Casdin Capital — Full Portfolio

Century Therapeutics develops allogeneic, iPSC-derived cell therapies for autoimmune diseases, including type 1 diabetes, and cancer.

BiotechHealthtechMedical DevicesPhiladelphia, US

Board seatEli Casdin· per SEC Form D · $160M raise · filed Mar 2021

Co-investorsVersant Ventures

Leyden Labs develops nasal sprays containing antibodies that target respiratory viruses such as influenza and COVID at the nasal mucosa to prevent initial infection and transmission.

BiotechDeep TechHealthtechLeiden, NL

Koenraad Wiedhaup(Founder & Chief Executive Officer)inRonald Brus(Founder & Chief Growth Officer)inJaap Goudsmit(Founding Scientist and Senior Advisor)inDinko Valerio(Founder and Chair of the Supervisory Board)Jintanat Ananworanich(Chief Medical Officer)Clarissa Koch(Chief Scientific Officer)

Co-investorsClavystBioF-Prime CapitalGV (Google Ventures)Bluebird VenturesEuropean Innovation Council FundEuropean Investment Bank+5 more

C2i Genomics develops TrueMRD, a cancer monitoring platform that combines whole-genome sequencing with AI algorithms to build personalized tumor signatures for detecting minimal residual disease (MRD).

AI & Machine LearningBiotechHealthtechNew York, US

Asaf Zviran(Founder)inEzra Sofer(Executive Officer, Director)

BoardAlex Parker(Director)Shaun Rodriguez(Director)in

Board seatEli Casdin· per SEC Form D

Co-investorsiGlobe PartnersLionBirdNFXSection 32

BiotechCambridge, US

Alexandra Glucksmann(Executive Officer, Director)Dominik Naczynski(Director)Chris Bowden(Director)Jake Simson(Director)Rosana Kapeller(Director)

BoardAbbie Celniker(Director)in

Board seatEli Casdin· per SEC Form D · $82.6M raise · filed Oct 2021

Co-investorsThird Rock Ventures

Genomatica (Geno) develops biotechnology processes to produce bio-based chemicals and materials—such as 1,4-butanediol (BDO), butylene glycol for cosmetics, and plant-based nylon—as alternatives to fossil-fuel-derived inputs.

BiotechCircular EconomyCleantechClimate TechNew MaterialsSan Diego, US

Christophe Schilling(Co-founder (former CEO))Bernhard Palsson(Co-founder)Thomas McDonald(Executive Officer)Carlos A. Cabrera(Executive Chairman)John G. Gugel(Chief Executive Officer)Tom McDonald(SVP, Finance & Chief Financial Officer)

Board seatEli Casdin· per SEC Form D · $119.1M raise · filed Aug 2021

Co-investorsVantagePoint Capital PartnersNovo Holdings

HealthtechNew York, US

David Klimstra(Executive Officer)Thomas Fuchs(Director)William Andrew Moye(Executive Officer, Director)Peter Hamilton(Executive Officer)Antoine Munfa(Director)Jim Beyer(Director)

Board seatEli Casdin· per SEC Form D · $39M raise · filed Mar 2023

Co-investorsCatalio Capital Management, LP

SomaLogic develops proteomics tools that help researchers measure protein function and study human biology across a range of scientific applications.

BiotechDeep TechHealthtechBoulder, US

Larry Gold(Director)inLarry Gold PhD(Founder)inDaniel Muehl(Executive Officer)Byron Hewett(Executive Officer, Director)

BoardCharles Lillis(Director)Youichi Yabuuchi(Director)

Board seatEli Casdin· per SEC Form D · $250M raise · filed Jan 2021

Co-investorsForesite CapitalKhosla Ventures

BiotechSan Francisco, US

Amy Duross(Executive Officer)Jason Bowman(Executive Officer)

BoardNigel Darby(Director)Rowan Chapman(Director)

Board seatEli Casdin· per SEC Form D · $75M raise · filed Nov 2020

Co-investorsCanaan PartnersThreshold Ventures

23andMe operates a research platform that collects genetic data from millions of users to advance genomic research and health discovery.

BiotechDigital HealthDirect to ConsumerHealthtechLongevityMountain View, US

Anne Wojcicki(Co-founder & CEO)inLinda Avey(Co-founder)Paul Cheung(Co-founder)Andrew Page(Executive Officer, Director)Kathy Hibbs(Executive Officer)

BoardEsther Dyson(Director)

Co-investorsAllied Venture PartnersCivilization Ventures Management, LlcEQUIAMG SquaredHouston Angel NetworkInvestX+12 more

Asimov collects real-world human activity data at scale from diverse environments to create annotated datasets for training robotics AI models.

Advanced ManufacturingAI & Machine LearningData & InfrastructureRoboticsSan Francisco, US

Lyem Ningthou(Founder)in

Co-investorsY CombinatorAME Cloud VenturesAndreessen Horowitz

Asimov develops a computer-aided design platform for genetic engineering, enabling designers to program living cells by applying abstraction, standardization, and modeling to biology.

AI & Machine LearningBiotechDeveloper ToolsBoston, US

Chris Voigt(Co-founder)inDoug Densmore(Co-founder)Alec Nielsen(Co-founder & CEO)inRaja Srinivas(Co-founder)in

Co-investorsAndreessen HorowitzDCVC (Data Collective)K5 GlobalKoch Disruptive TechnologiesPillar VCAME Cloud Ventures

Asimov builds a computer-aided design platform for genetic engineering and synthetic biology, enabling genetic designers to program living cells through automated circuit design and computational modeling.

AI & Machine LearningBiotechDeep TechBoston, US

Chris Voigt(Co-founder)Doug Densmore(Co-founder)Alec Nielsen(Co-founder & CEO)Raja Srinivas(Co-founder)in

Co-investorsAndreessen HorowitzWingAME Cloud Ventures

Boston, US

Jacob A. Donoghue, M.D., Ph.D.(Executive Officer, Director)Jarrett Revels(Executive Officer)Jacob A. Donoghue(Executive Officer, Director, Promoter)

BoardCaitlin Donovan(Director)Pavel Raifeld(Director)Naveen Rao(Director)

Co-investorsCatalio Capital Management, LPGeneral CatalystGV (Google Ventures)Iaso VenturesKicker VenturesIndicator Ventures+1 more

City Therapeutics develops RNAi-based medicines targeting rare, specialty, and prevalent diseases using engineered trigger molecules and precision delivery ligands.

BiotechMedical DevicesCambridge, US

Mark Keating, MD(Co-founder)Kotaro Nakanishi, PhD(Co-founder)Yukihide Tomari, PhD(Co-founder)Phillip Zamore, PhD(Co-founder)

Co-investorsAN Venture PartnersARCH Venture PartnersSofinnova VenturesFidelity InvestmentsInvusRock Springs Capital

BiotechCambridge, US

Chad A. Cowan(Executive Officer, Director)Leandro Vetcher(Executive Officer)Daniel Vasella(Director)Jim Glasheen(Executive Officer, Director)Neil White(Director)

BoardMartin Murphy(Director)

Co-investorsBain Capital Life SciencesVenrock Healthcare Capital Partners

Dyno Therapeutics develops artificial intelligence-powered genetic technologies for gene therapy, specifically engineering adeno-associated virus (AAV) capsids to improve gene delivery for treating genetic diseases.

AI & Machine LearningBiotechWatertown, US

Eric Kelsic(CEO & Cofounder)inSam Sinai(Vice President, Head of ML & Cofounder)inAdrian Veres(Chief Scientific Officer & Cofounder)George Church(Scientific Cofounder)Tomas Bjorklund(Scientific Co-founder)Alan Crane(Executive Chairman & Cofounder, Polaris Entrepreneur Partner)

Co-investorsAndreessen HorowitzCRV (Charles River Ventures)GENERAL INCEPTIONGV (Google Ventures)Lux CapitalObvious Ventures+2 more

Exo Therapeutics is a small molecule drug discovery company developing therapeutics through its ExoSight platform, which targets exosites—unique binding pockets on enzymes—to address previously undruggable diseases in oncology, inflammation, and other therapeutic areas.

BiotechDeep TechMedical Devices

David Liu, PhD(Founder)Alan Saghatelian, PhD(Co-Founder)David LiuAlan Saghetelian

Co-investorsNewpath PartnersCRV (Charles River Ventures)Nextech InvestRaptor GroupSamsara BioCapitalNovartis Venture Fund

Fabric Genomics provides an AI-based platform for next-generation sequencing (NGS) analysis, interpretation, and clinical reporting for rare disease, hereditary risk, and cancer testing.

AI & Machine LearningBiotechDigital HealthHealthtechMedical Devices

Martin Reese(Co-Founder, President, and CEO)Erwin Frise(Vice President of Technology and Data Science)

Co-investorsArtis VenturesForesite CapitalMighty Capital

Flare provides software infrastructure and operational support for emergency response teams in government and private sectors, enabling real-time resource management, location tracking, and coordination across multiple agencies to improve response times and effectiveness.

Enterprise SoftwareGovTechSaaSNairobi, KE

Co-investors4Di CapitalInovia CapitalAgent CapitalBase10 PartnersInvusNextech Invest+3 more

Flare is a layer 1 blockchain designed for data-intensive decentralized applications, providing enshrined data protocols and infrastructure for developers building with on-chain data.

Crypto & Web3Data & Infrastructure

Co-investorsDigital Currency GroupAgent CapitalBase10 PartnersInovia CapitalInvusNextech Invest+3 more

Flare develops AI-driven systems to manage essential workers—such as drivers, cleaners, security guards, and domestic workers—in emerging markets, vertically integrating its technology platform, worker staffing (via subsidiary Drive-Z), and customer implementation.

AI & Machine LearningFuture of WorkHR TechTokyo, JP

Kazuki Kamiya(CEO)Satoru Ichihara(COO)Shinya Hayashi(CSO)Hidefumi Iwaki(CFO)Tomohiro Sasaki(Executive Officer (Product Development))

Co-investorsANOBAKACARTA VENTURES, Inc.Spiral VenturesAgent CapitalBase10 PartnersInovia Capital+5 more

Hexagon Bio develops novel payload mechanisms for antibody-drug conjugates (ADCs) aimed at overcoming resistance to current cancer treatments and expanding ADC indications.

BiotechDeep TechHealthtechMenlo Park, US

Colin James Bell Harvey(Director)Brian T. Naughton(Director)Maureen E. Hillenmeyer(Executive Officer, Director)Maureen Hillenmeyer(CEO & Co-Founder)in

BoardAlex Kolich(Director)

Co-investorsB3 HoldingNextech InvestSoftBank Vision FundThe Column Group8VCTwo Sigma Ventures

insitro is a drug discovery and development company that uses machine learning and cellular data to identify therapeutic insights and accelerate the creation of new medicines.

AI & Machine LearningBiotechSouth San Francisco, US

Daphne Koller(CEO & Founder)inDuane Valz(General Counsel)Mary Rozenman(Chief Financial Officer)

BoardRobert Nelsen(Director)Vijay Pande(Director)in

Co-investorsAndreessen HorowitzARCH Venture PartnersForesite CapitalGV (Google Ventures)HOF CapitalSoftBank Vision Fund+5 more

Komodo integrates healthcare data across providers, health systems, care settings, and payers to deliver insights on disease incidence, treatment patterns, and health outcomes.

AI & Machine LearningData & InfrastructureHealthtechSan Francisco, US

Dr. Arif Nathoo(Co-Founder/Co-CEO)Web Sun(Co-Founder/Co-CEO)inArif Nathoo(Founder)in

Co-investorsAndreessen HorowitzCoatue ManagementFelicis VenturesICONIQMcKesson VenturesOak HC/FT+4 more

Lyra provides mental health care services through a network of evidence-based providers, combining clinical expertise with technology to deliver accessible, quality care for employers and health plans.

Digital HealthEnterprise SoftwareHealthtechHR TechMental HealthBurlingame, US

David Ebersman(Co-Founder & Chairman (CEO 2015–2025))inBob Kocher(Co-Founder and Board Member)inDena Bravata(Co-Founder & former Chief Medical Officer)Alethea Varra(Vice President of Clinical Care)Jennifer Schulz(Chief Executive Officer)Elaine Yang(Executive Officer)

Co-investorsAdditionBreyer CapitalCoatue ManagementDragoneer Investment GroupDurable Capital PartnersFidelity Investments+11 more

New York, US

Koda Mike Wang(Executive Officer, Director)

BoardTimothy Luke Sherwin(Director)

Co-investorsGreylock PartnersTenaya CapitalVenrock

Meiogenix develops a proprietary recombination technology that targets meiotic recombination to accelerate genetic gain and variety development in crops.

AgTechBiotechDeep Tech

Ricardo Garcia de Albain

Co-investorsGenoa VenturesKurma PartnersSofinnova Partners

Molecular Assemblies uses a Fully Enzymatic Synthesis (FES) technology to produce long, pure, and accurate synthetic DNA oligonucleotides, up to 400 bases, without post-synthesis purification.

BiotechDeep TechNew MaterialsSan Diego, US

J. William Efcavitch, Ph.D.(Treasurer and Chief Scientific Officer)Michael J. Kamdar(President, Chief Executive Officer and Secretary)

BoardDavid Hwang(Director)Larry Stambaugh(Chairman of the Board of Directors)John Nicols(Director)Todd Peterson(Director)

Co-investors11.2 CapitalDCVC (Data Collective)iSelect FundAlexandriaArgonautic VenturesKeshif Ventures+1 more

Multiply Labs builds robotic systems that automate biologics manufacturing for pharmaceutical companies.

Advanced ManufacturingBiotechDeep TechRoboticsSan Francisco, US

Fred Parietti(Founder/CEO)inAlice Melocchi(Founder)in

BoardShaun Rodriguez(Director)inMichael Doherty(Director)

Co-investorsFifty YearsGarage CapitalP101 VenturesStrange VenturesY CombinatorGraph Ventures+1 more

Octant is a therapeutics company that develops small molecule drugs to treat protein misfolding diseases.

AI & Machine LearningBiotechDeep TechMedical DevicesEmeryville, US

Sri Kosuri(Co-founder)inRamsey Homsany(Founder)in

Co-investorsAndreessen Horowitz+ND Capital8VCCarbon SiliconCatalio Capital Management, LPFifty Years+5 more

ONI develops the Nanoimager, an automated super-resolution imaging system.

BiotechDeep TechHardwareMedical DevicesOxford, GB

Co-investorsARCH Venture PartnersArtis VenturesFuture Planet CapitalOxford Technology ManagementVertical Venture Partners

Treeline develops therapeutics focused on oncology, leveraging insights from clinical practice and laboratory research.

AI & Machine LearningBiotechMedical DevicesWatertown, US

Joshua H. Bilenker(Executive Officer, Director, Promoter)Jeffrey Engelman(Executive Officer, Director, Promoter)inJosh Bilenker(Founder)in

BoardKristina Burow(Director)inAli Satvat(Director)David Schenkein(Director)in

Co-investorsAisling CapitalARCH Venture PartnersOrbiMedFidelity InvestmentsGV (Google Ventures)Rock Springs Capital+1 more

Ventus AI is an enterprise automation platform offering AI agents ("AI teammates") that operate inside existing systems—desktop apps, web portals, and legacy software—without API integrations to automate complex business workflows, handling MFA, CAPTCHAs, and phone calls.

AI & Machine LearningEnterprise SoftwareHealthtechCasa Grande

Maran Vedamanikam(CEO and Manager)

Co-investorsSamsung NextAndreessen HorowitzWndrCoBiotechnology Value FundFonds de solidarité FTQGV (Google Ventures)+4 more

BiotechSan Francisco, US

Kaz Ohno(Executive Officer)James Lim(Executive Officer)Brian S. Feth(Executive Officer, Director)

BoardSaeid Akhtari(Director)