Headwater Ventures
Venture capitalActively deployingMinneapolis · Pre-Seed–Seed · 1 people tracked
Find your way into Headwater Ventures
1,348 people in our graph share verified history with the Headwater Ventures team — schools, employers, funds. One of them is your warm intro.
Investment thesis
Headwater invests in preseed and seed teams building software infrastructure and intelligence that make care administratively simpler, clinically safer, and financially clearer. It focuses on companies operating in the connective tissue between payers, providers, patient access, and operational workflows, favoring systems that can become repeatable defaults within regulated healthcare environments. The firm explicitly avoids pharma, biotech, medtech, and life sciences, concentrating instead on the software layer of health.
Source: firm website, verified Aug 7, 2026.
Team · 1 people
from the firm's website
What they invest in
from 40 of 41 portfolio companiesHealthtech ×36Digital Health ×29AI & Machine Learning ×18SaaS ×12Enterprise Software ×7InsurTech ×4Biotech ×2Fintech ×2
HQs:United States×26United Kingdom×2
Who they back
founder profiles across 27 portfolio companiesFounding team size:solo founder×162 founders×83 founders×3
Where their founders studiedfrom 31 founders with education data
Stanford University Graduate School of Business ×3Princeton University ×2Queen Elizabeth's School, Barnet ×2University of Cambridge ×2University of Minnesota ×2Washington University in St. Louis ×2
What their founders studiedfrom 33 founders with field-of-study data
Engineering ×9Computer Science ×7Business & Management ×5Economics ×5Life Sciences ×5Mathematics & Statistics ×4Medicine ×3Humanities ×2
Where their founders worked beforefrom 33 founders with career history
UCSF Medical Center ×3Beth Israel Deaconess Medical Center ×2Boston College ×2Brigham and Women's Hospital ×2Forward, Inc. ×2Ribbon ×2
Accelerator rootsportfolio companies that came through a program
3 founders hold a PhD · 8 hold an MBA (of 35 with degree data)
Investments · 41 tracked
founders shown can be your intro pathBy year:2025 · 42024 · 12022 · 22021 · 12019 · 210 dated
Affineon Health builds automation tools for healthcare providers and care teams, reducing administrative and tedious tasks so clinicians can focus on patient care.
AI & Machine LearningDigital HealthHealthtech
Ryan Van Wert(Physician Executive / Co-founder)inEvan(Executive (former COO Zus Health, CPO Codametrix, CPO Innovaccer))Tony(CTO)Dan(CFO & COO)Abid Siddiqui(Chief Operating Officer)in
PartnerMatt Miller· solo GP
Co-investorsAI FundBenhamou Global VenturesCity LightLoup VenturesSignal Peak Ventures
Andy is an AI-powered ambient scribing platform for home health agencies that automates clinical documentation, compliance checks, and medical coding.
AI & Machine LearningHealthtechSaaSSan Francisco, US
Tiantian Zha(Founder)in
PartnerMatt Miller· solo GP
Co-investorsf7 VenturesIA Seed VenturesInformed Ventures Advisors, LlcY Combinator
Automate Clinic is a multi-specialty medical group offering specialized, insurance-accepted care delivered remotely from patients' homes with continuity from a dedicated doctor.
Digital HealthHealthtech
PartnerMatt Miller· solo GP
Bridge provides billing and compliance infrastructure for telehealth and healthcare practices, handling insurance logistics and administrative workflows so providers can focus on patient care.
Digital HealthHealthtechInsurTechSaaS
Keaton Bedell(Founder)in
PartnerMatt Miller· solo GP
Credo Health is an AI-powered SaaS platform that helps physicians, medical service organizations, accountable care organizations, and health plans with patient diagnosis and treatment.
AI & Machine LearningDigital HealthSaaS
PartnerMatt Miller· solo GP
Co-investorsFCA Venture PartnersFirstMile VenturesHannah Grey VenturesService Provider CapitalSpringTime Ventures
Cured builds cloud-based enterprise software for healthcare organizations to modernize operations and improve patient and employee experiences.
AI & Machine LearningCloud ComputingDigital HealthEnterprise SoftwareHealthtechMarketing TechSan Francisco, US
Rohit(Co-Founder and Chief Customer Officer)inAshmer Aslam(Executive Officer, Director)inAndrew Sawyer(Executive Officer, Director)in
PartnerMatt Miller· solo GP
Co-investorsHigh Alpha
Defiant Health provides accelerated cancer care navigation, coordinating diagnostic testing, expedited specialist referrals, and care-plan reviews using the clinical standards of Dana-Farber Cancer Institute.
Digital HealthHealthtech
PartnerMatt Miller· solo GP
Co-investorsAmboy Street VenturesCity LightHannah Grey Ventures
Develop Health automates prior authorization and benefit verification for healthcare providers across EHRs and payers, while providing access intelligence to pharmaceutical manufacturers.
AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechMenlo Park, US
Mel van Londen(Co-Founder & CEO)inBenjamin Easton(Founder)in
PartnerMatt Miller· solo GP
Co-investorsAnalog VenturesMTECH CAPITALWingAfore CapitalSouth Park Commons
Dune Health offers a telehealth service that analyzes data from patients' wearable devices with AI to generate medical insights, which its doctors use to create and adjust personalized care plans.
AI & Machine LearningDigital HealthHealthtechSan Francisco, US
PartnerMatt Miller· solo GP
Co-investorsDiaspora Ventures
Menlo Park, US
Bobby Guelich(Founder)inMatthew Weinberg(Director)Liyuan Huang(Executive Officer)
PartnerMatt Miller· solo GP
Co-investorsAlleyCorpFloating PointNew Enterprise Associates (NEA)TMVAlley Robotics VenturesMax Ventures
Felt provides clinical infrastructure for product and engineering teams, offering an SDK, licensed clinical network, and compliance contracts to embed regulated healthcare care into applications.
Digital HealthHealthtechSaaS
PartnerMatt Miller· solo GP
Ferrum Health develops AI accountability solutions, though the specific products and customer base are not detailed on the company page.
AI & Machine LearningDigital HealthEnterprise SoftwareSunnyvale, US
Pelu Tran(Executive Officer, Director)in
BoardPatrick Steele(Director)inJaclyn Hester(Director)inKenneth Ko(Director)
PartnerMatt Miller· solo GP
Co-investorsBlumberg CapitalFoundryInformed Ventures Advisors, LlcUrban InnovationGSRSingTel Innov8 Pte Ltd.
Fincura AI automates insurance accounts receivable for healthcare practices, ingesting ERA 835 files, matching payments to claims, posting to practice management systems, and reconciling bank deposits.
AI & Machine LearningFintechHealthtech
Tim Schuermer(Founder (Commercial))in
PartnerMatt Miller· solo GP
Co-investorsPanache Ventures
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Gather Health provides primary care services with integrated social and home-based support for older adults in underserved communities.
Digital HealthHealthtech
PartnerMatt Miller· solo GP
Co-investorsHC9 VenturesKhosla VenturesMaverick Ventures
Glass Health provides an AI platform that assists clinicians in generating diagnostic hypotheses and developing treatment plans.
AI & Machine LearningHealthtechSaaSSan Francisco, US
Dereck Paul(Founder/CEO)inWilliam Hart(Founder/CTO)inBrett Plotzker(Executive Officer, Director)Jeremy Bluvol(Executive Officer)
BoardHari Sundram(Director)Jeffrey Parkinson(Director)
PartnerMatt Miller· solo GP
Co-investorsBreyer CapitalY Combinator645 VenturesInitialized Capital
Gratia Health offers an employee engagement platform for healthcare organizations that uses gamification, smart rewards, and real-time recognition to reinforce behaviors like shift reliability, safety, and patient experience.
HealthtechHR TechSaaS
PartnerMatt Miller· solo GP
Co-investors25MadisonCity LightJumpstart Capital
Helm Health provides benefit design and member engagement tools for health plans, incorporating cost and quality data into coverage decisions, bundling claims into transparent pricing, and offering provider search functionality.
Enterprise SoftwareHealthtechInsurTechSan Francisco, US
PartnerMatt Miller· solo GP
Co-investors.406 Ventures3CC | Third Culture CapitalFlare Capital PartnersSemperVirens Venture CapitalDigitalis VenturesInitialized Capital
Josi Health provides virtual ADHD and autism evaluations conducted by licensed psychologists, delivering comprehensive diagnostic reports accepted nationwide within weeks rather than months.
Digital HealthHealthtechMental Health
PartnerMatt Miller· solo GP
Koda Health provides a digital advance care planning platform that helps individuals create detailed advance care plans so their end-of-life and medical preferences are documented and honored.
Digital HealthHealthtechSaaS
PartnerMatt Miller· solo GP
MEDZOOMER operates an on-demand prescription delivery platform that connects patients with pharmacies to enable remote access to medications.
Digital HealthHealthtechLogistics & Supply ChainMedical DevicesTampa, US
Marvin Kloss(CEO/Founder)inMark Hammonds(Chief Technology Officer)inIlirian Ameti(Chief Financial Officer)inJustin Erro(VP of Growth)Richard Munassi(Executive Officer, Director)
BoardDavid Zinn(Director)in
PartnerMatt Miller· solo GP
Co-investorsBLH Venture Partners, LLCOcean Azul PartnersTechstarsMiami AngelsRevolution
Mirza is a software platform that automates benefits enrollment and eligibility verification for public assistance programs like Medicaid, SNAP, and childcare subsidies.
ConsumerGovTechHealthtech
Carly WarnerinMel FaxoninSiran Caoin
PartnerMatt Miller· solo GP
Co-investors500 GlobalCartmell VenturesChaos VenturesEmmeline VenturesHalogen Ventures Management Company LlcResilienceVC+2 more
Nice Healthcare provides on-demand primary care and health services that come to patients' locations, aiming to reduce costs and improve accessibility compared to traditional clinic-based care.
Digital HealthEnterprise SoftwareHealthtechRoseville, US
Thompson Aderinkomi(Co-Founder & CEO)inGenevieve Swenson(Co-Founder & COO)in
BoardAllison Santos(Co-Founder & Chief Business Officer)inRobert M. Greenglass(Director)Partha Sarathi Mishra(Director)in
PartnerMatt Miller· solo GP
Co-investorsConductive VenturesDNA CapitalGROOVE CAPITALIndie.vc
OneImaging coordinates medical imaging appointments across the United States, directing patients to appropriate scan sites based on need and price while connecting patients, providers, and payers.
Digital HealthHealthtechMedical DevicesMiami, US
Elan Adler(Founder)in
PartnerMatt Miller· solo GP
Co-investorsNecessary VenturesSemperVirens Venture CapitalXRCBalaji SrinivasanRedbud VCSixThirty Ventures+1 more
Orbit is developing a brain-computer interface and accompanying models that decode emotional states.
HealthtechLondon, GB
Akshat Sharma(CEO)inDipanshu Gandhi(CTO)in
PartnerMatt Miller· solo GP
Co-investorsEntrepreneur FirstStride Capital
OutcomesAI combines AI voice agents with licensed nurses to deliver scalable, high-quality care across hospitals, virtual care, and specialty programs.
AI & Machine LearningDigital HealthHealthtech
Kuldeep Singh Rajput(Founder)
PartnerMatt Miller· solo GP
Co-investorsSante Ventures
Pair Team develops an AI-enabled care coordination platform that connects people with healthcare providers and programs to deliver proactive, personalized care.
AI & Machine LearningDigital HealthHealthtechSan Francisco, US
Neil Batlivala(Founder)inCassie Choi(Founder)inCassandra Choi(Executive Officer, Director)in
BoardJulian Eison(Director)in
PartnerMatt Miller· solo GP
Co-investorsCREATE HEALTH VENTURESKapor CapitalNext VenturesNTT Venture CapitalNVP CapitalY Combinator+7 more
Photon Health provides prescription routing infrastructure that lets patients choose a pharmacy based on real-time price, stock, and fulfillment options before a prescription is sent.
Digital HealthHealthtechSaaSNew York, US
Benjamin Otto Sipe(Executive Officer, Director, Promoter)Michael Rado(Director)
BoardNicholas Chirls(Director)in
PartnerMatt Miller· solo GP
Co-investorsFlare Capital PartnersFloating PointLong Journey VenturesNotation CapitalRitual CapitalHealthier Capital
Piction Health provides online dermatology care, letting patients submit information about a skin, hair, or nail concern and receive a personalized care plan reviewed by a dermatologist within 24-48 hours.
AI & Machine LearningDigital HealthHealthtech
Susan Conover(Co-founder)in
PartnerMatt Miller· solo GP
Co-investorsCarnrite VenturesFlare Capital PartnersGood Growth CapitalGutbrain VenturesHAWKTAILLaunchpad Venture Group+4 more
Pops is an AI-based health insurance assistant that users can have live conversations with 24/7 to get help understanding and selecting an insurance plan.
AI & Machine LearningDigital HealthInsurTech
Ryan RussellMike Russell
PartnerMatt Miller· solo GP
Co-investorsGROOVE CAPITAL
PromptWell provides an AI-native engagement platform designed for healthcare organizations and health plans to personalize member communications and guide them toward appropriate care services.
AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechSaaS
Kaushik Viswanathan(Founder)inMike Lloyd(Founder)in
PartnerMatt Miller· solo GP
Radical Health develops technology in the medical and healthcare sector.
AI & Machine LearningDigital HealthHealthtechLondon, GB
Simone Jensen(CEO)in
PartnerMatt Miller· solo GP
Co-investorsEntrepreneur FirstKhosla VenturesProtagonistTranspose Platform Management
Reema Health provides a personalized, community-based care model that connects people to health care and social support services in their local communities.
Digital HealthHealthtechImpact & Social GoodMental HealthMinneapolis, US
Justin Ley(CEO)inMatt(Chief Product Officer)
BoardHelen Ciesielski(Director)inMatthew Swanson(Director)Ellen Herlacher(Director)inAmon Anderson(Director)
PartnerMatt Miller· solo GP
Co-investorsDigitalis VenturesGROOVE CAPITALHC9 VenturesLRVHealthMaC Venture CapitalMatchstick Ventures+2 more
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Rezilient Health provides primary and specialty care to employers and their families through a combination of in-person CloudClinics and telehealth services for a single flat fee.
Digital HealthEnterprise SoftwareHealthtechWellness & FitnessSt. Louis, US
Danish Nagda(Founder & CEO)inJeff Gamble(Founder & COO)inJeff Gamble, PhD(Founder)in
PartnerMatt Miller· solo GP
Co-investorsAcorn Pacific VenturesGOVO Venture PartnersMissouri Technology CorporationSeae VenturesTechstarsThe Council+2 more
Saile is a marketplace and credentialing platform for clinicians (physicians, CRNAs, NPs, and PAs) to find locums, telehealth, per diem, consulting, and clinical AI gigs directly from facilities without recruiter agencies.
Future of WorkHealthtechMarketplaces
PartnerMatt Miller· solo GP
Co-investorsMatchstick Ventures
Sophont develops multimodal foundation models for medicine that integrate data such as clinical history, labs, imaging, pathology, genomics, and wearables to model patient state, predict outcomes, and generate clinical hypotheses.
AI & Machine LearningBiotechHealthtech
Paulin
PartnerMatt Miller· solo GP
Co-investorsFactorial CapitalKindred VenturesTranspose Platform Management
Spora discovers and cultivates wild fungal strains from pristine ecosystems, processing them with proprietary biotechnology and nanotechnology to create mycelium-based products.
BiotechCircular EconomyDeep TechNew Materials
Co-investorsCapria VenturesHuman VenturesM13MaC Venture CapitalRefactor CapitalTechstars
Switchboard Health provides software that modernizes the specialty care referral process, using data sets, a virtual care network, and matching algorithms to connect patients with specialty care options.
AI & Machine LearningDigital HealthHealthtechSaaSBoise, US
Derek Baird(CEO)in
BoardArif Sorathia(Director)inBenjamin E. B. Britt(Director)inRyan Katz(Director)inJonathan Philips(Director)Jonathan Phillips(Director)
PartnerMatt Miller· solo GP
Co-investorsCapital ElevenFirst Trust Capital PartnersRoute 66 Ventures
Tembo Health provides care coordination and management services for seniors, particularly those with chronic conditions and dementia.
Digital HealthHealthtechLongevity
Anurag Gupta(CEO and founder)in
PartnerMatt Miller· solo GP
Co-investorsCity LightEntrepreneurs Roundtable Accelerator (ERA)HDS CapitalHilltop Venture PartnersMaccabee VenturesOceans Ventures+4 more
TrueClaim provides a modern insurance platform designed to reduce administrative errors and claims processing failures.
HealthtechInsurTechSan Francisco, US
Barbora Howell(Founder)inBobby Bayer(Founder)in
PartnerMatt Miller· solo GP
Co-investorsKAYAThe MBA FundY CombinatorOrange CollectiveRebel Fund
Vector Health helps rural hospitals identify uninsured and underinsured patients who qualify for financial assistance programs, using AI to unlock new revenue streams.
AI & Machine LearningDigital HealthFintechHealthtechSaaSAustin, US
Braden Fineberg(Co-Founder)inAnnie Klomhaus(CEO, Co-Founder)in
PartnerMatt Miller· solo GP
Co-investorsDorm RoomSilverton Partners
Volta Health builds health infrastructure specifically for college and university health centers, positioning itself as integrated plumbing rather than optional software.
Digital HealthEdTechHealthtechSaaS
PartnerMatt Miller· solo GP
Co-investorsSuperCharger Ventures
Portfolio news
latest coverage across their companies
Bridge · wwaytv3.com · Aug 19, 2026
Pops · rock929rocks.com · Aug 12, 2026
Orbit · techtimes.com · Jul 31, 2026
Nice Healthcare · en.ilsole24ore.com · Jun 26, 2026
Josi Health · josihealth.com · May 26, 2026
Saile · finsmes.com · May 14, 2026
Piction Health · flarecapital.com · Apr 17, 2026
Spora · trysignalbase.com · Feb 3, 2026
Frequently asked questions
- How many investments has Headwater Ventures made?
- Headwater Ventures has 41 tracked investments, including 4 dated in the last 24 months.
- What stage does Headwater Ventures invest at?
- Headwater Ventures invests at the Pre-Seed, Seed stages.
- What sectors does Headwater Ventures focus on?
- Headwater Ventures focuses on AI & Machine Learning, Data & Infrastructure, Digital Health, Enterprise Software, Healthtech, SaaS.
- Where is Headwater Ventures located?
- Headwater Ventures is headquartered in Minneapolis, US.
- Does Headwater Ventures lead rounds?
- Headwater Ventures typically participates in rounds rather than leading them.
- Who does Headwater Ventures co-invest with?
- Headwater Ventures most often shares deals with City Light, Y Combinator, Flare Capital Partners, among 95 tracked co-investors.
Co-investors · 8
Matchstick Ventures is an early-stage venture capital firm that backs ambitious entrepreneurs located 'between the coasts,' investing capital, time, and resources at the pre-seed and seed stages.
Urban Innovation Fund is a seed-stage venture firm that invests in startups transforming large, regulated industries, providing capital, hands-on support, and regulatory insight.
SpringTime Ventures is a seed-stage venture firm investing in early-stage startups across healthcare, fintech/insurtech, and logistics/supply chain in the USA.
XRC Ventures (formerly XRC Labs) is an early-stage investment firm supporting startups, working with corporate partners, and running its own funds. The contact page invites startups to apply, service providers, corporate partners, and press inquiries.
GSR Ventures is a global early-stage technology investor backing companies building AI-enabled enterprise software, consumer platforms, and healthcare technology.
VU Venture Partners is a global early-stage technology venture capital fund investing across the world's largest market opportunities, operating with a large investment team and six vertical-focused practices.
Innova Memphis is a seed-stage investment firm that funds and mentors early-stage, high-growth companies, currently focused on AgTech and FarmTech ventures with strong intellectual property or competitive advantages.
Firms observed investing alongside Headwater Ventures, from public investor directories. Shared companies are the overlap with Headwater Ventures's recorded portfolio.
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