Plains Ventures

Alkami is a digital banking software platform for financial institutions including community and regional banks and credit unions. The company provides modern digital banking user experience solutions to help banks serve customers in the digital-first environment.

Data & InfrastructureEnterprise SoftwareFintechMarketing TechSaaS

Mike Shootman(President and Chief Executive Officer)

An educational platform designed to help children develop their passion for learning and build a stronger future.

Boddle develops interactive learning software for students that adapts to individual learners and tracks their academic performance. The platform aims to make education engaging and accessible globally.

EdTech

BPEndo develops a medical device designed to prevent air and fluid incontinence during colonoscopy procedures, improving exam quality and patient safety for gastroenterologists and healthcare facilities.

HealthtechMedical DevicesNorman, US

Robert Holbrook(Founder & CEO)

A preclinical biotechnology company developing novel small-molecule drugs for treating demyelinating and inflammatory diseases.

Cadenza Bio develops small-molecule drugs for oral administration to treat demyelinating and inflammatory diseases. The company focuses on halting disease progression and promoting tissue repair in patients with debilitating conditions.

BiotechFemTechMedical Devices

Carol Curtis, PhD(Chief Executive Officer, Founder)Elaine Hamm, PhD(Chief Operating Officer, Founder)John Katzenellenbogen, PhD(Scientific Founder)Seema Tiwari-Woodruff, PhD(Scientific Founder)

Compound Foundry builds and scales direct-to-consumer home brands through in-house, on-shore manufacturing. The company operates as a holding company for a family of vertically-integrated consumer brands serving the home and lifestyle market in the USA.

Advanced ManufacturingConsumerDirect to ConsumerMid-America, US

Digital Six Laboratories develops and manufactures SCADA and automation solutions for water and wastewater treatment facilities, offering on-site automation and remote monitoring with analytics to optimize operational efficiency.

Advanced ManufacturingEnterprise SoftwareIoTMidwest/Heartland USA, US

A space/defense company developing 3D-printed hybrid rocket fuel to deliver safer, more affordable, and environmentally-friendly rocket solutions.

i2E is a nonprofit organization that supports early-stage founders and scalable companies in Oklahoma, providing structure, guidance, and connections to prepare them for growth and investment. The organization connects entrepreneurs to capital and investors while building a pipeline of investment-ready companies across the state.

Impact & Social GoodSector AgnosticOklahoma City, US

IV Ensure develops remote therapeutic monitoring technology for home infusion patients that tracks medication adherence and connects patients with care managers to support consistent treatment. The platform serves insurance organizations and healthcare providers seeking to reduce readmission rates and improve patient outcomes in chronic disease management.

Digital HealthEnterprise SoftwareHealthtechMedical Devices

Mitchell Berenson(Founder)Debbie Meyer

A food company offering clean, simple, and healthy real food ingredients designed to be easy, enjoyable, and energizing.

KiZE makes clean protein energy bars with simple ingredients, sold through consumer retail channels. The company is built around a social mission supporting individuals in recovery from addiction and homelessness, plus broader community aid efforts.

ConsumerFoodTechImpact & Social GoodOklahoma City, US

Linear Health Sciences develops the Orchid Safety Release Valve, a tension-activated device for medical tubing that reduces IV catheter dislodgement and associated patient safety risks in hospitals. The company operates in the medical device sector, addressing a preventable waste problem affecting U.S. healthcare systems.

HealthtechMedical DevicesOklahoma, US

Deon Miller(President & Chief Executive Officer)Renae Franz(Chief Operating Officer & Chief Commercial Officer)Casey Harness(Chief Administration Officer & Director of Operations)

Medefy is a mobile-first healthcare navigation platform that helps employers, brokers, TPAs, and public organizations guide members to appropriate care while reducing costs and improving health outcomes. The platform combines a mobile app with 24/7 live Care Guides to help users understand benefits, find in-network providers, and make informed healthcare decisions.

Enterprise SoftwareHealthtechSaaS

Moleculera Biosciences is a precision medicine company that develops blood-based immune-mediated autoantibody testing panels and AI-driven diagnostic tools to identify immune dysfunction underlying chronic neuropsychiatric and cardiovascular disorders, as well as Alzheimer's disease. The company operates an integrated platform combining diagnostic panels, a biorepository with bioinformatics, and a therapeutic target identification program.

AI & Machine LearningBiotechDigital HealthMedical Devices

Monscierge operates a SaaS platform that enables hospitality and healthcare organizations to deliver personalized content and communications across digital touchpoints. The platform helps brands improve customer loyalty, increase revenue, and enhance operational efficiency through an Experience Engine technology deployed across 45+ countries.

HealthtechSaaSTravel & Hospitality

MS Pen Technologies develops molecular data analysis tools for use by researchers, surgeons, and clinicians at the point of care to improve patient outcomes. The company operates in the medical device and surgical technology sector.

Deep TechHealthtechMedical Devices

Justin Wiseman(CEO & Board Director)Livia Eberlin(Co-founder, CSO, Board Director)James Suliburk(Co-founder, CMO, Board Director)

Encore Communications provides fiber internet, voice services, phone systems, and cabling solutions for businesses in the Tulsa area. The company builds and maintains a proprietary fiber optic network with local, hands-on support for small to large enterprises.

Cloud ComputingEnterprise SoftwareTulsa, US

Ordinal provides an AI assistant for 3-1-1 teams that gives municipal staff instant access to city-approved information to resolve resident inquiries faster and more accurately. The platform connects to existing city systems and documents, helping operators answer questions without transfers and supporting 24/7 resident access via chatbot, SMS, or voice.

AI & Machine LearningEnterprise SoftwareGovTech

PackMaxQ designs and manufactures thermal packaging solutions for cold chain logistics in healthcare and life sciences. The company specializes in preserving temperature-sensitive products including blood, biologics, medications, and medical devices during transit.

HealthtechLogistics & Supply ChainMedical Devices

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Custom Health operates a connected infrastructure combining pharmacy services, in-home monitoring technology, and pharmacist-led clinical care to support medication management at home. The company serves patients, caregivers, healthcare providers, and health plans.

Digital HealthHealthtechMedical Devices

PhotoniCare develops OtoSight, an FDA-cleared optical coherence tomography device for non-invasive assessment and monitoring of middle ear infections in healthcare facilities. The technology is designed for physicians treating ear-related conditions and offers improved accuracy over traditional otoscope methods.

Deep TechDigital HealthHealthtechMedical DevicesDurham, US

Ryan Shelton(CEO)

Progentec develops diagnostic and digital health solutions for autoimmune disease detection and treatment, including biomarker tests and remote monitoring technologies for clinicians and patients. The company focuses on improving health outcomes for the 25 million Americans living with autoimmune diseases.

BiotechDigital HealthMedical Devices

Mohan Purushothaman(CEO)Mohan Purushothaman, Ph.D.(President, Chairman, & CEO)

Rest provides IoT-based smoke detection sensors and monitoring services for hotels to enforce no-smoking policies and maintain air quality. The system alerts hotel staff to smoking violations, reducing room recovery costs and improving guest experience.

HealthtechIoT

Simergent develops medical device systems for regulated healthcare markets, with expertise in peritoneal dialysis and infusion pump technologies. The company is led by engineers with FDA clearance experience and clinical advisory from nephrologists.

HealthtechMedical DevicesChicago, US

Steve J. Lindo(Co-founder & CEO)Rick Pendergraft(Co-founder & Chief Technology Officer)Dr. James Sloand(Chief Medical Officer)

Spiers New Technologies provides end-to-end EV battery management services including diagnostics, repair, refurbishment, recycling, storage, and logistics. The company serves automotive businesses across the United States and internationally with a network of battery centers and technician locations.

CleantechEnergyLogistics & Supply ChainOklahoma City, US

Tailwind is a marketing platform that helps small businesses plan campaigns, create content, and distribute it across multiple social media channels. The platform serves e-commerce sellers, creators, local service providers, and marketing agencies through tools for analytics, scheduling, content design, and copy generation.

Creator EconomyMarketing TechSaaS

AlexDanny

Ten-Nine Technologies develops TENIX®, a nano-additive powder that improves lithium-ion battery performance and longevity by stabilizing cathode degradation. The company serves battery manufacturers and energy storage applications across electric vehicles and stationary storage systems.

CleantechEnergyNew MaterialsTulsa, US

Paige Johnson

Expert TA develops an online homework and tutoring platform for physics and STEM education, using AI-driven grading and tutoring interactions to help students learn. The platform serves educational institutions and their students.

AI & Machine LearningEdTechNorth Carolina, US

Jeremy Morton(CEO and Founder)

THG Energy provides a unified data platform that connects energy stakeholders including brokers, providers, businesses, institutions, industrial users, and governments to access and align on energy data.

Data & InfrastructureEnergySaaS

Vault Ice manufactures and distributes large-format, ready-to-use premium craft cocktail ice for the food and beverage industry. The company serves bartenders, restaurants, and cocktail establishments nationwide with high-quality ice products.

Advanced ManufacturingFoodTech

VesprSolar manufactures PV panel fasteners and rail systems designed for large-format solar modules to handle extreme weather and reduce installation time. The company serves solar installers and utility-scale solar developers in the renewable energy industry.

CleantechEnergyHardware

WeGoLook operates an on-demand platform that connects trained professionals with businesses and consumers for real-time inspections of vehicles, properties, documents, and other assets. The company serves insurance companies, property managers, consumers, and enterprises across multiple industries seeking verification and documentation services.

B2B MarketplacesInsurTechMarketplaces

Wheeler Bio is a contract development and manufacturing organization (CDMO) specializing in antibody-based therapeutics, offering integrated services including cell line development, process and analytical development, and regulatory support. The company operates U.S.-based manufacturing facilities and supports companies from discovery through commercial production.

Advanced ManufacturingBiotechMedical DevicesOklahoma, US

WS Robots manufactures autonomous mobile robots designed for aerospace manufacturing and maintenance operations, combining artificial intelligence and customizable end-effectors to automate precision tasks in production facilities.

Advanced ManufacturingAI & Machine LearningRobotics