🦊/Investors

Catalys Pacific

Venture capital

Tokyo · Seed–Series A · 26 people tracked

Also known as CATALYS PACIFIC, LLC

Find your way into Catalys Pacific

1,314 people in our graph share verified history with the Catalys Pacific team — schools, employers, funds. One of them is your warm intro.

James Detweilerunlockedknows Takeshi Takahashi · together at Morgan Stanley (overlapped)
×10knows the team · via Morgan Stanley
knows the team · via Waseda University
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Investment thesis

Catalys Pacific centers its investment and company-building strategy on transpacific partnerships, combining an extensive global network with on-the-ground local presence in both Japan and the United States. This dual presence enables differentiated deal sourcing and access to early-stage opportunities to found and build bespoke new biotech companies on both sides of the Pacific. The firm aims to maximize therapeutic impact for patients worldwide while generating attractive risk-adjusted returns for investors, focusing on creating innovation for patients through precision therapeutics and drug development.

Source: firm website, verified Sep 15, 2026.

Stage
Seed–Series A
HQ
Tokyo, JP
Instruments
Equity
Founded
2019
Private fund assets
$1.1B
VC funds
3
Tracked investments
11
IPOs
1
Acquisitions
1

Team · 26 people

from the firm's website & curated & public directories
Jogen Atone· Principal
Ariel Miura· Analyst
Hayato Urabe· Vice President

Vice President at Catalys Pacific; holds PhD and MPIA degrees.

Jonathan MacQuitty· Advisor

Advisor to Catalys Pacific; holds a PhD.

Masato Iwasaki· Advisor

Advisor to Catalys Pacific; holds a PhD.

Mitsuyuki “Mickey” Matsumoto· Operating Partner

Operating Partner at Catalys Pacific; holds a PhD.

Neal Fowler· Operating Partner

Operating Partner at Catalys Pacific; holds an MBA.

Nobuo Hanai· Advisor

Advisor to Catalys Pacific; holds a PhD.

Ryan Drant· Advisor

Founder mafia

4 people who came through Catalys Pacific went on to found or lead other companies.

What they invest in

from 8 of 11 portfolio companies

Biotech ×8Healthtech ×5Medical Devices ×2Digital Health ×1Fintech ×1

HQs:United States×6Japan×1

Investments · 11 tracked

founders shown can be your intro path

By year:2024 · 12022 · 12020 · 13 dated

Mineralys Therapeuticsmineralystx.comin𝕏NASDAQ: MLYSJun 2022

Mineralys Therapeutics is a clinical-stage pharmaceutical company developing lorundrostat, a treatment targeting dysregulated aldosterone.

BiotechHealthtechRadnor, US

Eric Warren(Chief Commercial Officer)inAlex Gold(Chief Medical Officer)inAdam Levy(Executive Officer)Alexander Asam(Director)

BoardOlivier Litzka(Director)in

Board seatTakeshi TakahashiBrian Taylor Slingsby· per SEC Form D

Co-investorsAndera PartnersSamsara BioCapitalSR One Capital ManagementYsios CapitalAdams Street PartnersBoulder Ventures+1 more

Arialysarialysrx.comin𝕏✓ verified

Arialys Therapeutics develops precision medicines designed to block pathogenic autoantibodies that target brain receptors such as the NMDA receptor, aiming to treat neuropsychiatric disorders driven by autoimmune disease.

BiotechHealthtechLa Jolla, US

Peter Flynn, Ph.D.(Executive Officer, Director)

BoardJay Lichter, Ph.D.(Director)Brian Slingsby, M.D., Ph.D., M.P.H.(Director)Ed Hurwitz(Director)inAshish Xavier, Ph.D.(Director)Tighe Reardon(Executive Officer)

Co-investorsAvalon BioVenturesMPM BioImpact

Crystalystxcrystalystx.comin𝕏✓ verified

Crystalys Therapeutics is a clinical-stage biopharmaceutical company developing targeted therapies for gout, a chronic metabolic disease caused by elevated uric acid.

BiotechHealthtechMedical DevicesSan Diego, US

James Mackay(President & Chief Executive Officer)inNihar Bhakta(Chief Medical Officer)inAshwin Ram(Chief Operating Officer)inDeAnne Reid(Chief Administrative Officer)in

Co-investorsNovo HoldingsAN Venture PartnersFrazier Life SciencesLightstone VenturesLongwood Fund

ヘパリスファーマ株式会社hepalys.com✓ verified

A company with expertise in developing pharmaceutical products through clinical trial phases (IND to NDA/BLA) and launching them for patients in Japan and Asia.

BiotechDigital HealthMedical DevicesTokyo, JP

Co-investorsDBJ CapitalNippon Venture Capital

HilleVaxhillevax.cominacquired by XOMA Royalty

XOMA Royalty is a biotech royalty aggregator that acquires the economic rights to future milestone and royalty payments tied to partnered pre-commercial clinical candidates, providing sellers with non-dilutive, non-recourse funding.

BiotechFintech

Co-investorsFrazier Life SciencesLightspeed Venture PartnersRA CapitalSamsara BioCapitalFrazier Healthcare Partners

Pathalyspathalys.comin𝕏Aug 2024 · $105M

Pathalys Pharma is a biotechnology company developing and improving therapeutic treatments for patients with chronic kidney disease.

BiotechHealthtechResearch Triangle Park, US

BT Slingsby(Co-Founder & Executive Chairman)in

Co-investorsAbingworthOrbiMedSamsara BioCapitalKB Investment

Phathom Pharmaceuticalsphathompharma.comin𝕏

Phathom Pharmaceuticals is a pharmaceutical company that develops and markets prescription treatments, including VOQUEZNA (vonoprazan) for gastrointestinal conditions, in the U.S. market.

BiotechHealthtech

Mr. Basta(CEO)

Co-investorsFrazier Life SciencesNew Enterprise Associates (NEA)

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Exalys TherapeuticsAculysKirilysMineralys

Exits · 2

1 IPOs · 1 acquisitions

Mineralys TherapeuticsNASDAQ: MLYSHilleVaxacq. by XOMA Royalty

Portfolio news

latest coverage across their companies

IPO stake values · per SEC filings

Value of this firm's stake in each portfolio company at its IPO price, from the prospectus principal-stockholder table.

CompanyOwnedIPO priceAt IPOStake value
Mineralys Therapeutics22.9%$16.00Feb 2023$143.1M

Source: SEC S-1 / 424B prospectus filings. Stake value = shares beneficially owned × the initial public offering price, as disclosed — a market value at IPO, not a return multiple (the firm's original cost is not disclosed).

Public market activity · per SEC filings

what is this? ⓘ

Files 13F institutional holdings reports · latest Aug 2026

From the firm's own SEC EDGAR filings — stakes and insider roles in public companies, typically portfolio companies after an IPO. Not a portfolio list published by the firm.

Frequently asked questions

How many investments has Catalys Pacific made?
Catalys Pacific has 11 tracked investments, 2 of which have exited.
What stage does Catalys Pacific invest at?
Catalys Pacific invests at the Seed, Series A stages.
What sectors does Catalys Pacific focus on?
Catalys Pacific focuses on Biotech, Digital Health, Healthtech, Medical Devices.
Where is Catalys Pacific located?
Catalys Pacific is headquartered in Tokyo, JP.
Who does Catalys Pacific co-invest with?
Catalys Pacific most often shares deals with Frazier Life Sciences, RA Capital, Samsara BioCapital, among 8 tracked co-investors.

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