Headwater Ventures
Venture capitalActively deployingMinneapolis · Pre-Seed–Seed · 1 people tracked
Investment thesis
Headwater invests in preseed and seed teams building the software infrastructure and intelligence that make care administratively simpler, clinically safer, and more financially transparent. It focuses on companies operating in the connective tissue between payers, providers, patient access, and operational workflows, favoring systems that can become repeatable defaults within regulated healthcare environments. The firm explicitly avoids pharma, biotech, med tech, and life sciences, concentrating solely on the software layer of health.
Source: firm website, verified Aug 7, 2026.
Team · 1 people
from the firm's website
What they invest in
from 20 of 40 portfolio companiesHealthtech ×18Digital Health ×14AI & Machine Learning ×8Enterprise Software ×6SaaS ×5InsurTech ×2B2B Marketplaces ×1Cloud Computing ×1
HQs:United States×16
Investments · 40 tracked
founders shown can be your intro path
Andy is an AI-powered ambient scribing platform for home health agencies that automates clinical documentation, compliance checks, and medical coding.
AI & Machine LearningHealthtechSaaSSan Francisco, US
Tiantian Zha(Founder)in
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
Credo Health is an AI-powered SaaS platform that helps physicians, medical service organizations, accountable care organizations, and health plans with patient diagnosis and treatment.
AI & Machine LearningDigital HealthSaaS
PartnerMatt Miller· solo GP
Cured builds cloud-based enterprise software for healthcare organizations to modernize operations and improve patient and employee experiences.
AI & Machine LearningCloud ComputingDigital HealthEnterprise SoftwareHealthtechMarketing TechSan Francisco, US
Rohit(Co-Founder and Chief Customer Officer)inAshmer Aslam(Executive Officer, Director)Andrew Sawyer(Executive Officer, Director)
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
Develop Health automates prior authorization and benefit verification for healthcare providers across EHRs and payers, while providing access intelligence to pharmaceutical manufacturers.
AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechMenlo Park, US
Mel van Londen(Co-Founder & CEO)Ben Easton(Co-Founder & CTO)
BoardSara Choi(Director)
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
Menlo Park, US
Matthew Weinberg(Director)Liyuan Huang(Executive Officer)
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
Ferrum Health develops AI accountability solutions, though the specific products and customer base are not detailed on the company page.
AI & Machine LearningDigital HealthEnterprise SoftwareSunnyvale, US
Pelu Tran(Executive Officer, Director)in
BoardPatrick Steele(Director)Jaclyn Hester(Director)Kenneth Ko(Director)
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
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Gather Health provides primary care services with integrated social and home-based support for older adults in underserved communities.
Digital HealthHealthtech<UNKNOWN>, US
PartnerMatt Miller· solo GP
Glass Health provides an AI platform that assists clinicians in generating diagnostic hypotheses and developing treatment plans.
AI & Machine LearningHealthtechSaaSSan Francisco, US
Dereck Paul(Founder/CEO)inWilliam Hart(Founder/CTO)inBrett Plotzker(Executive Officer, Director)Jeremy Bluvol(Executive Officer)Hari Sundram(Director)Jeffrey Parkinson(Director)
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
Helm Health provides benefit design and member engagement tools for health plans, incorporating cost and quality data into coverage decisions, bundling claims into transparent pricing, and offering provider search functionality.
Enterprise SoftwareHealthtechInsurTechSan Francisco, US
PartnerMatt Miller· solo GP
Josi Health provides online diagnostic evaluations for Autism Spectrum Disorder (ASD) and ADHD for children, teens, and adults, delivered by board-certified clinical psychologists.
Digital HealthHealthtechMental Health
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
MEDZOOMER operates an on-demand prescription delivery platform that connects patients with pharmacies to enable remote access to medications.
Digital HealthHealthtechLogistics & Supply ChainMedical DevicesTampa, US
Marvin Kloss(CEO/Founder)inMark Hammonds(Chief Technology Officer)inIlirian Ameti(Chief Financial Officer)inJustin Erro(VP of Growth)Richard Munassi(Executive Officer, Director)David Zinn(Director)
PartnerMatt Miller· solo GP
Mirza is a software platform that automates benefits enrollment and eligibility verification for public assistance programs like Medicaid, SNAP, and childcare subsidies.
GovTechHealthtech
PartnerMatt Miller· solo GP
Nice Healthcare provides on-demand primary care and health services that come to patients' locations, aiming to reduce costs and improve accessibility compared to traditional clinic-based care.
Digital HealthEnterprise SoftwareHealthtechRoseville, US
Allison Santos(Director)Robert M. Greenglass(Director)Genevieve Swenson(Executive Officer, Director)Thompson Aderinkomi(Chief Executive Officer)Partha Sarathi Mishra(Director)
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
Pair Team develops an AI-enabled care coordination platform that connects people with healthcare providers and programs to deliver proactive, personalized care.
AI & Machine LearningDigital HealthHealthtechSan Francisco, US
Neil Batlivala(Founder)inCassie Choi(Founder)inJulian Eison(Director)Cassandra Choi(Executive Officer, Director)
PartnerMatt Miller· solo GP
Photon Health operates a prescription marketplace that connects patients with pharmacies, displaying real-time pricing, availability, and fulfillment options before prescriptions are routed.
B2B MarketplacesHealthtechSaaSNew York, US
Benjamin Otto Sipe(Executive Officer, Director, Promoter)Michael Rado(Director)
BoardNicholas Chirls(Director)
PartnerMatt Miller· solo GP
Piction Health provides remote dermatological care, connecting patients with expert dermatologists for skin, hair, and nail concerns through online consultations and personalized treatment plans.
Digital HealthHealthtech
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
Radical Health develops technology in the medical and healthcare sector.
AI & Machine LearningDigital HealthHealthtech
Simone Korsgaard Jensen(Founder & Chief Executive Officer)
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
Rezilient Health provides primary and specialty care to employers and their families through a combination of in-person CloudClinics and telehealth services for a single flat fee.
Digital HealthEnterprise SoftwareHealthtechWellness & FitnessSt. Louis, US
Danish Nagda(Founder & CEO)Jeff Gamble(Founder & COO)
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
Switchboard Health provides workflow and data tools for health plans and providers to support specialty care navigation.
Digital HealthHealthtechSaaSBoise, US
Derek Baird(Executive Officer, Director)Arif Sorathia(Director)Benjamin E. B. Britt(Director)Jonathan Phillips(Director)Ryan Katz(Director)
PartnerMatt Miller· solo GP
Tembo Health provides care coordination and management services for seniors, particularly those with chronic conditions and dementia.
Digital HealthHealthtechLongevity
Anurag Gupta(CEO and founder)
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
PartnerMatt Miller· solo GP
Frequently asked questions
- What stage does Headwater Ventures invest at?
- Headwater Ventures invests at the Pre-Seed, Seed stages.
- What sectors does Headwater Ventures focus on?
- Headwater Ventures focuses on AI & Machine Learning, Data & Infrastructure, Digital Health, Enterprise Software, Healthtech, SaaS.
- Where is Headwater Ventures located?
- Headwater Ventures is headquartered in Minneapolis, US.
- Does Headwater Ventures lead rounds?
- Headwater Ventures typically participates in rounds rather than leading them.
Co-investors · 7
Urban Innovation Fund is a seed-stage venture firm that invests in startups transforming large, regulated industries, providing capital, hands-on support, and regulatory insight.
SpringTime Ventures is a seed-stage venture firm investing in early-stage startups across healthcare, fintech/insurtech, and logistics/supply chain in the USA.
XRC Ventures is an early-stage venture capital firm investing in startups transforming retail and commerce, spanning supply chain to storefront.
GSR Ventures is a global early-stage technology investor backing companies building AI-enabled enterprise software, consumer platforms, and healthcare technology.
Matchstick Ventures is an early-stage venture capital firm that backs ambitious entrepreneurs located 'between the coasts,' investing capital, time, and resources at the pre-seed and seed stages.
VU Venture Partners is a global early-stage technology venture capital fund investing across the world's largest market opportunities, operating with a large investment team and six vertical-focused practices.
Innova Memphis is a seed-stage investment firm that funds and mentors early-stage, high-growth companies, currently focused on AgTech and FarmTech ventures with strong intellectual property or competitive advantages.
Firms observed investing alongside Headwater Ventures, from public investor directories. Shared companies are the overlap with Headwater Ventures's recorded portfolio.
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