Trevi Therapeutics
NASDAQ: TRVINew Haven, US · Founded 2011 · Delaware corporation · 47 employees on LinkedIn · 4 known investors
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Trevi Therapeutics is a clinical-stage biopharmaceutical company developing Haduvio (oral nalbuphine ER), an investigational therapy for chronic cough that targets the central and peripheral cough reflex arc. It is advancing the treatment for patients with idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC).
Founders & leadership
Trevi Therapeutics was founded in 2011 by Thomas Sciascia, Jennifer Good, and Thomas Sciascia, M.D..





Board
Investors · 4
Funding
SEC filings, press & company announcements$121.7M disclosed across 4 of 10 rounds · 1900–2026
- Undisclosed amountunderwritten public offeringApr 2026Source ↗
▶$55MraisedApr 2022 · 12 investors · BiotechnologyRule 506(b)
- Michael HeffernanDirector
- Thomas SciasciaExecutive Officer
- David MeekerDirector
- James CassellaDirector
- Dominick ColangeloDirector
- Jennifer L. GoodExecutive Officer, Director
- William ForbesExecutive Officer
- Edward MathersDirector
- Anne VanLentDirector
- Lisa DelfiniExecutive Officer
- Offering amount
- $55M
- Amount sold
- $55M
- Sales commissions
- $3.3M
- Placement agents
- Needham & Company, LLC, Oppenheimer & Co. Inc., Aegis Capital Corp., Stifel, Nicolaus & Company, Incorporated
- First sale
- Apr 2022
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$3MraisedOct 2021 · 1 investors · BiotechnologyRule 506(b)
- Edward MathersDirector
- Michael HeffernanDirector
- Lisa DelfiniExecutive Officer
- James CassellaDirector
- Dominick ColangeloDirector
- Jennifer L. GoodExecutive Officer, Director
- Anne VanLentDirector
- William ForbesExecutive Officer
- Thomas SciasciaExecutive Officer
- David MeekerDirector
- Offering amount
- $3M
- Amount sold
- $3M
- First sale
- Oct 2021
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$11.8MraisedOct 2021 · 1 investors · BiotechnologyRule 506(b)
- Anne VanLentDirector
- Dominick ColangeloDirector
- William ForbesExecutive Officer
- Jennifer L. GoodExecutive Officer, Director
- Edward MathersDirector
- James CassellaDirector
- Lisa DelfiniExecutive Officer
- David MeekerDirector
- Michael HeffernanDirector
- Thomas SciasciaExecutive Officer
- Offering amount
- $11.8M
- Amount sold
- $11.8M
- Sales commissions
- $709K
- Placement agents
- Stifel, Nicolaus & Company, Incorporated, Needham & Company, LLC
- First sale
- Oct 2021
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$51.9MraisedSep 2018 · 18 investors · BiotechnologyRule 506(b)
- Thomas R. SciasciaExecutive Officer
- Michael HeffernanDirector
- Mette Kirstine AggerDirector
- Ed MathersDirector
- Chris SeiterExecutive Officer
- Annie MitsakDirector
- Jennifer L. GoodExecutive Officer, Director
- Eran NadavDirector
- David MeekerDirector
- Offering amount
- $61.9M
- Amount sold
- $51.9M
- First sale
- Jul 2017
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Competitors · 6
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In the news
Frequently asked questions
- What does Trevi Therapeutics do?
- Trevi Therapeutics is a clinical-stage biopharmaceutical company developing Haduvio (oral nalbuphine ER), an investigational therapy for chronic cough that targets the central and peripheral cough reflex arc. It is advancing the treatment for patients with idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC).
- Who founded Trevi Therapeutics?
- Trevi Therapeutics was founded by Thomas Sciascia, Jennifer Good, Thomas Sciascia, M.D. in 2011.
- Who are Trevi Therapeutics's investors?
- Trevi Therapeutics's investors include APERTURE Venture Partners, Frazier Life Sciences, New Enterprise Associates (NEA), Omega Funds.
- How much funding has Trevi Therapeutics raised?
- Trevi Therapeutics has disclosed $121.7M raised across 4 of its 10 known rounds.
- Where is Trevi Therapeutics headquartered?
- Trevi Therapeutics is headquartered in New Haven, US.





