/Companies

AOA Dx

also invests · investor profileYC S21

Denver, US · Founded 2020 · Delaware corporation · 25 employees · 45 known investors

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AOA Dx develops a blood-based liquid biopsy platform using mass spectrometry and machine learning to detect ovarian cancer at early stages through tumor-associated biomarkers in serum. The company serves oncologists and patients in women's health diagnostics.

Also known as AOA Dx Inc.

Founders & leadership· Y Combinator alumni (S21)

AOA Dx was founded in 2020 by Oriana Papin-Zoghbi, Alex Fisher, Anna Jeter, and Oriana Zoghbi-Harb.

OPOriana Papin-Zoghbi
Oriana Papin-ZoghbiCEO & Co-FounderOriana Papin-Zoghbi is CEO and co-founder of AOA Dx Inc., a company focused on women's health diagnostics.
AFAlex Fisher
Alex FisherCo-FounderAlex Fisher is Chief Operating Officer and Co-Founder of AOA Dx, a women's health company.
AJAnna Jeter
Anna JeterChief Regulatory Officer and Co-founderAnna Jeter is Chief Business Officer and co-founder of AOA Dx.
OZ
Oriana Zoghbi-HarbCo-founder
AMAbigail Mcelhinny
Abigail McelhinnyChief Scientific OfficerAbigail Mcelhinny is an executive with biotechnology experience in product development and operations, with expertise in companion diagnostics, regulated medical devices, and multi-omic technologies for tissue and plasma-based diagnostics. She leads AOA Dx, which develops a blood-based liquid biopsy platform for early detection of ovarian cancer.
RM
Rob MayersRecruiter

Board

SSSurbhi Sarna
Surbhi SarnaBoard directorCEO and Founder at Collate
JFJohn Friedman
John FriedmanBoard directorAdvisor at Good Growth Capital

Investors · 45

AlleyCorp✓ confirmed by AOA DxNew York · $1M – $5M

How we know: AlleyCorp's portfolio page · the company's own site · funding news · the VCSheet dataset · Y Combinator's founder network · Not right? Tell us

Astialisted by AstiaSilicon Valley

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FemHealth Ventureslisted by FemHealth VenturesShort Hills

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Kube VClisted by Kube VC

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LongeVClisted by LongeVCWashington D.C.

How we know: LongeVC's portfolio page · funding news · Y Combinator's founder network · Not right? Tell us

Olive Tree Capitallisted by Olive Tree CapitalBoston

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TBD Angelslisted by TBD AngelsNew York

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VU Venture Partnerslisted by VU Venture PartnersSan Francisco · $200K – $1M

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Catalytic Impact FoundationreportedHingham

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Coyote VenturesreportedSan Francisco

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Crista Galli VenturesreportedLondon

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Gore Range CapitalreportedSouthlake · $500K – $5M

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HelmreportedNew York City · $500K

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Laboratory Corporationreported

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Nexxus Holdingsreported

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Outward VCreportedLondon · $1.3M – $6.3M

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Oxford Angel FundreportedSan Francisco

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RH Capitalreported

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Rhia Venturesreported

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Tencent HoldingsreportedShenzhen

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Funding

SEC filings, press & company announcements

$38.7M disclosed across 5 of 7 rounds · 2021–2025

▶$8.1MraisedOct 2025 · 40 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Surbhi SarnaDirector
  • Anna Milik JeterExecutive Officer
  • Abigail McelhinnyExecutive Officer
  • Oriana Papin-ZoghbiExecutive Officer, Director
  • John FriedmanDirector
  • Alexander James FisherExecutive Officer
Offering amount
$30.6M
Amount sold
$8.1M
First sale
Oct 2025
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$1.8MraisedDec 2024 · 15 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Alexander James FisherExecutive Officer
  • Surbhi SarnaDirector
  • Anna Milik JeterExecutive Officer
  • John FriedmanDirector
  • Oriana Papin-ZoghbiExecutive Officer, Director
  • Abigail McelhinnyExecutive Officer
Offering amount
$7.5M
Amount sold
$1.8M
First sale
Dec 2024
Incorporated
Corporation, Delaware, 2020
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$23.6MraisedJul 2023 · 119 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Surbhi SarnaDirector
  • Anna Milik JeterExecutive Officer
  • Oriana Papin-ZoghbiExecutive Officer, Director
  • John FriedmanDirector
  • Alexander James FisherExecutive Officer
Offering amount
$24.2M
Amount sold
$23.6M
First sale
Jul 2023
Incorporated
Corporation, Delaware, 2020
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$2.6MraisedNov 2021 · 33 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Anna Milik JeterExecutive Officer, Director
  • Surbhi SarnaDirector
  • Alexander FisherExecutive Officer, Director
  • Oriana Zoghbi-HarbExecutive Officer, Director
Offering amount
$5M
Amount sold
$2.6M
First sale
Nov 2021
Incorporated
Corporation, Delaware, 2020
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$2.5MraisedJul 2021 · 38 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Anna Milik JeterExecutive Officer, Director
  • Alexander James FisherExecutive Officer, Director
  • Oriana Zoghbi-HarbExecutive Officer, Director
Offering amount
$2.5M
Amount sold
$2.5M
First sale
Feb 2021
Incorporated
Corporation, Delaware, 2020
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

The YC application· Summer 2021 batch

What they told YC

How long have each of you been working on this? How much of that has been full-time? Please explain.
The founders have worked on the project for two years. Following the exit of a prior startup, they evaluated more than 20 technologies from various countries before partnering with Prof. Uri Saragovi of McGill University, who developed a method for early ovarian cancer diagnosis. CEO Oriana has been full-time since September 2019, and the two other co-founders joined full-time in October 2020.
What is your company going to make? Please describe your product and what it does or will do.
The company is building a non-invasive blood-based liquid biopsy test to diagnose ovarian cancer at early stages. It addresses the fact that about 80% of cases are currently diagnosed at stages III and IV, where the five-year survival rate is 28%, compared with 90% for early-stage diagnosis, since existing methods lack sensitivity and specificity in stages I and II.

Summarized from the founders' answers on their Y Combinator profile.

Images

AOA Dx photo

Founder mafia

2 people who came through AOA Dx went on to found or lead other companies.

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Companies working in the same space as AOA Dx.

Legal entities · 1

corporate structure
AOA Dx Inc.

In the news

Frequently asked questions

What does AOA Dx do?
AOA Dx develops a blood-based liquid biopsy platform using mass spectrometry and machine learning to detect ovarian cancer at early stages through tumor-associated biomarkers in serum. The company serves oncologists and patients in women's health diagnostics.
Who founded AOA Dx?
AOA Dx was founded by Oriana Papin-Zoghbi, Alex Fisher, Anna Jeter, Oriana Zoghbi-Harb in 2020.
Who are AOA Dx's investors?
AOA Dx's investors include AlleyCorp, Good Growth Capital, Joyance Partners, Y Combinator, Astia, Aurum Venture Partners, Avestria Ventures, Bantam Group and 37 more.
How much funding has AOA Dx raised?
AOA Dx has disclosed $38.7M raised across 5 of its 7 known rounds.
Where is AOA Dx headquartered?
AOA Dx is headquartered in Denver, US.