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Colleen Cuffaro
InvestorPartner at Canaan Partners · Growth Equity Investor at FTV Capital · Board director at Alphina Therapeutics · Board director at Arrakis Therapeutics
New Haven, Connecticut
Writes $250K – $20M checks · typically $10M
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About
Colleen Cuffaro is a healthcare investor at Canaan Partners focused on biopharma companies pursuing transformative, scalable drug technologies such as small molecules and antibodies. She led Canaan's investment in Arrakis Therapeutics and holds a background connected to Yale. Her investment interest centers on companies addressing unmet medical needs through broadly applicable and scalable approaches.
Contact· self-published, not guessed
Invests in
Biotech
Beyond investing
- Founded
- Cuffaro proposed and helped start the Canaan-Yale Fellowship program, which gives Yale medical and life science graduate students exposure to drug development and venture capital.
- Education
- Studied at Yale (PhD)
- Hobbies
- Cuffaro competes in Ironman triathlons and has trained up to 20 hours a week at the peak of her training.
From published sources — common ground for a warm intro.
Board director at Alphina Therapeutics
Intro paths
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Board director at Arrakis Therapeutics
Intro paths
In turn, Colleen can intro founders to Arrakis Therapeutics's investors below.
Arrakis Therapeutics's investors · 8
Co-founders at Arrakis Therapeutics
Deals · 2
Alphina TherapeuticsBoard seat
via Canaan Partners · filed Mar 2026 · $10M raise
Arrakis TherapeuticsBoard seat
via Canaan Partners · filed Apr 2019 · $75M raise
Attribution from SEC filings, press coverage, and firm rosters.
Other disclosed investments
Sources: the firm's website · SEC Form D filings.
Colleagues at Canaan Partners
Network4
Investors connected to Colleen in public investor directories — a warm-intro map.
Frequently asked questions
- Who is Colleen Cuffaro?
- Colleen Cuffaro is a healthcare investor at Canaan Partners focused on biopharma companies pursuing transformative, scalable drug technologies such as small molecules and antibodies. She led Canaan's investment in Arrakis Therapeutics and holds a background connected to Yale. Her investment interest centers on companies addressing unmet medical needs through broadly applicable and scalable approaches.
- Where does Colleen Cuffaro work?
- Colleen Cuffaro is Partner at Canaan Partners and Board director at Alphina Therapeutics and Board director at Arrakis Therapeutics.
- What does Colleen Cuffaro invest in?
- Colleen Cuffaro invests in Biotech.
- What check size does Colleen Cuffaro write?
- Colleen Cuffaro typically writes checks of $250K – $20M.
- What boards does Colleen Cuffaro sit on?
- Colleen Cuffaro holds tracked board seats at Alphina Therapeutics, Arrakis Therapeutics, Arrakis Therapeutics.
- What companies has Colleen Cuffaro invested in?
- Investments tracked here include Arrakis Therapeutics, Agomab Therapeutics, Alphina Therapeutics, Arrakis Therapeutics, CatalYm, Draig Therapeutics.
- Does Colleen Cuffaro lead rounds?
- Yes — Colleen Cuffaro has led 1 tracked investment.