Plains Ventures
Venture capitalOklahoma City · Seed–Series A · 3 people tracked
Also known as I2E MANAGEMENT COMPANY, INC.
Investment thesis
Plains Ventures focuses on Seed and Series A investments in companies located between the coasts, aiming to support entrepreneurs building outside traditional coastal tech hubs. Drawing on two decades of industry experience, the firm positions itself as a partner and guide throughout the company lifecycle, from pitch to exit. Beyond providing deployable capital, it leverages an extensive network of investors and subject matter experts to help founders set strategy, access additional funding, and build a foundation for growth across sectors such as software, life sciences, advanced materials, and manufacturing.
Source: firm website, verified Aug 3, 2026.
Team · 3 people
from public directories
What they invest in
from 35 of 39 portfolio companiesMedical Devices ×13Healthtech ×12Advanced Manufacturing ×7Biotech ×6Enterprise Software ×6AI & Machine Learning ×5Digital Health ×5SaaS ×5
HQs:United States×20
Investments · 39 tracked
founders shown can be your intro pathAccess Optics is an ISO 13485 certified contract design and manufacturing company specializing in medical device innovation and high-temperature probe production.
Advanced ManufacturingHardwareMedical DevicesBroken Arrow, US
William Paiva(Director)J.P. Lynch(Director)Matthew Gregoire(Executive Officer, Director)Sean Templemore-Finlayson(Director)
Game-based learning platform for K-6 students delivering gamified e-learning with analytics.
Boddle develops interactive learning software for students that adapts to individual learners and tracks their academic performance.
EdTechTulsa, US
Edna Martinson(Executive Officer)Clarence Tan(Executive Officer, Director)
BPEndo develops a medical device designed to prevent air and fluid incontinence during colonoscopy procedures, improving exam quality and patient safety for gastroenterologists and healthcare facilities.
HealthtechMedical DevicesNorman, US
Robert Holbrook(Founder & CEO)
Cadenza Bio develops small-molecule drugs for oral administration to treat demyelinating and inflammatory diseases.
BiotechFemTechMedical DevicesYukon, US
Carol Curtis, PhD(Chief Executive Officer, Founder)Elaine Hamm, PhD(Chief Operating Officer, Founder)John Katzenellenbogen, PhD(Scientific Founder)Seema Tiwari-Woodruff, PhD(Scientific Founder)Elaine Hamm(Executive Officer, Director)Tom Denison(Director)
Compound Foundry builds and scales direct-to-consumer home brands through in-house, on-shore manufacturing.
Advanced ManufacturingConsumerDirect to ConsumerMid-America, US
Digital Six Laboratories develops and manufactures SCADA and automation solutions for water and wastewater treatment facilities, offering on-site automation and remote monitoring with analytics to optimize operational efficiency.
Advanced ManufacturingEnterprise SoftwareIoTMidwest/Heartland USA, US
BiotechGermantown, US
Vera Mumm(Executive Officer)John Mumm(Executive Officer, Director)Pavel Khrimian(Executive Officer, Director)Lu Han(Director)Lucio Iannone(Director)Sally (Yuanheng) Wang(Director)
IV Ensure develops remote therapeutic monitoring technology for home infusion patients that tracks medication adherence and connects patients with care managers to support consistent treatment.
Digital HealthEnterprise SoftwareHealthtechMedical Devices
Mitchell Berenson(Founder)Debbie Meyer
A food company offering clean, simple, and healthy real food ingredients designed to be easy, enjoyable, and energizing.
KiZE makes clean protein energy bars with simple ingredients, sold through consumer retail channels.
ConsumerFoodTechImpact & Social GoodOklahoma City, US
Linear Health Sciences develops the Orchid Safety Release Valve, a tension-activated device for medical tubing that reduces IV catheter dislodgement and associated patient safety risks in hospitals.
HealthtechMedical DevicesOklahoma, US
Deon Miller(President & Chief Executive Officer)Renae Franz(Chief Operating Officer & Chief Commercial Officer)Casey Harness(Chief Administration Officer & Director of Operations)
Medefy is a mobile-first healthcare navigation platform that helps employers, brokers, TPAs, and public organizations guide members to appropriate care while reducing costs and improving health outcomes.
Enterprise SoftwareHealthtechSaaS
MATT SCOVIL(Executive Officer, Director)NATHAN GILCHRIST(Executive Officer, Director)James Barsness(Executive Officer)MONA JENKINS(Executive Officer)
BoardHeath Butler(Director)
Moleculera Biosciences is a precision medicine company that develops blood-based immune-mediated autoantibody testing panels and AI-driven diagnostic tools to identify immune dysfunction underlying chronic neuropsychiatric and cardiovascular disorders, as well as Alzheimer's disease.
AI & Machine LearningBiotechDigital HealthMedical Devices
Monscierge operates a SaaS platform that enables hospitality and healthcare organizations to deliver personalized content and communications across digital touchpoints.
HealthtechSaaSTravel & HospitalityOklahoma City, US
Marcus Robinson(Executive Officer, Director)
MS Pen Technologies develops molecular data analysis tools for use by researchers, surgeons, and clinicians at the point of care to improve patient outcomes.
Deep TechHealthtechMedical Devices
Livia Eberlin(Co-founder, CSO, Board Director)James Suliburk(Co-founder, CMO, Board Director)Justin Wiseman(CEO & Board Director)
Ordinal provides an AI assistant for 3-1-1 teams that gives municipal staff instant access to city-approved information to resolve resident inquiries faster and more accurately.
AI & Machine LearningEnterprise SoftwareGovTech
PhotoniCare develops OtoSight, an FDA-cleared optical coherence tomography device for non-invasive assessment and monitoring of middle ear infections in healthcare facilities.
Deep TechDigital HealthHealthtechMedical DevicesDurham, US
Ryan Shelton(CEO)Cary Vance(Executive Officer, Director)Gary Durack(Member of the Board of Directors)Stephen Boppart(CMO)
BoardPatrick Zeller(Director)Dale Grogan(Director)
Progentec develops diagnostic and digital health solutions for autoimmune disease detection and treatment, including biomarker tests and remote monitoring technologies for clinicians and patients.
BiotechDigital HealthMedical Devices
Mohan Purushothaman(CEO)Mohan Purushothaman, Ph.D.(President, Chairman, & CEO)Robert Saunders(Director)Sanjiv Sharma(Executive Officer, Director)
Rest provides IoT-based smoke detection sensors and monitoring services for hotels to enforce no-smoking policies and maintain air quality.
HealthtechIoT
Oklahoma City, US
Laura Fleet(Executive Officer, Director)David Fleet(Executive Officer, Director)
Simergent develops medical device systems for regulated healthcare markets, with expertise in peritoneal dialysis and infusion pump technologies.
BiotechHealthtechMedical DevicesChicago, US
Steve J. Lindo(Co-founder & CEO)Rick Pendergraft(Co-founder & Chief Technology Officer)Dr. James Sloand(Chief Medical Officer)Michael Rohleder(Manager)
Spiers New Technologies provides end-to-end EV battery management services including diagnostics, repair, refurbishment, recycling, storage, and logistics.
Advanced ManufacturingCleantechEnergyLogistics & Supply ChainOklahoma City, US
Dirk Spiers(Executive Officer, Director)James Joseph Greenberger(Executive Officer, Director)
Tailwind is a marketing platform that helps small businesses plan campaigns, create content, and distribute it across multiple social media channels.
Creator EconomyMarketing TechSaaS
Ten-Nine Technologies develops TENIX®, a nano-additive powder that improves lithium-ion battery performance and longevity by stabilizing cathode degradation.
CleantechEnergyNew MaterialsTulsa, US
Paige Johnson
Expert TA develops an online homework and tutoring platform for physics and STEM education, using AI-driven grading and tutoring interactions to help students learn.
AI & Machine LearningEdTechNorth Carolina, US
Jeremy Morton(CEO and Founder)in
Vault Ice manufactures and distributes large-format, ready-to-use premium craft cocktail ice for the food and beverage industry.
Advanced ManufacturingFoodTech
VesprSolar manufactures PV panel fasteners and rail systems designed for large-format solar modules to handle extreme weather and reduce installation time.
CleantechEnergyHardware
James Sewell(Director)Robert Sewell(Executive Officer, Director, Promoter)
WeGoLook operates an on-demand platform that connects trained professionals with businesses and consumers for real-time inspections of vehicles, properties, documents, and other assets.
B2B MarketplacesInsurTechMarketplaces
Wheeler Bio operates as a contract development and manufacturing organization (CDMO) for biomanufacturing, providing development and manufacturing expertise for biologics therapeutics.
Advanced ManufacturingAI & Machine LearningBiotechHealthtechMedical DevicesOklahoma, US
Patrick Lucy(Chief Executive Officer)inErrik Anderson(Director)M. Christian Kanady(Director)Keith McCormick(Executive Officer)Stephen Hamilton(Executive Officer)Yuk Chun Chiu(Executive Officer)
WS Robots manufactures autonomous mobile robots designed for aerospace manufacturing and maintenance operations, combining artificial intelligence and customizable end-effectors to automate precision tasks in production facilities.
Advanced ManufacturingAI & Machine LearningRobotics
Frequently asked questions
- What stage does Plains Ventures invest at?
- Plains Ventures invests at the Seed, Series A stages.
- What is Plains Ventures's typical check size?
- Plains Ventures typically writes checks of $250K – $1M.
- What sectors does Plains Ventures focus on?
- Plains Ventures focuses on Advanced Manufacturing, Biotech, Deep Tech, Medical Devices, New Materials, SaaS, Sector Agnostic.
- Where is Plains Ventures located?
- Plains Ventures is headquartered in Oklahoma City, US.
Media · Podcasts & interviews
featuring the teamRevolutionary Ideas Between The Coast with Justin Wilson, Plains Ventures - Strategic Growth Ep195
The Golding Group Business Growth Consulting · Justin Wilson
Images
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