/Investor DB

DIA

Venture capitalActively deploying

Cary · Pre-Seed–Series A · 8 people tracked

Also known as DENTAL INNOVATION ALLIANCE MANAGEMENT COMPANY, LP

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Investment thesis

DIA invests in the most promising early-stage dental technology companies, including SaaS platforms, devices, and therapeutics, aiming to accelerate dental and health innovation. Leveraging leadership backgrounds in some of the largest and most reputed Dental Support Organizations, the firm offers portfolio companies capital alongside strategic support, counsel, and direct access to a network representing more than 10,000 dental offices in the United States. DIA sources from an active pipeline that adds over 30 companies monthly via referrals from investors, dentists, startups, industry leaders, and other funds. The goal is to bring innovations to market faster and improve clinical outcomes, treatment efficiency, practice profitability, and margins.

Source: firm website, verified Sep 29, 2026.

Stage
Pre-Seed–Series A
HQ
Cary, US
Instruments
Equity
Founded
1884
Last 12 months
3 investments
Private fund assets
$35.3M
VC funds
1
Tracked investments
22
Unicorns
1

Team · 8 people

from the firm's website

What they invest in

from 20 of 22 portfolio companies

Healthtech ×15AI & Machine Learning ×10Medical Devices ×10Digital Health ×6SaaS ×6Hardware ×5Enterprise Software ×4Data & Infrastructure ×2

HQs:United States×11Belgium×1

Investments · 22 tracked

founders shown can be your intro path

By year:2026 · 32024 · 12023 · 12022 · 16 dated

Relurelu.aiinAug 2026✓ verified

Relu offers AI-powered segmentation and registration software for CBCT scans, digital impressions, and facial scans used in dental and oral surgery workflows.

AI & Machine LearningDigital HealthHealthtechMedical DevicesSaaSLeuven, BE

Co-investorsPMVKBC

Sjcbiosjcbio.com✓ verified

SJC Bio develops resorbable polymer-ceramic composite biomaterials for dental and craniofacial surgical applications, with its lead product OsseoCem providing immediate structural stability for bone grafting procedures.

BiotechHealthtechMedical DevicesNew MaterialsSan Diego, US

Robert K. Schultz, Ph.D.(Co-Founder & Chief Executive Officer)Steven Schneider, DDS, MBA(Co-Founder & Chief Dental Officer)

Altaaltatech.ioinAug 2026

Alta Resource Technologies develops engineered protein-based mineral separation technology to extract rare earth elements and critical minerals from mined ores, electronic waste, and processing byproducts.

CleantechDeep TechEnergyNew Materials

Nathan Ratledge, PhD(CEO)Matthew Lipscomb, PhD(CSO/President)

Co-investorsBaruch Future VenturesIn-Q-TelJuniperValor Equity PartnersAtreides ManagementDCVC (Data Collective)+8 more

Alta Smilesaltasmiles.cominJun 2024

Alta Smiles develops the V5x, a smartphone-based imaging device for dental and orthodontic providers to capture high-quality intra and extraoral photos in-office and enable remote patient monitoring during treatment.

AI & Machine LearningHardwareHealthtechMedical DevicesFort Washington, US

Gary D. Giegerich(Executive Officer, Director)in

BoardMichael Moeller(Director)

Co-investorsRun Ventures

Claritypeclaritype.cominJun 2022

Claritype builds an AI platform that delivers verifiable, fact-based answers from enterprise data using its GAR algorithm, connecting data across systems so non-technical users can explore and act on it without dashboards.

AI & Machine LearningData & InfrastructureEnterprise SoftwareMclean, US

Robert Giardina(Executive Officer, Director, Promoter)

BoardMurray Rode(Director)in

Co-investorsBow Capital

Cloud Dentistryclouddentistry.comin

Cloud Dentistry operates a self-serve online marketplace connecting background-checked dental professionals — hygienists, assistants, dentists, and office managers — with dental offices for temporary, part-time, and permanent work across the US.

HealthtechHR TechMarketplacesBoston, US

Trey Tepichin(Founder)inDarius SomekhianinRoberto Tepichin III(Executive Officer, Director)Clay Corman(Director)Paul Sims(Director)Reza Sanjar(Director)

Co-investorsHarvard Business Angels of ChicagoRock Creek Capital

Dentalbeedentalbee.ai

AI-powered clinical documentation platform that automatically generates notes, charts, and referrals from dental office conversations using ambient voice technology.

AI & Machine LearningDigital HealthHealthtechMedical DevicesSaaS

Dentousadentousa.comin

OralFitnessCheck is a chairside oral wellness test for dental practices that measures the aMMP-8 biomarker from a 30-second saliva swish and produces an Oral Fitness Score in about five minutes using the Oralyzer analyzer.

Digital HealthMedical DevicesWellness & Fitness

Enamel Pureenamelpure.cominMay 2023

Developer of the first hygienist-focused dental laser system

HealthtechWorcester, US

Charles Dresser(Executive Officer, Director)Nathan Monty(Executive Officer, Director)in

Endeavor Healthendeavorhealth.io

Lending aggregation for patient financing

Co-investorsTwine Ventures

Endeavorflowendeavorflow.comin

Endeavor builds financing software for healthcare providers and dental practices, enabling simpler patient conversations around treatment payment.

Enterprise SoftwareFintechHealthtechSaaS

Lightforcelf.coin

LightForce develops generative braces using artificial intelligence and 3D printing technology to create individualized orthodontic appliances tailored to each patient.

Advanced ManufacturingAI & Machine LearningHardwareHealthtechMedical DevicesBoston, US

Alfred Griffin, DMD, PhD(Chief Product Officer / Founder)Dr. Lou Shuman, DMD, CAGS(Co-founder)Erica Rogers(Chief Executive Officer)inAlfred Griffin(Founder)Lou Shuman(Founder)

PartnerKentucky Morrow· led

Co-investorsKleiner PerkinsAlly Bridge GroupAM VenturesMatrixMatter Venture PartnersOmega Venture Partners+3 more

Mashginmashgin.comin𝕏Series A

Mashgin develops automated checkout kiosks using computer vision and machine learning to instantly identify items without scanning or barcodes, serving retailers in stadiums, hospitality, hospitals, and foodservice venues.

AI & Machine LearningEnterprise SoftwareHardwareRetail TechSan Francisco, US

Abhinai Srivastava(Founder)inMukul Dhankhar(Founder)inMukul Dhankar(Founder)

Co-investorsClashmore VenturesFour CitiesHumba VenturesMatrixNew Enterprise Associates (NEA)Nimble Partners+12 more

Odneodne.coin

Odne develops OdneClean, an endodontic irrigation protocol and technology for root canal treatment in dentistry.

HardwareHealthtechMedical Devices

Co-investorsRevere PartnersZEISS Ventures

Pearlhellopearl.comin𝕏

Pearl develops FDA-cleared AI software that reads dental x-rays in real time, helping dentists detect cavities and other pathologies and show patients the evidence behind a diagnosis.

AI & Machine LearningHealthtechMedical DevicesWest Hollywood, US

Ophir Tanz(Founder and CEO)inCambron Carter(Co-Founder)inBen Plomion(Chief Operating Officer)inGad Sakin(Chief Technology Officer)in

Co-investorsCraft VenturesCrosscut VenturesGreen Meadow VenturesLeft Lane CapitalNeotribe VenturesSmash Capital+1 more

Perceptive Technologiesperceptive.ioin𝕏

Perceptive applies AI and robotics technology to dental practice, helping dentists increase patient capacity.

AI & Machine LearningHealthtechMedical DevicesRoboticsBoston, US

Chris Ciriello(Founder)inScott Phillips(Founder)inPhil Getto(CTO)inAlex Furleigh(Chief of Staff)in

Co-investorsAngel Physicians FundC3 VenturesNecessary VenturesRevere PartnersTSVCY Combinator+10 more

Smilessmiles.aiin𝕏Aug 2026

Smiles.ai (also branded Dezy) provides dental care including clear/invisible aligners, implants, and crowns through a network of clinics, using specialist orthodontists and at-home scanning.

ConsumerDigital HealthHealthtech

Jatin Kakrani(Founder)inHitesh Kakrani(Founder)in

Co-investorsAlpha Wave GlobalMBX CapitalRun Ventures

Sota Cloudsotacloud.comin𝕏

SOTA Cloud is a cloud-based imaging platform for dental practices that integrates imaging devices, practice management systems, and AI diagnostic tools into a single workflow.

AI & Machine LearningCloud ComputingDigital HealthHardwareHealthtechMedical Devices

Tuuthfairytuuthfairy.comin

TuuthFairy provides a GraphQL API that gives dental software platforms access to insurance data from hundreds of dental carriers, including plan maximums, deductibles, benefits, and frequency limitations.

Data & InfrastructureHealthtechSaaS

UptimeHealthuptimehealth.comin𝕏

Uptime Health provides operational tools and preventive maintenance plans to healthcare practices to reduce downtime and ensure regulatory compliance.

Enterprise SoftwareHealthtechSaaSBoston, US

William Olsen(Executive Officer, Director)Jinesh Patel(Executive Officer, Director)in

BoardJohn Huysmans(Director)

Co-investorsBantam GroupC2 VenturesCaduceus Capital PartnersKluz VenturesOverlineRevere Partners+8 more

Visio360visio360.ai

Visio360 provides analytics dashboards and reporting tools for multi-location healthcare or dental practice operators, covering metrics like daily production vs. collections, patient retention, labor cost vs. revenue, and missed appointments.

AI & Machine LearningDigital HealthSaaS

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Perceptive

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has DIA made?
DIA has 22 tracked investments, including 3 dated in the last 24 months.
What stage does DIA invest at?
DIA invests at the Pre-Seed, Seed, Series A stages.
What sectors does DIA focus on?
DIA focuses on Digital Health, Fintech, Healthtech, Medical Devices, SaaS.
Where is DIA located?
DIA is headquartered in Cary, US.
Who does DIA co-invest with?
DIA most often shares deals with Revere Partners, Crosscut Ventures, Kleiner Perkins, among 32 tracked co-investors.

Images

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