/Investor DB

645 Ventures — 2021 Investments

7 investments dated 2021 · listed companies and verified rows first · show all

Mandolinmandolin.cominJun 2021 · $12M

Mandolin provides AI agents that automate back-office workflows for specialty drug administration, including patient intake, benefits verification, prior authorizations, and revenue cycle management for infusion centers and clinical practices.

AI & Machine LearningEnterprise SoftwareHealthtechSan Francisco, US

Mary Kay Huse(Founder)Will Yin(Founder)inRohit Rustagi(Founder)inRobert Meitus(Founder)

BoardMike Fitzgerald(Director)inEric Tobias(Director)in

Board seatNnamdi Okike· per SEC Form D

Co-investorsGreylock PartnersOptum VenturesSignalFireSV AngelTimeless Partners VenturesFoundry+2 more

SkydropXskydropx.comin𝕏Series A · Oct 2021 · $20M

Skydropx offers a logistics management system that automates shipping for e-commerce and retail businesses in Mexico, including selecting, buying, and printing shipping labels, tracking shipments, estimating drop-off times, and handling returns.

E-commerceEnterprise SoftwareLogistics & Supply ChainMarketplacesSaaSMonterrey, MX

Tavo Zambrano(CEO)inArmando Solbes(Founder)inOscar Victorin(Founder)inArmando Solbes Argüello(Founder)inLuis Garza Sada(Executive Officer, Director)Arnoldo Collin(Executive Officer, Director)

Board seatAaron Holiday· per SEC Form D

Co-investorsCometaFJ LabsJam FundSierra VenturesSoma CapitalY Combinator+4 more

AptDecoaptdeco.comin𝕏Dec 2021

AptDeco operates a peer-to-peer managed marketplace for buying and selling quality used furniture, handling the full process including pickup, delivery, and secure payments.

Circular EconomyConsumerE-commerceLogistics & Supply ChainMarketplacesNew York City, US

Reham Fagiri(CEO)inKalam Dennis(Founder)inkalam dennis(Founder)inSam DostAmy Cooperstock(HR)Brad Pease(Director of Engineeing)

Co-investorsY CombinatorComcast VenturesFJ LabsForefront VentureGreat Oaks Venture CapitalHearstLab+9 more

Geniallygenially.comin𝕏Sep 2021 · $20M

Genially is a platform for creating interactive and animated content, with built-in AI tools for content generation.

AI & Machine LearningCreator EconomyEdTechSaaS

Luis García Díez(Founder)inChema Roldan(Founder)Juan Rubio(Founder)Luis Garcia(Founder)

Co-investorsAthos CapitalBrighteye VenturesCiveta InvestmentFJ LabsMarket One CapitalOwl Ventures+4 more

Shift5shift5.ioSeries A · Oct 2021 · $20M

Shift5 provides operational intelligence and cybersecurity solutions for military and commercial fleets across aviation, ground transportation, maritime, and rail sectors, helping operators detect threats and maintain system resilience in real-time.

CybersecurityDefense TechIoTArlington, US

Josh Lospinoso(Founder)inToby Magsig(President and Chief Executive Officer)Ronak Shah(Chief Technology Officer)in

Co-investorsBoeing HorizonX VenturesBooz Allen VenturesCenter15 CapitalInsight PartnersSavano Capital PartnersTeamworthy Ventures+3 more

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Negotiatus Corp.Launchable

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

645 Ventures — 2021 Investments | Fundraising Fox