/Companies

Theradaptive

Frederick, US · Delaware corporation · 3 known investors

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Theradaptive develops protein engineering technology that modifies recombinant proteins into material-binding variants for targeted therapeutic delivery, aiming to improve efficacy and reduce off-target effects. Its applications span more than a dozen clinical indications including spinal fusion, orthopedics, soft tissue repair, and targeted chemotherapeutics.

Founders & leadership

LALuis Alvarez
Luis AlvarezChief Executive Officer & FounderLuis Alvarez is the CEO and founder of Theradaptive, a biotech company developing therapeutics for tissue regeneration and repair, and previously led the Organ Manufacturing Group at United Therapeutics. He holds a PhD in Biological Engineering from MIT focused on protein engineering for targeted delivery of therapeutics via biomaterials, has more than 20 years of experience in bioengineering, cell biology, and regenerative medicine, and is an Army veteran.
DS
David StewartNamed on SEC filing
TA
Ted A. MeyersNamed on SEC filing
GS
George ShanineNamed on SEC filing
DH
David HarringtonNamed on SEC filing
JD
Jeffrey DunnNamed on SEC filing

Board

PZ
Patrick ZhangBoard MemberInvestor at Horizons Ventures

Investors · 3

Funding

SEC filings, press & company announcements

$36.2M disclosed across 1 of 4 rounds · 2021–2026

▶$36.2MraisedAug 2026 · 65 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Luis AlvarezExecutive Officer, Director
  • David StewartExecutive Officer, Director
  • Ted A. MeyersDirector
  • George ShanineDirector
  • Patrick ZhangDirector
  • David HarringtonDirector
  • Jeffrey DunnDirector
Offering amount
$77.9M
Amount sold
$36.2M
First sale
Jul 2026
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Related companies · 1

Companies working in the same space as Theradaptive.

Non-dilutive funding · 2 SBIR/STTR awards

Federal grants — no equity taken
AgencyPhaseYearAmount
Department of DefenseDefense Health ProgramPhase II2020$1.1M
Department of DefenseDefense Health ProgramPhase I2017$150K

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.

In the news

Frequently asked questions

What does Theradaptive do?
Theradaptive develops protein engineering technology that modifies recombinant proteins into material-binding variants for targeted therapeutic delivery, aiming to improve efficacy and reduce off-target effects. Its applications span more than a dozen clinical indications including spinal fusion, orthopedics, soft tissue repair, and targeted chemotherapeutics.
Who founded Theradaptive?
Theradaptive was founded by Luis Alvarez.
Who are Theradaptive's investors?
Theradaptive's investors include Horizons Ventures, Maryland TEDCO, TEDCO.
How much funding has Theradaptive raised?
Theradaptive has disclosed $36.2M raised across 1 of its 4 known rounds.
Where is Theradaptive headquartered?
Theradaptive is headquartered in Frederick, US.