Houston · Pre-Seed–Seed · 4 people tracked
Also known as BIG VENTURES MANAGEMENT COMPANY, LLC
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Investment thesis
Cancer Focus Fund invests in oncology therapeutics — including immunotherapies, CAR-T and cell therapies, precision medicine and radiotherapeutics — that are approaching human clinical trials. Leveraging a unique relationship with MD Anderson Cancer Center, the fund sources oncology assets globally and uses a Scientific Advisory Committee of MD Anderson experts to identify candidates ready for trials. Its leadership then applies rigorous risk/reward analysis to select only a few drugs worthy of investment. The fund pairs decades of venture capital experience with MD Anderson's research and clinical-trial expertise, aiming to generate returns for investors while advancing breakthroughs for cancer patients.
Source: firm website, verified Sep 29, 2026.
Team · 4 people
from the firm's website & public directoriesWhat they invest in
from 7 of 11 portfolio companiesBiotech ×6Medical Devices ×3Healthtech ×2AgTech ×1Deep Tech ×1
HQs:United States×5United Kingdom×1Israel×1
Investments · 11 tracked
founders shown can be your intro pathBy year:2026 · 12024 · 12023 · 12020 · 12016 · 15 dated
Mereo BioPharma is a biopharmaceutical company publicly traded on Nasdaq under the ticker MREO.
BiotechHealthtechLondon, GB
John Richard(Head of Corporate Development and Co-Founder)inCharles Sermon(General Counsel and Co-Founder)Richard Jones(Chief Financial Officer)inJill Henrich(Senior Vice President)inDenise Scots-Knight(Chief Executive Officer)in
BoardDr. Deepa Pakianathan(Non-Executive Director)
Co-investorsPontifax Venture CapitalVivo CapitalWoodford Investment Management
Nectin Therapeutics develops novel monoclonal antibodies and antibody-drug-conjugates to treat difficult-to-treat cancers by targeting immune evasion mechanisms.
BiotechDeep TechMedical Devices
Co-investorsPeregrine VenturesIsrael Biotech Fund
ImmunoGenesis is a clinical-stage immuno-oncology biopharmaceutical company developing immune therapies for immune-excluded tumors, which resist standard PD-1 blockade.
BiotechHealthtechMedical DevicesDoylestown, US
Michael A. Curran(Director)inJennifer Barlow(Executive Officer, Director)Clifford Stocks(Director)James Barlow(Executive Officer, Director)Jeremy Barton(Executive Officer)Federica O'Brien(Executive Officer)
Co-investors3Spoke CapitalAdit Ventures Management, LlcAngel Physicians FundBioAdvanceService Provider CapitalTexas HALO Fund
Netherlands-based developer of fully synthetic immune therapies against cancer and persistent viral infections using a synthetic long peptide platform.
Co-investorsInvest-NLRegeneron Ventures
Uses proprietary technology to unmask cancer and recruit a targeted immune response.
Co-investorsaMoonPeregrine Ventures
March Bioscience is a cell therapy company assembling leading scientists and drug developers to advance cell therapy treatments.
BiotechMedical DevicesHouston, US
Sarah Hein(CEO, Co-Founder)inMaksim Mamonkin(Co-Founder, Chair Scientific Advisory Board)Malcolm Brenner(Co-founder)
BoardThomas Luby(Director)inPeter Olagunju(Director)inJoseph Petrosino(Director)
Co-investorsMission Biocapital4BIO CapitalCancer FundFitz Gate VenturesModi VenturesPortal Innovations+2 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Southeast Venture HoldingsEisbach BioMolecular ImagingNectin TherapeuticsStarget Pharma
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 1
1 IPOsMereo BioPharma GroupNASDAQ: MREO
Frequently asked questions
- How many investments has Cancer Focus made?
- Cancer Focus has 11 tracked investments, 1 of which have exited, including 2 dated in the last 24 months.
- What stage does Cancer Focus invest at?
- Cancer Focus invests at the Pre-Seed, Seed stages.
- What sectors does Cancer Focus focus on?
- Cancer Focus focuses on Biotech, Digital Health, Healthtech, Medical Devices.
- Where is Cancer Focus located?
- Cancer Focus is headquartered in Houston, US.
- Who does Cancer Focus co-invest with?
- Cancer Focus most often shares deals with aMoon, Adit Ventures Management, Llc, Cancer Fund, among 16 tracked co-investors.
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