Digitalis Ventures — Full Portfolio

Judo Bio develops oligonucleotide medicines, including ligand-siRNA conjugate drugs, delivered to the kidney for systemic and renal diseases using its STRIKE (Selectively Targeting RNA Into KidnEy) platform.

BiotechHealthtechCambridge, US

Andrew Fraley(Co-founder)Alfica SehgalOMMER CHOHAN(Executive Officer)JAMES JEFFREY GOATER(Executive Officer, Director)Simon Read(CEO)William Ho

Co-investorsAtlas VentureThe Column GroupDroia VenturesYK Bioventures

Gallant develops regenerative medicine therapies for veterinary care, bringing treatments from laboratory research into clinical practice for pets.

BiotechHealthtechMedical DevicesSan Diego, US

Aaron Hirschhorn(Executive Officer, Director)Linda Black(Chief Executive Officer, Chief Financial Officer & Secretary)Davis Brimer(Executive Officer, Director)

BoardTeymour Boutros-Ghali(Director)inValentine Williams(DVM, MS, Diplomate ACVS)Aaron Schacht(Director)

Board seatMisti Ushio· per SEC Form D · $18M raise · filed Jul 2025

Co-investorsAlpha EdisonBaroda VenturesBling CapitalBold Capital PartnersExpansion Venture CapitalMaveron+1 more

BiotechNew York, US

David Pompliano(Executive Officer)David McElligott(Executive Officer, Promoter)

BoardDavid Schubert(Executive Officer, Promoter)Joel Marcus(Director)Lindsay Rayle(Executive Officer, Promoter)Barbara Dalton(Director)

Board seatMisti Ushio· per SEC Form D · $19.9M raise · filed Jan 2017

Co-investorsPfizer Venture Investments

Sunnyvale, US

BoardJohn Chen(Director)Srinivas Rao(Executive Officer, Director)inNobuyuki Kambe(Director)inBernard Lemaitre(Director)

Board seatMisti Ushio· per SEC Form D · $600K raise · filed Jan 2016

Co-investorsPhoenix Venture Partners

Remote patient monitoring software platform utilizing sensors, predictive analytics, and machine learning for real-time personalized care.

HealthtechNew York, US

Eran Ofir(Executive Officer, Director)Charles Herman(Executive Officer, Director)in

BoardMeir Akkerman(Director)Andrew Gianonne(Director)Christopher Geczy(Director)

Board seatDrew TaylorAmit Bansal· per SEC Form D

Co-investorsEast Post Road Ventures

Alcea Tx develops an immune-tolerance restoration technology that targets Treg cells to reset immune homeostasis in the lungs, with a lead asset aimed at asthma and pulmonary viral infections such as influenza and SARS-CoV2.

BiotechHealthtech

Alpha-9 Oncology develops radiopharmaceuticals for cancer treatment, with a portfolio of molecules in clinical and preclinical development.

BiotechDigital HealthMedical DevicesVancouver, CA

François Bénard(MD)Kuo-Shyan Lin(PhD)David Perrin(PhD)

Co-investorsAndreessen HorowitzDelos CapitalGeneral CatalystLightspeed Venture PartnersLongitude CapitalLumira Ventures+8 more

Alterome is a clinical-stage precision oncology company developing small-molecule, alteration-specific cancer therapies, with two internally discovered drug candidates in the clinic.

AI & Machine LearningBiotechDeep TechSan Diego, US

Eric A. Murphy(Executive Officer, Director, Promoter)Ryan B. Corcoran(Director, Promoter)

BoardThilo Schroeder(Director)inCarl Gordon(Director)inArjun Goyal(Director)in

Co-investorsCanaan PartnersNextech InvestOrbiMedVida VenturesNVIDIA

Ascend is a gene-to-GMP development partner that helps life-science companies advance advanced therapy products from the research bench through clinical stages.

BiotechHealthtechMedical DevicesMunich, DE

Co-investorsCathay HealthMonograph Capital Partners

Aviceda is a company that presents itself as backed by a range of investors, but the page provides no concrete details about its products or business area.

BiotechDigital HealthHealthtechMedical Devices

Mohamed A. Genead(Chairman & CEO)Jeffrey Nau(Chief Executive Officer)Tarek S. Hassan(Chief Development Officer)

Co-investorsJeito CapitalLongitude CapitalOrbiMed

B5 Genomics offers the Benthic Analysis Platform, software that converts microarray and sequencing data (short-read and long-read) into high-resolution genotyping and variant calls for complex genomic regions such as HLA, KIR, and the MHC.

AI & Machine LearningBiotechHealthtech

Bonum Therapeutics develops antibody-controlled protein therapeutics that remain inactive until bound to their target, using a sensor-domain mechanism to deliver regulated, targeted activity.

BiotechHealthtechSeattle, US

John Mulligan(Executive Officer, Director, Promoter)inNeela Patel(Executive Officer)inDiane Hollenbaugh(Executive Officer)in

BoardSamuel Bjork(Director)inMonique Schiersing(Director)inJohn McKearn(Director)in

Co-investorsRiverVest Venture PartnersRoche Venture FundVivo Capital3x5 PartnersCodon Capital

Ansel Health provides health benefit solutions focused on cost-sharing and coverage for unexpected medical bills for employer groups and individuals.

ConsumerHealthtechInsurTechHoboken, US

Veer GidwaneyAmanda Turcotte(Executive Officer)in

BoardColin Beire(Director)Elizabeth Bierbower(Director)

Co-investors500 GlobalCity LightFounder CollectiveBrewer Lane VenturesSixThirty Ventures

Candid develops clear aligner technology and offers remote monitoring services for dental professionals to deliver orthodontic treatment.

ConsumerDigital HealthHealthtechMedical Devices

Nick Greenfield(Co-founder & CEO)in

Co-investorsA-Rod CorpAverin CapitalBessemer Venture PartnersBeyond CapitalF-Prime CapitalKube VC+2 more

Cardurion is a cardiovascular disease-focused company developing therapeutics, with a pipeline advanced through clinical development, trial design, regulatory affairs, and commercialization.

BiotechDigital HealthHealthtechMedical DevicesBurlington, US

Michael E. Mendelsohn(Founder and Chief Strategy Officer)Michael Mendelsohn, M.D.(Founder)in

Co-investorsBain CapitalDelos CapitalNew Enterprise Associates (NEA)

CareDox (operating as SchoolCare) provides a digital health record platform for K-12 school nurse offices that manages immunizations, chronic disease information, and student health compliance reporting.

Digital HealthEdTechHealthtechForest Hills, US

Hesky Kutscher(Executive Officer, Director)

BoardGreg Goff(Director)Eyal Niv(Director)

Co-investorsKima VenturesFirst Round CapitalProlog VenturesTEXO VenturesWestern Technology Investment

Clasp connects employers with healthcare students before graduation and ties student loan repayment to employment, addressing both clinical workforce shortages and student debt.

EdTechFintechHealthtechHR TechBoston, US

Tess Michaels(Founder)in

Co-investorsCrosslink CapitalGSV VenturesJuvo VenturesBlumberg CapitalGradient Ventures

Clasp provides API-based infrastructure and automation for employee health benefits administration, handling quoting, group setup, open enrollment, carrier feeds, and ACA/COBRA compliance.

FintechInsurTechSaaS

Co-investorsTerrainCrosslink Capital

Code Ocean is a cloud computational research platform for reproducible code, data and environments in science.

New York, US

Simon Adar(Executive Officer, Director)

BoardScott Tobin(Director)Joshua Ruch(Director)inMarty Kahn(Director)

Co-investorsBattery VenturesM12 (Microsoft's Venture Fund)Rho Ventures

Eden Brew has developed DeepForte™, a programmable casein micelle platform for nutrient delivery that replicates natural slow-release digestion principles.

BiotechDeep TechFoodTech

Jim Fader(CEO)

Co-investorsBreakthrough VictoriaMain Sequence Ventures

Elegant Bio develops DNA synthesis technology and services, offering ENFINIA™ DNA synthesis at scale for biotech and research applications.

BiotechDeep TechSan Carlos, US

Matthew Hill(Executive Officer, Director)in

BoardPeter Zhou(Director)inCain McClary(Director)inJonathan Sheena(Director)

Co-investorsACVC PartnersAndreessen HorowitzRaptor GroupTriatomic CapitalAME Cloud VenturesIn-Q-Tel+1 more

Elemental Machines provides an IoT platform combining hardware, software, and data science to monitor lab and manufacturing equipment, environments, and workflows in real time.

AI & Machine LearningBiotechHardwareHealthtechIoTSaaSCambridge, US

Sridhar Iyengar(Executive Officer, Director)Una Ryan(Director)Jeff Klemens(Director)Sonny Vu(Director)

BoardGaurav Tewari(Director)inRobert Davoli(Director)in

Co-investorsGutbrain VenturesOmega Venture PartnersTau VenturesFounders FundTenOneTen Ventures

Epibiologics develops protein degradation medicines using protein sciences and antibody engineering capabilities.

BiotechMedical DevicesSan Mateo, US

Ann Lee-Karlon(Executive Officer, Director)Mitchell Mutz(Executive Officer, Director)James Wells(Director)

BoardSamuel Bjork(Director)Alexandra Cantley(Director)Seiji Miyahara(Director)

Co-investorsAvego BioScience CapitalGV (Google Ventures)Mission BiocapitalNovartis Venture FundRoche Venture FundSamsara BioCapital+3 more

Expressable provides online speech therapy delivered by licensed speech therapists for children and adults through live 1-on-1 sessions conducted from home, paired with weekly practice activities and caregiver support.

Digital HealthHealthtechSaaS

Co-investorsNoro-Moseley PartnersSustainVC

Genomics company building a multi-ancestry biobank and AI-driven analytics for clinical genetic testing and drug discovery.

HealthtechMiami Lakes, US

Carlos D. Bustamante(Executive Officer, Director)Arthur Polk(Executive Officer)Alexander Ioannidis(Director)

BoardWale Ayeni(Director)inMohit Kaushal(Director)Nicholas Katsanis(Director)

Co-investorsCEI VenturesCitta CapitalF-Prime CapitalFounder CollectiveFunction VenturesHelios Digital Ventures+2 more

Portfolio company acquired by Roche.

BiotechSeattle, US

John Mulligan(Executive Officer, Director, Promoter)Mitchell Mutz(Director)Nicholas Walrod(Director)

BoardJohn McKearn(Director)inKarl Handelsman(Director)

Co-investorsRiverVest Venture PartnersRoche Venture Fund

GRObio (GRO Biosciences) develops protein therapeutics using non-standard amino acids (NSAAs) via its GRO platform, aiming to improve protein potency, stability, and function.

BiotechDeep TechHealthtechCambridge, US

Daniel J Mandell(Executive Officer, Director)Tracey Lodie(Executive Officer)Christopher Gregg(Director)

BoardMing Fang(Director)Bruce Beutel(Director)Dan Becker(Director)

Co-investorsLeaps by BayerREDMILEDreamers VCRising TideAtlas VentureInnovation Endeavors+1 more

Helm Health provides benefit design and member engagement tools for health plans, incorporating cost and quality data into coverage decisions, bundling claims into transparent pricing, and offering provider search functionality.

Enterprise SoftwareHealthtechInsurTechSan Francisco, US

Co-investors.406 Ventures3CC | Third Culture CapitalFlare Capital PartnersHeadwater VenturesSemperVirens Venture CapitalInitialized Capital

Kingdom Supercultures develops functional health ingredients using natural microbes, aiming to improve consumer health.

BiotechFoodTechHealthtechNew MaterialsWellness & Fitness

Co-investors4DX VenturesFour Acres CapitalShine CapitalLux CapitalSALTSupernode Ventures+1 more

Varda industrializes low Earth orbit by manufacturing pharmaceuticals and other specialized products in space, then returning them to Earth via reusable reentry capsules.

BiotechDeep TechSpace TechEl Segundo, US

Will Bruey(Co-founder)inDelian Asparouhov(Co-founder)in

Co-investorsAlso CapitalCaffeinated CapitalFounders FundKhosla VenturesLux CapitalGeneral Catalyst+25 more

Discovering precision small molecule medicines that harness the power of covalency to transform the treatment of immune diseases.

Cambridge, US

Co-investorsAccess BiotechnologySanofi Ventures

Matchpoint Therapeutics is a drug discovery company developing precision small molecule covalent medicines to treat immune and inflammatory diseases.

AI & Machine LearningBiotechDeep Tech

Andre TurenneJared Cumming(PhD)Christopher HrenThomas Durand-Reville(PhD)Wei Li(MD)Paola Castaldi(PhD)

Co-investorsAtlas VentureSanofi Ventures

Functional nutrition company making supplements for dogs.

St Louis, US

Patrick M Barron(Manager / Member)

Co-investorsCompanion FundR/GA VenturesSelva VenturesCAVU Consumer PartnersCAVU Venture Partners

Neion Bio uses genetic engineering to turn chicken eggs into production systems for recombinant biologic proteins.

Co-investorsCaffeinated CapitalHAWKTAILBasis Set VenturesEnsemble VCHaystackTrust Ventures

Nuvig Therapeutics develops immune-modulating medicines for autoimmune diseases by harnessing endogenous regulatory mechanisms to resolve immune dysregulation.

BiotechHealthtechMedical Devices

Pamela Conley(Founder)in

Co-investorsB Capital GroupB4 CapitalGlobal BioAccess FundMission BiocapitalSanofi VenturesNorwest Venture Partners

Nomina is a unified trading terminal for perpetual future decentralized exchanges (perp DEXs) that lets DeFi users run and automate advanced cross-exchange trading strategies.

Crypto & Web3Data & InfrastructureFintech

Tyler Tarsi(Co-Founder and CTO)Austin King(Founder)in

Co-investorsPantera CapitalCraft VenturesICONIQIW CapitalLever VCRedrice Ventures

Onc.AI develops the Onclara platform, which uses oncology real-world data to build predictive and prognostic AI models for cancer decision-making.

AI & Machine LearningBiotechDigital Health

Co-investorsLifeX VenturesKdT Ventures

Novel antibody-based therapeutics platform for animal health.

Co-investorsCambridge Innovation CapitalCompanion FundParkwalk Advisors

Positive Development provides autism therapy and developmental care services for neurodivergent children and their families.

Digital HealthHealthtechMedical DevicesMental HealthMclean, US

Mike Suiters(Executive Officer, Director)Nick Whitehead(Director)in

BoardAdam Seabrook(Director)inDaniel Gebremedhin(Director)John Banta(Director)Brenton Fargnoli(Director)in

Co-investorsAlleyCorpB Capital GroupB4 CapitalFlare Capital PartnersLifeforce CapitalObvious Ventures+2 more

Protego Bio is a biotech company developing first-in-class therapies for protein misfolding diseases, including its lead candidate PROT-001 for AL amyloidosis, based on research into pharmacological chaperones.

AI & Machine LearningBiotechDeep TechDigital HealthSan Diego, US

Co-investorsDroia VenturesNovartis Venture FundForbionLightspeed Venture PartnersMPM BioImpactVida Ventures+1 more

BiotechHealthtechSan Diego, US

Brent J. Warner(Executive Officer, Director)XIN JIANG(President & CEO)HANK MICHAEL PETRASSI(Executive Officer)JEFFERY KELLY(Director)

BoardTIM LOHOFF(Director)EDWARD HURWITZ(Director)

Co-investorsDroia VenturesForbionLightspeed Venture PartnersMPM BioImpactNovartis Venture FundVida Ventures+1 more

Reema Health develops technology solutions for health plans to engage and serve Medicaid, Commercial, and Medicare members facing barriers to care, particularly those hardest-to-reach populations with complex clinical and social needs.

Digital HealthHealthtechMental HealthMinneapolis, US

Justin Ley(CEO)Matt(Chief Product Officer)

BoardHelen Ciesielski(Director)Matthew Swanson(Director)Ellen Herlacher(Director)Amon Anderson(Director)

Co-investorsGROOVE CAPITALHC9 VenturesHeadwater VenturesLRVHealthMaC Venture CapitalMatchstick Ventures+2 more

Rejuvenate Bio develops gene therapy treatments aimed at the root causes of aging to address chronic, age-related conditions such as osteoarthritis, heart disease, and cancer.

BiotechHealthtechLongevitySan Diego, US

Noah Davidsohn(CSO, Co-Founder)Daniel Oliver(CEO, Co-Founder)George Church(Co-Founder and SAB)Deborah Ascheim(Chief Medical Officer)

BoardDavid Zhu(Director)in

Co-investorsCompanion FundConnecticut InnovationsKendall Capital PartnersKdT Ventures

Scout Bio developed biotechnology therapies for pets, including a pipeline of monoclonal antibodies and gene therapy programs targeting chronic diseases in companion animals.

AgTechBiotechDeep TechHealthtechPhiladelphia, US

Mark Hefferman(Executive Officer, Director)

BoardAditya Kohli(Director)inTadataka Yamada(Director)Patrick Heron(Director)inCindy Cole(Director)inNancy Hong(Director)

Co-investorsCompanion FundFrazier Life SciencesRiverVest Venture Partners

Scratch Pay offers point-of-payment patient financing that lets clients of veterinary practices apply for loans and receive instant decisions, with practices paid up front via ACH.

ConsumerFintechHealthtechLos Angeles, US

John(Founder/CEO)Caleb(Founder/President)John Keatley(Founder)

Co-investorsArgonautic VenturesCompanion FundNorwest Venture PartnersStruck CapitalSWS Venture CapitalTTV Capital

Co-investorsLifeforce CapitalPfizer Venture Investments

BiotechWaltham, US

Ellen E. Sheets(Executive Officer, Director)

BoardCarl M. Berke(Director)Nancy Hong(Director)

Co-investorsBold Capital PartnersRiverVest Venture PartnersKdT Ventures

Switch Therapeutics develops RNA interference (RNAi) therapeutic applications targeting central nervous system diseases, leveraging research from Caltech, Harvard Medical School, and City of Hope.

AI & Machine LearningBiotechDeep TechMedical DevicesSouth San Francisco, US

Si-Ping Han(Secretary)Deepshikha Datta(Chief Executive Officer and President)

BoardKevin Zhang(Director)Alicia Irurzun-Lafitte(Director)inDylan Morris(Director)

Co-investorsBold Capital PartnersCRV (Charles River Ventures)FREEFLOWGlobal BrainOno Venture Investment, Inc.Upfront Ventures+2 more

T-Therapeutics develops T cell receptor-based therapeutics for cancer and autoimmune diseases using its proprietary OpTiMus platform, which identifies antigen-specific human TCRs.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesCambridge, GB

Co-investorsF-Prime CapitalSanofi VenturesSofinnova PartnersCambridge Innovation Capital

Terray is a drug discovery company that combines proprietary hardware, large-scale experimental datasets, and AI through its EMMI platform to design small molecule medicines.

AI & Machine LearningBiotechDeep Tech

Eli Berlin(Founder)in

BoardChris PicardoinDusan PerovicSid ShenaiinSamuel BjorkinBassil Dahiyat, Ph.D.

Co-investorsDeviation CapitalMadrona Venture GroupSummit Peak InvestmentsKdT VenturesMana VenturesNVentures+1 more

Transcera is a biotech company developing a new class of therapeutics that use natural lipid trafficking pathways to direct extracellular proteins into lysosomes for degradation, targeting soluble and membrane proteins to treat chronic diseases.

BiotechDeep TechBoston, US

Co-investorsTau Ventures