Creative Destruction Lab (CDL) — Full Portfolio

1000 Kelvin is a research lab building physics-based AI foundation models for laser processes, predicting and controlling laser-material interactions such as thermal fields and melt pool formation to detect defects and optimize output.

Advanced ManufacturingAI & Machine LearningDeep Tech

2S Water manufactures AquaValid, a real-time water analyzer that continuously measures dissolved metals in process water using optical-emission spectroscopy technology.

CleantechClimate TechHardwareIoT

Co-investorsBUBURNT ISLAND VENTURESFOForesight CanadaSTStartup TNT

Kevin Sullivan(Founder)in

Co-investorsCOConcrete Ventures

4D Surgical develops imaging technology for image-guided surgical procedures.

HealthtechMedical Devices

Lorne Hofstetter, MD, PhD(Co-founder, CEO)inBlake Zimmerman, PhD(Co-Founder)

Co-investorsALAlso CapitalMYMythos Ventures Management, LlcINInflect Health

4pi Lab develops remote sensing satellites to detect, monitor, and respond to wildfires and their emissions for climate change mitigation.

AI & Machine LearningClimate TechDeep TechSpace Tech

SAStephen Achal(Chief Executive Officer, Chief Strategy Officer)inVTVictor Taylor(Chief Technology Officer)

Co-investorsSESeraphim Space

6Degrees is an Israel-based startup that develops digital accessibility solutions to help people with physical challenges gain independence, improve communication, and increase employability through enhanced digital access.

Digital HealthHardwareHealthtechImpact & Social GoodIoTMedical DevicesIsrael, IL

AKAryeh Katz(Co-founder)inMiri Berger(Co-founder)in

Co-investorsICIceland Venture StudioUNUnknown Group

AAZZUR provides a platform for creating and integrating financial services, including neo-banking solutions for startups, embedded finance for corporates, and banking-as-a-service infrastructure.

Cloud ComputingEnterprise SoftwareFintechSaaSBerlin, DE

PBPhilipp Buschmann(CEO)inMDMartin Damaske(COO/CFO)inLKLaura Kerturke(Head of Product)inRichard Unger(CTO)in

Co-investors181818 Venture CapitalALAlumni VenturesANAngels DenASastorya.vcBABasecamp FundGRGreat Stuff Ventures+3 more

Accelerate Wind develops edge-of-roof wind turbine technology for commercial and industrial customers globally, enabling local energy generation by harnessing wind channeled by building structures.

Advanced ManufacturingCleantechClimate TechEnergyHardwareSt. Louis, US

EBErika Boeing(Founder & CEO)inSSSophie Schaffer(Chief Operating Officer)inCWCharlie Walch(Chief Financial Officer)in

Co-investorsHAHalogen Ventures Management Company LlcINInnovation DepotTETechstarsTHThird DerivativeINInvested Development

Accipiter Biosciences uses computational protein design to develop de novo, single-agent protein therapies that engage multiple cell-surface receptors at once, functioning as agonists.

AI & Machine LearningBiotechDeep TechSeattle, US

MBMatthew Bick(Executive Officer, Director, Promoter)inJavier Castellanos(Executive Officer, Director, Promoter)inHector De Jesus Rincon Arano(Executive Officer, Promoter)Heather Redman(Director)Randall Schatzman(Director)William Canestaro(Executive Officer)in

Co-investorsFLFlying Fish VenturesARArgonautic VenturesCOColumbus Venture PartnersPAPack VenturesWRWRF Capital

Acerta provides an industrial AI analytics platform for discrete manufacturers to identify and resolve production defects early, reducing scrap, rework, and downtime.

Advanced ManufacturingAI & Machine LearningEnergyEnterprise SoftwareKitchener, CA

GCGreta Cutulenco(Founder)in

Co-investorsBDBDC Fund Investments (Fund-of-Funds)BDBDC Industrial Innovation Venture FundBDBDC Thrive Venture Fund for WomenBDBDC Venture CapitalGAGarage CapitalL-L-SPARK+7 more

Acorai develops a non-invasive, handheld heart monitor that estimates cardiac and pulmonary pressures (including PCWP and RAP) and hemodynamic congestion trends to help clinicians manage and personalize heart failure therapy.

AI & Machine LearningDigital HealthMedical Devices

Co-investorsCACapital Q® Ventures Inc.CACARMA FUNDMEMeridian Health VenturesSUSupermarket

Toronto-based Ada Support builds enterprise AI customer service agents that automate resolution across chat, email, voice and messaging.

David Hariri(Founder)inMike Murchison(Founder)in

Co-investors51515 VenturesACAccelBEBessemer Venture PartnersDMDMZDMDMZ VenturesFIFirstMark Capital+10 more

Adaviv offers an AI-based "Lean Cultivation Agent" that helps farms track crop health, team productivity, and work quality through mobile apps, computer vision, and WhatsApp/SMS-based insights.

AgTechAI & Machine LearningRoboticsSaaS

ISIan Seiferling(Co-founder & CEO)inMoe Vazifeh(Co-founder)Julian(COO)

Co-investorsDEDelta Emerald VenturesEMEmerging VenturesMIMilemark Capital PartnersNENew Stack VenturesREREMUS CapitalAIAiSprouts VC

Adept Materials develops advanced materials for building envelopes that improve energy efficiency, durability, and moisture management without sacrificing comfort.

Advanced ManufacturingCleantechConstruction TechDeep TechNew MaterialsSomerville, US

DSDerek Stein, Ph.D.(Founder & CEO)Derek Stein(Founder / Inventor)

BoardMiguel Galvez(Director)Daniel Cromie(Director)

Co-investorsANAnorak VenturesBABantam GroupSLSlater Technology FundTHThird Derivative

Adeptmind builds generative AI tools for retailers, offering AI-powered merchandising, product discovery, personalization, and marketing/ROAS optimization for e-commerce and omnichannel shopping.

AI & Machine LearningE-commerceRetail Tech

Jing He(Founder)inGWG Wu(Founder)in

Co-investorsDMDMZINInnospark VenturesNOnoa

AG Data Center builds modular, containerized edge data center infrastructure for deploying AI compute directly at remote sites such as hospitals, universities, utilities, and government facilities.

AI & Machine LearningCleantechClimate TechCloud ComputingData & InfrastructureIoTBeaverton, US

Buchanan Eugene Robert(Executive Officer)

Co-investorsTETechstars

Aegiq develops networked photonic quantum systems, including a quantum computer and photon sources, intended for practical large-scale deployment.

Deep TechHardwareQuantum ComputingSemiconductorsUK, GB

SDScott Dufferwiel(Founder)inMaksym Sich(Founder)

Co-investorsDEDeepbridge CapitalGIGIMIC Ventures

Affable BPM offers an AI-powered compliance platform for healthcare organizations, combining UniComply for monitoring regulations, policies, contracts, and audits with AffableFLOW for no-code workflow automation and an AI-driven compliance training LMS.

AI & Machine LearningHealthtechSaaS

Co-investorsSYSybilla Masters

Agnostiq (now part of DataRobot) provides an agent workforce platform for building, operating, and governing enterprise AI agents, including tools like Covalent for orchestrating compute to deploy agents across edge, cloud, or on-prem environments.

AI & Machine LearningCloud ComputingEnterprise Software

Co-investorsDIDifferential VenturesGRGreen Egg VenturesSCScout VenturesSCScout VenturesBOBoost VCTETensility Venture Partners

ai-coustics provides an audio reliability layer with speech technology such as Voice Focus, which removes background noise and other voices to improve transcription accuracy and keep voice agents responsive in noisy environments.

AI & Machine LearningDeep TechDeveloper ToolsSan Francisco, US

Arne Corvin Jaedicke(Executive Officer, Director, Promoter)Fabian Helmut Seipel(Co-founder & CEO)CJCorvin Jaedicke(Founder)inFabian Seipel(Founder)

BoardBGBORIS GOLDEN(Director)inSTSitar Teli(Director)in

Co-investorsINInovia CapitalACAcurio VenturesCOConnect VenturesCOConnect VenturesPAPartech VenturesFOFOV Ventures

Avalo uses machine learning to accelerate crop breeding, developing improved plant varieties such as fast-maturing broccoli, adaptive sugarcane, heat-resilient tomatoes, and low-input cotton.

AgTechAI & Machine LearningBiotechClimate TechDurham, US

MAMariano Alvarez(Founder)inBrendan Collins(Founder)

BoardLMLaurie Menoud(Director)in

Co-investorsATAt One VenturesBEBetter Ventures Central LlcBLBlue Bear Capital PartnersGEGermin8 VenturesGIGiant Ventures Global LlpGRGreycroft+1 more

AiDEN provides an automotive software platform that runs natively on vehicle infotainment screens, using real-time vehicle data to deliver contextual services, automate workflows, and unify fragmented in-car experiences.

AI & Machine LearningMobility & TransportationSaaS

Co-investorsBABand of AngelsBLBlu Venture InvestorsRSRSCM

Aitiologic is a molecular diagnostics and precision medicine company that uses AI-powered bioinformatics to translate disease biology into clinical insight.

AI & Machine LearningBiotechDigital HealthMedical DevicesVienna, AT

APAndreas Posch(Founder)inRERebecca Ertl(Chief Medical Officer)in

Co-investorsPUPUSH Ventures

Alan provides health insurance, provident insurance (prévoyance) and prevention services for self-employed individuals, companies of all sizes, retirees, and public-sector workers, combining coverage with a digital app for reimbursements, telehealth consultations (Clinique Alan), and wellness features.

Digital HealthHealthtechHR TechInsurTechParis, FR

CGCharles Gorintin(Founder)inJean-Charles Samuelian-Werve(Founder)inJean-Charles Samuelian(Founder)

Co-investorsAGAgoranovCOCoatue ManagementINIndex VenturesKIKima VenturesOROriginsPAPartech Ventures+13 more

Premier marketplace connecting companies with top sales and business development talent in the United States.

Co-investorsCACardinia VenturesSTStartX

ALAViDA Substance Use is a digital care program for substance use, offering 24/7 access via any device to a specialized care team and clinically-validated activities.

Digital HealthMental HealthWellness & Fitness

Co-investorsPAPallasite VenturesNINimbus Synergies Inc.

Albus Health develops clinically validated monitoring technology that tracks respiratory metrics, heart rate, and cough frequency to support clinical studies.

BiotechDigital HealthHealthtechMedical Devices

PMProf Maarten De Vos(Head of R&D)

Co-investorsMEMeridian Health VenturesPAParkwalk AdvisorsUCUCeed Funds

Alexi builds private cloud AI infrastructure for law firms, enabling intelligent systems that connect knowledge, workflows, and data while maintaining client control and security.

AI & Machine LearningEnterprise SoftwareLegalTechToronto, CA

MDMark Doble(CEO at Alexi)in

Co-investorsBEBeresford VenturesDRDraper AssociatesDRDrive CapitalFFFf Venture CapitalFOForefront VentureTETechstars+1 more

Allium manufactures stainless-clad rebar that meets the AASHTO M 329M standard, offered in a full size range (#3–#18) and ASTM A615 and A706 specifications.

Advanced ManufacturingCleantechConstruction TechNew MaterialsPeabody, US

Steven Jepeal(Cofounder)inSam McAlpine(Founder)in

Co-investorsAEAera VCALAlumni VenturesBABay Bridge Ventures ClimateCACastor VenturesPRPropeller VC

AlphaOne Robotics develops robotic systems for warehouse and logistics automation, specifically designed to automate truck unloading and palletizing operations.

AI & Machine LearningLogistics & Supply ChainRobotics

TCTim Criswell(Founder)inMMMatt Middleton(Founder)ACAlex Criswell(Founder)inSRSamarth Rajan(Founder)in

AQT develops quantum computers and quantum algorithms to solve complex problems across industries including aerospace, chemistry, materials science, and finance.

Cloud ComputingDeep TechHardwareQuantum ComputingInnsbruck, AT

TMThomas Monz(Co-Founder & CEO)inRBRainer BlattPeter Zoller

Develops alternative textile materials to replace polyester and reduce the fashion industry's plastic consumption and carbon emissions.

Advanced ManufacturingBiotechCircular EconomyClimate TechNew MaterialsToronto, CA

MAMyra Arshad(Founder)inAGAvneet Ghotra(Founder)in

Co-investorsAMAmplify CapitalBEBeresford VenturesCOCollaborative FundGAGarage CapitalITIT-Farm CorporationMAMaiora Rebel Ventures+5 more

Altay Therapeutics develops small molecule inhibitors targeting transcription factors to treat serious diseases including facioscapulohumeral muscular dystrophy and cancer.

BiotechDigital HealthHealthtechMedical DevicesSan Francisco, US

AOAli Ozes(Founder)inOOOsman Ozes(Founder)inJAMES BREITMEYER(Executive Officer, Director)ERIC BJERKHOLT(Director)MIKE GREY(Director)ESTER SKLARSKY(Director)

Co-investorsJUJude GomilaTATachyon VenturesY Y CombinatorFSFshd Global Research Foundation

Altiroenergy develops clean energy solutions, though the specific products or services are not detailed on the about page.

CleantechClimate TechEnergy

Samson Bowen-Bronet(Chief Executive Officer)Martin Aralov(Chief Technology Officer)Nic Pinkerton(Chief Operating Officer)

BoardProf. Jeff Bergthorson(Chief Scientific Advisor)

Co-investorsBOBoxOne VenturesHAHAXSOSOSVUCUCeed FundsUCUCeed

Altis Labs provides a web-based platform that applies AI models to medical imaging data to generate reproducible predictions and quantifications for clinical trials.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesToronto, CA

FBFelix Baldauf-Lenschen(Founder & CEO)inJohn(CTO)

Co-investorsDEDebiopharm Innovation FundFUFusionOROrbiMedBEBenchstrength Partners

Altrove uses machine learning and AI combined with crystal simulation, high-throughput lab experimentation, and materials characterization to discover, synthesize, and scale novel materials as substitutes for vulnerable existing materials.

Advanced ManufacturingAI & Machine LearningDeep TechEnterprise SoftwareNew MaterialsParis, FR

TMThibaud Martin(Founder)inJLJoonatan Laulainen(Founder)in

Co-investorsCOContrarian VenturesEMEmblemENEntrepreneur FirstALAlvenBPBpifranceFJFJ Labs

AlumaPower develops firm, dispatchable power technology aimed at addressing shortfalls in reliable 24/7 electricity for demand from AI data centers, re-industrialization, and electrification.

CleantechClimate TechEnergyHardwareSarnia, CA

Geoffrey Richard Steven Godwin(Director)RARob Alexander(Co-Founder & CEO)inHVHenk VandenEnde(Co-Founder & EVP, Business Development)inGeoff Sheerin(Inventor, Co-Founder & CTO)RGRichard Godwin(Co-Founder & Board Member)inPSPaul Simpson(Co-Founder & Board Member)in

Co-investorsBDBDC Fund Investments (Fund-of-Funds)BDBDC Venture CapitalE8E8 AngelsSTStarbridge Venture Capital LlcBIBioindustrial Innovation Canada

Ammobia develops a novel ammonia production process that operates at low pressure and low temperature, achieving record-setting conversion rates.

Advanced ManufacturingCleantechEnergySan Francisco, US

KBKaren Baert(Co-founder & CEO)inTGTristan Gilbert(Co-founder & CTO)in

Co-investorsCHChevron Technology VenturesSHShell VenturesAIAIR CapitalALAlumni VenturesCACastor VenturesCOCollaborative Fund+7 more

Amphitrite uses satellite data and artificial intelligence to provide ocean intelligence and forecasting services for maritime operators.

AI & Machine LearningClimate TechData & Infrastructure

ASAlexandre Stegner(CEO)inEMEvangelos Moschos(CTO)in

Co-investorsAGAgoranovATAtlantic

New York City, US

JCJason Cohen(Executive Officer, Director, Promoter)Lewis Cohen(Director)KGKarl Gemperli(Director)in

BoardNaoki Kamimaeda(Director)

Co-investorsBEBetter Food VenturesGLGlobal BrainSOSony Ventures CorporationTETechstarsBIBits x BitesHYHyperplane Venture Capital+1 more

Ananya Health develops a portable, battery-powered cryoablation platform for treating pre-cancerous cervical lesions at the point of care in any clinic setting.

FemTechHardwareHealthtechMedical DevicesSan Francisco, US

APAnu Parvatiyar(Cofounder & CEO)inWei-Hsiang Chang(Director)Allen Chang(CTO)Julie Yip(Cofounder & Lead Engineer)

Co-investorsDRDream Variation VenturesY Y CombinatorAGAgrolimen VenturesEHEHA Impact VenturesHAHarvard Management CompanyVEVenture Investment Associates+1 more

Angel City Bio is a physician-scientist founded pharmaceutical company developing bile-acid-based treatments for gastrointestinal diseases, with programs targeting indications such as GLP-1-associated gallbladder disease and Crohn's disease.

BiotechDigital Health

Anomaly Games is a studio that builds viral games and consumer apps for emerging platforms, using an in-house infrastructure stack and AI across design, content generation, and live operations.

AI & Machine LearningConsumerCrypto & Web3GamingNorth York

Long Do(Executive Officer, Director)

Co-investorsDEDecasonicTRTriptyq Capital

Antora manufactures thermal battery systems for long-duration energy storage, serving manufacturers and data centers seeking to tap into low-cost renewable power.

CleantechClimate TechEnergyEnterprise SoftwareFintechHardwareImpact & Social GoodNew MaterialsSunnyvale, US

APAndrew Ponec(Founder)inDBDavid Bierman(Founder)inJBJustin Briggs(Founder)inDavid Bierman, Ph.D.(Chief Commercial Officer, co-founder)Justin Briggs, Ph.D.(Chief Operating Officer, co-founder)AJAlfred Johnson(CEO & Co-Founder)

Co-investorsANAndreessen HorowitzBLBlackRockTETemasekBRBreakthrough Energy VenturesCOCongruent VenturesDEDeepwater Asset Management+24 more

AOA Dx develops a blood-based liquid biopsy platform using mass spectrometry and machine learning to detect ovarian cancer at early stages through tumor-associated biomarkers in serum.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesDenver, US

OPOriana Papin-Zoghbi(Founder)inAFAlex Fisher(COO)inAJAnna Jeter(Founder)inOriana Zoghbi-Harb(Executive Officer, Director)AMAbigail Mcelhinny(Executive Officer)inRob Mayers(Recruiter)

Co-investorsALAlleyCorpGOGood Growth CapitalJOJoyance PartnersY Y CombinatorASAstiaAUAurum Venture Partners+38 more

Aperture Bio develops technologies to translate human tumor biology in order to reduce risk in preclinical drug development.

AI & Machine LearningBiotechHealthtechAllston, US

Laura Kelley(Executive Officer, Director)Hannah Peterson(Executive Officer, Director)

Co-investorsGUGurtin VenturesTETechstars

Applikate Technologies is a hardware and software company that has built an automated histology platform with integrated digital imaging, which stains and images whole tissue samples without physical slicing to produce histopathology data in hours.

HardwareHealthtechMedical DevicesWashington, US

RTRichard Torres(Co-founder)inMLMichael Levene(Co-founder)inDavid Hint(Director)

Co-investorsBABalderton Capital

Aqua-Cell develops batteries for energy storage used to defer costly electricity substation upgrades, enable peak-load-shifting for factories and industrial facilities, and provide renewable self-sufficiency for microgrids and remote communities.

CleantechClimate TechEnergyHardwareKitchener, CA

KCKeith Cleland(Co-founder and CEO)inEBEllsworth Bell(Co-founder and CTO)in

Co-investorsSTStartup TNTWAWaterloo Accelerator Centre

Aquaai builds bio-inspired, fishlike underwater vehicles equipped with cameras and plug-and-play sensors to collect subsurface water data, offered on a Fish-as-a-Service model.

Climate TechDeep TechRobotics

LianeSimeon P.(Founder)in

Co-investorsADAd Astra VenturesBABackstage Capital

Aquacycl provides onsite industrial wastewater treatment using its patented technology to treat high-strength wastewater without dilution, offering energy-neutral operation, lower greenhouse gas emissions, and water reuse.

Circular EconomyCleantechClimate TechImpact & Social GoodEscondido, US

OBOrianna Bretschger(Executive Officer, Director)inMichael Jones(Director)Anil Jha(Director)

Co-investorsADAd Astra VenturesKEKeshif VenturesNENext Wave Impact808090 Industries

Aquarry develops technology solutions focused on mine closure and remediation.

CleantechClimate TechImpact & Social GoodNew Materials

KMKate Murphy, PhD(Founder)in

Co-investorsAVAvilaCOCollaborative FundDEDeep Science VenturesEVEvergreen Climate Innovations

Arda engineers plastic-free materials from spent grain sourced from brewers and distillers, using protein hierarchies and nontoxic chemistry.

Advanced ManufacturingBiotechCircular EconomyNew MaterialsLondon, GB

BCBrett Cotten(CEO)inETEdward TJ Mitchell(CTO)in

Co-investorsENEntrepreneur FirstGRGreen Angel VenturesOYOyster Bay Venture CapitalPLPlug and Play VenturesSASatganaSESerpentine Ventures+2 more

Areto Labs offers a responsible AI platform that combines human judgment with AI to detect and filter harmful online content such as hate speech and technology-facilitated gender-based violence, helping global brands and public figures build safer digital communities.

AI & Machine LearningCybersecuritySaaS

Lana(Co-founder)Kasey(Co-founder)JCJacqueline Comer(Co-founder)in

Co-investorsEDEdmonton UnlimitedSCScaleGood Fund LP (powered by TELUS)STStartup TNTTHThe 51 VenturesUCUCeed FundsUCUCeed+1 more

Argospace provides launch and transportation services for spacecraft and satellites beyond low Earth orbit (LEO), including cislunar and interplanetary missions.

Deep TechHardwareSpace TechEl Segundo, US

RCRyan Carlisle(Founder)inKCKirby Carlisle(Founder)inRCRobert Carlisle(Founder)in

Co-investorsAIAIR CapitalCRCrosslink CapitalEAEarthrise VenturesGAGaingelsHEHelios CapitalMAMana Ventures+5 more

Ariel Precision Medicine offers an AI-driven platform that integrates genomic and clinical data (including EHR/EMR records, lab results, and scientific literature) to produce peer-reviewed, evidence-based reports.

AI & Machine LearningBiotechDigital HealthPittsburgh, US

JGJessica Gibson(Executive Officer, Director)inDWDavid Whitcomb(Director)inJohn Moore(Executive Officer)

BoardSDStephan Dietrich(Director)inMary Del Brady(Executive Officer, Director)David Smith(Director)

Co-investorsSTString VenturesTHThe Robotics HubLELead Edge CapitalRORobotics Hub

ARIX combines robotics and data analytics to inspect and manage critical industrial assets.

AI & Machine LearningDeep TechEnergyIoTRoboticsJackson, US

DLDianna Liu(President and CEO)in

Co-investorsALAlleyCorpCOContour Venture PartnersDODorm RoomENEnergy Transition VenturesGAGaingelsINInnovation Catalyst+6 more

Arkangel connects medical science and artificial intelligence to help healthcare teams make faster clinical decisions and reduce documentation errors.

AI & Machine LearningDigital HealthEnterprise SoftwareHealthtech

Co-investorsBRBroom Ventures46468 Capital

Armilla AI is a managing general agent offering liability coverage, performance warranties, and risk assessments for AI systems.

AI & Machine LearningData & InfrastructureEnterprise SoftwareFintechInsurTechToronto, CA

DADan Adamson(Founder)inKRKarthik Ramakrishnan(Founder)inBaiju Hasmukhrai Devani(Executive Officer, Director)Baiju Devani(Founder)Rahm Hafiz

BoardRBRaif Barbaros(Director)in

Co-investorsBEBeresford VenturesBEBetaworksDIDifferential VenturesMIMistral Venture PartnersMSMS&AD VenturesRERebel Fund+8 more

Arolytics appears to work on emissions detection and monitoring, with a focus case study on methane emissions at oil and gas facilities.

AI & Machine LearningClimate TechEnergySaaS

Co-investorsACAccelerate FundBDBDC Sustainability Venture FundSTStartup TNTBDBDC Capital CorporationMEMetiquity VenturesYAYaletown Partners

Arrowsmith Genetics is a preclinical-stage drug discovery company developing therapeutics from genetic research conducted at UBC and BC Cancer.

BiotechDeep TechVancouver, CA

Phil HieterPSPeter Stirling(Founder)inNigel O'Neil(Founder)in

Co-investorsINInnovation UBC

Arylla produces invisible ink tags using nanotechnology that can be applied to fashion products and read via smartphone to enable authentication, traceability, and personalized customer experiences.

Advanced ManufacturingDirect to ConsumerIoTNew MaterialsRoboticsKitchener, CA

PEPerry Everett(Business Development)inBRBenjamin Rasera(Founder)inGTGraham Thomas(Founder)in

Co-investorsY Y CombinatorVTVTF CapitalAGAgrolimen VenturesOROriza HoldingsU-U-Start

AgTechIthaca, US

Frank Schroeder(Director)JFJay Farmer(Executive Officer, Director)in

BoardAlex Bondar(Director)inKWKyle Welborn(Director)in

Co-investorsACAcre Venture PartnersPOPonderosa VenturesCUCultivation Capital

Ashored develops fixed-gear fishing technology aimed at reducing marine animal entanglements caused by traditional buoy-and-rope trap systems.

Climate TechHardwareImpact & Social Good

Co-investorsINInnovative Solutions Canada

Aspero Medical develops the Pillar balloon overtube solution with micro-textured design to improve control and anchoring during balloon endoscopy for small bowel diagnosis and treatment.

Deep TechHealthtechMedical DevicesBoulder, US

MRMark Rentschler(Co-Founder, CEO)inSteven Edmundowicz, MD(Co-Founder, Chief Medical Officer)

BoardMFMike Freeman(Director)in

Co-investorsINInnosphere VenturesRORockies Venture Club

Asteroid Mining Corporation is an applied sciences firm focused on asteroid mining operations.

Deep TechSpace Tech

Asynchronics develops NeXosim, a simulation framework for space systems that enables high-fidelity modeling and validation of spacecraft and satellite hardware.

Deep TechDeveloper ToolsSpace Tech

ACAdam Chikha(Co-Founder & CEO)in

Co-investorsHEHeartfelt CapitalHEHEC Paris IncubatorSUSunfish PartnersSUSunfish Partners

Atlas Metrics provides an AI-powered platform that combines non-financial data from multiple sources to help financial institutions manage ESG, climate, and financial risks while automating regulatory reporting and compliance.

AI & Machine LearningClimate TechDeveloper ToolsFintechLondon, GB

Robert Stojnic(CEO)inRTRoss Taylor(CTO)inWladimir Nikoluk(Founder)in

Co-investorsB2b2ventureBEBerliner Volksbank VenturesCHCherry VenturesENEntrepreneur FirstKIKickstart InnovationRERedstone+7 more

Atmose builds instruments to measure and condition ultrafine aerosol particles in a range of field locations, addressing gaps in conventional air-quality measurement systems.

CleantechClimate TechHardwareEdmonton, CA

TJTyler Johnson(Founder)in

Co-investorsINInnovative Solutions Canada

Atomwise uses artificial intelligence and machine learning to discover novel small-molecule drugs, with a current focus on developing treatments for immune and inflammatory diseases.

AI & Machine LearningBiotechDeep TechSan Francisco, US

Izhar Wallach(Founder)inAHAbraham Heifets(Founder)inYZYan Zhao(Executive Officer)inStephen Worland(Executive Officer, Director)

BoardRMRobert Mittendorff(Director)inASAdam Seabrook(Director)in

Co-investorsAUAurum Venture PartnersB B Capital GroupCECerity Partners VenturesDRDraper AssociatesMIMission and MarketTHThreshold Ventures+7 more

Audette provides a platform for asset and portfolio managers to identify and prioritize building retrofit investments, using data analysis to uncover high-return opportunities that improve net operating income and reduce emissions.

PropTechSaaS

Co-investorsBUBuoyant Ventures Management, LlcENEnergy Impact PartnersFOForesight CanadaGAGaingelsMOModerne VenturesPAPanache Ventures+3 more

Audio Design Desk is a macOS application for sound design and music creation, offering AI-powered search across a library of 70,000+ royalty-free sound effects, loops, and music cues to build audio layers for video.

AI & Machine LearningCreator EconomyMedia & Entertainment

Co-investorsBEBeresford Ventures

Aufero Medical develops TruContact, an add-on accessory device that provides on-demand catheter stability during atrial fibrillation ablation procedures.

HardwareHealthtechMedical Devices

DGDaniel Gelman(Founder & CEO)MDMaria Drangova(Founder)ASAllan Skanes(Founder)

HealthtechNashville, US

STEPHEN KALINSKY(Executive Officer, Director)JMJared Meyers(Executive Officer, Director)inStephen Kalinksky(Executive Officer)

Aurora Hydrogen develops microwave-driven methane pyrolysis technology to produce low-cost clean hydrogen without CO₂ emissions.

CleantechClimate TechDeep TechEnergyNew MaterialsEdmonton, CA

Murray Thomsonin

Co-investorsENEnergy Innovation CapitalTHThird DerivativeCHChevron Technology VenturesSHShell Ventures

Autozen operates an online platform for selling used cars, connecting individual car sellers with buyers.

ConsumerMarketplacesMobility & Transportation

SMSean Mactavish(CEO)in

Co-investorsVAVanedge CapitalVAVanedge Capital Limited Partnership

AuX Labs uses precision fermentation to produce recombinant milk proteins, starting with casein, that replicate the functional performance of dairy without animals.

BiotechClimate TechFoodTech

Ted Jin(Founder)

Co-investorsALAlwyn CapitalBLBluestein VenturesCOCongruent VenturesNÀNàdarra VenturesNANatural Products CanadaNYNYA Ventures+2 more

Aview provides multimedia translation and dubbing services to help content creators and entertainers expand their audience internationally across social media platforms.

AI & Machine LearningCreator EconomyMarketing TechMedia & EntertainmentAncaster, CA

Co-investorsBOBoxOne VenturesTETechstars

Avokaado is a contract intelligence platform that converts documents into structured data and lets legal and business teams draft, manage, track, and analyze contracts in one workspace.

AI & Machine LearningLegalTechSaaS

Co-investorsPAParticleTETera Ventures

Avro Life Sciences develops platform technology for novel drug delivery through passive transdermal administration.

BiotechHealthtechMedical DevicesWaterloo, CA

SLShak Lakhani(Founder)inKSKeean Sarani(Founder)in

Co-investorsEMEmbark VenturesFIFifty YearsGAGarage CapitalHEHeuristic Capital PartnersJUJude GomilaUPUpHonest Capital+10 more

Awake Labs provides a digital platform combining smartwatch, mobile, and web dashboard technologies to measure stress in real-time for adults with intellectual or developmental disabilities.

AI & Machine LearningDigital HealthHealthtechIoTMental HealthWellness & FitnessToronto, CA

Co-investorsTETechstars

Axiom Therapeutics runs a drug discovery platform for covalent inhibitors, applying machine learning to speed up physics-based simulations.

BiotechLondon, GB

RGRyan Geiser(CEO)inCHChris Haggard(CTO)inSDSofia Dahoune(Director)RGRyan Geiser, PhD(Founder)in

Co-investorsENEntrepreneur FirstGAGaingelsLULunar VenturesPLPlug and Play VenturesSASamos InvestmentsTRTranspose Platform Management+2 more

Axoft is developing soft, tissue-mimicking neural implants and supporting bidirectional electronics that record and stimulate brain activity through a minimally-invasive burr-hole procedure.

AI & Machine LearningDeep TechMedical DevicesCambridge, US

PLPaul Le Floch(Executive Officer, Director)inTYTianyang Ye(Director)inRSRachel Sha(Director)in

BoardChia An Lee(Director)Benjamin Pless(Director)

Co-investorsALAlumni VenturesAMAmino CapitalARArcherman CapitalBLBlindspot Ventures Management CoCACastor VenturesSASafar Partners+4 more

Axonis Therapeutics is a biotechnology company developing small-molecule medicines that target KCC2, a mediator of inhibition in the brain, to treat neurological disorders such as epilepsy and pain.

BiotechDeep TechBoston, US

SVShane V. Hegarty(Chief Scientific Officer & Co-Founder)inJSJoanna Stanicka(Chief Executive Officer, President & Co-Founder)inJIJeff Imbaro(Chief Operating Officer)inTSTiasha Shafiq(Chief of Staff)in

BoardC.Corey . Goodman(Director)inJLJonathan Leff(Director)in

Co-investorsSOSofinnova VenturesVEvenBio PartnersMRMRL Ventures FundCICivilization Ventures Management, LlcHAHatteras Venture PartnersIAIaso Ventures+8 more

Félix Bélisle Dockrill(Founder)in

Co-investorsBABastien Family OfficeBDBDC Industrial Innovation Venture FundECEcofuel FundFRFront Row Ventures

Ayrton Energy develops a hydrogen storage and transport solution based on a proprietary liquid organic hydrogen carrier (LOHC) and electrochemistry, storing hydrogen as a liquid at ambient conditions so it can be moved using existing fuel infrastructure.

CleantechClimate TechEnergyCalgary, CA

Co-investorsBDBDC Climate Tech Fund IICLClean Energy VenturesFOForesight CanadaMAMaRSMAMaRS Investment Accelerator Fund (IAF)SOSOSV+6 more

Wellness & FitnessToronto, CA

Co-investorsTETechstars

Bairitone develops a wearable patch-based system that maps airway vibrations to detect sleep apnea obstruction causes without MRI, X-ray, or ultrasound.

Digital HealthHealthtechMedical DevicesHouston, US

OKOnur Kilic(Executive Officer, Director)inMeagan Pitcher(Executive Officer, Director)Brittain Cross(Executive Officer, Director)

Co-investorsGOGolden SeedsSOSouth Loop VenturesSUSupermoon Capital

BANIQL uses an atmospheric-pressure leaching process to convert nickel ore into battery-grade mixed hydroxide precipitate (MHP), with nickel sulfate and nickel metal in development, avoiding HPAL autoclaves and using far less energy.

CleantechClimate TechDeep TechNew Materials

EJEric Januar(Founder)inSeungwan KiminWHWilly Halim(Founder)inAristotle V.(Founder)in

Co-investors50500 GlobalBEBEENEXTGEGenesia VenturesA2A2D VenturesTHThird Derivative

BarrelWise makes the FS1, a device that lets cellar workers measure free SO₂ directly at wine barrels with results uploaded to a cloud database for winemakers and lab teams to analyze.

AgTechHardwareIoT

Co-investorsEMEmmertechAGAg Capital CanadaCOConexus Venture Capital