Boston · Pre-Seed–Series A · 62 people tracked
Also known as Pillar · PILLAR COMPANIES MANAGEMENT, LLC
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Investment thesis
Pillar VC backs technically brilliant founders from the very beginning, partnering at inception with those pursuing ambitious technical breakthroughs. The firm believes a golden age of innovation is underway, in which advances such as AI-driven drug discovery, global research networks, and powerful new experimental tools can transform bold ideas into world-changing companies. Its focus centers on deep technology and science-driven startups, particularly at the intersection of AI, biotechnology, and healthcare, supporting founders who see past what seems impossible toward what they view as inevitable outcomes.
Source: firm website, verified Sep 29, 2026.
Team · 62 people
from the firm's website & public directoriesFounder mafia
The Pillar VC mafia →28 people who came through Pillar VC went on to found or lead other companies.
What they invest in
from 80 of 120 portfolio companiesAI & Machine Learning ×41Biotech ×23Healthtech ×18SaaS ×17Deep Tech ×16Enterprise Software ×15Fintech ×12Hardware ×9
HQs:United States×53Germany×2Canada×1Spain×1United Kingdom×1
Who they back
founder profiles across 52 portfolio companiesFounding team size:solo founder×152 founders×173 founders×94+ founders×11
Where their founders studiedfrom 66 founders with education data
Massachusetts Institute of Technology ×10Harvard Business School ×6Harvard University ×6University of California, Berkeley ×6University of Cambridge ×3University of Michigan ×3Boston College ×2Brown University ×2
What their founders studiedfrom 64 founders with field-of-study data
Engineering ×18Computer Science ×17Business & Management ×11Life Sciences ×7Economics ×6Chemistry ×5Mathematics & Statistics ×4Physics ×4
Where their founders worked beforefrom 71 founders with career history
Massachusetts Institute of Technology ×5Google ×4Harvard Medical School ×4Microsoft ×4Beth Israel Deaconess Medical Center ×3Brightcove ×3Harvard University ×3MIT Media Lab ×3
Accelerator rootsportfolio companies that came through a program
26 founders hold a PhD · 7 hold an MBA (of 71 with degree data)
Investments · 120 tracked
founders shown can be your intro pathBy year:2026 · 72025 · 112024 · 52023 · 62022 · 92021 · 92020 · 52019 · 22018 · 22017 · 22016 · 159 dated
Circle provides a full-stack platform for digital finance, combining blockchain infrastructure, stablecoins (USDC, EURC), and payment networks to enable borderless value exchange and financial access globally.
AI & Machine LearningCrypto & Web3FintechNew York City, US
Jeremy Allaire(Founder)inPatrick Sean Neville(Director)Sid Yadav(Founder)inSean Neville(Founder)inP. Sean Neville(Director)Heath Tarbert(Executive Officer)in
Co-investors10T FundAccelalphabet angelsAlumni VenturesaVentureAxevil Capital+34 more
Adaptilens develops a biomimetic accommodating intraocular lens (A-IOL) for cataract and vision correction, an ophthalmic medical device.
BiotechHardwareHealthtechMedical DevicesChestnut Hill, US
Liane Clamen(Inventor / Founder)in
BoardJohn Andres(Director)Terry Kim(Director)William Shea(Director)Robert Doris(Director)
Board seatJamie Goldstein· per SEC Form D
Botkeeper provides an AI-driven bookkeeping platform that automates manual accounting tasks and layers in dedicated accountant services, for accounting firms and their business clients.
AI & Machine LearningFintechSaaSBoston, US
Enrico Palmerino(Founder)inAngelina Palmerino(Co-Founder & Chief Product Officer)inSallie Halsey(Chief Operations Officer)inJessica Veiga(Chief Revenue Officer)inTravis Cherry(Chief Technology Officer)inErica Cramer(Senior Vice President, Client Services)in
Co-investorsPoint72 VenturesCorrelation VenturesGradient VenturesGreycroftHigh AlphaPeak State Ventures
Hellotickets operates a global platform connecting travelers with tours and activities across 15 countries.
MarketplacesTravel & HospitalityMadrid, ES
Jorge Díaz Largo(Co-founder)inAlberto Martínez(Co-founder)in
Co-investorsTechstars
Modulate Bio develops small-molecule GABAA positive allosteric modulators to treat neurological disorders including Essential Tremor, epilepsy, and anxiety.
BiotechDeep TechHealthtechAllston, US
Dario Doller(Co-founder)inKevin Hodgetts(Founding Lab / Co-founder)inAndrew Thomson(Executive Officer, Director, Promoter)in
Co-investorsPalo Santo VCHealthspan Capital
Thymmune Therapeutics develops a machine learning-driven thymic cell engineering platform that mass-produces iPSC-derived thymic cells to restore immune function affected by aging and disease.
AI & Machine LearningBiotechLongevityCambridge, US
Stan Wang(MD, PhD)inBing Lim(MD, PhD)inManish Jainin
Co-investorsNYBC Ventures
Acelab provides a platform for architects and construction professionals to research, select, and document building materials.
AI & Machine LearningConstruction TechEnterprise SoftwareSaaSBrooklyn, US
Vardhan Mehta(Executive Officer, Director)inDRIES CARMELIET(Executive Officer, Director)inDave Lemont(Executive Chairman)inEmily Farirbairn(Director)
BoardMatthew Hayes(Director)inParker McKee(Director)in
Board seatRuss Wilcox· per SEC Form D
Co-investorsAlpaca VCCorigin VenturesDesignXDraper AssociatesJLL Spark Global VenturesNavitas Capital+2 more
Fluent Metal makes a metal 3D printer that uses a single-step wire-to-drop process to print metal parts directly, without post-sintering, laser, or powder.
Advanced ManufacturingHardwareNew MaterialsCambridge, US
Peter Schmitt, PhD(Founder)in
BoardTheodore Frederick Lee(Director)
Board seatJamie Goldstein· per SEC Form D
Glia offers a banking AI platform that automates inbound and outbound customer interactions and internal workflows across a financial institution's core, engagement, and other systems.
AI & Machine LearningFintechSaaSNew York City, US
Hari Balakrishnan(Mr. Balakrishnan is the President of the Issuer.)Justin DiPietro(Founder)inDaniel Michaeli(Founder)inMohammadreza Alizadeh Attar(Director, Executive Officer)
Board seatJamie Goldstein· per SEC Form D · $13.5M raise · filed Dec 2025
Co-investorsEntrepreneurs Roundtable Accelerator (ERA)Flying Fish VenturesGray Line PartnersInnovating CapitalInsight PartnersRemarkable Ventures+3 more
Kula Bio develops bacterial propagation and feeding systems that enhance the nitrogen-fixing capabilities of naturally occurring microbes for agricultural applications.
AgTechBiotechNatick, US
Daniel Nocera(Director)Harrison Yoon(CEO / BOD)inWilliam Brady(Founder)Bill Brady(Founder)Kelsey Sakimoto(Founder)
Board seatJamie GoldsteinRuss Wilcox· per SEC Form D
Co-investorsArgonautic VenturesBoxGroupCollaborative FundEmbark VenturesiSelect FundLowercarbon Capital+4 more
Latent Labs develops generative AI models for protein design and builds biological platforms to validate AI-driven designs.
AI & Machine LearningBiotechDeep TechLondon, GB
Simon Kohl(Founder)in
BoardJohn Cassidy(Director)
Board seatTony Kulesa· per SEC Form D
Co-investors8VCFlying Fish VenturesIsomer CapitalKindred CapitalRadical VenturesSofinnova Partners+2 more
Neural Magic (now part of Red Hat) offers open source AI infrastructure for deploying, managing, and scaling AI inference, agentic AI workflows, and AI-powered applications across hybrid cloud and various hardware.
AI & Machine LearningCloud ComputingEnterprise SoftwareCambridge, US
Alexander Matveev(Founder)Nir Shavit(Founder)
Board seatJamie Goldstein· per SEC Form D
Co-investorsAndreessen HorowitzComcast VenturesNew Enterprise Associates (NEA)
Critical minerals midstream refining company building modular technology to convert industrial scrap, black mass and primary feeds into refined nickel, cobalt, copper and rare earth products for Western supply chains.
Burlington, US
Megan O'Connor(Founder)inChad D. Vecitis, PhD(Co-Founder and Chief Scientist)Desirée Plata, PhD(Co-founder & Science Advisor)Gabi Knesel(Executive Officer)Chad Vecitis(Founder)
BoardRaffi Freeman(Executive Officer)in
Board seatBrian Baynes· per SEC Form D · $15M raise · filed May 2026
Co-investorsAutodesk FoundationBroadscaleClean Energy VenturesMuus Climate PartnersVoLo Earth VenturesWovenEarth+2 more
Scripta offers AI-powered prescription navigation solutions that help members, employers, and health plans identify clinically appropriate and affordable medication alternatives.
AI & Machine LearningHealthtechSaaSWellesley, US
Paul S. Bradley(Co-founder and Chief Medical Officer)inEric Levin(CEO)Ferrin Williams(Chief Pharmacy Officer)in
BoardSanders Pitman(Director)Bob Greene(Director)in
Board seatRuss Wilcox· per SEC Form D
Co-investorsEastside PartnersSeedToBContour Venture Partners
Tycho.AI builds Voyager, a hardware and software stack for autonomous navigation and edge intelligence that operates in GPS- or comms-denied environments for defense and national security applications.
AI & Machine LearningDefense TechRoboticsCambridge, US
Sertac Karaman(Executive Officer, Director)inThomas Kenney(Executive Officer, Director)
BoardRichard D. Clarke(Director)
Board seatJamie Goldstein· per SEC Form D
Co-investorsFirstMark Capital
Idira is an identity security platform providing privileged access management (PAM), machine identity security, and governance for human, machine, and AI agent identities across enterprises.
CybersecurityEnterprise SoftwareSaaSWellesley, US
Nitin Sonawane(Founder)
BoardDeepak Taneja(Founder)Amish Jani(Director)in
Board seatJamie Goldstein· per SEC Form D
Co-investorsFirstMark CapitalTola Capital
Abridge builds AI software that converts clinical conversations into structured insights for healthcare providers.
AI & Machine LearningDigital HealthHealthtechPhiladelphia, US
Shiv Rao(Founder)inSandeep Konam(Founder)inJulia Chapin(Founder)Sagar Sanghvi(Executive Officer)inFlorian Metze(Founder)Shivdev Rao(Founder)
Co-investorsAlpha Square Groupalphabet angelsAndreessen HorowitzAtria VenturesBessemer Venture PartnersCapitalG+25 more
Addis Energy develops technology that combines oil and gas engineering expertise with advanced research to access energy and resources from subsurface geology.
CleantechDeep TechEnergySomerville, US
Michael Alexander(Founder)inCharlie Mitchell, P.E.(Founder)inIwnetim Iwnetu Abate(Director)Oliver Charles Mitchell(Director)
BoardLaurie Menoud(Director)inMichael Kearney(Director)in
Co-investorsAt One VenturesBlindspot Ventures Management CoThe Engine VenturesVoyager PartnersFounders FundKhosla Ventures
Algofi develops financial infrastructure designed to lower entry barriers and increase accessibility in financial services.
Crypto & Web3Fintech
Owen ColegroveJohn ClarkePaul Colella(Founding Engineer)
Co-investorsArrington CapitalY CombinatorAlgorand FoundationArrington XRP CapitalBorderless VentureBrevan Howard Digital+10 more
The Algorand Foundation supports and grows the Algorand blockchain ecosystem by improving the developer experience, contributing to core protocol infrastructure and standards, and enabling decentralized governance.
Crypto & Web3Deep TechDeveloper ToolsFintechQuantum Computing
Silvio Micali(Founder)inSteven Kokinos(Founder)
Co-investorsAlumni VenturesAndromeda CapitalArrington CapitalBasecamp FundBig Candle CapitalBixin Capital+27 more
Amber Bio is a biotechnology company developing a novel RNA writing platform capable of multi-kilobase gene edits that can treat multiple mutations across patients with a single product.
AI & Machine LearningBiotechDeep Tech
Jacob Borrajo, PhD(Founder and CEO)Basem Al-Shayeb(Founder)Jacob Borrajo(Founder)inJacob Borrajo Basem Al-Shayeb(Founder)
Co-investorsPlayground GlobalAndreessen HorowitzHummingbird Ventures
Amplifyer develops liquid biopsy technology aimed at improving outcomes for cancer patients.
BiotechHealthtechMedical DevicesLexington, US
Annie MurphyinEric K. Huang(Executive Officer, Director)J. Christopher Love(Director)Viktor A. Adalsteinsson(Director)
BoardThomas de Vlaam(Director)inStanley Lapidus(Director)in
Premium social video app for asking questions of world-class experts; acquired by Whoop in 2023.
Digital HealthHardwareWellness & Fitness
Co-investorsUnderscore VC
A layer 1 blockchain engineered to evolve.
Avery Ching(Founder)Mo Shaikh(Founder)in
Co-investorsBorderless VentureMEXC VenturesVariant FundAndreessen HorowitzBixin VenturesDelta Blockchain+7 more
Arvada Therapeutics is a biotechnology company focused on drug development for rare and degenerative diseases, working across preclinical research and clinical stages.
BiotechHealthtechLongevity
ShiYin Foo(Founder and CEO)Ryan Tyler(Co-founder and SVP of Preclinical Research)
Co-investorsNovartis Venture Fund
Asimov develops a computer-aided design platform for genetic engineering, enabling designers to program living cells by applying abstraction, standardization, and modeling to biology.
AI & Machine LearningBiotechDeep TechDeveloper ToolsBoston, US
Chris Voigt(Founder)inAlec Nielsen(Founder)inRaja Srinivas(Founder)inDouglas Densmore(Founder)inChristopher Voigt(Founder)Doug Densmore(Founder)
Co-investorsAndreessen HorowitzDCVC (Data Collective)K5 GlobalKoch Disruptive TechnologiesWingAME Cloud Ventures+2 more
BigUp is a creator-led platform that combines live streaming, community features, and prediction markets into a format it calls "Predictainment." The company is currently rebuilding the experience ahead of a relaunch.
Creator EconomyMedia & EntertainmentSocial
Co-investorsNeotribe Ventures
Blockstamp is a software platform designed to organize information, enable automation, and provide analytics for manufacturing and maintenance operations to increase efficiency and trust.
Advanced ManufacturingAI & Machine LearningConstruction TechEnterprise SoftwareRoboticsSaaSLos Angeles, US
Daniel Jones(Founder)Michael McHugh(Founder)inZach ButlerDaniel S. Jones(Founder)in
Co-investorsY CombinatorAltos VenturesGeneral CatalystPioneer
BoolSi is a platform that compiles hot C or C++ functions in embedded applications into custom digital logic co-processors, generating, verifying, and deploying hardware bitstreams without HDL or a parallel codebase.
Developer ToolsHardwareSemiconductorsBoston, US
Mihailo Isakov(Executive Officer, Director)Branko Milosavljevic(Executive Officer)
Co-investorsCoalitionFifth Quarter Ventures
Bridge is a stablecoin payments platform that gives businesses infrastructure to receive, store, convert, issue, and spend stablecoins through a single API.
Crypto & Web3Data & InfrastructureFintech
Zach Abrams(Founder)inSean Yu(Founder)
Co-investors1confirmationArtisanal VenturesChemistryCoinbase VenturesDepartment of XYZFirebolt Ventures Management Company, Llc+12 more
Catena is building a financial institution for AI agents, combining a technology platform with a national trust bank that lets agents transact under human-defined policies with deterministic policy enforcement, audit trails, and verifiable agent identity.
AI & Machine LearningData & InfrastructureEnterprise SoftwareFintech
Sean Neville(Founder)inMatt Venables(Founder)inBrice Stacey(Founder)
Co-investorsa16z cryptoAcrew CapitalAndreessen HorowitzBreyer CapitalCircle VenturesCoinbase Ventures+10 more
Catena is building a regulated national trust bank combined with a technology platform specifically for AI agents, enabling compliant transactions under human-defined policies.
AI & Machine LearningEnterprise SoftwareFintech
Sean Neville(CEO)Matt Venables(CTO)
Co-investorsCoinFunda16z cryptoBalaji SrinivasanBreyer CapitalCircle VenturesCoinbase Ventures+1 more
Cimulate is an LLM-based operating system for e-commerce that uses natural language understanding to model customer intent in real-time and drive conversion.
AI & Machine LearningE-commerceSaaS
Vivek Farias(Founder)John Andrews(Founder)
Co-investorsLFX Venture PartnersSierra VenturesCommerce VenturesSpark Capital
Compound Foods develops alternative coffee and cocoa ingredients made from upcycled, climate-resilient sources to address supply chain volatility and environmental impact of traditional coffee and cocoa production.
Climate TechFoodTech
Maricel Saenz(Founder)in
Co-investorsAmplifica CapitalCollaborative FundEndurance28Female FoundersJuniperMagma Partners+8 more
Modern upscale furniture rental with flexible financing
Co-investorsOutbound VenturesCoVentureRiverPark Ventures
Day AI is an AI-native CRM that assembles and maintains customer records automatically from a company's communications, replacing manual data entry with generated, always-current context.
Michael Pici(Founder)inChristopher O'Donnell(Founder)inChristopher O'Donnell Michael Pici(Founder)
Co-investorsInspired CapitalPermanent Capital VenturesPreston-Werner VenturesSequoia CapitalStage 2 CapitalConviction+2 more
Desktop Metal develops additive manufacturing (3D printing) platforms and materials for production-volume manufacturing, targeting engineers, designers, manufacturers, and medical professionals.
Advanced ManufacturingDeep TechHardwareBurlington, US
Ric Fulop(Founder)inA. John Hart(Founder)inChristopher Schuh(Founder)Ely Sachs(Founder)Jonah Myerberg(Founder)Rick Chin(Founder)
Co-investorsBaukunstBMW i VenturesConductive VenturesConstruct CapitalDCVC (Data Collective)Founder Collective+13 more
Edison Scientific builds AI agents for scientific research, enabling researchers and industries to accelerate discovery across biology, chemistry, physics, and related domains.
AI & Machine LearningBiotechDeep TechSan Franciso, US
Andrew White(CTO, Co-Founder)inSam Rodriques(CEO, Co-Founder)in
BoardNick Leschly(Director)inJeff Huber(Director)in
Co-investorsHAWKTAILNVenturesNVIDIAPage One VenturesSpark CapitalStriker Venture Partners+3 more
EO is a verification and intelligence layer for deployed GPU compute infrastructure, converting fragmented hardware telemetry into a continuously verified record of each asset's identity, condition, custody, degradation, and economic value.
Data & InfrastructureDeep TechFintech
Co-investorsEntrée Capital
Euler Biologics develops antibody-based therapies aimed at preserving and enhancing physical function in older adults to support healthy aging and functional independence.
BiotechHealthtechLongevity
Co-investorsSoma CapitalAxial VC
An AI research lab building algorithmic trading systems and infrastructure for quantitative market prediction.
AI & Machine LearningFintechSan Francisco, US
Owen ColegrovePrakul Singh(Recruiter)
Co-investorsY CombinatorStandard Capital
Everyrealm develops infrastructure and deploys capital for crypto and community-driven projects, investing in and building across blockchain protocols and platforms to connect digital economies.
Cloud ComputingCrypto & Web3GamingSocialLakeville, US
Janine Yorio(CEO, Co-Founder)inJesse Stein(Co-Founder)in
BoardAndrew Durgee(Director)Youngro Lee(Director)
Co-investorsHasheda16z cryptoAndreessen HorowitzCoinbase VenturesD1 VenturesDragonfly+5 more
Operating system and marketplace for semiconductor fabrication connecting designers, fabs, equipment makers, and suppliers.
Boston, US
Jack Muller(Founder)inJan Tiepelt(Founder)inEyal Perry(Founder)in
Co-investorsBlindspot Ventures Management Co
GALY develops biocrafted alternatives to conventionally extracted materials like cocoa and cotton, positioning grown products as sustainable replacements for industries reliant on extractive supply chains.
AgTechBiotechCircular EconomyFoodTechNew MaterialsBoston, US
Luciano Bueno(Founder)inAmancio Ortega. Known for(Founder)Tim Draper(Founder)
BoardCarmichael Roberts(Director)inRyan Panchadsaram(Director)
Co-investorsAgronomicsArtesianBabel VenturesBreakthrough Energy VenturesBrincMaterial Impact+3 more
Gekit provides a memory infrastructure layer for AI agents, organizing fragmented context from internal systems, human inputs, and prior agent outputs into a structured, pre-indexed system agents can access within the agent loop.
AI & Machine LearningData & InfrastructureDeveloper Tools
Sivaprasad Sudhir(Founder)in
Higharc provides construction operations management software for homebuilders, offering a single source of truth for plan portfolio management including plans, elevations, options, standards, pricing and sales availability across communities.
AI & Machine LearningConstruction TechPropTechSaaS
Marc Minor(Founder)inMichael Bergin(Founder)inPeter Boyer(Founder)inThomas Holt(Founder)in
Co-investorsFifth WallFounder CollectiveInsight PartnersJavelin Venture PartnersLux CapitalMetaProp+16 more
Hometap operates a home equity investment (HEI) platform that lets U.S. homeowners access their home equity without monthly payments, while offering institutional and individual investors exposure to U.S. residential real estate appreciation through structured capital market vehicles.
FintechPropTechBoston, US
Co-investorsAmerican Family VenturesG20 VenturesGallatin Point Capital
Jellyfish provides software engineering intelligence and team management tools for engineering organizations.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareFintechSaaS
David Gourley(Founder)inAndrew Lau(Founder)Phil Braden(Founder)Philip Braden(Founder)
Co-investorsAccelFirst Star VenturesInsight PartnersWingTiger Global Management
JobGet operates a network of mobile-first job marketplaces—including JobGet, Snagajob, Foh & Boh, and Seasoned—that connect hourly and frontline workers with employers using AI-powered skills matching.
AI & Machine LearningHR TechMarketplaces
Tony Liu(Founder)inPeter Lee(Founder)in
Co-investorsData Point CapitalFlow CapitalJAZZ Venture PartnersEqual Opportunity VenturesSanabil Investments
Kuebix, by FreightWise, is a SaaS transportation management system (TMS) for midmarket and larger shippers, supporting multi-modal freight planning, shipment execution, tracking, and analytics.
Enterprise SoftwareLogistics & Supply ChainSaaSMaynard, US
Daniel Clark(Executive Officer)Raymond DeSabato Jr.(Executive Officer, Director)
BoardJeremy Sclar(Director)Eugene Kuznetsov(Manager)Richard Sousa(Director)
Kula is an AI-native applicant tracking system that combines sourcing, CRM, screening, scheduling, interview note-taking, and analytics into a single hiring workflow.
AI & Machine LearningHR TechSaaSSan Francisco, US
Achuthanand Ravi(Founder)inSuman Kumar Dey(Founder)inSathappan M(Founder)
Co-investorsNorwest Venture PartnersSquare Peg CapitalTogether FundAgFunderBoxGroupCollaborative Fund+8 more
Lamin provides a lineage-native lakehouse platform for biological R&D that enables scientists to query, trace, and validate complex biological datasets across academia, biotech, and pharma.
AI & Machine LearningBiotechData & InfrastructureDeveloper ToolsEnterprise SoftwareHealthtechMunich, DE
Alex Wolf(CEO)inSunny Sun(Founder)inFrederic Enard(Co-CTO & Founding Engineer)inAlex T. Wolf(Founder)Ollie Baskeyfield(Recruiter)
Co-investorsPioneerY CombinatorDimension CapitalNielsen Investments LP
LightSource provides an AI-powered operating system that connects engineering, procurement, and suppliers in one platform, handling BOM management, RFQs, bid normalization, tariff exposure analysis, and supplier award decisions.
Advanced ManufacturingAI & Machine LearningSaaSSan Francisco, US
Idan Mintz(Founder)inSpencer Penn(Founder)in
Co-investorsBain Capital VenturesJ2 VenturesLightspeed Venture Partners
Logic is a production AI platform where teams write a natural language spec that is turned into a spec-driven agent with typed REST APIs, auto-generated tests, version control, and multi-model routing across providers like GPT, Claude, and Gemini.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareSaaSSeattle, US
Steve Krenzel(Founder)inJess Garms(Founder)in
Co-investorsAudacious8VCAlumni VenturesBison VenturesDefined VCGeneral Catalyst+3 more
Matterworks builds foundation models (its Large Spectral Model, delivered via the cloud-based Pyxis platform) that analyze biochemical omics and mass spectrometry data to make predictions for life science R&D.
AI & Machine LearningBiotechDeep TechHealthtech
Jack (J.M.) Geremia(Founder)inEric Carlson, PhD
BoardTony KulesainMichael Lavinin
Co-investorsDYDX CapitalGermin8 VenturesiGlobe PartnersIntermountain HealthOMX VenturesWing+1 more
Mesoware builds a combined hardware-and-software automation system for physical manufacturing, integrating robots, vision, tooling, and safety into modular production lines while its software turns product specs into assembly plans validated in simulation.
Advanced ManufacturingHardwareRobotics
Metri is a biotech company developing first-in-class, disease-modifying therapeutics for endometriosis and other uterine diseases originating in the endometrium.
BiotechFemTechHealthtech
Ashley Abel(Co-Founder & CEO)inBerna Sozen, PhD(Academic Co-Founder & SAB Chair)
Co-investorsFifty YearsPace Ventures
Nabla is a drug development company that applies design discipline and scientific rigor to the development of new medicines.
AI & Machine LearningBiotechDeep TechHealthtechBoston, US
Surge Biswas(Founder)inFrances Anastassacos(Founder)inGeorge M. Church(Founder)Surge Biswas Frances Anastassacos(Founder)
Co-investorsCantos VenturesFifty YearsPetriRadical VenturesSparta GroupY Combinator+6 more
Nephrogen develops AI-powered AAV delivery vehicles for genetic medicines targeting kidney and pancreatic diseases.
AI & Machine LearningBiotechData & InfrastructureHealthtechMedical DevicesNew York City, US
Demetri Maxim(Founder and CEO)Vivek Bhalla(Chief Medical Officer)
Co-investorsChicago Early Growth Ventures (CEGV)Novogenia GmbHStartXTechstarsY CombinatorZAKA VC+14 more
BiotechBoston, US
Virginia Burger(Executive Officer, Director)
Co-investorsPetriRA Capital
Odysee builds AI-powered software for airline schedule planning, offering data-driven tradeoff analysis, stress-test simulation, and automated schedule recommendations.
AI & Machine LearningMobility & TransportationSaaS
Julian Chandra(Founder)in
Co-investorsUP Partners
OnDeck develops video understanding technology for enterprise customers, leveraging vision language models grounded in real data to enhance reliability beyond standard off-the-shelf approaches.
AI & Machine LearningData & InfrastructureEnterprise SoftwareSaaSVancouver, CA
Alexander Dungate(CEO)inSepand Dyanatkar(CTO)inJustin Chan(Founding Engineer)Elliott Piercy(ML Engineer)Lucy Gordon(Operations Lead)
Co-investorsGV (Google Ventures)MaC Venture CapitalPanache VenturesRRE VenturesSapphire VenturesY Combinator+5 more
OpenHands is an open-source platform for building and deploying AI coding agents that can be deployed locally or across an organization.
AI & Machine LearningCloud ComputingDeveloper ToolsEnterprise Software
Robert Brennan(Founder)inGraham Neubig(Founder)inXingyao Wang(Founder)inBen Solari(CRO)in
Co-investors645 VenturesAlumni VenturesBetaworksFujitsu VenturesMadrona Venture GroupMenlo Ventures+3 more
AI-powered pathology for improved patient outcomes
Boston, US
ANDREW BECK(Executive Officer, Director)inADITYA KHOSLA(Executive Officer, Director)Aditya Khosla(Founder)Andy Beck(Chief Executive Officer, Co-founder)
BoardMICHELLE DIPP(Director)STANLEY LAPIDUS(Director)in
Co-investors8VCBIOSPRING PARTNERSFairhaven Capital PartnersGeneral CatalystHighsage VenturesMerck Global Health Innovation Fund+6 more
Cloud-based AI platform helping healthcare providers manage the patient lifecycle.
Fiza Shaukat(Founder)in
Co-investorsAntlerBantam Group
PillPack is a full-service pharmacy that organizes and delivers medications to customers, managing automatic refills and coordinating directly with doctors and insurance providers.
Digital HealthHealthtechManchester, US
Timothy Parker(Chief Executive Officer, Director)inElliot Cohen(Chief Technology Officer, Director)inTJ Parker(Founder)in
BoardDavid Frankel(Director)inJon Karlen(Director)Fred Destin(Director)
Co-investorsAccelAccompliceACME CapitalBoxGroupCRV (Charles River Ventures)Entrée Capital+12 more
Portal Biotech develops bench-top instruments that use nanopore biosensors coupled with machine learning to detect, sequence, and characterise single protein and metabolite molecules, revealing modifications, mutations, and isoforms.
AI & Machine LearningBiotechDeep Tech
Co-investorsEarlybird Venture Capital
Quadratic 3D develops volumetric 3D printing technology using a no-supports, high-speed fabrication process aimed at mass customization for commercial and industrial applications.
Advanced ManufacturingDeep TechHardware
Sam Sanders(Co-founder)in
Co-investorsSafar PartnersSierra Ventures
Range Bio (Range Biotechnologies) develops next-generation diagnostics using translational proteomics for applications in human health.
BiotechHealthtechMedical Devices
Brandon Wilson, Ph.D.(Co-founder & CEO)Brandon Wilson(Founder)inNicolo Maganzini(Founder)Tom Soh(Founder)
Co-investorsArtis VenturesCivilization Ventures Management, LlcFifty YearsHAWKTAILPage One VenturesPear VC
Rarefied develops solar-powered propulsion systems that use sunlight for sustained flight in the upper atmosphere (30-100 km) without conventional fuel.
Climate TechDeep TechDefense TechSpace Tech
Ben Schafer(Founder)in
Reclaim uses AI combined with human advocacy to help families, employees, and employers optimize their healthcare spending and get more value from benefits programs.
AI & Machine LearningDigital HealthHealthtech
Nataly Youssef(CEO & Founder)
Unlocking private markets for investors and institutions across the globe.
Elkhorn, US
Peter Green(Founder)inDonald Moore(Executive Officer, Director)Gary Thompson(Director)Stephen McCown(Executive Officer)
Co-investorsBlockchain CoinvestorsBrighter CapitalCharge VCDigital StrategiesGood Growth CapitalHack VC+11 more
Rowan offers a web app and Python API for molecular design, simulation, and property prediction, including workflows for pKa, bond strength, redox potentials, protein-ligand binding affinity, and ADME properties.
AI & Machine LearningBiotechSaaSAllston, US
Arien Wagen(Executive Officer, Director)Corin Wagen(Executive Officer, Director)in
Co-investorsAI Grant
Shimmer provides coaching, community, and digital tools designed specifically for people with ADHD, combining expert guidance with peer support to help them reach their potential.
Digital HealthHealthtechMental HealthWellness & FitnessSan Francisco, US
Vikram Sreedhar(Founder)inChris Wang(Founder)inChristal Wang(Founder)inJon Wangin
Co-investorsHoneystone VenturesStartXY CombinatorGaingelsKoa LabsWefunder+1 more
Shopped provides a multiplayer collaboration layer for AI agents, adding permissions, shared context, ownership, and approval workflows so teams can coordinate and act on agent-generated analyses and recommendations.
AI & Machine LearningFuture of WorkSaaS
Josh Silverman(Founder)in
Simbe provides retail inventory and monitoring solutions combining computer vision, robotics, RFID, and fixed sensors for retail businesses.
AI & Machine LearningRetail TechRoboticsSouth San Francisco, US
Brad Bogolea(Founder)inMirza Akbar Shah(Founder)Jeff Gee(Founder)Mirza Shah(Founder)
BoardRyan Gembala(Director)inSubodh Gupta(Director)in
Co-investors7percent VenturesActivant CapitalAnorak VenturesComet LabsEastward Capital PartnersHemisphere Ventures LLC+12 more
Skeletalis is developing OASIS, a targeted small-molecule platform for musculoskeletal and bone health that concentrates therapy at sites of active bone loss while preserving the body's natural bone remodeling.
BiotechDeep TechHealthtech
Co-investorsage1KdT Ventures
Sofar Sounds organizes intimate live music concerts in unconventional venues such as lofts, cafes, and private spaces, connecting audiences with emerging and local artists.
ConsumerMarketplacesMedia & EntertainmentSomerville, US
Raphael Eleazar Offer(Director)James Lucchese(Executive Officer, Director)
BoardScott Russell Tobin(Director)inMalcom Ferguson(Director)
Co-investorsBattery VenturesLocalGlobeOctopus VenturesRaptor GroupThe Chernin Group (TCG Crypto)Union Square Ventures (USV)+1 more
Soofa manufactures and operates solar-powered digital kiosks for outdoor advertising and city communications.
AdTechCleantechGovTechHardwareIoTBoston, US
Sandra Ferguson(Founder)in
Co-investorsBantam GroupEastward Capital PartnersMomenta VenturesThe E14 FundUnderscore VCAccomplice
Sourgum provides technology solutions for the waste and recycling industry.
Circular EconomyEnterprise SoftwareLogistics & Supply ChainMarketplaces
Joe DiNardiinLuciano DiNardiinJoe DiNardi-Mack(Founder)in
Co-investors186 VenturesFounder CollectiveRiverPark VenturesSuffolk TechnologiesWorkshop Venture PartnersBroadway Venture Partners+4 more
TALLA is a video analytics platform that converts a site's existing security cameras into monitoring tools by letting operators write rules in plain English, then generating real-time alerts with attached evidence frames.
AI & Machine LearningCybersecurityEnterprise SoftwareBrookline, US
Robert C. May(Executive Officer, Director)
BoardRichard Levandov(Director)
Co-investorsFirst Star VenturesKnockout CapitalLaunchCapitalFirst Star VenturesGlasswing VenturesHyperplane Venture Capital+2 more
Design and automation technology for textile manufacturing
Co-investorsAsymmetric Capital PartnersFounder CollectiveRoot Ventures Manager, Llc
Verve Motion develops the SafeLift exosuit, a wearable device designed to reduce workplace injuries and increase productivity for physically demanding jobs.
Future of WorkHardwareLogistics & Supply ChainRoboticsCambridge, US
Ignacio Galiana(Founder)in
Co-investors515 VenturesConstruct CapitalCybernetix VenturesFounder CollectiveOUP (Osage University Partners)Safar Partners
Videa builds AI tools for dental clinicians to help identify, document, and communicate care while reducing operational burden in dental practices.
AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechCambridge, US
Robert Gaudin(Executive Officer, Director, Promoter)inFlorian Hillen(Founder)in
Co-investors515 VenturesAvenir Growth CapitalLinden CapitalThreshold VenturesBAM VenturesSpark Capital+1 more
Vivere is a product development partner that helps brands, influencers, and companies ideate, create, manufacture, and distribute consumer product lines across categories including beauty, wellness and health, baby, pet care, and home and garden.
ConsumerDirect to ConsumerE-commerceWellness & FitnessHamburg, DE
Co-investorsArmada Investment AGCAL InnovationFf Venture CapitalGeneral CatalystRockaway VenturesBerkeley Frontier+2 more
Voluna provides mobile Neutron Activation Analysis systems that collect subsurface geochemical data in real time for mineral exploration.
AgTechAI & Machine LearningDeep Tech
Alexander Strange(Founder & CEO)inDr. Aaron Olson(Founder & CTO)inElias Fernandini(Founder & COO)in
Co-investors2045 Ventures
Yardstick develops soil carbon measurement technologies to reduce the cost of measuring soil organic carbon and enable evidence-based climate-positive agriculture practices.
AgTechCleantechClimate TechData & InfrastructureDover, US
Christopher Tolles(Executive Officer, Director)Kevin Meissner(Founder)Chris Tolles(Founder)Evan Arnold(Founder)
Co-investorsBreakthrough Energy VenturesCultivian Sandbox VenturesLowercarbon CapitalPetriWorkshop Venture PartnersExtantia Capital+1 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Knox HoldingLaunchPad Software, Inc.MyA HealthRekenerTopologic Technologies, Inc.Ayo ElectronicsCipherMode LabsDrosera BioHaloKnox FinancialLeibniz AiLiza HealthManadiaMinus CoffeeMirianPortalPre-seed (First Capital In)Pre-seed/SeedScout / SeedSecondarySeed (First Capital In)SofarSpherexSunlightT33VerveVideaVivere OncotherapiesWaeveZilla
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 3
1 IPOs · 2 acquisitionsCircleNYSE: CRCLNeural Magicacq. by Red HatAnyquestionacq. by WHOOP
Portfolio news
latest coverage across their companies
Nth Cycle · wastedive.com · Aug 25, 2026
Higharc · prnewswire.com · Jun 30, 2026
Boolsi · finsmes.com · Jun 18, 2026
Mesoware · finsmes.com · Jun 9, 2026
Catena Labs · thesaasnews.com · May 27, 2026
Shimmer · ycombinator.com · Jan 15, 2026
Edison Scientific · techfundingnews.com · Dec 19, 2025
Hometap · finance.yahoo.com · Dec 9, 2025
Frequently asked questions
- How many investments has Pillar VC made?
- Pillar VC has 120 tracked investments, 3 of which have exited, including 19 dated in the last 24 months.
- What stage does Pillar VC invest at?
- Pillar VC invests at the Pre-Seed, Seed, Series A stages.
- What is Pillar VC's typical check size?
- Pillar VC typically writes checks of $50K – $4M.
- What sectors does Pillar VC focus on?
- Pillar VC focuses on AI & Machine Learning, Biotech, Deep Tech, Digital Health, Enterprise Software, Healthtech, Medical Devices.
- Where is Pillar VC located?
- Pillar VC is headquartered in Boston, US.
- Does Pillar VC lead rounds?
- Yes, Pillar VC leads investment rounds.
- Who does Pillar VC co-invest with?
- Pillar VC most often shares deals with Andreessen Horowitz, Founder Collective, Wing, among 278 tracked co-investors.
Media · Podcasts & interviews
featuring the teamImages
Co-investors · 36
Andreessen Horowitz (a16z) is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, known for pioneering the platform model with a large team of operators supporting founders across stages.
General Catalyst is a venture capital firm operating as a partnership focused on company building and accelerating the growth of the businesses it backs.
Founder Collective is a seed and pre-seed stage venture capital firm that invests across sectors, describing itself as sector agnostic and anti-thematic.
Spark Capital is a venture capital firm that partners with founders, known for early investments including leading Twitter's Series B in 2008.
Union Square Ventures is a New York-based venture capital firm that invests across a broad range of technology sectors, presenting a large portfolio spanning crypto, fintech, climate, AI, education, health, and marketplaces.
Lightspeed Venture Partners is a global venture capital firm that backs founders from Seed through Series F and beyond, emphasizing deep, immersive partnerships with the companies it invests in.
Accel is a venture capital firm that partners with exceptional teams, positioning itself as a first partner to founders globally.
Threshold Ventures is a venture capital firm that partners with founder-led companies at inflection points of breakout growth, engaging early and providing hands-on advice during moments of market transformation.
Breakthrough Energy, founded by Bill Gates, backs innovators developing affordable, reliable, and clean energy technologies, investing across manufacturing, electricity, agriculture, transportation, and buildings.
Construct Capital is a venture capital firm that invests in companies transforming foundational industries such as supply chain, manufacturing, critical infrastructure, energy transition, and core software.
First Star Ventures is a pre-seed fund that backs technical, research-driven founders building companies at the intersection of computing, robotics, biology, and AI.
Galaxy Interactive originated as the interactive content and technology arm of crypto firm Galaxy Digital, giving it an unusual combination of deep crypto-native infrastructure knowledge and a pure-play focus on interactive media, gaming, and virtual worlds, rather than being a generalist crypto or generalist gaming fund. The fund leverages Galaxy's broader balance sheet and ecosystem—including trading, investment banking, tokenization, and infrastructure—to offer portfolio companies access to liquidity, tokenization expertise, and institutional crypto relationships, creating an integrated platform that is rare among sector-specific gaming and interactive VCs.
▶24 more co-investors
Bessemer Venture PartnersBain Capital VenturesSOSVAtlas VentureGlobal Founders CapitalDigital Currency GroupG20 VenturesJAZZ Venture PartnersGlasswing VenturesAt One VenturesAmerican Family VenturesPolaris PartnersHustle FundTCV83NorthPolychain CapitalXtripe AngelscLabsTrucks VCLife BiosciencesPrimitive VenturesFactionAllegoryBroadview Ventures
Firms observed investing alongside Pillar VC, from public investor directories. Shared companies are the overlap with Pillar VC's recorded portfolio.
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Khosla Ventures is a venture capital firm that backs bold, early-stage, technology-driven companies across deep tech and other sectors, providing hands-on 'venture assistance' to help founders build category-defining businesses.
OMERS Ventures is a venture capital firm that invests in founders globally, with investment teams based in New York, Palo Alto, and Toronto.
Colle Capital Partners is an opportunistic, early-stage technology venture fund investing globally across a broad range of technology sectors.
























































































































































































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