/People

James N. Topper

Investor

Managing Partner at Frazier Life Sciences

Palo Alto

Midas 2016 · #91

Find your path to James

Sign up to see every warm intro you have to James

  • Paths you didn't know you had: your email and LinkedIn already hold routes to James. We find them for you
  • 2nd- and 3rd-degree connections: the friend-of-a-friend routes that take hours to manually find through your inbox or LinkedIn
  • Answers now, not in days: momentum is everything in a raise. Skip asking around whether someone knows someone

Days of research, done the moment you sign in, with every route ranked by how warm it is.

About

James (Jamie) Topper co-leads Frazier's Life Sciences team as a Managing Partner, having joined the firm in 2003 and opened its first California office. Over more than two decades there, he has led or co-led investments in over 60 therapeutics-focused companies. Before joining Frazier, he headed cardiovascular R&D at Millennium Pharmaceuticals and served as VP of Biology at COR Therapeutics, and previously held faculty positions at Stanford and Harvard Medical School. He earned an M.D. and Ph.D. in Biophysics from Stanford and a B.S. from the University of Michigan.

Contact· self-published, not guessed

Invests in

Biotech

Deals · 14

AtterocorBoard seat

via Frazier Life Sciences · filed Dec 2017 · $59.1M raise

AlcrestaBoard seat

via Frazier Life Sciences · filed Oct 2016 · $50.9M raise

AptinyxBoard seat

via Frazier Life Sciences · filed May 2016 · $65M raise

Merganser BiotechBoard seat

via Frazier Life Sciences · filed Apr 2016 · $17.1M raise

Allena PharmaceuticalsBoard seat

via Frazier Life Sciences · filed Dec 2015 · $53M raise

AnaptysBioBoard seat

via Frazier Life Sciences · filed Jul 2015 · $40.8M raise

ChanRxBoard seat

via Frazier Life Sciences · filed Feb 2015 · $31.9M raise

Alpine Immune SciencesLed round

via Frazier Life Sciences · filed Sep 2021

AlnaraLed round

via Frazier Life Sciences

CoTherixLed round

via Frazier Life Sciences

InclineLed round

via Frazier Life Sciences

MavupharmaLed round

via Frazier Life Sciences

PortolaLed round

via Frazier Life Sciences

RempexLed round

via Frazier Life Sciences

Attribution from SEC filings, press coverage, and firm rosters.

Other disclosed investments

Led

Acerta Pharma BVCalistoga PharmaceuticalsThreshold

Board seats

Amunix PharmaceuticalsArchitect TherapeuticsAttovia TherapeuticsCounterakt TherapeuticsDiagonal TherapeuticsEnlaza TherapeuticsImmutrinNewAmsterdam PharmaPhathom Pharmaceuticals

Sources: the firm's website · SEC Form D filings.

Colleagues at Frazier Life Sciences

Frequently asked questions

Who is James N. Topper?
James (Jamie) Topper co-leads Frazier's Life Sciences team as a Managing Partner, having joined the firm in 2003 and opened its first California office. Over more than two decades there, he has led or co-led investments in over 60 therapeutics-focused companies. Before joining Frazier, he headed cardiovascular R&D at Millennium Pharmaceuticals and served as VP of Biology at COR Therapeutics, and previously held faculty positions at Stanford and Harvard Medical School. He earned an M.D. and Ph.D. in Biophysics from Stanford and a B.S. from the University of Michigan.
Where does James N. Topper work?
James N. Topper is Managing Partner at Frazier Life Sciences.
What does James N. Topper invest in?
James N. Topper invests in Biotech.
What boards does James N. Topper sit on?
James N. Topper holds tracked board seats at Alcresta, Allena Pharmaceuticals, Amunix Pharmaceuticals, AnaptysBio, AnaptysBio, Aptinyx, Architect Therapeutics, Atterocor, Attovia Therapeutics, ChanRx.
What companies has James N. Topper invested in?
Investments tracked here include Acerta Pharma BV, Alnara, Alpine Immune Sciences, Calistoga Pharmaceuticals, CoTherix, Incline, Mavupharma, Portola, Rempex, Threshold.
Does James N. Topper lead rounds?
Yes — James N. Topper has led 10 tracked investments.

About this profile. Compiled from public sources — Frazier Life Sciences's own website, regulatory filings and public professional profiles — and summarised by Fundraising Fox; every fact is kept with where it came from. Spotted an error, or would rather not be listed? Email privacy@fundraisingfox.com · How we build profiles · Your rights