2Flo Ventures
Venture capitalChicago · Pre-Seed–Seed · 57 people tracked
Investment thesis
2Flo Ventures invests in healthcare and life science solutions aimed at improving quality of life, expanding access to care, and advancing safe and effective treatments. The firm backs determined entrepreneurs tackling large unmet medical needs, combining decades of experience across healthcare and entrepreneurship to support and grow its portfolio of life science companies.
Source: firm website, verified Aug 3, 2026.
Team · 57 people
from the firm's website
A physician leader with expertise in clinical development, health equity, and healthcare innovation.
Founder of Plowshares Asset Management, a private company focused on strategic healthcare investments.
An active healthcare advisor and investor with over 25 years of experience as a primary care physician and health IT innovator.
Managing Partner who, through Burton Advisory, Inc., provides strategic and financial advice to healthcare companies and investors.
Listed as a judge for the 2Flo Ventures Health Equity Pitch Competition; serves as Executive Director at Roivant Social Ventures.
Listed as a judge for the 2Flo Ventures Health Equity Pitch Competition; serves as Investor at Impact Engine.
An emerging global health leader focused on tackling health disparities and preventable diseases.
Listed as a judge for the 2Flo Ventures Health Equity Pitch Competition; serves as Vice President at OCA Ventures.
Oversees the firm's operations and financial strategy and supports portfolio companies operationally.
Listed as a judge for the 2Flo Ventures Health Equity Pitch Competition; serves as Investment Associate at TAWANI Enterprises.
What they invest in
from 4 of 13 portfolio companiesHealthtech ×2SaaS ×2AI & Machine Learning ×1Biotech ×1Cloud Computing ×1Digital Health ×1Enterprise Software ×1
HQs:United States×3
Investments · 13 tracked
founders shown can be your intro pathDigital health company providing enhanced telehealth solutions for underserved communities.
HealthtechChicago, US
Star Cunningham(Executive Officer)
Focuses on improving access to regenerative stem cell-based therapies for injuries and inflammatory diseases.
Cancer-focused precision health platform enabling early detection and prevention across patient populations.
FDA-approved cannabinoid-based pain relief for hard-to-treat musculoskeletal and neurological conditions.
Airtable is a low-code platform that enables teams to build custom applications on shared data to automate workflows across enterprises.
AI & Machine LearningCloud ComputingEnterprise SoftwareSaaS
Howie Liu(Co-founder and CEO)Andrew Ofstad(Co-founder)Emmett Nicholas(Co-founder)
Virtual care platform built within Epic Systems designed to improve access to safe and integrated medical care.
Life sciences company improving access to antidotes for non-opiate drug overdoses.
Early-stage biotechnology company developing low-cost targeted treatments for metastatic melanoma.
Biotech company developing safe and effective treatment for the skin depigmentation disease vitiligo.
Leverages phospholipid nanoparticles to treat hypovolemia due to septic or hemorrhagic shock.
BiotechChicago, US
Ron Ormand Damper(Director)Harven Ormand DeShield(Executive Officer, Director)Stephen Ormand Keith(Executive Officer, Director)Cuthbert Ormand Simpkins(Executive Officer, Director)Diane Ormand Simpkins(Executive Officer, Director)
Frequently asked questions
- What stage does 2Flo Ventures invest at?
- 2Flo Ventures invests at the Pre-Seed, Seed stages.
- What is 2Flo Ventures's typical check size?
- 2Flo Ventures typically writes checks of $400 – $1K.
- What sectors does 2Flo Ventures focus on?
- 2Flo Ventures focuses on Biotech, Digital Health, Healthtech, Impact & Social Good, Medical Devices, Sector Agnostic.
- Where is 2Flo Ventures located?
- 2Flo Ventures is headquartered in Chicago, US.
- Does 2Flo Ventures lead rounds?
- 2Flo Ventures typically participates in rounds rather than leading them.
Images
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