XGEN Venture
Venture capitalMilan · Pre-Seed–Series A · 21 people tracked
Also known as XGen Venture SGR
Investment thesis
XGEN Venture specializes in early-stage investments in private research and development companies within the life sciences sector, aiming to build next-generation life science ventures. Established by the former Genextra team, the firm draws on over 15 years of experience in the startup process and in the discovery and development of novel solutions for high unmet medical needs. It is currently deploying capital from its first fund, XGEN Venture Life Science Fund, launched at the end of 2022, while continuing to advise Genextra's board of directors on managing its existing portfolio.
Source: firm website, verified Aug 3, 2026.
Team · 21 people
from the firm's website & public directoriesWhat they invest in
from 5 of 13 portfolio companiesBiotech ×4Healthtech ×4Deep Tech ×3Medical Devices ×3Digital Health ×1
HQs:Italy×2Germany×1
Investments · 13 tracked
founders shown can be your intro pathGenespire is a life sciences company backed by multiple venture capital investors including Sofinnova Partners, XGEN Venture, CDP Venture Capital, and Indaco Venture Partners.
BiotechDeep TechDigital HealthHealthtech
Dr. Lucia Faccio(Chief Executive Officer)Dr. Julianne Smith(Chief Development Officer)Dr. Simon Hawkins(VP Clinical Development)Dr. Smaragda Angelidou(Responsabile CMC)Dr. Albert Molina Gil(Associate Director CMC)Dr. Mary Wang(Patient Engagement Director)
NanoPhoria is a life sciences company that raised an €83.5 million Series A round.
BiotechDeep TechMedical Devices
Daniele CatalucciMichele IafiscoAlessio AlognaClaudio De Luca
Clinical-stage gene therapy company developing AAV therapeutics for inherited retinal disorders.
Working to provide seizure freedom for patients with focal refractory epilepsy.
iOnctura is a clinical-stage drug development company developing precision oral small-molecule therapies targeting the tumor-stroma-immune interface, with a pipeline including roginolisib and cambritaxestat in cancers such as uveal melanoma and pancreatic cancer.
BiotechDeep TechHealthtechMedical Devices
Catherine Pickering(Co-Founder & CEO)Lars van der Veen(Co-Founder & CSO)Michael Lahn(CMO)Elizabeth Holt(CBO)Steven Sciuto(CFO)Michelle Tsai(COO)
Oncology drug development company focused on metastasis prevention.
PAGE Therapeutics is an oncology drug development company developing compounds that disrupt cell-cell adhesion to dissolve circulating tumor cell (CTC) clusters and block cancer metastasis.
BiotechHealthtech
Daniele Scarinci(CEO & Executive Director)Nicola Aceto(Co-founder & Chief Science Officer)Christoph Rochlitz(Co-founder & Chief Medical Officer)Katharina Venturi(Chief Operating Officer)
Protembis is a German medical device company developing the ProtEmbo Cerebral Protection System, an intra-aortic filter device inserted via the left radial artery that shields the brain from embolic debris during transcatheter aortic valve replacement (TAVR) and other left-sided heart procedures.
HealthtechMedical DevicesAachen, DE
Karl von Mangoldt(Co-Chief Executive Officer)Conrad Rasmus(Co-Chief Executive Officer)Oliver Marseille(CTO)
Frequently asked questions
- What stage does XGEN Venture invest at?
- XGEN Venture invests at the Pre-Seed, Seed, Series A stages.
- What sectors does XGEN Venture focus on?
- XGEN Venture focuses on Biotech, Digital Health, Healthtech, Medical Devices.
- Where is XGEN Venture located?
- XGEN Venture is headquartered in Milan, IT.
Similar investors
Amadeus Capital Partners is a UK-based deep tech venture capital firm founded in 1997 that invests from seed to growth stages across artificial intelligence, health, and sustainability-focused technologies.
B Capital Group is a global venture capital firm that backs founders from early to late stage, with dedicated stage-based funds and a portfolio spanning technology, healthcare, and energy and resilience sectors.
Breyer Capital is a venture capital firm that backs high-impact entrepreneurs, making strategic investments guided by founder passion and its network of experienced investors.
DCVC (Data Collective) is a venture capital firm that backs founders building companies which apply technology to major challenges across areas such as energy, biotech, agriculture, and machine learning.
Future Positive Capital is an investment firm backing entrepreneurs building companies that address major global challenges and shape more sustainable, preferable futures.




















