New Rhein Healthcare Investors, LLC
Venture capitalPhiladelphia · Series B–Late Stage · 15 people tracked
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Investment thesis
New Rhein invests in life sciences using a private equity-style approach, focusing on later-stage, de-risked assets that already have proven clinical safety and efficacy. The firm views product development execution and strategic exits as the primary drivers of investment returns. Its aim is to advance products that deliver meaningful health benefits to patients and compelling economic value to payors, while generating capital gains through strategic exits. Operating as a trans-Atlantic platform, New Rhein leverages managing partners with complementary experience in R&D, commercialization, organizational capability building, and M&A to identify promising products, bring them to market, and drive exits benefiting investors.
Source: firm website, verified Sep 29, 2026.
Team · 15 people
from the firm's website & curated & public directoriesWhat they invest in
from 4 of 12 portfolio companiesBiotech ×4Healthtech ×3Medical Devices ×2Deep Tech ×1Digital Health ×1Longevity ×1
HQs:United States×3Belgium×1
Investments · 12 tracked
founders shown can be your intro pathBy year:2025 · 12023 · 12018 · 13 dated
Neuraptive is a biotechnology company staffed by professionals with expertise in research and development, manufacturing, and commercialization in the pharmaceutical industry.
BiotechDeep TechHealthtechMedical DevicesLouisville, US
David Jackson(Executive Officer, Director)Gino DiSciullo(Director)Randy Hubbell(Director)
Board seatGreg ParekhIvan Gergel· per SEC Form D
Co-investorsCentral Texas Angel Network
Alveus Therapeutics develops next-generation metabolic and obesity therapies, including its lead asset ALV-100 (in Phase 2) and a preclinical amylin pipeline of peptides, oral small molecules, and novel formats aimed at sustainable weight loss with better tolerability.
BiotechHealthtechLongevityPhiladelphia, US
Raj Kannan(Executive Officer, Director)
BoardClaudio Nessi(Director)inJan Van de Bossche(Director)inGarrett Ingram(Director)Gregory Parekh(Director)
Board seatIvan Gergel· per SEC Form D
Co-investorsAndera PartnersAvego BioScience CapitalGlobal BioAccess FundJeito CapitalSeroba Life SciencesAgent Capital+2 more
Irvine, CA based Alzheimer's drug company
BiotechWashington, US
Thomas N. Chase(Executive Officer, Director)Douglas Ingram(Executive Officer, Director)John M. Siebert(Executive Officer, Director)Kathleen Clarence-Smith(Executive Officer)
BoardNayan Greg Parekh(Director)John M. Reher(Director)in
Co-investorsAndera PartnersBrain Trust Accelerator Fund
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
AlveusAmerican Injectables Inc.Butterfly MedicalCorsair PharmaNovagali PharmaSAYVAA PharmaSofthaleTheranica
Portfolio news
latest coverage across their companiesAlveus Therapeutics · finsmes.com · Mar 2, 2026
Frequently asked questions
- How many investments has New Rhein Healthcare Investors, LLC made?
- New Rhein Healthcare Investors, LLC has 12 tracked investments, including 1 dated in the last 24 months.
- What stage does New Rhein Healthcare Investors, LLC invest at?
- New Rhein Healthcare Investors, LLC invests at the Series B, Growth, Late Stage stages.
- What sectors does New Rhein Healthcare Investors, LLC focus on?
- New Rhein Healthcare Investors, LLC focuses on Biotech, Digital Health, Healthtech, Medical Devices.
- Where is New Rhein Healthcare Investors, LLC located?
- New Rhein Healthcare Investors, LLC is headquartered in Philadelphia, US.
- Who does New Rhein Healthcare Investors, LLC co-invest with?
- New Rhein Healthcare Investors, LLC most often shares deals with Andera Partners, Advent Life Sciences, Avego BioScience Capital, among 13 tracked co-investors.
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