Where does Brian Smith work?

Brian Smith is Managing Director at S3 Ventures and Board director at Vahaticor and Board director at Spectrawave and Board director at Acessa Health.

What check size does Brian Smith write?

Brian Smith typically writes checks of $100K – $5M.

What boards does Brian Smith sit on?

Brian Smith holds tracked board seats at Acessa Health, Alkami Technology, ALKAMI TECHNOLOGY, INC., Alleviant Medical, Briggo, Crossroads Systems, Endovascular Engineering, Favor, Folia, Gravitant.

Where did Brian Smith go to school?

Brian Smith studied at Purdue University (MSEE, Electrical Engineering); University of Cincinnati (BSEE, Electrical Engineering).

Brian Smith

Investor

Managing Director at S3 Ventures · Board director at Vahaticor · Board director at Spectrawave · Board director at Acessa Health

Austin, Texas

Writes $100K – $5M checks · typically $1.5M

About

Brian R. Smith founded S3 Ventures and serves as its Managing Director. Earlier in his career he founded Crossroads Systems (Nasdaq: CRDS), taking it public in 1999 as Chairman and CEO after leading multiple financing rounds, and previously held product development roles in electrical engineering at IBM. He holds a BSEE from the University of Cincinnati and an MSEE from Purdue University.

Contact· self-published, not guessed

b•••@s3vc.comreveal

Invests in

Enterprise SoftwareFintechHealthtechMedical DevicesSaaS

Board director at Vahaticor

Intro paths

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In turn, Brian can intro founders to Vahaticor's investors below.

Vahaticor's investors · 2

Intuitive VenturesSunnyvale · since 2025 S3 VenturesAustin · $500K – $15M checks · since 2025

Board director at Spectrawave

Intro paths

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In turn, Brian can intro founders to Spectrawave's investors below.

Spectrawave's investors · 5

Deerfield Management CompanyNew York · since 2019 Johnson & Johnson Innovation – JJDCNew Brunswick · since 2019 Lumira VenturesToronto · $1M – $10M checks · since 2024 S3 VenturesAustin · $500K – $15M checks · since 2019 SV Health InvestorsBoston · $1M – $20M checks · since 2024

Co-founders at Spectrawave

Eman NamatiPresident & CEO

Guillermo TearneyFounder; Professor of Pathology, Massachusetts General Hospital

Gregg StoneFounder; Professor of Medicine, Mount Sinai Heart Health System

James MullerFounder; Cardiologist, Brigham and Women's Hospital

Jeffrey O'DonnellFounder; Managing General Partner, Runway Healthcare

Board director at Acessa Health

Intro paths

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In turn, Brian can intro founders to Acessa Health's investors below.

Acessa Health's investors · 1

S3 VenturesAustin · $500K – $15M checks · since 2017

Experience

S3 VenturesManaging Directorcurrent2005 — presentAustin, Texas Metropolitan Area
MaxQ MedicalBoard of Directorscurrent2026 — presentSan Jose, California, United States
RapidPulse, Inc.Board of Directorscurrent2026 — presentMiami, Florida, United States
Advanced NanoTherapiesBoard of Directorscurrent2026 — present
Reparo SurgicalBoard of Directorscurrent2025 — presentAustin, Texas, United States
VentureMed Inc.Board of Directorscurrent2025 — presentMinneapolis, Minnesota, United States
VahatiCor IncBoard of Directorscurrent2025 — presentSan Jose, California, United States
Folia Health: The Home-Reported Outcomes CompanyBoard of Directorscurrent2025 — present
Versa VascularBoard of Directorscurrent2025 — presentSanta Cruz, California, United States
Endovascular EngineeringBoard of Directorscurrent2025 — presentPalo Alto, California, United States
LiquibaseBoard of Directorscurrent2016 — presentAustin, Texas Metropolitan Area
VUV Analytics, Inc.Board of Directorscurrent2014 — presentAustin, Texas Metropolitan Area
Alkami TechnologyBoard of Directorscurrent2011 — presentDallas-Fort Worth Metroplex
SpectraWAVE, Inc.Board of Directors2024 — 2026Boston, Massachusetts, United States
SaranasBoard of Directors2021 — 2024Houston, Texas, United States
Tango Health, Inc.Board of Directors2010 — 2021Austin, Texas Metropolitan Area
Acessa Health Inc. - Acessa ProcedureBoard Of Directors2017 — 2020Austin, Texas Metropolitan Area
Liveoak Technologies, a DocuSign CompanyInvestor2017 — 2020Austin, Texas, United States
Briggo CoffeeBoard Of Directors2017 — 2020Austin, Texas Metropolitan Area
TVA Medical, Inc.Board of Directors2013 — 2018Austin, Texas Metropolitan Area
Packet DesignBoard of Directors2013 — 2018
FavorBoard of Directors2015 — 2018Austin, Texas Metropolitan Area
InvodoBoard of Directors2008 — 2018Austin, Texas Metropolitan Area
KimbiaBoard of Directors2011 — 2018Austin, Texas Metropolitan Area
Complex MediaInvestor2007 — 2016New York City Metropolitan Area
GravitantBoard of Directors2012 — 2015Austin, Texas Metropolitan Area
StoredIQBoard of Directors2007 — 2013Austin, Texas Metropolitan Area
Sipera SystemsBoard of Directors2010 — 2011Dallas-Fort Worth Metroplex
LibreDigitalBoard of Directors2010 — 2011Austin, Texas Metropolitan Area
Phurnace Software (acquired by BMC Software)Board of Directors2008 — 2009Austin, Texas Metropolitan Area
Crossroads SystemsCEO, Chairman, Founder1994 — 2003
IBMStaff Engineer1990 — 1994Austin, Texas Area; Kingston, New York

Skills & more

SaaS2Enterprise Software1Software as a Service (SaaS)1Success OrientedLeadership8Management4Strategy1Investment ManagementIntellectual Property4Business Intelligence4Software Project Management2Start-ups18

+12 more

Venture CapitalEarly Stage CompaniesGrowth AccelerationEarly Stage VenturesEarly StageStrong Business AcumenStrategic PartnershipsEntrepreneurshipBusiness DevelopmentProduct ManagementExecutive ManagementCloud Computing

From Brian's professional profile.

Deals · 1

ALKAMI TECHNOLOGY, INC.Board seat

via S3 Ventures · filed Oct 2020 · $140M raise

Attribution from SEC filings, press coverage, and firm rosters.

Other disclosed investments

Board seats

Acessa HealthAlkami TechnologyAlleviant MedicalBriggoCrossroads SystemsEndovascular EngineeringFavorFoliaGravitantLibreDigitalLiquibasePacket DesignPhurnaceSipera SystemSpectrawaveStoredIQTango Health TVA Medical VahaticorVentureMedVUV Analytics

Sources: the firm's website · SEC Form D filings.

Colleagues at S3 Ventures

Aaron Perman

General Partner at S3 Ventures

Anthony Marfisi

Associate at S3 Ventures

Anthony Marfski

Associate at S3 Ventures

Carolyn Houren

Senior Associate at S3 Ventures

Charlie Plauche

Managing Director at S3 Ventures

Eric Engineer

General Partner at S3 Ventures

Joe Curry

Principal at S3 Ventures

Kathryn Deebel

Director of Platform & Network at S3 Ventures

Network11

Aaron PermanScout

General Partner at S3 Ventures

Carolyn HourenScout

Senior Associate at S3 Ventures

Charlie PlaucheScout

Managing Director at S3 Ventures

Cotter CunninghamScout

Founder, Chair and CEO RetailMeNot at Next Coast Ventures

Ethan AustinScout

Founding Partner at Outside VC

Nicole BentzScout

Vice President at S3 Ventures

Zack ScottScout

General Partner at Norwest Venture Partners

Joe Curry

Principal at S3 Ventures

Katie Wallis

Associate at S3 Ventures

Kim Rodriguez

Venture Partner at S3 Ventures

Sarah Morgan

Vice President at S3 Ventures

Investors connected to Brian in public investor directories — a warm-intro map.

Frequently asked questions

Who is Brian Smith?: Brian R. Smith founded S3 Ventures and serves as its Managing Director. Earlier in his career he founded Crossroads Systems (Nasdaq: CRDS), taking it public in 1999 as Chairman and CEO after leading multiple financing rounds, and previously held product development roles in electrical engineering at IBM. He holds a BSEE from the University of Cincinnati and an MSEE from Purdue University.
Where does Brian Smith work?: Brian Smith is Managing Director at S3 Ventures and Board director at Vahaticor and Board director at Spectrawave and Board director at Acessa Health.
What does Brian Smith invest in?: Brian Smith invests in Enterprise Software, Fintech, Healthtech, Medical Devices, SaaS.
What check size does Brian Smith write?: Brian Smith typically writes checks of $100K – $5M.
What boards does Brian Smith sit on?: Brian Smith holds tracked board seats at Acessa Health, Alkami Technology, ALKAMI TECHNOLOGY, INC., Alleviant Medical, Briggo, Crossroads Systems, Endovascular Engineering, Favor, Folia, Gravitant.
Where did Brian Smith go to school?: Brian Smith studied at Purdue University (MSEE, Electrical Engineering); University of Cincinnati (BSEE, Electrical Engineering).