Pivotal Life Sciences — Full Portfolio

Avalyn Pharma develops inhaled therapies for pulmonary fibrosis, using a nebulization approach that delivers treatment directly to the lungs to reduce the tolerability problems of existing oral therapies.

BiotechHealthtech

LBLyn Baranowski(CEO)in

Co-investorsANAndera PartnersCACatalio Capital Management, LPF-F-Prime CapitalINInVivium CapitalNONorwest Venture PartnersRIRiverVest Venture Partners+9 more

Bolt Biotherapeutics is a clinical-stage biotech company developing novel immunotherapies that leverage innate immune system mechanisms to treat cancer.

BiotechHealthtechMedical DevicesSan Francisco, US

DEDr. Edgar G. Engleman(Founder)

Co-investorsPFPfizer Venture InvestmentsRARA CapitalSASamsara BioCapitalSOSofinnova VenturesVIVivo CapitalNANan Fung Life Sciences+3 more

Rallybio is a clinical-stage biotechnology company developing therapies for severe and rare diseases, with a lead program in RLYB116, a C5 complement inhibitor in clinical development, and a preclinical program in RLYB332, a matriptase-2 antibody for iron overload disorders.

HealthtechFarmington, US

Jeffrey M. Fryer(Executive Officer, Director)Martin W. Mackay(Executive Officer, Director)Stephen Uden(Executive Officer, Director)

Co-investors5A5AM VenturesCACanaan Partners

Rallybio is a clinical-stage biotech company developing therapies for people with severe and rare diseases, with a pipeline focused on complement dysregulation and hematology.

BiotechHealthtechNew Haven, US

SUStephen Uden(Founder)inMWMartin W. Mackay(Chairman of the Board of Directors)inJon(Chief Financial Officer)

Co-investors5A5AM VenturesCACanaan PartnersCOConnecticut InnovationsF-F-Prime CapitalMIMitsui Global InvestmentSOSolasta Ventures

Vaxcyte develops broad-spectrum vaccines to prevent bacterial infections, using a cell-free protein synthesis platform and synthetic chemistry techniques.

BiotechHealthtech

GPGrant Pickering(Founder)inGEGrant E. Pickering(Chief Executive Officer and Director)in

Co-investorsBIBioRock VenturesCTCTI Life Sciences Fund L.P.FOForesite CapitalFRFrazier Life SciencesLOLongitude CapitalRARA Capital+2 more

Engrail Therapeutics is a clinical-stage pharmaceutical company developing precision-targeted therapeutics for neupropsychiatric and neurodevelopmental disorders.

BiotechDigital HealthMedical DevicesSan Diego, US

Stephen(Co-founder, EVP Research & Development and Chief Development Officer)Paul Cayer(Chief Financial Officer)inVikram(President and Chief Executive Officer)Kimberly(Chief Scientific Officer)Quentin(Chief Technical Officer)

Co-investorsFOForesite CapitalLOLongwood FundNONorwest Venture PartnersRIRiverVest Venture PartnersYSYsios CapitalABabrdn plc+4 more

Gracell Biotechnologies develops cell therapy manufacturing platforms and treatments, with a focus on CAR-T cell therapies for cancer and autoimmune diseases.

BiotechHealthtechMedical DevicesSuzhou, CN

WWWilliam Wei Caoin

Co-investorsLALAVLILilly Asia VenturesOROrbiMedEXExome Asset ManagementJAJanus Henderson InvestorsRARA Capital+2 more

Plexium is a targeted protein degradation company developing small molecule therapeutics for treating diseases with high unmet medical needs using their proprietary DELTA Discovery platform.

AI & Machine LearningBiotechDeep TechSan Diego, US

Michael Martin, Ph.D.(Chief Executive Officer, President)JFJorge F. DiMartinoinMichael Martin(President, Chief Executive Officer)inSMStephen Mullennix(Executive Officer)in

BoardSMSerge Messerlian(Director)inCariad Chester(Director)in

Board seatRHRob Hopfner· per SEC Form D

Co-investorsCRCRV (Charles River Ventures)DCDCVC (Data Collective)M M VenturesNENeotribe VenturesSOSoftBank Vision FundTCTCG Crossover+2 more

Addition Therapeutics is a biotechnology company developing therapeutics, led by a scientific and clinical team.

BiotechHealthtechSouth San Francisco, US

KCKathleen Collins(Director)inLKLawrence Kong(Executive Officer)inRPRon Park(President & CEO)inFGFrancine Gregoire(Chief Scientific Officer)inPPPriya Parameswaran(Chief Business Officer)in

BoardJPJayson Punwani(Director)in

Co-investorsBEBEVCSRSR One Capital ManagementABAbingworthOSOsage University Partners

Akouos is a precision genetic medicine company developing therapies for the inner ear to restore, improve, and preserve hearing.

BiotechHealthtechBrookline, US

ESEmmanuel Simons(Executive Officer, Director)WSwilliam sewell(Founder)in

BoardEMEd Mathers(Director)inKPKush Parmar(Director)in

Co-investors5A5AM VenturesECEcoR1 CapitalNENew Enterprise Associates (NEA)RARA CapitalSOSofinnova VenturesCOCowen Healthcare Investments+1 more

HealthtechSaratoga Springs, US

DTDaniel T. Pickett III(Executive Officer, Director)Timothy Koehler(Executive Officer)Greg Stephen(Executive Officer)

BoardHolly Benson(Director)Mary Langowski(Director)Peter Dorsman(Director)

Co-investorsCLClaritas CapitalWHWhat If VenturesOLOlive Tree VenturesTATakeda VenturesVIVista Equity Partners

Ark provides a customizable digital platform for venture capital and private equity firms to manage investor communications, performance reporting, and document sharing with their limited partners.

Enterprise SoftwareFintechSaaS

Co-investorsACAcies InvestmentsALAloft VCALAlta PartnersAMAmity VenturesARArtis VenturesASAsymmetric Capital Partners+21 more

Arkuda is an independent information platform that provides analysis and reviews of online gaming platforms operating in Azerbaijan, focusing on legal compliance, security protocols, and user protection for gaming platforms like Mostbet.

ConsumerGamingBaku, AZ

Co-investorsATAtlas VentureMIMission BiocapitalPFPfizer Venture InvestmentsPFPfizer Ventures

DermBiont develops SM-030, a topical drug candidate targeting melasma, a skin pigmentation disorder, by inhibiting PKC-beta to address the underlying cause of hyperpigmentation.

BiotechDigital HealthMedical DevicesBoston, US

RBRobert Brucker(Executive Officer)inKRKarl R. Beutner(Executive Officer, Director)inNENichola Eliovits(Executive Officer, Director)inMDMax Dawson(Executive Officer)in

BoardWRWilder Ramsey(Director)inJennifer Lee(Director)

Co-investorsCICivilization Ventures Management, LlcJOJoyance PartnersOLOlive Tree CapitalSTStart CapitalTOToba CapitalVAValia Ventures+1 more

Evommune develops therapies targeting the underlying sources of chronic inflammatory diseases, aiming to provide underserved patient populations with more than symptomatic relief.

BiotechHealthtechPalo Alto, US

LPLuis Pena(Executive Officer, Director)inJanice Drew(Executive Officer)David Cohen(Director)Gregory Moss(Executive Officer)Eugene Bauer(Executive Officer, Director)Francois Beaubien(Director)

Co-investorsANAndera PartnersAVAvego BioScience CapitalB B Capital GroupB4B4 CapitalBEBeiersdorf Innovation FundFEFemHealth Ventures+3 more

BiotechBoston, US

ABAxel Bolte(Executive Officer, Director)inReinaldo Diaz(Director)Joseph Schlessinger(Executive Officer, Director)

BoardEdward Mathers(Director)RHRob Hopfner(Director)inMartin Edwards(Director)

Co-investorsLOLongitude CapitalNENew Enterprise Associates (NEA)SASanofi VenturesSOSofinnova Ventures

Mosanna is a pharmaceutical company developing a non-invasive nasal spray therapy for obstructive sleep apnea (OSA) that reactivates the body's natural airway reflex to keep the upper airway open during sleep.

BiotechDigital HealthHealthtechMedical Devices

Barbara(Regulatory Affairs & Quality Assurance leadership)Kevin(Pharmaceutical Development leadership)Pranav(Head of Finance & Operations)Ben(Executive / Board)

BoardDavid White(Sleep Medicine Advisor)

Co-investorsBRBroadview VenturesNONorwest Venture PartnersSUSupermoon CapitalHTHTGFINInkef

Oculis is a biopharmaceutical company developing pharmaceutical drug products, with a focus on ophthalmic and eye disease treatments.

BiotechHealthtechMedical DevicesBoston, CH

RSRiad Sherif(Chief Executive Officer)in

Co-investorsBABay City CapitalBRBrunnur Ventures GPVIVI PartnersBVBVCF

Windward delivers AI-powered operational intelligence for maritime security and commercial applications, fusing behavioral analytics and multi-sensor data to detect threats and opportunities.

AI & Machine LearningData & InfrastructureDefense TechTel Aviv

Amiad Daniel(Executive Officer, Director)MPMatan Peled(Director)in

BoardDov Gatmon(Director)Patrick Poon(Director)ESEden Shochat(Director)inTHThompson Hutton(Director)in

Co-investorsALAlephFTFTV CapitalTHThompson Hutton, LLCJAJanus Henderson InvestorsQIQiming Venture PartnersQUQuan Capital+3 more

Windward Bio is a clinical-stage biotechnology company developing long-acting monoclonal and bispecific antibodies for serious immunological conditions such as asthma, COPD, and dermatological diseases.

BiotechHealthtech

Co-investorsOROrbiMedQUQuan CapitalRARA CapitalSASanofi VenturesSRSR One Capital ManagementJAJanus Henderson Investors+3 more