Matthew De Silva
InvestorFounderVenture Partner at Builders VC
Chicago, Illinois
Writes $100K – $5M checks · typically $1.5M
FoundedNotable Labs · YC
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Experience
- Builders VCVenture Partnercurrent2021 — presentSan Francisco Bay Area
- Longtail Health VenturesAngel Investor & Syndicate Leadcurrent2021 — presentChicago, Illinois, United States
- PathosChief Operating Officer2021 — 2026Chicago, Illinois, United States
- Notable LabsFounder & Executive Chairman2020 — 2023San Francisco Bay Area
- Notable LabsFounder and CEO2014 — 2020San Francisco Bay Area
- Clarium Capital ManagementPortfolio Manager2012 — 2014San Francisco Bay Area
- Bank of America Merrill LynchAnalyst2011 — 2012Chicago, Illinois, United States
- Moore Capital ManagementIntern2010New York City Metropolitan Area
Skills & more
+1 more
LeadershipLanguages English
From Matthew's professional profile.
Deals · 1
Notable LabsBoard seat
via Builders VC · filed Jul 2022 · $10.5M raise
Attribution from SEC filings, press coverage, and firm rosters.
Other disclosed investments
Investor
Arpeggio BioEigen TherapeuticsEnveda BiosciencesStrand AI
Sources: SEC Form D filings · curated public sources.
Colleagues at Builders VC
Network2
Investors connected to Matthew in public investor directories — a warm-intro map.
Frequently asked questions
- Who is Matthew De Silva?
- Venture Partner, Health at Builders VC
- Where does Matthew De Silva work?
- Matthew De Silva is Founder/CEO of Notable Labs and Venture Partner at Builders VC.
- What check size does Matthew De Silva write?
- Matthew De Silva typically writes checks of $100K – $5M.
- What companies did Matthew De Silva found?
- Matthew De Silva founded Notable Labs.
- What boards does Matthew De Silva sit on?
- Matthew De Silva holds tracked board seats at Notable Labs.
- What companies has Matthew De Silva invested in?
- Investments tracked here include Arpeggio Bio, Eigen Therapeutics, Enveda Biosciences, Strand AI.
- Where did Matthew De Silva go to school?
- Matthew De Silva studied at Cornell University (B.S., Applied Economics & Management); Purdue University Daniels School of Business (Operations Management).
Founder mafias
Y Combinator mafia10,595
Also came through, then founded or led a company.
Cornell mafia665
Also came through, then founded or led a company.
Purdue University Daniels School of Business mafia20
Also came through, then founded or led a company.
Builders VC mafia5
Also came through, then founded or led a company.
Pathos mafia4
Also came through, then founded or led a company.
Same school
Also attended Cornell University1,445
+ 1,439 more
Also attended Purdue University Daniels School of Business55
+ 49 more
Shared employers
Also worked at Builders VC22
+ 16 more
Also worked at Notable Labs5
Also worked at Clarium Capital Management21
+ 15 more
Also worked at Bank of America Merrill Lynch408
+ 402 more































































