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Methuselah Foundation

Foundation

Springfield · Seed · 16 people tracked

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Investment thesis

The Methuselah Foundation pursues a mission-first approach to extending healthy human lifespan, framing its work around a falsifiable goal of making 90 the new 50 by 2030. Rather than measuring return on investment, it emphasizes 'return on mission' — reducing human suffering and hastening medical breakthroughs. The foundation identifies, tests, and funds high-leverage interventions that produce near-term progress and compounding long-term effects in aging research. It treats aging as both an engineering and cultural challenge, and backs early-stage people and projects, offering incubation and strategic services to help them advance longevity science.

Source: firm website, verified Oct 2, 2026.

Stage
Seed
HQ
Springfield, US
Instruments
Grants
Founded
2001
Tracked investments
11
Acquisitions
1

Team · 16 people

from the firm's website
Aubrey de Grey· Co-Founder

Co-founded the Methuselah Foundation in 2001; a researcher in the field of aging and longevity.

Dane Gobel· Co-Founder

Co-founded the Methuselah Foundation in 2001.

What they invest in

from 5 of 11 portfolio companies

Biotech ×5Deep Tech ×4Healthtech ×3Medical Devices ×3Digital Health ×1New Materials ×1

HQs:United States×5

Investments · 11 tracked

founders shown can be your intro path
Oncosenxoncosenx.cominJul 2021

OncoSenX is a late-stage pre-clinical cancer therapeutics company developing treatments that target solid tumors based on transcriptional activity.

BiotechDeep TechHealthtechSeattle, US

Matt Scholz(Executive Officer, Director)inJohn Lewis(Executive Officer, Director)inGary Hudson(Director)in

Co-investorsHelios CapitalMethuselah FundsChainFund CapitalInvesco

Repair Biotechnologiesrepairbiotechnologies.comin

Repair Biotechnologies develops the Cholesterol Degrading Platform, a therapeutic approach for treating conditions caused by localized accumulations of excess cholesterol.

BiotechHealthtechMedical DevicesSyracuse, US

Guilherme Cherman Perdigao de Oliveira(Executive Officer, Director)Reason("CEO's full legal name is ""Reason""")Anthony Matthew Chow(Director)

BoardKelsey Moody(Director)

Co-investorsLong GamequadraScope Venture FundThynk Capital

Viscient Biosciencesviscientbiosciences.com𝕏Aug 2021

Viscient Biosciences develops drugs by studying human 3D tissue models combined with multi-omics analysis to understand disease mechanisms.

BiotechDeep TechDigital HealthSan Diego, US

Keith Murphy(Executive Officer, Director)in

Co-investorsHarmonix FundMethuselah FundsThynk Capital

Volumetricvolumetricbio.com𝕏Seedacquired by 3D Systems

Volumetric Biotechnologies, acquired by 3D Systems in 2021, develops bioprinting materials and vascularized human tissue constructs.

BiotechDeep TechHealthtechMedical DevicesHouston, US

Jordan Miller(President)inBagrat Grigoryan(COO)in

Co-investorsGaingelsGoAhead VenturesHarmonix FundHelios CapitalJoyance PartnersJude Gomila+21 more

X-Therma Inc.x-therma.comin𝕏

X-Therma develops a proprietary peptoid-based technology that inhibits ice crystal formation to enable long-term sub-zero preservation and transport of cells, tissues, organs, and other biologics.

BiotechDeep TechMedical DevicesNew MaterialsRichmond, US

Xiaoxi Wei(Founder & CEO)inMark Kline(Executive Officer, Director)inJohannes Weggemann(Director)

Co-investorsAurum Venture PartnersDellin InvestmentsLIFTTMethuselah FundsPortfoliaVU Venture Partners+1 more

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Leucadia TherapeuticsMethuselah FundOisin TechnologiesOrganovoSilverstone SolutionsTurn Bio

Exits · 1

1 acquisitions

Volumetricacq. by 3D Systems

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has Methuselah Foundation made?
Methuselah Foundation has 11 tracked investments, 1 of which have exited.
What stage does Methuselah Foundation invest at?
Methuselah Foundation invests at the Seed stage.
What sectors does Methuselah Foundation focus on?
Methuselah Foundation focuses on Biotech, Healthtech, Impact & Social Good, Longevity, Medical Devices.
Where is Methuselah Foundation located?
Methuselah Foundation is headquartered in Springfield, US.
Who does Methuselah Foundation co-invest with?
Methuselah Foundation most often shares deals with Methuselah Funds, Harmonix Fund, Helios Capital, among 19 tracked co-investors.

Media · Podcasts & interviews

featuring the team

The Path to a 1000-Year Lifespan with Dr. Aubrey de Grey

InsideTracker · Aubrey de Grey

Progress with ending aging, with Aubrey de Grey

London Futurists · Aubrey de Grey

Dr. Aubrey de Grey, Ph.D. - President & Chief Science Officer ...

Progress, Potential, and Possibilities · Aubrey de Grey

Longevity Escape Velocity | Dr Aubrey de Grey Interview Series ...

Modern Healthspan · Aubrey de Grey

On Longevity Escape Velocity with Aubrey de Grey & Charles ...

Let’s Talk Longevity · Aubrey de Grey

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