🦊/Companies

Trevi Therapeutics

NASDAQ: TRVI

New Haven, US · Founded 2011 · Delaware corporation · 47 employees on LinkedIn · 4 known investors

Find your way into Trevi Therapeutics

48 people in our graph share verified history with the Trevi Therapeutics team — schools, employers, funds. One of them is your warm intro.

Elizabeth Stonerunlockedknows Jennifer Good · together at Rhythm Pharmaceuticals (overlapped)
knows the team · via Trevi Therapeutics
×2knows the team · via Rhythm Pharmaceuticals
×8knows the team · via Creighton University

Trevi Therapeutics is a clinical-stage biopharmaceutical company developing Haduvio (oral nalbuphine ER), an investigational therapy for chronic cough that targets the central and peripheral cough reflex arc. It is advancing the treatment for patients with idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC).

Founders & leadership

Trevi Therapeutics was founded in 2011 by Thomas Sciascia, Jennifer Good, and Thomas Sciascia, M.D..

TS
Thomas SciasciaCo-founder
JGJennifer Good
Jennifer GoodinCo-Founder, President and CEOShe co-founded the company in 2011 after serving as president and CEO of Penwest Pharmaceuticals, where she had earlier spent nearly a decade as chief financial officer. Her earlier career included corporate controller at Penford Products and audit manager at Ernst & Young, and she has served on the board of Rhythm Pharmaceuticals since 2019.
TSThomas Sciascia, M.D.
Thomas Sciascia, M.D.Co-Founder, Chief Scientific Officer
LDLisa Delfini
Lisa DelfiniinChief Financial Officer2021–2025
WFWilliam Forbes
William ForbesinChief Development Officer (CDO)2021–2022William Forbes brings more than 30 years of pharmaceutical product development experience, including founding a biotech company and serving as its CEO and President overseeing R&D, medical affairs, and manufacturing. He has contributed to regulatory approvals across multiple therapeutic areas including anti-infectives, gastrointestinal, respiratory, cardiovascular, and oncology, with expertise spanning small molecules, biologics, and drug-device combinations.
MHMichael Heffernan
Michael HeffernaninLead Independent DirectorExecutive Officer, Director at Collegium Pharmaceutical
JC
James CassellaNamed on SEC filing
DC
Dominick ColangeloNamed on SEC filing
AV
Anne VanLentNamed on SEC filing

Board

EM
Edward MathersBoard director
DM
David MeekerBoard director

Investors · 4

Funding

SEC filings, press & company announcements

$121.7M disclosed across 4 of 10 rounds · 1900–2026

  • Undisclosed amountunderwritten public offeringApr 2026
    Source ↗
$55MraisedApr 2022 · 12 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Michael HeffernanDirector
  • Thomas SciasciaExecutive Officer
  • David MeekerDirector
  • James CassellaDirector
  • Dominick ColangeloDirector
  • Jennifer L. GoodExecutive Officer, Director
  • William ForbesExecutive Officer
  • Edward MathersDirector
  • Anne VanLentDirector
  • Lisa DelfiniExecutive Officer
Offering amount
$55M
Amount sold
$55M
Sales commissions
$3.3M
Placement agents
Needham & Company, LLC, Oppenheimer & Co. Inc., Aegis Capital Corp., Stifel, Nicolaus & Company, Incorporated
First sale
Apr 2022
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
$3MraisedOct 2021 · 1 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Edward MathersDirector
  • Michael HeffernanDirector
  • Lisa DelfiniExecutive Officer
  • James CassellaDirector
  • Dominick ColangeloDirector
  • Jennifer L. GoodExecutive Officer, Director
  • Anne VanLentDirector
  • William ForbesExecutive Officer
  • Thomas SciasciaExecutive Officer
  • David MeekerDirector
Offering amount
$3M
Amount sold
$3M
First sale
Oct 2021
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
$11.8MraisedOct 2021 · 1 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Anne VanLentDirector
  • Dominick ColangeloDirector
  • William ForbesExecutive Officer
  • Jennifer L. GoodExecutive Officer, Director
  • Edward MathersDirector
  • James CassellaDirector
  • Lisa DelfiniExecutive Officer
  • David MeekerDirector
  • Michael HeffernanDirector
  • Thomas SciasciaExecutive Officer
Offering amount
$11.8M
Amount sold
$11.8M
Sales commissions
$709K
Placement agents
Stifel, Nicolaus & Company, Incorporated, Needham & Company, LLC
First sale
Oct 2021
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
$51.9MraisedSep 2018 · 18 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Thomas R. SciasciaExecutive Officer
  • Michael HeffernanDirector
  • Mette Kirstine AggerDirector
  • Ed MathersDirector
  • Chris SeiterExecutive Officer
  • Annie MitsakDirector
  • Jennifer L. GoodExecutive Officer, Director
  • Eran NadavDirector
  • David MeekerDirector
Offering amount
$61.9M
Amount sold
$51.9M
First sale
Jul 2017
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Competitors · 6

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StockTwits14 shared keywordsStocktwits operates an online community platform where investors and traders share ideas, analysis, and trade discussions organized around stock tickers. The page presented is its community guidelines rather than a product description.

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In the news

Frequently asked questions

What does Trevi Therapeutics do?
Trevi Therapeutics is a clinical-stage biopharmaceutical company developing Haduvio (oral nalbuphine ER), an investigational therapy for chronic cough that targets the central and peripheral cough reflex arc. It is advancing the treatment for patients with idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC).
Who founded Trevi Therapeutics?
Trevi Therapeutics was founded by Thomas Sciascia, Jennifer Good, Thomas Sciascia, M.D. in 2011.
Who are Trevi Therapeutics's investors?
Trevi Therapeutics's investors include APERTURE Venture Partners, Frazier Life Sciences, New Enterprise Associates (NEA), Omega Funds.
How much funding has Trevi Therapeutics raised?
Trevi Therapeutics has disclosed $121.7M raised across 4 of its 10 known rounds.
Where is Trevi Therapeutics headquartered?
Trevi Therapeutics is headquartered in New Haven, US.