Milan · Pre-Seed–Series A · 21 people tracked
Also known as XGen Venture SGR
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Investment thesis
XGEN Venture specializes in early-stage investments in private research and development companies within the life sciences sector, aiming to build next-generation life science ventures. Established by the former Genextra team, the firm draws on over 15 years of experience in the startup process and in the discovery and development of novel solutions for high unmet medical needs. It is currently deploying capital from its first fund, XGEN Venture Life Science Fund, launched at the end of 2022, while continuing to advise Genextra's board of directors on managing its existing portfolio.
Source: firm website, verified Sep 27, 2026.
Team · 21 people
from the firm's website & public directoriesFounder mafia
3 people who came through XGEN Venture went on to found or lead other companies.
What they invest in
from 7 of 11 portfolio companiesBiotech ×6Healthtech ×4Medical Devices ×4Deep Tech ×3Digital Health ×3FemTech ×1
HQs:Italy×2Germany×1Sweden×1
Investments · 11 tracked
founders shown can be your intro pathGenespire is a life sciences company backed by multiple venture capital investors including Sofinnova Partners, XGEN Venture, CDP Venture Capital, and Indaco Venture Partners.
BiotechDeep TechDigital HealthHealthtech
Dr. Lucia Faccio(Chief Executive Officer)inDr. Julianne Smith(Chief Development Officer)Dr. Simon Hawkins(VP Clinical Development)Dr. Smaragda Angelidou(Responsabile CMC)Dr. Mary Wang(Patient Engagement Director)Emanuela Balzo(VP of Finance)in
Co-investorsCDP Venture CapitalIndaco Venture PartnersSofinnova Partners
Gesynta Pharma is a pharmaceutical company developing non-hormonal, anti-inflammatory drug candidates that inhibit the mPGES-1 enzyme, with a lead program in endometriosis.
BiotechDigital HealthFemTechMedical DevicesStockholm, SE
Patric Stenberg(Founder)Gunilla Ekström(Founder)in
Co-investorsAmboy Street VenturesForeground CapitalHadean VenturesHealthCapIndustrifondenCatalyze Capital
NanoPhoria is a life sciences company that raised an €83.5 million Series A round.
BiotechDeep TechMedical Devices
Daniele CatalucciinMichele IafiscoAlessio AlognaClaudio De Lucain
Co-investorsSofinnova PartnersCDP Venture CapitalEuropean Innovation Council Fund
EpilepsyGTx is a preclinical-stage biotech developing gene therapies for focal refractory epilepsy (FRE), with the aim of making patients seizure free.
BiotechDigital Health
Co-investorsAlbionVCMoonstone Venture CapitalUCL Technology FundBritish Business BankHealth Technology Holding (HTH)
iOnctura is a clinical-stage drug development company developing precision oral small-molecule therapies targeting the tumor-stroma-immune interface, with a pipeline including roginolisib and cambritaxestat in cancers such as uveal melanoma and pancreatic cancer.
BiotechDeep TechHealthtechMedical Devices
Catherine Pickering(Co-Founder & CEO)inLars van der Veen(Co-Founder & CSO)inMichael Lahn(CMO)inElizabeth Holt(CBO)inSteven Sciuto(CFO)inMichelle Tsai(COO)in
Co-investorsInkef3B Future Health FundM VenturesVI PartnersJohnson & Johnson Innovation – JJDC
Immunotherapy company developing NOUS-209 for the prevention of Lynch syndrome-associated cancers.
Co-investors5AM VenturesAndera PartnersAngelini VenturesCDP Venture CapitalIndaco Venture PartnersM Ventures+6 more
PAGE Therapeutics is an oncology drug development company developing compounds that disrupt cell-cell adhesion to dissolve circulating tumor cell (CTC) clusters and block cancer metastasis.
BiotechHealthtech
Nicola Aceto(Co-founder, Chief Science Officer)inChristoph Rochlitz(Co-founder & Chief Medical Officer)inProf. Dr. Med. Christoph Rochlitz(Co-founder, Chief Medical Officer)Daniele Scarinci(Chief Executive Officer / Executive Director)inKatharina Venturi(Chief Operating Officer)in
Co-investorsClaris Ventures
Protembis is a German medical device company developing the ProtEmbo Cerebral Protection System, an intra-aortic filter device inserted via the left radial artery that shields the brain from embolic debris during transcatheter aortic valve replacement (TAVR) and other left-sided heart procedures.
HealthtechMedical DevicesAachen, DE
Karl von Mangoldt(Co-Chief Executive Officer)inConrad Rasmus(Co-Chief Executive Officer)inOliver Marseille(CTO)
Co-investorsEuropean Investment BankcoparionSeed Fonds AachenTechVision FondsTechVision Fund
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
AavantgardeAAVantgarde BioTes Pharma
Portfolio news
latest coverage across their companiesEpilepsy GTx · eu-startups.com · Dec 10, 2025
Frequently asked questions
- How many investments has XGEN Venture made?
- XGEN Venture has 11 tracked investments.
- What stage does XGEN Venture invest at?
- XGEN Venture invests at the Pre-Seed, Seed, Series A stages.
- What sectors does XGEN Venture focus on?
- XGEN Venture focuses on Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
- Where is XGEN Venture located?
- XGEN Venture is headquartered in Milan, IT.
- Who does XGEN Venture co-invest with?
- XGEN Venture most often shares deals with Indaco Venture Partners, Sofinnova Partners, CDP Venture Capital, among 29 tracked co-investors.
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