model aimed at capturing greenhouse gas emissions at the source before they reach the atmosphere.

CleantechClimate TechHardware

PartnerPablos Holman· solo GP

Lab 91 develops semiconductor processes and devices based on 2D materials such as MoS2.

Deep TechNew MaterialsSemiconductorsAustin, US

PartnerPablos Holman· solo GP

Co-investorsMonozukuri Ventures

Ladon Robotics develops autonomous cargo ships powered by wind and solar energy, using solar-coated wingsails and battery storage to move freight and reduce crew and fuel costs.

CleantechLogistics & Supply ChainRobotics

PartnerPablos Holman· solo GP

MacroX transforms high-frequency alternative data into real-time economic measurements for investors and institutions, providing interpretable insights on growth, inflation, labor, and consumer conditions globally.

AI & Machine LearningData & InfrastructureFintech

PartnerPablos Holman· solo GP

Co-investorsArgon Ventures

Marvel Labs builds vertically integrated, autonomous microfactories — mobile, field-deployable production lines with modular units for intake, formulation, forming, and automated QC, controlled by physical AI running closed-loop process control.

Advanced ManufacturingAI & Machine LearningRoboticsSouth San Francisco, US

PartnerPablos Holman· solo GP

Co-investorsAsimov Ventures

Nanize develops PFAS-free polysilazane coating formulations and curing technology that cure in under a minute below 70°C, producing hard, scratch-resistant, low-friction coatings.

Advanced ManufacturingCleantechNew Materials

PartnerPablos Holman· solo GP

Nano confinement fusion energy

New Carbon Inc. (dba Darwin Carbon) is an advanced materials manufacturer producing carbon microfiber products—sheets, tapes, wires, and yarns—that combine structural, electrical, and thermal performance to replace metals, plastics, and concrete.

Deep TechDefense TechNew Materials

Michael Gurau(Co-founder & CEO)inDavid Gailus(Co-founder & CTO)

PartnerPablos Holman· solo GP

Next generation semiconductor lithography

Nuri develops an implantable emotion brain-computer interface (eBCI) for psychiatry that uses a closed-loop neuromodulation protocol called Deep Brain Recoding to detect, decode, and recalibrate trauma responses at the neuronal level.

Deep TechHealthtechMedical Devices

PartnerPablos Holman· solo GP

Co-investorsIsrael Innovation Authority

ParaNetics appears to develop electric propulsion technology with applications for aircraft, submersibles, and other uses.

Deep TechHardwareMobility & Transportation

PartnerPablos Holman· solo GP

Quorum Earth develops biopesticides aimed at controlling invasive insects, with an initial focus on protecting bees.

AgTechBiotechClimate Tech

PartnerPablos Holman· solo GP

Co-investorsLOI Venture

RISC Zero provides verifiable computation technology that lets anyone cryptographically confirm a computation's output is correct without recomputing it, while preserving privacy.

Crypto & Web3CybersecurityDeep TechSeattle, US

Frank Laub(Executive Officer, Director)inBrian Retford(Executive Officer, Director)Jeremy Bruestle(Executive Officer, Director)

PartnerPablos Holman· solo GP

Co-investorsBain Capital CryptoBlockchain CapitalD1 VenturesFenbushi CapitalFigmentL2 Iterative Ventures (L2IV)+3 more

Spar Systems builds waste-heat-to-power infrastructure for data centers through its SPRING platform, converting data center waste heat into on-site power while improving thermal management and energy efficiency.

CleantechEnergyHardwareNew York, US

PartnerPablos Holman· solo GP

Spatial imagination for robots

Terran Robotics builds robotic systems that construct homes using adobe (earth-based) materials, offering an alternative to stick-frame construction.

Construction TechPropTechRobotics

PartnerPablos Holman· solo GP

True recycling for mixed plastic

Unquestionably safe nuclear reactors

Virtus Solis is developing a space-based solar power system that collects solar energy in orbit and beams it to receivers on Earth as a firm, dispatchable power source.

CleantechEnergySpace Tech

PartnerPablos Holman· solo GP

Co-investorsMichigan RiseSeraphim Space