Alexandra Cantley
InvestorManaging Partner at Polaris Partners · Board director at Cirrus Therapeutics, Inc. · Board director at TRex Holdings Inc. · Board director at Crossbow Therapeutics
New York, New York
Writes $300K – $2M checks · typically $500K
About
Alexandra Cantley is a managing partner at Polaris Partners, which she joined in 2019, working from the New York office with a focus on early-stage biotech and healthcare investments. Before Polaris, she was part of the initial research team at Inzen Therapeutics and previously held a research fellowship at Vertex Pharmaceuticals. She holds a PhD in Chemical Biology from Harvard University and completed her undergraduate studies at New York University.
Invests in
BiotechHealthtech
Board director at Cirrus Therapeutics, Inc.
Intro paths
In turn, Alexandra can intro founders to Cirrus Therapeutics, Inc.'s investors below.
Cirrus Therapeutics, Inc.'s investors · 1
Co-founders at Cirrus Therapeutics, Inc.
Board director at TRex Holdings Inc.
Intro paths
In turn, Alexandra can intro founders to TRex Holdings Inc.'s investors below.
TRex Holdings Inc.'s investors · 1
Board director at Crossbow Therapeutics
Intro paths
In turn, Alexandra can intro founders to Crossbow Therapeutics's investors below.
Experience
- Polaris PartnersPartnercurrent2021 — present
- Polaris PartnersPrincipalcurrent2019 — present
- Amplifire eLearningBoard Membercurrent2026 — present
- Cirrus TherapeuticsBoard Membercurrent2025 — present
- Crossbow Therapeutics, IncBoard Membercurrent2023 — present
- Auron Therapeutics, Inc.Board Membercurrent2022 — present
- TRexBioBoard Membercurrent2022 — present
- EpiBiologicsBoard Membercurrent2022 — present
- Capstan TherapeuticsBoard Observer2022 — 2025
- Inzen TherapeuticsScientist2017 — 2019New York City Metropolitan Area
- Vertex PharmaceuticalsVertex Fellow2016 — 2017
- Harvard UniversityGraduate Student2011 — 2016Harvard Medical School
- Columbia UniversityResearch technician2009 — 2011
Skills & more
From Alexandra's professional profile.
Deals · 8
Auron TherapeuticsBoard seat
via Polaris Partners · filed Dec 2025 · $42.3M raise
Crossbow TherapeuticsBoard seat
via Polaris Partners · filed Sep 2025 · $80M raise
Cirrus Therapeutics, Inc.Board seat
via Polaris Partners · filed Aug 2025 · $15.7M raise
TRex Holdings Inc.Board seat
via Polaris Partners · filed Nov 2024 · $85M raise
Epi BiologicsBoard seat
via Polaris Partners · filed Apr 2024 · $73M raise
SunBird Bio, Inc.Board seat
via Polaris Partners · filed May 2023 · $23.2M raise
Be Me HealthBoard seat
via Polaris Partners · filed Nov 2022 · $8.2M raise
PodimetricsBoard seat
via Polaris Partners · filed Apr 2022 · $60M raise
Attribution from SEC filings, press coverage, and firm rosters.
Other disclosed investments
Board seats
AmplifireCapstan TherapeuticsCirrus TherapeuticsEngine BioEpiBiologicsSunBird BioTRex Bio
Sources: the firm's website · SEC Form D filings.
Colleagues at Polaris Partners
Network9
Investors connected to Alexandra in public investor directories — a warm-intro map.
Frequently asked questions
- Who is Alexandra Cantley?
- Alexandra Cantley is a managing partner at Polaris Partners, which she joined in 2019, working from the New York office with a focus on early-stage biotech and healthcare investments. Before Polaris, she was part of the initial research team at Inzen Therapeutics and previously held a research fellowship at Vertex Pharmaceuticals. She holds a PhD in Chemical Biology from Harvard University and completed her undergraduate studies at New York University.
- Where does Alexandra Cantley work?
- Alexandra Cantley is Managing Partner at Polaris Partners and Board director at Cirrus Therapeutics, Inc. and Board director at TRex Holdings Inc. and Board director at Crossbow Therapeutics.
- What does Alexandra Cantley invest in?
- Alexandra Cantley invests in Biotech, Healthtech.
- What check size does Alexandra Cantley write?
- Alexandra Cantley typically writes checks of $300K – $2M.
- What boards does Alexandra Cantley sit on?
- Alexandra Cantley holds tracked board seats at Amplifire, Auron Therapeutics, Auron Therapeutics, Be Me Health, Capstan Therapeutics, Cirrus Therapeutics, Cirrus Therapeutics, Inc., Crossbow Therapeutics, Crossbow Therapeutics, Engine Bio.
- Where did Alexandra Cantley go to school?
- Alexandra Cantley studied at Harvard University (Doctor of Philosophy (PhD), Chemical Biology); New York University (Bachelor of Arts (B.A.)).
Same school
Also attended New York University385
+ 379 more
Shared employers
Also worked at Amplifire eLearning1
Also worked at TRexBio5
Also worked at Vertex Pharmaceuticals21
+ 15 more
Also worked at Harvard University293
+ 287 more












































