Wireframe Ventures β Full Portfolio
50 tracked investments Β· listed companies and verified rows first
Palantir builds data integration and analysis platforms β Gotham for defence and government, Foundry for commercial operations β and deploys forward engineers inside customer organisations.
Palo Alto, US
Alexander Karp(Executive Officer, Director)Peter Thiel(Director)inStephen Cohen(Director)Nathan Gettings(Executive Officer, Director)Joe Lonsdale(Co-founder)in
BoardColin Anderson(Executive Officer)
Co-investors137 Ventures8VCA*Akkadian VenturesAllied Venture PartnersArtis Ventures+35 more
Bedrock Energy develops drilling technology and data algorithms for designing and installing geothermal borehole fields used for building heating and cooling.
CleantechClimate TechEnergyLos Angeles, US
Silviu Livescu(Executive Officer)inJoselyn Lai(Executive Officer, Director)inJoel Wishkovsky(Executive Officer, Director)
Board seatPaul StraubΒ· per SEC Form D
Co-investorsCantos VenturesEnergy Impact PartnersFirst Star VenturesTitanium VenturesToba CapitalClimate Capital+4 more
London
William Earle A'Hern(Director)Eliot Brooks(Chief Executive Officer, President, Secretary, Treasurer)Frederic Scott(Director)William Knapp(Director)
Board seatLily BernickerΒ· per SEC Form D Β· $5.5M raise Β· filed Jun 2024
San Francisco, US
Muffadal Ghadiali(Executive Officer, Director, Promoter)Naeem Zafar(Director)
BoardJulie Lein(Director)in
Board seatPaul StraubΒ· per SEC Form D
Co-investorsAcario InnovationBlackhorn VenturesUrban InnovationLemnos VC
Salient produces AI-powered subseasonal-to-seasonal weather and climate forecasts spanning one day to one year, using deep neural networks trained on ocean, land-surface, and climate data.
AI & Machine LearningClimate TechDeep TechFalmouth, US
Matthew Stein(Executive Officer, Director)Raymond Schmitt(Executive Officer, Director)inRay Schmitt(Co-founder)Eric Schmitt(Co-founder)inStephen Schmitt(Co-founder)in
Board seatPaul StraubΒ· per SEC Form D
Co-investorsBlindspot Ventures Management CoEndeavor8First Star VenturesMunich Re Ventures
San Francisco, US
Douglas Booms(Executive Officer)Dipender Saluja(Director)Greg Wasserman(Director)Timur Davis(Director)Ryan Harris(Executive Officer)Archan Rao(Executive Officer, Director)
Board seatPaul StraubΒ· per SEC Form D Β· $32M raise Β· filed Apr 2021
Co-investorsAmazon Alexa FundArcTern VenturesCongruent VenturesTechnology Impact
Applied Carbon develops technologies to regenerate soil and sequester atmospheric carbon for climate change mitigation and soil health improvement.
AgTechCleantechClimate Tech
Jason Aramburu(CEO + Co-Founder)inMorgan M. Williams(COO + Co-Founder)in
Co-investorsAutodesk FoundationCongruent VenturesS2G InvestmentsTO VCZag CapitalOverture Climate+1 more
Arise offered outpatient eating disorder services, which are being paused; the page now directs individuals and families to the Monte Nido team for evidence-based treatment and recovery support.
Digital HealthMental HealthWellness & Fitness
Co-investorsBluestein VenturesFTW VenturesVery Serious VenturesBBG VenturesInflect Health
GeneSight offers a pharmacogenomic (PGx) test that analyzes a patient's genetic variations from a cheek-swab DNA sample to inform healthcare providers about how a patient may respond to or metabolize medications used to treat depression, anxiety, ADHD, and other psychiatric conditions.
BiotechDigital HealthMental Health
Co-investorsAllos VenturesCincyTechCross Creek Advisors
Astronomer provides Astro, a platform for running Apache Airflow, the open-source data orchestration tool used by enterprises to manage AI, ML, and analytics pipelines at scale.
AI & Machine LearningCloud ComputingData & InfrastructureDeveloper ToolsCincinnati, US
Ry Walker(Founder)Viraj Parekh(Founder)inJoe Otto(Founder)inGreg NeiheiselTim BrunkTimothy Brunk(Executive Officer, Director)
Co-investors500 GlobalAngelPadBain Capital VenturesBosch VenturesCincyTechConnetic Ventures+10 more
Caladan Bio develops high-throughput benchtop bioreactor hardware and software for laboratory bioprocessing, enabling faster experimentation and lower costs for biotech R&D teams.
AI & Machine LearningBiotechHardwareNew York, US
Michael Kobida(Founder)inRob Jauquet(Founder)inMichael J. Kobida(Executive Officer, Director)Robert Jauquet(Executive Officer, Director)
Co-investorsCollaborative FundLerer HippeauRitual CapitalTwelve BelowFactorial Capital
CanopyClimate helps homeowners identify and install home energy technologies such as solar panels, heat pumps, induction stoves, EVs, and battery storage, generating a personalized savings guide with eligible incentives.
CleantechClimate TechEnergy
Co-investorsBuoyant Ventures Management, Llc
Cocoon develops low-carbon construction materials, including LoopCem, a supplementary cementitious material (SCM) made by valorizing electric arc furnace (EAF) steel slag to reduce concrete emissions.
Circular EconomyCleantechClimate TechNew MaterialsLondon, GB
Eliot Brooks(CEO)William Knapp(Founder)inDr. William Knapp(CSO)Freddie Scott(CTO)
Co-investorsBrick Mortar VenturesGigascale CapitalSOSVThe Venture Collective
DNAnexus operates a cloud platform for managing, analyzing, and collaborating on multiomic and clinical data, supporting bioinformatics workflows, AI/ML analytics, and cohort analysis.
AI & Machine LearningBiotechCloud ComputingData & InfrastructureMountain View, US
Andreas Sundquist(Executive Officer, Director)Richard Daly(Executive Officer, Director)George Asimenos, PhD(Chief Product Officer)in
BoardMICHAEL GOLDBERG(Director)GEOFF DUYK(Director)KRISHNA YESHWANT(Director)in
Co-investorsClaremont Creek VenturesForesite CapitalGV (Google Ventures)K9 VenturesUncork Capital
Endpoint Health develops therapeutics and therapy-guiding diagnostic tests personalized to each patient's biology for immune-driven critical and chronic illnesses such as sepsis, ARDS, rheumatoid arthritis and inflammatory bowel disease.
BiotechDigital HealthHealthtech
Co-investorsHumboldt
The U.S.
EnergyGovTech
Co-investorsFranklin TempletonPrelude VenturesSequoia CapitalT. Rowe Price
Enveda operates a drug discovery platform that reads and translates the chemistry of natural molecules to identify new medicines faster than industry averages.
AI & Machine LearningBiotechDeep Tech
Viswa Colluru, PhD(Founder)in
Co-investorsJAZZ Venture PartnersLux CapitalVillage Global
Full Harvest builds an agentic intelligence platform that orchestrates transactions and operations across the North American fresh produce supply chain, helping buyers and growers navigate climate volatility, labor shortages, and regulatory complexity.
AgTechAI & Machine LearningLogistics & Supply Chain
Co-investorsAstiaDoon Capitalmark vcPortfoliaRadicle GrowthRethink Impact+3 more
Geneticure offers a patented genetic test that uses a cheek-swab DNA sample, analyzing 17 genotypes across 11 genes to recommend personalized hypertension (blood pressure) treatment plans.
BiotechDigital HealthHealthtechMedical DevicesEden Prairie, US
Scott Snyder(Chief Executive Officer)inEric Snyder(Chief Operating Officer)inRyan Sprissler(Chief Scientific Officer)inTom Olson(Chief Clinical Officer)
Great Sky develops physics-based computational intelligence and AI systems built from foundational research.
AI & Machine LearningDeep TechHardwareBoulder, US
Jeffrey Shainline(Executive Officer, Director)inMark Wade(Director)in
BoardTom Biegala(Director)in
Co-investorsBison VenturesMatchstick VenturesMythos Ventures Management, LlcRange VCService Provider Capital
Gridware provides real-time monitoring and visibility of electrical grid conditions through sensors deployed on power lines, enabling utilities and line workers to detect and respond to problems faster.
Advanced ManufacturingClimate TechEnergyEnterprise SoftwareHardwareIoTSan Francisco, US
Tim Barat(Founder)inOmar B(Founder)inHall Chen(Co-Founder & CTO)in
Co-investorsAiSprouts VCAnorak VenturesConvective CapitalFifty YearsHAWKTAILLOWERCARBON+7 more
LevelTen Energy operates a platform that connects renewable energy developers with customers and market participants, facilitating project visibility and deal-making in the renewable energy sector.
B2B MarketplacesCleantechClimate TechEnergySaaSSeattle, US
Bryce Smith(Executive Officer, Director)inSmith Bryce(Executive Officer, Director)William Thomas(Executive Officer)
BoardDavid Cohen(Director)inKarly Wentz(Director)inGreg Lyons(Director)
Co-investorsAster CapitalB Capital GroupB4 CapitalConstellation Technology VenturesPrelude VenturesTechstars+1 more
Developing in-vivo CRISPR-based gene editing therapies.
Mammoth Bio develops technology to read and write the code of life, operating in the biotechnology sector.
BiotechDeep TechMedical DevicesBrisbane, US
Jennifer Doudna(Founder)inTrevor Martin(Co-founder, Chief Executive Officer)inJanice Chen(Co-founder, Chief Scientific Officer & President, Research)inLucas Harrington(Co-founder)inAshley Tehranchi(Executive Officer, Director)
BoardUrshit Parikh(Director)
Co-investors8VCBerkeley FrontierCALIFORNIA INNOVATIONDecheng CapitalForesite CapitalMayfield Fund+9 more
MycoWorks produces Reishi, a premium biomaterial made from Fine Mycelium, used as a sustainable leather alternative in furniture, design, and automotive products.
BiotechCircular EconomyNew MaterialsEmeryville, US
Philip Ross(Director)Michael Lindheim(Executive Officer)Matthew Scullin(Executive Officer, Director)
BoardKiersten Stead(Director)inThomas Grotkjaer(Director)
Co-investorsDCVC (Data Collective)Hemisphere Ventures LLC8VCAgFunderDCVC BioHumboldt+3 more
Near Space Labs provides high-resolution 7cm geospatial imagery captured from stratospheric altitudes, serving government, utilities, insurance, and environmental monitoring applications with frequent data refresh cycles and wide-scale coverage.
Climate TechData & InfrastructureSpace Tech
Rema Matevosyan(Founder & CEO)in
Co-investorsAt One VenturesBlackhorn VenturesBold Capital PartnersCrosslink CapitalDraper AssociatesGreen Egg Ventures+7 more
OpenInvest builds investment portfolio management software that customizes stock and bond holdings based on individual investor values and ethical preferences, while maintaining performance relative to standard market benchmarks.
FintechSan Francisco, US
Conor Murray(Founder/CEO)inPhillip Wei(Founder/CTO)in
Co-investorsAndreessen HorowitzY CombinatorAbstract Ventures
Passkey operates Locksmith, a computational platform that uses human genetics, biology, and pharmacology to identify synergistic drug combinations from approved and late-stage drugs, allowing existing assets to be repurposed for new indications.
AI & Machine LearningBiotechDeep Tech
Co-investorsBison VenturesBreakout Ventures
Pasture Bio develops a vaccine designed to disrupt methane-producing microbes in cattle's rumen, reducing enteric fermentation emissions while improving productivity and animal health.
AgTechBiotechClimate TechSan Francisco, US
Co-investorsCavallo VenturesGigascale Capital
Phytoform Labs develops GM-free genome editing tools and trait engineering technologies for crop improvement, with a focus on potato and tomato varieties.
AgTechAI & Machine LearningBiotechHarpenden, GB
William Pelton(Executive Officer, Director)Nicholas Kral(Director)Dhiraj Singh(Director)
Co-investorsBackedEniac VenturesFine Structures VenturesFTW VenturesManta Ray VenturesRefactor Capital+1 more
Recurrent builds software and data analytics tools to help consumers and dealerships transition to electric vehicles and optimize EV adoption.
Climate TechData & InfrastructureMobility & TransportationRetail TechSaaS
Scott Case(Founder)in
Co-investorsAscend Venture CapitalAutomotive Ventures MobilityEnerTech CapitalPrelude VenturesGeneral Catalyst
Regeneron is a biotechnology company that develops medicines ranging from biologics to genetic medicines to treat serious diseases across areas such as metabolic disease, ophthalmology, and rare disease.
BiotechHealthtechTarrytown, US
Co-investorsRidgeback CapitalSanderling VenturesvenBio Partners
Reverie Labs develops cancer treatments designed to cross the blood-brain barrier and treat tumors in the central nervous system.
AI & Machine LearningBiotechHealthtechBoston, US
Ankit Gupta(Founder/CTO)inConnor Duffy(Founder)inJonah Kallenbach(Founder)in
Co-investorsDorm RoomLifeforce CapitalRuvento Ventures Pte Ltd.Y CombinatorFirst Round CapitalNeo
New York, US
Kurt Breitenkamp(Executive Officer, Director)Orion Cohen(Executive Officer, Director)Ian Samuels(Director)Sarah Istel(Director)
Co-investorsSocial Starts
Video editing and collaboration platform.
Co-investorsRembrandt Venture PartnersScribble VenturesTransmedia Capital
Siren Optics builds material analysis systems that use cold atmospheric plasma and AI to perform real-time, non-destructive inspection of materials such as wafers, films, coatings, and battery components.
Advanced ManufacturingAI & Machine LearningDeep TechOakland, US
Jared O'Leary(Executive Officer, Director, Promoter)
BoardMatthew Blaine(Director)
Co-investorsInMotion VenturesUNION Labs VenturesVoyager Partners
Slack is an AI-powered communication platform that consolidates conversations, applications, and customer interactions in a single workspace for businesses.
Enterprise SoftwareFuture of WorkSaaSSan Francisco, US
Cal Henderson(Co-founder & CTO)inStewart Butterfield(Co-founder & CEO)in
Co-investors1991 VenturesAccelAcrew CapitalAglae VenturesAndreessen HorowitzAtlassian Ventures+32 more
Sora Schools provides an engaging, personalized learning experience built by educators, designers, and engineers.
EdTech
Co-investorsContraryHoneystone VenturesUnion Square Ventures (USV)Inspired CapitalNew Enterprise Associates (NEA)Peak State Ventures+3 more
Sora Fuel produces sustainable aviation fuel (SAF) and diesel using a proprietary closed-loop direct air capture and conversion process that draws carbon from air rather than biomass or industrial feedstocks.
CleantechClimate TechEnergyCambridge, US
Curtis BerlinguetteinGareth Ross(Executive Officer, Director)inCurtis Belinguete(Director)
BoardPatrick Sarver(Director)inMarc Tarpenning(Director)inMichael Kearney(Director)in
Co-investorsInnovation UBCInspired CapitalLeitmotifSpero VenturesThe Engine Ventures
SPAN develops smart electrical panels that provide real-time home energy monitoring and control, enabling homeowners to track and optimize energy consumption at the room and appliance level to reduce energy bills.
CleantechHardwareIoTSan Francisco, US
Arch Rao(Founder & CEO)
Co-investorsAngeleno GroupArcTern VenturesCollaborative FundCongruent VenturesDesigner FundEarth Foundry+15 more
SuperCircle is a technology and reverse logistics platform that helps retail brands launch trade-in programs and manage excess inventory to reduce textile waste.
Circular EconomyLogistics & Supply ChainSaaS
Chloe Marie Songer(Founder)inStuart Ahlum(Founder)in
Co-investorsFab Co-Creation Studio VenturesFoundryRareBreed VenturesStarting LineUlu VenturesBBG Ventures+2 more
Synop provides an all-in-one software platform for managing commercial electric vehicle fleets, charging stations, and distributed energy resources such as battery storage.
EnergyMobility & TransportationSaaSCarmel, US
Andrew Blejde(Executive Officer, Director)inGagan DhilloninGagandeep Dhillon(Executive Officer, Director)
Co-investorsBetter Ventures Central LlcCongruent VenturesObvious Ventures
Tembo builds a platform that serves as an operating layer for software engineering teams, providing secure execution, shared context, and workflow coordination for AI coding agents.
AI & Machine LearningCloud ComputingDeveloper ToolsEnterprise Software
Ry Walker(Founder)in
Co-investorsGreatPoint VenturesCincyTechCintrifuse CapitalGrand VenturesAscensionAviva Investors+4 more
Terraline offers a software-defined vehicle (SDV) platform that unifies vehicle control and telemetry, providing over-the-air updates, digital dashboards, and autonomy-ready APIs for intelligent machines and vehicles.
HardwareIoTMobility & TransportationMountain View, US
Co-investorsiNetworksManiv MobilityTrucks VC
ThinkBioscience develops small-molecule drugs aimed at historically difficult drug targets, using synthetic biology to identify novel mechanisms of biomolecular engagement.
BiotechDeep Tech
Co-investorsAV8 VenturesBuff Gold VenturesCU Healthcare Innovation FundAxial VC
Trove operates a platform for brand resale and recommerce, enabling iconic brands to sell returned and excess inventory through secondary markets.
AI & Machine LearningB2B MarketplacesCircular EconomyRetail TechBrisbane, US
ANDREW RUBEN(Director, Promoter)John Connolly(Founder)inGAYLE TAIT(Executive Officer, Director)
BoardGABRIEL KRA(Director)inBROOK PORTER(Director)inSHELLEY BRANSTEN(Director)
Co-investorsArcTern VenturesClaremont Creek VenturesCommerce VenturesDBL PartnersG2 Venture PartnersGlobal Brain+5 more
Tyba offers a software platform for battery energy storage developers, owners, and operators to model project configurations, generate AI-powered price forecasts, and optimize bidding and dispatch strategies across energy markets.
AI & Machine LearningCleantechEnergySan Francisco, US
Michael Baker(Founder)inTom Thunell(Founder)
Co-investorsEnergize CapitalLorimer VenturesVirta Ventures
Xcimer is a laser fusion energy company developing a low-cost, high-energy excimer laser architecture.
CleantechDeep TechEnergyDenver, US
Conner Galloway(Executive Officer, Director)Alexander Valys(Founder)ALEXANDER VALYS(Executive Officer, Director)
Co-investorsBreakthrough Energy VenturesGigascale CapitalLeitmotifLOWERCARBONLowercarbon CapitalPrelude Ventures+1 more
Xtelligent develops next-generation traffic signal control technology using control algorithms, real-time data streams, and machine learning to enable adaptive, multimodal, and cooperative management of signalized intersections for cities.
AI & Machine LearningGovTechMobility & Transportation
Co-investorsCongruent VenturesThird Sphere
Zivian Health builds compliance infrastructure and workforce management software for healthcare providers, nurses practitioners, and physician assistants operating across multiple states or remotely.
Digital HealthHealthtechSaaS
Rafid Fadul(Co-founder, Chief Medical Officer)Griffin Mulcahey(Co-founder, CEO)inJaclyn Miller(Chief Product Officer)Vanessa(Engineering Leader)
Co-investorsRally Ventures Management, LlcCrosslink CapitalNextView VenturesBlumberg CapitalGradient Ventures
Rows marked βSEC filingβ are inferred from directors named on the company's SEC Form D β public regulatory data, not a portfolio list published by the firm.


























