Twelve Below
Venture capitalActively deployingNew York Β· Pre-SeedβSeed Β· 2 people tracked
Investment thesis
Twelve Below partners with ambitious founding teams at the pre-seed and seed stages, providing both capital and hands-on strategic support. The firm emphasizes founder-centric partnership, offering practical tactical guidance, network access, and accessible collaboration throughout the entrepreneurial journey. Their approach combines deep business understanding with genuine empathy for founder experiences.
Source: firm website, verified Jul 21, 2026.
Team Β· 2 people
from the firm's website
Partner who spent ten years at early-stage firms Primary and Canaan, focusing on breakthrough ideas from founders with deep market insights. Board experience includes Ro, Papa, K Health, Mirror, Italic, Osmind, and Mantra Health.
Partner with a decade of seed-stage investment experience at Lerer Hippeau and Collaborative, seeking breakthrough ideas from early-stage founders. Board positions span Allbirds, Step, Mirror, Leaflink, Teamshares, Transfix, Monument, Guideline, Crexi, Parsec, Hungryroot, OpenTrons, and Loyal.
What they invest in
from 9 of 31 portfolio companiesAI & Machine Learning Γ5SaaS Γ4Enterprise Software Γ2Fintech Γ2Healthtech Γ2HR Tech Γ2Biotech Γ1Cleantech Γ1
HQs:United StatesΓ2MexicoΓ1
Investments Β· 31 tracked
founders shown can be your intro pathCaladan Bio develops high-throughput benchtop bioreactor hardware and software for laboratory bioprocessing, enabling faster experimentation and lower costs for biotech R&D teams. The company integrates bioreactor equipment with AI-driven process modeling software to support strain optimization and scale-up workflows.
AI & Machine LearningBiotechHardware
Dispatch is a data orchestration platform that connects wealth technology software by automating client data collection and synchronization across advisory firm tech stacks. The company serves wealth advisory firms using multiple standalone software tools.
Data & InfrastructureEnterprise SoftwareFintechSaaS
Odyssey unlocks capital for the distributed energy sector in growth markets, enabling clean energy projects to be developed and financed faster. The company works with governments, donors, and concessional finance partners to scale renewable energy infrastructure across emerging markets.
CleantechClimate TechEnergyFintech
EmilyHenrikMaximeCaren
Pet's Table is a direct-to-consumer pet food delivery service in Mexico that provides fresh, natural dog food tailored to individual pets' nutritional needs. The company formulates recipes for dogs of different ages, sizes, and life stages, delivered via subscription directly to customers' homes.
ConsumerDirect to ConsumerFoodTech
Relay Commerce provides software solutions for e-commerce merchants to help them scale and manage their operations. The platform serves online retailers and merchants in the competitive e-commerce industry.
E-commerceRetail TechSaaS
Austin SimonGreg BursteinWill JonesTom Russell
Rondah AI provides an AI front desk solution for dental service organizations (DSOs) and practices, automating patient conversion and scheduling operations. The platform integrates with practice management systems to support both local practice routines and enterprise-wide standardization.
AI & Machine LearningHealthtechSaaSDover, US
Arya Health provides AI-powered digital agents that automate administrative and workforce management tasks for healthcare operators, including onboarding, scheduling, payroll, compliance, and performance management. The platform is designed to reduce manual workload on front-office staff and increase clinical workforce capacity and efficiency.
AI & Machine LearningHealthtechHR Tech
Voiceops is an AI platform that analyzes customer conversations across calls, email, SMS, and chat to generate structured business intelligence. The platform serves sales, customer experience, product, and leadership teams across organizations, automatically extracting insights on customer intent, buying signals, competitor mentions, and compliance risks.
AI & Machine LearningEnterprise SoftwareSaaSSales TechNew York City, US
Ethan Barhydt(Founder/CEO)in
Frequently asked questions
- What stage does Twelve Below invest at?
- Twelve Below invests at the Pre-Seed, Seed stages.
- What is Twelve Below's typical check size?
- Twelve Below typically writes checks of $1M β $3M.
- What sectors does Twelve Below focus on?
- Twelve Below focuses on Sector Agnostic.
- Where is Twelve Below located?
- Twelve Below is headquartered in New York, US.
- Does Twelve Below lead rounds?
- Yes, Twelve Below leads investment rounds.
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