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XGEN Venture

Venture capitaloperating company · company profile

Milan · Pre-Seed–Series A · 21 people tracked

Also known as XGen Venture SGR

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Investment thesis

XGEN Venture specializes in early-stage investments in private research and development companies within the life sciences sector, aiming to build next-generation life science ventures. Established by the former Genextra team, the firm draws on over 15 years of experience in the startup process and in the discovery and development of novel solutions for high unmet medical needs. It is currently deploying capital from its first fund, XGEN Venture Life Science Fund, launched at the end of 2022, while continuing to advise Genextra's board of directors on managing its existing portfolio.

Source: firm website, verified Sep 27, 2026.

Stage
Pre-Seed–Series A
HQ
Milan, IT
Instruments
Equity
Founded
2021
AUM
$194.4M
Tracked investments
11

Team · 21 people

from the firm's website & public directories

Founder mafia

3 people who came through XGEN Venture went on to found or lead other companies.

What they invest in

from 7 of 11 portfolio companies

Biotech ×6Healthtech ×4Medical Devices ×4Deep Tech ×3Digital Health ×3FemTech ×1

HQs:Italy×2Germany×1Sweden×1

Investments · 11 tracked

founders shown can be your intro path
Genespiregenespire.com✓ verified

Genespire is a life sciences company backed by multiple venture capital investors including Sofinnova Partners, XGEN Venture, CDP Venture Capital, and Indaco Venture Partners.

BiotechDeep TechDigital HealthHealthtech

Dr. Lucia Faccio(Chief Executive Officer)inDr. Julianne Smith(Chief Development Officer)Dr. Simon Hawkins(VP Clinical Development)Dr. Smaragda Angelidou(Responsabile CMC)Dr. Mary Wang(Patient Engagement Director)Emanuela Balzo(VP of Finance)in

Co-investorsCDP Venture CapitalIndaco Venture PartnersSofinnova Partners

Gesynta Pharmagesynta.sein✓ verified

Gesynta Pharma is a pharmaceutical company developing non-hormonal, anti-inflammatory drug candidates that inhibit the mPGES-1 enzyme, with a lead program in endometriosis.

BiotechDigital HealthFemTechMedical DevicesStockholm, SE

Patric Stenberg(Founder)Gunilla Ekström(Founder)in

Co-investorsAmboy Street VenturesForeground CapitalHadean VenturesHealthCapIndustrifondenCatalyze Capital

Nanophoriananophoria.comin✓ verified

NanoPhoria is a life sciences company that raised an €83.5 million Series A round.

BiotechDeep TechMedical Devices

Daniele CatalucciinMichele IafiscoAlessio AlognaClaudio De Lucain

Co-investorsSofinnova PartnersCDP Venture CapitalEuropean Innovation Council Fund

Epilepsy GTxepilepsygtx.comin

EpilepsyGTx is a preclinical-stage biotech developing gene therapies for focal refractory epilepsy (FRE), with the aim of making patients seizure free.

BiotechDigital Health

Co-investorsAlbionVCMoonstone Venture CapitalUCL Technology FundBritish Business BankHealth Technology Holding (HTH)

iOncturaionctura.comin𝕏

iOnctura is a clinical-stage drug development company developing precision oral small-molecule therapies targeting the tumor-stroma-immune interface, with a pipeline including roginolisib and cambritaxestat in cancers such as uveal melanoma and pancreatic cancer.

BiotechDeep TechHealthtechMedical Devices

Catherine Pickering(Co-Founder & CEO)inLars van der Veen(Co-Founder & CSO)inMichael Lahn(CMO)inElizabeth Holt(CBO)inSteven Sciuto(CFO)inMichelle Tsai(COO)in

Co-investorsInkef3B Future Health FundM VenturesVI PartnersJohnson & Johnson Innovation – JJDC

Nouscomnouscom.com

Immunotherapy company developing NOUS-209 for the prevention of Lynch syndrome-associated cancers.

Co-investors5AM VenturesAndera PartnersAngelini VenturesCDP Venture CapitalIndaco Venture PartnersM Ventures+6 more

Page Therapeuticspagetherapeutics.comin

PAGE Therapeutics is an oncology drug development company developing compounds that disrupt cell-cell adhesion to dissolve circulating tumor cell (CTC) clusters and block cancer metastasis.

BiotechHealthtech

Nicola Aceto(Co-founder, Chief Science Officer)inChristoph Rochlitz(Co-founder & Chief Medical Officer)inProf. Dr. Med. Christoph Rochlitz(Co-founder, Chief Medical Officer)Daniele Scarinci(Chief Executive Officer / Executive Director)inKatharina Venturi(Chief Operating Officer)in

Co-investorsClaris Ventures

Protembisprotembis.cominMar 2024

Protembis is a German medical device company developing the ProtEmbo Cerebral Protection System, an intra-aortic filter device inserted via the left radial artery that shields the brain from embolic debris during transcatheter aortic valve replacement (TAVR) and other left-sided heart procedures.

HealthtechMedical DevicesAachen, DE

Karl von Mangoldt(Co-Chief Executive Officer)inConrad Rasmus(Co-Chief Executive Officer)inOliver Marseille(CTO)

Co-investorsEuropean Investment BankcoparionSeed Fonds AachenTechVision FondsTechVision Fund

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

AavantgardeAAVantgarde BioTes Pharma

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has XGEN Venture made?
XGEN Venture has 11 tracked investments.
What stage does XGEN Venture invest at?
XGEN Venture invests at the Pre-Seed, Seed, Series A stages.
What sectors does XGEN Venture focus on?
XGEN Venture focuses on Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
Where is XGEN Venture located?
XGEN Venture is headquartered in Milan, IT.
Who does XGEN Venture co-invest with?
XGEN Venture most often shares deals with Indaco Venture Partners, Sofinnova Partners, CDP Venture Capital, among 29 tracked co-investors.

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