Headwater Ventures
Venture capitalActively deployingMinneapolis · Pre-Seed–Seed · 1 people tracked
Investment thesis
Headwater invests in preseed and seed teams building software infrastructure and intelligence that make care administratively simpler, clinically safer, and financially clearer. It focuses on companies operating in the connective tissue between payers, providers, patient access, and operational workflows, favoring systems that can become repeatable defaults within regulated healthcare environments. The firm explicitly avoids pharma, biotech, medtech, and life sciences, concentrating instead on the software layer of health.
Source: firm website, verified Aug 7, 2026.
Team · 1 people
from the firm's website
What they invest in
from 39 of 40 portfolio companiesHealthtech ×36Digital Health ×28AI & Machine Learning ×17SaaS ×10Enterprise Software ×6InsurTech ×4Fintech ×2Medical Devices ×2
HQs:United States×25United Kingdom×2
Who they back
founder profiles across 20 portfolio companiesFounding team size:solo founder×122 founders×63 founders×2
Where their founders studiedfrom 11 founders with education data
Princeton University ×2Queen Elizabeth's School, Barnet ×2Stanford University Graduate School of Business ×2University of Cambridge ×2
Where their founders worked beforefrom 11 founders with career history
UCSF Medical Center ×2
Accelerator rootsportfolio companies that came through a program
Investments · 40 tracked
founders shown can be your intro pathBy year:2025 · 32024 · 12022 · 22019 · 28 dated
Affineon offers an AI-powered inbox tool that works within electronic health record systems to automatically handle lab results and prescription renewals for healthcare providers and their care teams.
AI & Machine LearningDigital HealthHealthtech
PartnerMatt Miller· solo GP
Co-investorsAI FundBenhamou Global VenturesCity LightLoup VenturesSignal Peak Ventures
Andy is an AI-powered ambient scribing platform for home health agencies that automates clinical documentation, compliance checks, and medical coding.
AI & Machine LearningHealthtechSaaSSan Francisco, US
Tiantian Zha(Founder)in
PartnerMatt Miller· solo GP
Co-investorsf7 VenturesIA Seed VenturesInformed Ventures Advisors, LlcY Combinator
Automate Clinic is a multi-specialty medical group offering specialized, insurance-accepted care delivered remotely from patients' homes with continuity from a dedicated doctor.
Digital HealthHealthtech
PartnerMatt Miller· solo GP
Bridge provides infrastructure for digital health and virtual care providers to accept insurance, offering a nationwide multi-specialty in-network provider network, a 50-state professional corporation model for credentialing and enrollment, and a real-time eligibility engine.
Digital HealthHealthtechInsurTech
PartnerMatt Miller· solo GP
Credo Health is an AI-powered SaaS platform that helps physicians, medical service organizations, accountable care organizations, and health plans with patient diagnosis and treatment.
AI & Machine LearningDigital HealthSaaS
PartnerMatt Miller· solo GP
Co-investorsFCA Venture PartnersFirstMile VenturesHannah Grey VenturesSpringTime Ventures
Cured builds cloud-based enterprise software for healthcare organizations to modernize operations and improve patient and employee experiences.
AI & Machine LearningCloud ComputingDigital HealthEnterprise SoftwareHealthtechMarketing TechSan Francisco, US
Rohit(Co-Founder and Chief Customer Officer)inAshmer Aslam(Executive Officer, Director)inAndrew Sawyer(Executive Officer, Director)in
PartnerMatt Miller· solo GP
Co-investorsHigh Alpha
Defiant Health provides accelerated cancer care navigation, coordinating diagnostic testing, expedited specialist referrals, and care-plan reviews using the clinical standards of Dana-Farber Cancer Institute.
Digital HealthHealthtech
PartnerMatt Miller· solo GP
Co-investorsAmboy Street VenturesCity LightHannah Grey Ventures
Develop Health automates prior authorization and benefit verification for healthcare providers across EHRs and payers, while providing access intelligence to pharmaceutical manufacturers.
AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechMenlo Park, US
Mel van Londen(Co-Founder & CEO)inBen Easton(Co-Founder & CTO)Benjamin Easton(Founder)in
PartnerMatt Miller· solo GP
Co-investorsAnalog VenturesMTECH CAPITALWingAfore CapitalSouth Park Commons
Dune Health offers a telehealth service that analyzes data from patients' wearable devices with AI to generate medical insights, which its doctors use to create and adjust personalized care plans.
AI & Machine LearningDigital HealthHealthtechSan Francisco, US
PartnerMatt Miller· solo GP
Co-investorsDiaspora Ventures
Menlo Park, US
Bobby Guelich(Founder)inMatthew Weinberg(Director)Liyuan Huang(Executive Officer)
PartnerMatt Miller· solo GP
Co-investorsAlleyCorpFloating PointNew Enterprise Associates (NEA)TMVAlley Robotics Ventures
Felt provides clinical infrastructure delivered as an SDK/API that lets consumer app and hardware companies embed white-label healthcare—provider network, pharmacy fulfillment, HIPAA compliance, and BAA/licensing—inside their own branded products.
Digital HealthHealthtechSaaS
PartnerMatt Miller· solo GP
Ferrum Health develops AI accountability solutions, though the specific products and customer base are not detailed on the company page.
AI & Machine LearningDigital HealthEnterprise SoftwareSunnyvale, US
Pelu Tran(Executive Officer, Director)in
BoardPatrick Steele(Director)inJaclyn Hester(Director)inKenneth Ko(Director)
PartnerMatt Miller· solo GP
Co-investorsBlumberg CapitalFoundryInformed Ventures Advisors, LlcUrban InnovationGSR
Fincura AI automates insurance accounts receivable for healthcare practices, ingesting ERA 835 files, matching payments to claims, posting to practice management systems, and reconciling bank deposits.
AI & Machine LearningFintechHealthtech
Tim Schuermer(Founder (Commercial))in
PartnerMatt Miller· solo GP
Co-investorsPanache Ventures
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Gather Health provides primary care services with integrated social and home-based support for older adults in underserved communities.
Digital HealthHealthtech
PartnerMatt Miller· solo GP
Co-investorsHC9 VenturesKhosla VenturesMaverick Ventures
Glass Health provides an AI platform that assists clinicians in generating diagnostic hypotheses and developing treatment plans.
AI & Machine LearningHealthtechSaaSSan Francisco, US
Dereck Paul(Founder/CEO)inWilliam Hart(Founder/CTO)inBrett Plotzker(Executive Officer, Director)Jeremy Bluvol(Executive Officer)
BoardHari Sundram(Director)Jeffrey Parkinson(Director)
PartnerMatt Miller· solo GP
Co-investorsBreyer CapitalY CombinatorInitialized Capital
Gratia Health offers an employee engagement platform for healthcare organizations that uses gamification, smart rewards, and real-time recognition to reinforce behaviors like shift reliability, safety, and patient experience.
HealthtechHR TechSaaS
PartnerMatt Miller· solo GP
Co-investors25MadisonCity LightJumpstart Capital
Helm Health provides benefit design and member engagement tools for health plans, incorporating cost and quality data into coverage decisions, bundling claims into transparent pricing, and offering provider search functionality.
Enterprise SoftwareHealthtechInsurTechSan Francisco, US
PartnerMatt Miller· solo GP
Co-investors.406 Ventures3CC | Third Culture CapitalFlare Capital PartnersSemperVirens Venture CapitalDigitalis VenturesInitialized Capital
Josi Health provides online diagnostic evaluations for Autism Spectrum Disorder (ASD) and ADHD for children, teens, and adults, delivered by board-certified clinical psychologists.
Digital HealthHealthtechMental Health
PartnerMatt Miller· solo GP
Koda Health offers an online advance care planning platform that guides individuals through creating, sharing, and finalizing legally binding advance care plans according to their state's requirements.
Digital HealthHealthtechSaaS
PartnerMatt Miller· solo GP
MEDZOOMER operates an on-demand prescription delivery platform that connects patients with pharmacies to enable remote access to medications.
Digital HealthHealthtechLogistics & Supply ChainMedical DevicesTampa, US
Marvin Kloss(CEO/Founder)inMark Hammonds(Chief Technology Officer)inIlirian Ameti(Chief Financial Officer)inJustin Erro(VP of Growth)Richard Munassi(Executive Officer, Director)
BoardDavid Zinn(Director)in
PartnerMatt Miller· solo GP
Co-investorsBLH Venture Partners, LLCOcean Azul PartnersTechstarsMiami AngelsRevolution
Mirza is a software platform that automates benefits enrollment and eligibility verification for public assistance programs like Medicaid, SNAP, and childcare subsidies.
ConsumerGovTechHealthtech
Carly WarnerMel FaxonSiran Cao
PartnerMatt Miller· solo GP
Co-investors500 GlobalCartmell VenturesChaos VenturesEmmeline VenturesHalogen Ventures Management Company LlcResilienceVC+2 more
Nice Healthcare provides on-demand primary care and health services that come to patients' locations, aiming to reduce costs and improve accessibility compared to traditional clinic-based care.
Digital HealthEnterprise SoftwareHealthtechRoseville, US
Thompson Aderinkomi(Chief Executive Officer)Genevieve Swenson(Executive Officer, Director)
BoardAllison Santos(Director)Robert M. Greenglass(Director)Partha Sarathi Mishra(Director)
PartnerMatt Miller· solo GP
Co-investorsConductive VenturesGROOVE CAPITAL
OneImaging offers an employer-sponsored medical imaging benefit that connects members to a national network of 4,800+ accredited radiology centers with upfront pricing and care navigation support.
Digital HealthHealthtechMedical DevicesMiami, US
Elan Adler(Founder)
PartnerMatt Miller· solo GP
Co-investorsNecessary VenturesSemperVirens Venture CapitalXRCBalaji SrinivasanRedbud VCSixThirty Ventures+1 more
Orbit is developing a brain-computer interface and accompanying models that decode emotional states.
HealthtechLondon, GB
Akshat Sharma(CEO)inDipanshu Gandhi(CTO)in
PartnerMatt Miller· solo GP
Co-investorsEntrepreneur FirstStride Capital
OutcomesAI combines AI voice agents with licensed nurses to provide nurse triage, patient access, and post-acute care coordination.
AI & Machine LearningDigital HealthHealthtech
PartnerMatt Miller· solo GP
Pair Team develops an AI-enabled care coordination platform that connects people with healthcare providers and programs to deliver proactive, personalized care.
AI & Machine LearningDigital HealthHealthtechSan Francisco, US
Neil Batlivala(Founder)inCassie Choi(Founder)inCassandra Choi(Executive Officer, Director)
BoardJulian Eison(Director)in
PartnerMatt Miller· solo GP
Co-investorsCREATE HEALTH VENTURESKapor CapitalNext VenturesNTT Venture CapitalNVP CapitalY Combinator+7 more
Photon Health provides prescription routing infrastructure that lets patients choose a pharmacy based on real-time price, stock, and fulfillment options before a prescription is sent.
Digital HealthHealthtechSaaSNew York, US
Benjamin Otto Sipe(Executive Officer, Director, Promoter)Michael Rado(Director)
BoardNicholas Chirls(Director)in
PartnerMatt Miller· solo GP
Co-investorsFlare Capital PartnersFloating PointLong Journey VenturesNotation CapitalRitual CapitalHealthier Capital
Piction Health provides online dermatology care, letting patients submit information about a skin, hair, or nail concern and receive a personalized care plan reviewed by a dermatologist within 24-48 hours.
AI & Machine LearningDigital HealthHealthtech
Susan Conover(Co-founder)in
PartnerMatt Miller· solo GP
Co-investorsCarnrite VenturesFlare Capital PartnersGood Growth CapitalGutbrain VenturesHAWKTAILLaunchpad Venture Group+3 more
Pops is an AI-based health insurance assistant that users can have live conversations with 24/7 to get help understanding and selecting an insurance plan.
AI & Machine LearningDigital HealthInsurTech
Ryan RussellMike Russell
PartnerMatt Miller· solo GP
Co-investorsGROOVE CAPITAL
PromptWell offers an AI-powered member engagement platform that automates multi-channel, personalized outreach journeys for healthcare organizations such as health plans, payers, at-risk providers, and digital health companies.
AI & Machine LearningDigital HealthHealthtech
PartnerMatt Miller· solo GP
Radical Health develops technology in the medical and healthcare sector.
AI & Machine LearningDigital HealthHealthtechLondon, GB
Simone Korsgaard Jensen(Founder & Chief Executive Officer)Simone Jensen(CEO)in
PartnerMatt Miller· solo GP
Co-investorsEntrepreneur FirstKhosla VenturesProtagonistTranspose Platform Management
Reema Health provides behavioral health services combined with social needs navigation, using community care workers and a virtual care team to help members address unmet social needs such as food insecurity, housing, transportation, and loneliness.
Digital HealthHealthtechMental HealthMinneapolis, US
Matthew Swanson(Director)Amon Anderson(Director)Justin Ley(Executive Officer, Director)
BoardHelen Ciesielski(Director)Ellen Herlacher(Director)Mike Cunningham(Director)
PartnerMatt Miller· solo GP
Co-investorsDigitalis VenturesGROOVE CAPITALHC9 VenturesLRVHealthMaC Venture CapitalMatchstick Ventures+2 more
Rezilient Health provides primary and specialty care to employers and their families through a combination of in-person CloudClinics and telehealth services for a single flat fee.
Digital HealthEnterprise SoftwareHealthtechWellness & FitnessSt. Louis, US
Danish Nagda(Founder & CEO)Jeff Gamble(Founder & COO)Jeff Gamble, PhD(Founder)in
PartnerMatt Miller· solo GP
Co-investorsAcorn Pacific VenturesGOVO Venture PartnersMissouri Technology CorporationSeae VenturesTechstarsThe Council+1 more
Saile is a marketplace and credentialing platform for clinicians (physicians, CRNAs, NPs, and PAs) to find locums, telehealth, per diem, consulting, and clinical AI gigs directly from facilities without recruiter agencies.
Future of WorkHealthtechMarketplaces
PartnerMatt Miller· solo GP
Co-investorsMatchstick Ventures
Sophont develops multimodal foundation models for medicine that integrate data such as clinical history, labs, imaging, pathology, genomics, and wearables to model patient state, predict outcomes, and generate clinical hypotheses.
AI & Machine LearningBiotechHealthtech
Paulin
PartnerMatt Miller· solo GP
Co-investorsFactorial CapitalKindred VenturesTranspose Platform Management
Switchboard Health provides software that modernizes the specialty care referral process, using data sets, a virtual care network, and matching algorithms to connect patients with specialty care options.
AI & Machine LearningDigital HealthHealthtechSaaSBoise, US
Derek Baird(CEO)in
BoardArif Sorathia(Director)inBenjamin E. B. Britt(Director)inRyan Katz(Director)inJonathan Phillips(Director)
PartnerMatt Miller· solo GP
Co-investorsCapital ElevenFirst Trust Capital PartnersRoute 66 Ventures
Tembo Health provides care coordination and management services for seniors, particularly those with chronic conditions and dementia.
Digital HealthHealthtechLongevity
Anurag Gupta(CEO and founder)
PartnerMatt Miller· solo GP
Co-investorsCity LightEntrepreneurs Roundtable Accelerator (ERA)HDS CapitalMaccabee VenturesOceans VenturesPrimetime Partners+3 more
TrueClaim provides a modern insurance platform designed to reduce administrative errors and claims processing failures.
HealthtechInsurTechSan Francisco, US
Barbora Howell(Founder)inBobby Bayer(Founder)in
PartnerMatt Miller· solo GP
Co-investorsKAYAThe MBA FundY CombinatorOrange CollectiveRebel Fund
Vector Health is a revenue recovery platform for rural and critical access hospitals in the United States, finding funding patients qualify for through nonprofit copay assistance programs, insurance discovery and verification across 1,800+ payers, and government benefits like SSDI.
FintechHealthtechSaaSAustin, US
PartnerMatt Miller· solo GP
Co-investorsDorm RoomSilverton Partners
Volta provides billing, insurance verification, immunization compliance, and care navigation infrastructure for college and university campus health centers.
Digital HealthHealthtechSaaS
PartnerMatt Miller· solo GP
Co-investorsSuperCharger Ventures
Portfolio news
latest coverage across their companies
Bridge · wwaytv3.com · Aug 19, 2026
Pops · rock929rocks.com · Aug 12, 2026
Orbit · techtimes.com · Jul 31, 2026
Nice Healthcare · en.ilsole24ore.com · Jun 26, 2026
Josi Health · josihealth.com · May 26, 2026
Saile · finsmes.com · May 14, 2026
Piction Health · flarecapital.com · Apr 17, 2026
Reema · tcbmag.com · Dec 5, 2025
Frequently asked questions
- How many investments has Headwater Ventures made?
- Headwater Ventures has 40 tracked investments, including 3 dated in the last 24 months.
- What stage does Headwater Ventures invest at?
- Headwater Ventures invests at the Pre-Seed, Seed stages.
- What sectors does Headwater Ventures focus on?
- Headwater Ventures focuses on AI & Machine Learning, Data & Infrastructure, Digital Health, Enterprise Software, Healthtech, SaaS.
- Where is Headwater Ventures located?
- Headwater Ventures is headquartered in Minneapolis, US.
- Does Headwater Ventures lead rounds?
- Headwater Ventures typically participates in rounds rather than leading them.
- Who does Headwater Ventures co-invest with?
- Headwater Ventures most often shares deals with City Light, Y Combinator, Flare Capital Partners, among 91 tracked co-investors.
Co-investors · 8
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Matchstick Ventures is an early-stage venture capital firm that backs ambitious entrepreneurs located 'between the coasts,' investing capital, time, and resources at the pre-seed and seed stages.
Urban Innovation Fund is a seed-stage venture firm that invests in startups transforming large, regulated industries, providing capital, hands-on support, and regulatory insight.
SpringTime Ventures is a seed-stage venture firm investing in early-stage startups across healthcare, fintech/insurtech, and logistics/supply chain in the USA.
XRC Ventures (formerly XRC Labs) is an early-stage investment firm supporting startups, working with corporate partners, and running its own funds. The contact page invites startups to apply, service providers, corporate partners, and press inquiries.
GSR Ventures is a global early-stage technology investor backing companies building AI-enabled enterprise software, consumer platforms, and healthcare technology.
VU Venture Partners is a global early-stage technology venture capital fund investing across the world's largest market opportunities, operating with a large investment team and six vertical-focused practices.
Innova Memphis is a seed-stage investment firm that funds and mentors early-stage, high-growth companies, currently focused on AgTech and FarmTech ventures with strong intellectual property or competitive advantages.
Firms observed investing alongside Headwater Ventures, from public investor directories. Shared companies are the overlap with Headwater Ventures's recorded portfolio.
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