San Francisco · Pre-Seed–Seed · 78 people tracked
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Investment thesis
IndieBio operated as SOSV's accelerator program providing pre-seed investment and on-site bio-lab facilities to scientists launching startups. Over a decade it backed 310 graduate companies that raised $3.6 billion, building a reputation across health and climate sectors including food, agriculture, industrial decarbonization, AI, therapeutics, and diagnostics. Its remit expanded beyond biology into all of deep tech, spanning chemistry, physics and AI, prompting a 2026 rebrand into SOSV NY and SOSV SF with the same teams, locations and facilities.
Source: firm website, verified Sep 27, 2026.
Team · 78 people
from the firm's website & curated & public directoriesFounder mafia
The IndieBio mafia →12 people who came through IndieBio went on to found or lead other companies.
What they invest in
from 18 of 24 portfolio companiesBiotech ×14Cleantech ×6New Materials ×6AgTech ×4AI & Machine Learning ×4Climate Tech ×3Deep Tech ×3FoodTech ×3
HQs:United States×10Switzerland×1Germany×1Israel×1
Investments · 24 tracked
founders shown can be your intro pathBy year:2026 · 42025 · 42024 · 22023 · 22022 · 32021 · 22020 · 12018 · 119 dated
Antarka develops a skin-permeable enzyme derived from Antarctic organisms that repairs UV-induced DNA damage, offered as a high-purity active ingredient for cosmetic brands to formulate into anti-aging creams, sunscreens, and repair serums.
BiotechConsumerDeep Tech
Betania Martínez(Founder)in
Co-investorsAIR CapitalGRIDXGS FuturesVox CapitalZentynel Frontier InvestmentsSOSV
BioAesthetics develops NACgraft, a cell-free, collagen-rich nipple-areolar complex graft that a surgeon applies so the patient's own cells integrate it into living nipple and areola tissue.
BiotechHealthtechMedical DevicesNew Materials
Juliana Blum(CEO & Director)Billy Heim(COO)in
Co-investorsFemHealth VenturesHemi Ventures, LlcJoyance PartnersNew Orleans Startup FundThe Launch PlaceBabel Ventures+1 more
BioEutectics develops eutectic chemical systems that serve industrial customers across multiple sectors, offering solutions ranging from direct solvent replacements to novel chemical capabilities.
BiotechCleantechFoodTechNew MaterialsTulsa, US
Federico JV Gomez(Founder)inMaria Fernanda Silva(Founder)in
Co-investorsAIR CapitalAtento CapitalGRIDXFen VenturesSOSVSyensqo Ventures
BiotechBelmont, US
Marie Causey(Executive Officer, Director)John Slattery(Executive Officer, Director)
Co-investorsAIFAUTISM IMPACT
Cellens develops a non-invasive, urine-based cancer diagnostics platform (Octosense) that uses nanoscale atomic-force imaging of single-cell biophysical markers combined with machine learning to detect cancer, with early data focused on bladder cancer detection.
AI & Machine LearningBiotechHealthtechMedical DevicesBoston, US
Phuong (Jean) Pham(CEO)in
BoardDeborah Zajac(Director)inLena Chaihorsky-Hering(Director)Mohan Iyer(Director)inJesse Salk(Director)in
Co-investorsCancer FundCreative Destruction Lab (CDL)SOSV
Diptera.ai uses computer vision and insect biology to control pest populations without pesticides, starting with mosquitoes.
AgTechAI & Machine LearningBiotechCleantechClimate TechDeep TechJerusalem, IL
Ariel Livne(Founder)in
Co-investorsfresh.fundSapir Venture PartnersTrust Ventures
Lingrove designs and manufactures Ekoa, a bio-based composite made from renewable flax and plant resins used as impact-resistant wall protection, wall coverings, ceilings, and millwork for hospitality, healthcare, senior living, and workplace interiors.
CleantechConstruction TechNew Materials
Joe Luttwak(Founder)
Co-investorsSnatched VenturesSoundboard Venture FundDiamond Edge VenturesSOSV
Fermeate develops a hardware module that connects to existing bioreactors and uses precisely timed light pulses to trigger genetic switches in production microorganisms, controlling yield, strain stability, and feedstock flexibility.
BiotechFoodTechHardwareSan Francisco, US
Ke Xu, PhD(Founder)inSaurabh Malani(Executive Officer, Director)Ke Xu(Executive Officer, Director)
BoardPo Bronson(Director)in
Co-investorsHeuristic Capital PartnersNewfund CapitalSOSV
FluoSphera develops in vitro human biology solutions for drug discovery, applying translational research to improve preclinical decision-making.
AI & Machine LearningBiotechDeep TechHealthtechGeneva, CH
Clélia Bourgoint(CEO, Chair & Co-Founder)inGregory Segala(CSO & Co-Founder)inAurélien Roux(Scientific Advisor & Co-Founder)
Co-investorsSICTICSoulmates VenturesSOSV
Helex is a biotech company whose team specializes in molecular biology, drug delivery, biomedical engineering, and nanotechnology research.
BiotechDigital Health
Rohini Kalvakuntla(Founder)in
Co-investorspi VenturesSOSV
Hoofprint Biome develops probiotics and natural enzymes based on microbiome engineering to reduce methane emissions from cattle while improving animal health and feed yield.
AgTechBiotechClimate TechCary, US
Kathryn Polkoff(Executive Officer, Director)inScott Collins(Founder)in
BoardRodolphe Barrangou(Director)in
Co-investorsGood Growth CapitalPonderosa VenturesSOSVAlexandria
iOrganBio builds CellForge, an AI- and automation-driven platform for engineering and manufacturing human cells and organoids.
Co-investorsCape Fear BioCapitalFirst Star VenturesHartmann CapitalAlix VenturesSOSV
Lingrove designs and manufactures Ekoa, a bio-based composite material made from flax and plant resins used as wall protection, wall coverings, ceilings, and millwork for hospitality, healthcare, and workplace interiors, as well as automotive interior applications.
CleantechConstruction TechNew MaterialsSan Rafael, US
Joseph Luttwak(Executive Officer, Director)in
BoardTalley Goodson(Director)Thomas Crow(Director)Stephen P. Welker(Director)
Co-investorsBoro CapitalCool Climate CollectiveDiamond Edge VenturesSeaX VenturesSoundboard Venture FundHelium-3 Ventures+2 more
Puna Bio develops microbial biostimulants, biofertilizers, and biofungicides for seed treatment based on extremophile bacteria collected from Argentina's Puna region, aimed at improving crop yields and regenerating degraded soils.
AgTechBiotechClimate TechSan Francisco, US
Carolina Belfiore(Executive Officer)inElisa Violeta Bertini(Executive Officer, Director)inFranco Martínez Levis(Executive Officer, Director)inMaría Eugenia Farías(Executive Officer)in
BoardDario Maffei(Director)Laurie Menoud(Director)in
Co-investorsAIR CapitalAt One VenturesCapria VenturesGLOCAL LatamGRIDXSOSV+4 more
Re-Fresh Global pioneers textile waste recycling solutions using biotechnology to transform discarded textiles into new, sustainable resources.
BiotechCircular EconomyCleantechNew MaterialsBerlin, DE
Urte Claudia Zahn(CEO)Revital Nadiv(COP & Co-Founder)in
Co-investorsSerpentine VenturesSie VenturesSOSV
AgTechAlbany, US
Siwen Deng(Executive Officer)Jessica Schwabach(Executive Officer)
Co-investorsClear Current CapitalEvolution VC PartnersNestleSOSV
Chilean food technology company that uses machine learning to reformulate animal-based foods such as mayonnaise, milk and burgers from plants.
Karim Pichara(Founder)inMatías Muchnick(Founder)Matías Muchnik(Founder)Pablo Zamora(Founder)
Co-investorsGeneral CatalystMAYA Capital VenturesSustainable Food VenturesThe CraftoryBezos ExpeditionsCleveland Avenue+5 more
Transition Metal Solutions applies microbial and biochemical methods to enhance copper extraction from low-grade ores, enabling more efficient recovery with reduced environmental impact for mining operations.
BiotechCleantechNew Materials
Co-investorsDolby Family VenturesJuniperNew Climate VenturesPossible Ventures
Upside Foods produces cultivated meat using cell-based technology.
BiotechFoodTechSan Francisco, US
Uma Valeti(Founder)inNicholas Genovese(Founder)Will Clem(Founder)
Co-investorsAlwyn CapitalBoxGroupCPT CapitalDentsu VenturesFifty YearsFuture Ventures+14 more
Wayfinder is a seed-stage venture capital fund that invests in early-stage founders building B2B companies across multiple industries including finance, enterprise software, AI, manufacturing, and robotics.
Advanced ManufacturingAI & Machine LearningCloud ComputingData & InfrastructureDeveloper ToolsEnterprise SoftwareHardwareSpace Tech
Tom Feldman(CTO and Co-Founder)Andy Lapsa(CEO and Co-Founder)Ant Wilson(CTO and Co-Founder)Paul Copplestone(CEO and Co-Founder)Yuri Sagalov(Founder and Managing Partner)
Co-investorsElementum VenturesInvariantes FundBoxOne VenturesConscience VCDivergent CapitalGENESIS CONSORTIUM+3 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
DisperseBioEndarisFinish Line BioXtelligence
Portfolio news
latest coverage across their companiesFluoSphera · finsmes.com · Jan 12, 2026
Diptera · ynetnews.com · Dec 22, 2025
iOrganBio · finsmes.com · Oct 30, 2025
Puna Bio · prnewswire.com · Jul 16, 2025
Hoofprint Biome · finsmes.com · May 2, 2025
Frequently asked questions
- How many investments has IndieBio made?
- IndieBio has 24 tracked investments, including 9 dated in the last 24 months.
- What stage does IndieBio invest at?
- IndieBio invests at the Pre-Seed, Seed stages.
- What is IndieBio's typical check size?
- IndieBio typically writes checks of $525K.
- What sectors does IndieBio focus on?
- IndieBio focuses on AgTech, AI & Machine Learning, Biotech, Cleantech, Climate Tech, Deep Tech, FoodTech, Hardware, Healthtech, New Materials, Sector Agnostic.
- Where is IndieBio located?
- IndieBio is headquartered in San Francisco, US.
- Does IndieBio lead rounds?
- IndieBio typically participates in rounds rather than leading them.
Media · Podcasts & interviews
featuring the teamFireside Chat with Po Bronson (IndieBio SOSV) – GRIDX SFO Demo Day
GRIDX · Po Bronson
#138: WTF (Alt-Protein Edition) With Indiebio's Po Bronson
The Spoon · Po Bronson
Arvind Gupta Discusses How IndieBio Turns Ideas Into Successful Companies
Neural Implant · Arvind Gupta
In Conversation With Arvind Gupta: Founder of IndieBio - World's Largest Biotech Accelerator
Biotecnika · Arvind Gupta
A Conversation with Po Bronson of IndieBio
Po Bronson · vimeo.com
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