Kyoto University Innovation Capital

RadioNano Therapeutics develops boron neutron capture therapy (BNCT), an advanced radiotherapy targeting cancer cells.

BiotechDeep TechHealthtechMedical DevicesKyoto, JP

MCMasatoshi Chiba(CEO)inHiroshi Kawai(CBO/COO)

Co-investorsJAJapan Science and Technology AgencyMIMitsubishi UFJ CapitalDBDBJ Capital

Orizuru Therapeutics develops cellular therapy products and regenerative medicine treatments utilizing iPS cell-related technology.

BiotechHealthtechMedical DevicesFujisawa, JP

Kenji Nonaka(代表取締役 (CEO))

Co-investorsSMSMBC Venture CapitalSUSumitomo Mitsui Trust BankJDJDRF T1D Fund

Kolagen Pharma develops and sells pharmaceuticals, medical devices, and research reagents, and manufactures cosmetics, focusing on collagen-based biomaterials for regenerative medicine.

BiotechHealthtechLongevityMedical DevicesKyoto, JP

Hiroshi Nose(代表取締役 (Representative Director))

Junji Adachi(Founder)in

Co-investorsCECelesta CapitalCECelesta CapitalDBDBJ CapitalMCMCP Asset ManagementMIMIRAI SOUZOUSHShizuoka Capital+2 more

ACT Genomics is a cancer genomics company that provides genomic testing solutions to support personalized cancer care and precision medicine for patients and clinicians.

BiotechDigital HealthHealthtechMedical Devices

Co-investorsUMUMC Capital

AlphaNavi Pharma is a pharmaceutical company developing new drugs (Nav channel inhibitors) for patients suffering from chronic pain and neurological disorders.

BiotechDigital HealthHealthtech京都市, JP

小山田義博YOYoshihiro Oyamada(Representative Director)

Co-investorsSHShinsei Capital Partners

The Audio Metaverse creates a bridge between physical and virtual spaces through audio, allowing users to own audio spaces as unique digital assets with exclusive access features.

Creator Economy

BTB Therapeutics develops a non-opioid analgesic aimed at addressing the opioid crisis, along with a pipeline of RNA-modifying compounds for rare genetic diseases and to enhance cancer immunotherapy.

BiotechHealthtechMedical DevicesEscondido, US

Masatoshi Hagiwara(Chief Scientific Officer, Director of the Board (founder of BTB Therapeutics Co., Ltd.))TKTakashi Kiyoizumi(CEO, Director of the Board)inKenneth W. Locke(Chief Development Officer)

Cancer therapeutics development (RNA regulation abnormalities).

Co-investorsNINippon Venture CapitalSHShinsei Capital PartnersSMSMBC Venture CapitalUTUTokyo Innovation Platform Co. Ltd.

Cleanhearing develops Sono, a patented technology aimed at treating tinnitus.

Digital HealthHardwareHealthtechMedical Devices

Gerald Neuwirth(Founder / Technical Lead)inLydia Mitchell(Head of Product & Operations)

BoardHidero Niioka

CONNEXX SYSTEMS is a Japanese startup developing energy-storage batteries and a networked storage system ("Power Net") that links distributed batteries and renewable sources like solar and wind into a unified energy network.

CleantechEnergyHardware

Co-investorsUNUniversal Materials Incubator

GraGreen develops improved crop varieties using genome editing and traditional breeding methods to reduce resource inputs and increase agricultural yields.

AgTechClimate TechNagoya, JP

MNMasaki Niwain

Co-investorsBEBeyond Next VenturesSESeiho Investment WorksSHShizuoka CapitalTETechstarsUTUTokyo Innovation Platform Co. Ltd.

Kanjin Therapeutics is a biotechnology startup developing treatments to restore kidney function and address chronic kidney diseases, using a strategy of targeting the liver.

BiotechDigital HealthHealthtechMedical Devices

Co-investorsBEBeyond Next Ventures

Kyoto Fusioneering develops fusion energy technology and related engineering solutions to enable carbon-neutral power generation and advanced chemical processes such as hydrogen production and carbon capture.

Climate TechDeep TechEnergyKyoto, JP

Taka Nagao(Founder)inSTShutaro Takeda, Ph.D.(Founder)in

Co-investorsCOCoral CapitalDBDBJ CapitalGLGlobal BrainJIJIC Venture Growth InvestmentsSUSumitomo Mitsui Trust nvestment Co. Ltd.TETechstars+3 more

Myoridge develops serum-free cell culture media and optimization services for cell cultivation and regenerative medicine applications.

BiotechHealthtechMedical DevicesJapan, JP

Co-investorsBEBeyond Next VenturesDIDiamond Edge Ventures

Perseus Proteomics develops and supplies research antibodies targeting nuclear receptors and transcription factors, along with ELISA kits and diagnostic assays, serving life sciences researchers and pharmaceutical development.

BiotechDeep TechHealthtechMedical Devices

Co-investorsDBDBJ CapitalNENewton BiocapitalNINippon Venture CapitalSMSMBC Venture Capital

Platform for high-throughput material property simulation based on quantum mechanics.

Cambridge, US

Toru Shiozaki(CEO and Co-Founder)

BoardGuanhua Chen(Director)Garnet Chan(Chief Visionary Advisor and Co-founder)

Co-investorsABAbies VenturesUTUTokyo Innovation Platform Co. Ltd.2X2xNEMEmbark Ventures

RegCell Biosciences is a biotechnology company developing regenerative cell therapies, leveraging expertise in cell and gene therapy, manufacturing, and immunology to advance therapeutic treatments.

BiotechDeep TechMedical Devices

Michael McCullar, PhD(Chief Executive Officer)James Ahlers(Chief Financial Officer)Marty Giedlin, PhD(Chief Technology Officer)Tony Hurley(Chief Technical Operations Officer)SKSteve Kanner, PhD(Chief Scientific Officer)

Co-investorsFAFast Track InitiativeGLGlobal BrainUTUTECMIMitsubishi UFJ Capital

Restore Vis is a life sciences company founded by a vitreoretinal surgeon and clinician scientist focused on addressing inflammation, aging, neurodegeneration and angiogenesis through translational research from drug discovery to clinical trials.

BiotechDigital HealthHealthtechMedical DevicesTokyo, JP

Dr. Rajendra S. Apte(Paul A. Cibis Distinguished Professor; Vice Chair of Innovation and Translation; Founder)Yusaku Katada MD, PhD(Co-founder, Representative Director and CEO/CMO)HMHikaru Miyazaki(Representative Director and COO)in

Co-investorsASAstellas Venture Management LLCDBDBJ CapitalJIJIC Venture Growth InvestmentsNINippon Venture CapitalOSOSAKA University Venture CapitalRERemiges Ventures, Inc.+3 more

Shinobi develops next-generation cell therapies using iPSC (induced pluripotent stem cell) research, genetic engineering, and clinical infrastructure.

AI & Machine LearningBiotechHealthtechMedical Devices

Co-investorsASAstellas Venture Management LLCF-F-Prime CapitalFAFast Track InitiativeJIJIC Venture Growth InvestmentsEQEQT Life Sciences

Koji Itoin

Co-investorsBEBeyond Next VenturesENEnergy & Environment InvestmentGLGlobal Brain

U-MAP is a University of Nagoya spin-off developing new thermal-management materials to address heat problems in electronic devices such as smartphones, PCs, electric vehicles, data centers, and 5G equipment.

Deep TechHardwareNew MaterialsNagoya, JP

Co-investorsGLGlobal BrainUNUntroD Capital

Viage Therapeutics is a neuroscience drug developer working on novel oral neurotherapeutics that target the gut-brain axis, including its lead clinical candidate DGX-001 for cognitive impairment in conditions such as Alzheimer's and Parkinson's disease.

BiotechDeep TechHealthtechSan Francisco Bay Area, US

Kousaku Ohinata, Ph.D.(Founder, Scientific Advisor)Titus Plattel(CEO & President)inBRBrian Rogers(Leadership Team)inNeil Schwartz(Leadership Team)inSujata Sankar(Leadership Team)inSteven King(Leadership Team)in

Co-investorsMIMiyako CapitalRDRDiscoveryRERemiges Ventures, Inc.

Advance Composite develops and manufactures advanced composite materials aimed at supporting industrial development while reducing environmental impact through energy and resource efficiency.

Advanced ManufacturingCleantechNew Materials

Junichi Hattori(代表取締役社長 (President & Representative Director))

Co-investorsENEnergy & Environment Investment

eSep Inc. develops and provides nanoceramics membrane separation technology and related equipment and systems for chemical processes and energy applications.

Advanced ManufacturingCleantechNew MaterialsKyoto, JP

Kenichi SawamuraKen-ichi SAWAMURA(Founder)in

Co-investorsGLGlobal BrainHIHiroshima Venture Capital Co. Ltd.KOKobe University Capital

EneCoat Technologies develops and manufactures perovskite solar cells (PSCs) and related materials.

CleantechEnergyNew MaterialsKyoto, JP

加藤尚哉 (Naoya Kato)(Representative Director / Executive Officer / CEO)堀内保 (Tamotsu Horiuchi)(Director / Executive Officer / CTO)

Co-investors1515th RockGLGlobal BrainMIMIRAI SOUZOUMOMonozukuri VenturesNINippon Venture Capital

Cuorips develops regenerative medicine products based on human iPS cell technology, including its heart muscle cell sheet "Heart®" (Rehart) for treating severe heart failure caused by ischemic cardiomyopathy, along with catheter-based therapies and compound drugs (YS series).

BiotechHealthtechMedical DevicesOsaka, JP

Takayuki Kusanagi(Representative Director, President & CEO)Tadayuki Tanimura(Director, Executive Vice President)Kazuyoshi Hirao(Director, Executive Vice President & Chief Business Officer)Yoshiki Sawa(Director, Chief Medical Science Officer)

Co-investorsNINippon Venture Capital

Sunlit Seedlings Co., Ltd. describes its SDGs initiatives and its fraud-prevention policy for managing public research funds, stating it operates and manages competitive research funding in line with guidelines for the administration and auditing of public research expenses at research institutions.

AgTechCircular EconomyClimate TechDeep TechImpact & Social Good

tiem factory Inc. develops, manufactures, and sells functional materials, specifically an aerogel called SUFA (Super Functional Air), a porous material over 90% air engineered for high flexibility and elasticity in transparent plate form.

CleantechDeep TechNew MaterialsIbaraki, JP

橘弘一郎(代表取締役社長 (President & CEO))倉田真弥(取締役 / 代表取締役 (Director / Representative Director))

Board川瀬昇(取締役 (Director))

Co-investorsUNUniversal Materials Incubator

Tokiwa Bio develops the Stealth-type RNA vector (SRV™), a non-integrating gene delivery vector that can introduce multiple or large genes into cells at high efficiency for gene therapy.

BiotechDeep TechMedical Devices

Toregem Biopharma is a Kyoto University spin-off developing a tooth-regeneration drug based on a humanized anti-USAG-1 antibody that aims to regrow teeth with a single injection.

BiotechDeep TechHealthtechMedical Devices京都 (Kyoto), JP

喜早 ほのか (Honoka Kihayashi)(代表取締役社長 (Representative Director and President))髙橋 克 (Katsu Takahashi)(取締役CTO (Director and CTO))髙谷 宗男 (Muneo Takaya)(取締役CBO (Director and CBO))喜ほ喜早 ほのか(Co-founder & CEO (代表取締役社長))髙克髙橋 克(Co-founder & CTO)髙宗髙谷 宗男(Co-founder & CBO)

Co-investorsASAstellas Venture Management LLC

FIMECS, Inc. is a Japanese drug discovery company researching and developing new pharmaceuticals based on targeted protein degradation mechanisms.

BiotechMedical DevicesFujisawa, JP

KGKanae Gamo(Founder)inKanae Kamo(代表取締役 CEO (Representative Director & CEO))

Co-investorsUTUTokyo Innovation Platform Co. Ltd.

Physiologas develops technology to innovate healthcare and improve patient and family wellbeing.

Digital HealthHealthtechMedical Devices

KMKazuyoshi MIYAWAKI(Founder)in

HoloBio is a Japanese molecular biology research company that studies the unique functions of region-specific plants, animals, and symbiotic microorganisms across Japan.

AgTechBiotechDeep TechFoodTechKyoto, JP

Masato Umeda(Representative Director & President (Founder))Toshihide Kobayashi(Director & Head of Research)Kinya Nakaoka(Director & Head of Corporate Planning)

Co-investorsGEGenesia Ventures

Melody International develops mobile fetal and maternal monitoring medical devices, including the "iCTG" cardiotocograph and the "Central i" central monitoring system for perinatal care.

Digital HealthFemTechHealthtechMedical DevicesTakamatsu, JP

Ichiro Matsubara(Representative Director / CEO)

Atsushi Alex Mazawa(Founder)in

Co-investorsBEBeyond Next VenturesGLGlobal Brain

Rege Nephro develops regenerative medicine therapies for kidney disease, focusing on nephron progenitor cell research and differentiation from iPS cells.

BiotechHealthtechMedical DevicesKyoto, JP

Co-investorsGLGlobal BrainNINippon Venture Capital

aceRNA Technologies develops therapies based on RNA technology, focusing on the discovery of new functions of miRNA to contribute to regenerative medicine and the creation of new drugs for diseases that currently lack treatments.

BiotechDeep TechHealthtechMedical DevicesTokyo, JP

須川史啓(代表取締役 (Representative Director / CEO))

Sakanotochu sells produce grown with low-environmental-impact farming methods, sourcing from roughly 300 farms mainly in western Japan, about 80% of them new-entry farmers.

AgTechDirect to ConsumerE-commerceFoodTechKyoto, JP

小野 邦彦(代表者 (Representative))KOKunihiko Ono(Founder)

AFI manufactures rapid microbial detection systems using flow cytometry and solid-phase cytometry technologies for quality control in pharmaceuticals, clinical diagnostics, cosmetics, food and beverage, and environmental testing.

HardwareHealthtechMedical DevicesTokyo, JP

Co-investorsOSOSAKA University Venture Capital

Arktus Therapeutics develops regenerative medicine treatments derived from iPS cells, initially focusing on knee joint diseases with plans to expand to additional organ systems.

BiotechHealthtechLongevityMedical DevicesKyoto, JP

大岩 智大Tomohiro Oiwa(Representative Director (CEO))大岩 智大 (Tomohiro Ooi)(代表取締役 (CEO))

BoardKoichi Nakayama(Outside Director / Professor, Saga University School of Medicine)Makoto Ikeya(Outside Director / Associate Professor, Kyoto University CiRA (iPS Cell Research Institute))

FLOSFIA develops power semiconductor devices based on corundum-structure gallium oxide (α-Ga₂O₃), a material originating from Kyoto University in Japan, using its proprietary water-based "MISTEPITAXY" mist deposition process to achieve lower loss than SiC at silicon-level cost.

CleantechDeep TechNew MaterialsSemiconductorsKyoto, JP

人羅俊実(創業者・取締役会長 (Founder & Chairman))四四戸孝(代表取締役社長 (President & CEO))

Co-investorsENEnergy & Environment InvestmentMIMiyako CapitalUTUTEC

KOALA Tech Inc. is a Kyushu University spinout commercializing organic semiconductor laser diode (OSLD) technology as laser light sources compatible with organic electronic device platforms, including OLED displays.

Deep TechHardwareSemiconductorsFukuoka, JP

安達千波矢(Founder (Kyushu University Professor))Chihaya Adachi(Co-founder (Kyushu University Professor))FBFatima Bencheikh(Representative Director, CEO & CTO)in

Co-investorsBEBeyond Next VenturesSOSony Ventures Corporation

Lang-8 operates language learning web services and mobile applications that connect learners to correct each other's language exercises, including platforms for peer-to-peer language correction and question-and-answer language learning.

ConsumerEdTechSaaSSocialTokyo, JP

Xi Yangyang

Co-investorsDGDG IncubationOPOpen Network LabZ Z Venture Capital

LegalOn Technologies develops AI-based products for corporate legal and other corporate functions, including contract review and management tools such as LegalForce and the LegalOn Cloud platform.

AI & Machine LearningEnterprise SoftwareLegalTechSaaSTokyo, JP

角望角田 望(代表取締役)NTNozomu Tsunoda(Founder)in

Co-investorsDIDIMENSIONSOSoftBank Vision Fund

LEP (株式会社LEP) develops applications based on its proprietary bioluminescent protein technology to illuminate homes and cities, pursuing agriculture, exhibition, and energy business lines.

AgTechBiotechCleantechConsumerEnergyTokyo, JP

高元 丈治(代表取締役CEO)永健永井 健治(取締役CTO)出村 拓(取締役CSO)

Luxonus develops photoacoustic (optical ultrasound) 3D imaging devices and services for visualizing blood and lymphatic vessels, building on technology from Japan's Cabinet Office ImPACT program.

Deep TechHealthtechMedical DevicesKawasaki, JP

SASadakazu Aiso(代表取締役 (Representative Director))TTTaro Terashi(COO)inYoshiharu Takahashi(Executive Officer, Sales & Marketing)in

BoardOKOsami Kono(Director)Tomokatsu Hongo(Director)inLiu Bingxian(Director)

Co-investorsKEKeio Innovation InitiativeMIMIRAI SOUZOU

Mitate Zepto Technica develops specialized semiconductor and computing hardware for genome analysis, including custom processors, accelerator boards, and supercomputers that perform genomic sequencing at significantly higher speeds and lower costs than conventional systems.

BiotechDeep TechHardwareMedical DevicesSemiconductorsTokyo, JP

原島 圭介(代表取締役社長 (CEO))久保江 勝二(代表取締役会長 (Chairman))

Co-investorsMOMonozukuri Ventures

OOYOO develops membrane and gas separation technologies for industrial CO₂ capture from exhaust gases and CO₂ utilization in circular economy applications.

CleantechClimate TechNew MaterialsTokyo, JP

ESEASAN SIVANIAH(Founder)inESEasan Sivaniah(Founder)in

Co-investorsENEnergy & Environment InvestmentUTUTokyo Innovation Platform Co. Ltd.

OPTMASS develops transparent solar cells and infrared light-harvesting technology for buildings to generate and distribute electricity on-site.

CleantechEnergyNew MaterialsUji, JP

Masanori Sakamoto(Representative Director / CEO)

Co-investorsSASamurai IncubateUNUntroD Capital

TSK is a Japanese company established in 2021, led by chemistry PhDs with backgrounds in chemical industry, display manufacturing, and academic chemistry research.

AgTechCleantechClimate TechDeep TechNew Materials京都, JP

Eunchul Son(代表取締役 (Representative Director / CEO))孫 恩喆(代表取締役 (Representative Director))

BoardMasaharu Nakamura(取締役 (Director))

xCARE operates a talent platform and project management service specialized for the medical industry, connecting external professional experts with pharmaceutical, medical device, and other medical product development projects.

B2B MarketplacesEnterprise SoftwareFuture of WorkHealthtechMedical DevicesTokyo, JP

ATAtsushi Tanase(Founder)in

Yaqumo develops neutral atom quantum computers designed to solve complex computational problems across materials, chemicals, pharmaceuticals, and finance sectors.

Deep TechHardwareQuantum ComputingTokyo, JP

Kazuhiro Nakakoji

Co-investorsBEBeyond Next VenturesJIJIC Venture Growth InvestmentsQUQuantonation

YStory develops AI-powered digital health solutions for women, with a focus on menopause management.

AI & Machine LearningDigital HealthHealthtechTokyo, JP

JYJanet Yu(CEO (Representative Director))Sherry Shi(CEO (Representative Director))

Co-investorsSESeiho Investment Works

Ocean Eyes is a technology venture that uses pattern recognition, ocean simulation, and data assimilation to provide fishing-ground and ocean-condition forecasting services for fishers, aimed at sustainable use of marine resources.

AgTechAI & Machine LearningClimate TechData & InfrastructureKyoto, JP

Yusuke Tanaka(代表取締役 (Representative Director / CEO))田中裕介(代表取締役 (CEO))

BoardMasaaki Iiyama(取締役 (Director))Shuichi Kasahara(取締役 (Director))

Oligogen is a Japanese biotech venture focused on regenerative medicine and drug discovery, conducting novel research and development in the pharmaceutical field.

BiotechHealthtechMedical DevicesKyoto, JP

Kino Pharma is a Japan-based company with a Tokyo headquarters and a Kyoto research laboratory.

BiotechMedical DevicesKyoto, JP

Masatoshi Hagiwara(Founding Researcher)

Co-investorsOIOita Venture Capital

Questetra provides a workflow and business process management platform.

Cloud ComputingEnterprise SoftwareSaaS

Saki Corporation develops automated inspection systems for electronic modules, using image capture to automatically judge good versus defective products on electronic boards and power semiconductors.

Advanced ManufacturingHardwareRoboticsSemiconductorsTokyo, JP