Where does Colleen Cuffaro work?

Colleen Cuffaro is Partner at Canaan Partners and Founder at Alphina Therapeutics and Founder at Arrakis Therapeutics.

What does Colleen Cuffaro invest in?

Colleen Cuffaro invests in Biotech.

What check size does Colleen Cuffaro write?

Colleen Cuffaro typically writes checks of $250K – $20M.

What companies did Colleen Cuffaro found?

Colleen Cuffaro founded Alphina Therapeutics, Arrakis Therapeutics.

Does Colleen Cuffaro lead rounds?

Yes — Colleen Cuffaro has led 1 tracked investment.

Colleen Cuffaro

InvestorFounder

Partner at Canaan Partners · Board director at Alphina Therapeutics · Board director at Arrakis Therapeutics

New Haven, Connecticut

Writes $250K – $20M checks · typically $10M

FoundedAlphina Therapeutics Arrakis Therapeutics

About

Colleen Cuffaro is a healthcare investor at Canaan Partners focused on biopharma companies pursuing transformative, scalable drug technologies such as small molecules and antibodies. She led Canaan's investment in Arrakis Therapeutics and holds a background connected to Yale. Her investment interest centers on companies addressing unmet medical needs through broadly applicable and scalable approaches.

Invests in

Biotech

Board director at Alphina Therapeutics

Intro paths

→

In turn, Colleen can intro founders to Alphina Therapeutics's investors below.

Alphina Therapeutics's investors · 4

Canaan PartnersStamford · $500K – $20M checks · since 2026 Connecticut InnovationsNew Haven · $500K – $2M checks HighCape CapitalWestport OUP (Osage University Partners)Bala Cynwyd · $1M – $20M checks

Co-founders at Alphina Therapeutics

Barbara FoxExecutive Officer, Director

Nicholas J GalliExecutive Officer, Director

Ranjit BindraDirector

Kevin L. RakinExecutive Officer, Director

Stanley ChoyExecutive Officer

Board director at Arrakis Therapeutics

Intro paths

→

In turn, Colleen can intro founders to Arrakis Therapeutics's investors below.

Arrakis Therapeutics's investors · 8

Advent Life SciencesLondon · since 2017 Canaan PartnersStamford · $500K – $20M checks · since 2017 Nextech InvestZurich · $648K – $3.2M checks Osage University PartnersBala Cynwyd OUP (Osage University Partners)Bala Cynwyd · $1M – $20M checks Pfizer Venture Investments$5M – $20M checks Pfizer Ventures venBio PartnersSan Francisco

Co-founders at Arrakis Therapeutics

Michael GilmanExecutive Officer, Director

Mark DeLongCEO

David NeafusExecutive Officer

Russell C. PetterExecutive Officer

Deals · 2

Alphina TherapeuticsBoard seat

via Canaan Partners · filed Mar 2026 · $10M raise

Arrakis TherapeuticsBoard seat

via Canaan Partners · filed Apr 2019 · $75M raise

Attribution from SEC filings, press coverage, and firm rosters.

Colleagues at Canaan Partners

Antonio Lepore

Investor at Canaan Partners

Brendan Dickinson

General Partner at Canaan Partners

Brent Ahrens

General Partner at Canaan Partners

Dana Malman Warren

Investor at Canaan Partners

Deepak Kamra

General Partner at Canaan Partners

Evan Teiger

Investor at Canaan Partners

Felipe Ossio

Investor at Canaan Partners

Guy Russo

General Partner at Canaan Partners

Network4

Brendan Dickinson

General Partner at Canaan Partners

Brent Ahrens

General Partner at Canaan Partners

Deepak Kamra

General Partner at Canaan Partners

Guy Russo

General Partner at Canaan Partners

Investors connected to Colleen in public investor directories — a warm-intro map.

Frequently asked questions

Where does Colleen Cuffaro work?: Colleen Cuffaro is Partner at Canaan Partners and Founder at Alphina Therapeutics and Founder at Arrakis Therapeutics.
What does Colleen Cuffaro invest in?: Colleen Cuffaro invests in Biotech.
What check size does Colleen Cuffaro write?: Colleen Cuffaro typically writes checks of $250K – $20M.
What companies did Colleen Cuffaro found?: Colleen Cuffaro founded Alphina Therapeutics, Arrakis Therapeutics.
Does Colleen Cuffaro lead rounds?: Yes — Colleen Cuffaro has led 1 tracked investment.