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XGEN Venture

Venture capital

Milan · Pre-Seed–Series A · 21 people tracked

Also known as XGen Venture SGR

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Investment thesis

XGEN Venture specializes in early-stage investments in private research and development companies within the life sciences sector, aiming to build next-generation life science ventures. Established by the former Genextra team, the firm draws on over 15 years of experience in the startup process and in the discovery and development of novel solutions for high unmet medical needs. It is currently deploying capital from its first fund, XGEN Venture Life Science Fund, launched at the end of 2022, while continuing to advise Genextra's board of directors on managing its existing portfolio.

Invests inBiotechDigital HealthHealthtechMedical DevicesEuropeGermanyItalyMilanNorth AmericaSwitzerland

Source: firm website, verified Aug 3, 2026.

Stage
Pre-Seed–Series A
HQ
Milan, IT
Instruments
Equity
Founded
2021
AUM
$194.4M
Tracked investments
13

Team · 21 people

from the firm's website & public directories

What they invest in

from 5 of 13 portfolio companies

Biotech ×4Healthtech ×4Deep Tech ×3Medical Devices ×3Digital Health ×1

HQs:Italy×2Germany×1

Investments · 13 tracked

founders shown can be your intro path
Genespiregenespire.com✓ verified

Genespire is a life sciences company backed by multiple venture capital investors including Sofinnova Partners, XGEN Venture, CDP Venture Capital, and Indaco Venture Partners.

BiotechDeep TechDigital HealthHealthtech

Dr. Lucia Faccio(Chief Executive Officer)Dr. Julianne Smith(Chief Development Officer)Dr. Simon Hawkins(VP Clinical Development)Dr. Smaragda Angelidou(Responsabile CMC)Dr. Albert Molina Gil(Associate Director CMC)Dr. Mary Wang(Patient Engagement Director)

Nanophoriananophoria.comin✓ verified

NanoPhoria is a life sciences company that raised an €83.5 million Series A round.

BiotechDeep TechMedical Devices

Daniele CatalucciMichele IafiscoAlessio AlognaClaudio De Luca

10 EpilepsyGTxepilepsygtx.com
Aavantgarde

Clinical-stage gene therapy company developing AAV therapeutics for inherited retinal disorders.

AAVantgarde Bioaavantgarde.com
Epilepsy GTx

Working to provide seizure freedom for patients with focal refractory epilepsy.

Gesynta Pharmagesynta.se
iOncturaionctura.comin𝕏

iOnctura is a clinical-stage drug development company developing precision oral small-molecule therapies targeting the tumor-stroma-immune interface, with a pipeline including roginolisib and cambritaxestat in cancers such as uveal melanoma and pancreatic cancer.

BiotechDeep TechHealthtechMedical Devices

Catherine Pickering(Co-Founder & CEO)Lars van der Veen(Co-Founder & CSO)Michael Lahn(CMO)Elizabeth Holt(CBO)Steven Sciuto(CFO)Michelle Tsai(COO)

Nouscomnouscom.com
Page Therapeutics

Oncology drug development company focused on metastasis prevention.

Pagetherapeuticspagetherapeutics.comin

PAGE Therapeutics is an oncology drug development company developing compounds that disrupt cell-cell adhesion to dissolve circulating tumor cell (CTC) clusters and block cancer metastasis.

BiotechHealthtech

Daniele Scarinci(CEO & Executive Director)Nicola Aceto(Co-founder & Chief Science Officer)Christoph Rochlitz(Co-founder & Chief Medical Officer)Katharina Venturi(Chief Operating Officer)

Protembisprotembis.comin

Protembis is a German medical device company developing the ProtEmbo Cerebral Protection System, an intra-aortic filter device inserted via the left radial artery that shields the brain from embolic debris during transcatheter aortic valve replacement (TAVR) and other left-sided heart procedures.

HealthtechMedical DevicesAachen, DE

Karl von Mangoldt(Co-Chief Executive Officer)Conrad Rasmus(Co-Chief Executive Officer)Oliver Marseille(CTO)

Tes Pharmatespharma.com

Frequently asked questions

What stage does XGEN Venture invest at?
XGEN Venture invests at the Pre-Seed, Seed, Series A stages.
What sectors does XGEN Venture focus on?
XGEN Venture focuses on Biotech, Digital Health, Healthtech, Medical Devices.
Where is XGEN Venture located?
XGEN Venture is headquartered in Milan, IT.

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