Polychain Capital — Full Portfolio

Eclipse is a Layer 2 blockchain network for Ethereum that runs the Solana Virtual Machine (SVM), combining Solana's execution speed with Ethereum's liquidity to support high-throughput decentralized applications.

Crypto & Web3Developer ToolsFintech

Neel Somani(Founder)Vijay Chetty(CEO)Terry Chung(Head of Strategy)Ben Livshits(CTO)

Co-investorsHack VCDBAFenbushi CapitalMaven 11OKX VenturesPlaceholder+5 more

Eclipse builds an Ethereum Layer 2 network that uses the Solana Virtual Machine (SVM) as its execution environment, combining Solana's high-throughput execution with Ethereum's liquidity and security.

Crypto & Web3Data & InfrastructureDeveloper Tools

Neel Somani(Founder)Vijay Chetty(CEO)Ben Livshits(CTO)

Co-investorsDBAFenbushi CapitalHack VCMaven 11OKX VenturesPlaceholder+5 more

Fluent Labs develops blockchain infrastructure and consumer products, including the Fluent Network with blended execution that allows programs written for different virtual machines to run within the same blockchain state.

Crypto & Web3Data & InfrastructureDeveloper Tools

Co-investorsSymbolic Capital

Glow finances and deploys solar energy installations across multiple continents to reduce carbon emissions at scale.

CleantechClimate TechEnergy

David Vorick(Founder & CEO)

Co-investorsAndreessen HorowitzLattice CapitalTranspose Platform Management

MonkeyTilt is a crypto-based online gambling platform offering casino games (slots, live dealer tables, game shows, and exclusive originals), a sportsbook with pre-match and live betting, and poker, all funded through cryptocurrencies.

ConsumerCrypto & Web3GamingSan Jose, CR

Sam Kiki(Founder)

Co-investorsPantera CapitalCoinFundHack VCPaper Ventures

AltLayer provides infrastructure and autonomous agents for building intelligent applications on decentralized blockchain networks, including services for AI model access, DeFi integration, and rollup deployment.

AI & Machine LearningCrypto & Web3Developer Tools

BoardBalaji Srinivasan

Co-investorsBankless VenturesBollinger Investment GroupBreyer CapitalHack VCIOSG VenturesMoonhill Capital+3 more

Anoma is a blockchain protocol redesigned from first principles as digital infrastructure for self-sovereign coordination, aiming to give users control over the systems they use and provide a substrate for decentralized global coordination.

Crypto & Web3Data & InfrastructureDeep TechEnterprise Software

Adrian Brink(Co-founder)Christopher Goes(Co-founder)Awa Sun Yin(Co-founder)

Co-investorsBixin CapitalBixin VenturesCVP NoLimitElectric CapitalFigmentFlowdesk+11 more

Axelar is a blockchain interoperability network that connects institutions to onchain ecosystems through a single integration, letting them deploy stablecoins, real-world assets, and funds across 80+ blockchains.

Crypto & Web3Data & InfrastructureFintechWaterloo

Sergey Gorbunov(Executive Officer, Director)Georgios Vlachos(Director)

Co-investorsAndromeda CapitalBitDAOCoinbase VenturesCollab+CurrencyDCVC (Data Collective)Divergence+11 more

Bitlayer is a Bitcoin-focused blockchain infrastructure project offering YBTC (yield-bearing BTC), multichain support, and BTC deposit and trading functionality.

Crypto & Web3Data & InfrastructureFintech

Charlie Hu(Founder)Kevin He(Founder)in

Co-investors57Blocks CapitalABCDE CapitalAlphaLab CapitalBaseTwoCaladanNxGen+10 more

Blueprint provides an AI assistant and AI-native EHR for therapists and mental health practices, automating session transcription, clinical documentation, treatment plans, and administrative tasks like scheduling, billing, and telehealth.

AI & Machine LearningDigital HealthMental Health

Danny Freed(Founder)in

Co-investorsBonfire VenturesData TechLeverageVCA16Z SpeedrunBitGoFlowdesk+2 more

Blueprint offers an AI assistant for therapists and mental health practices that transcribes sessions, drafts clinical notes and treatment plans, and provides client summaries and guided interventions.

AI & Machine LearningDigital HealthMental Health

Danny Freed(Founder)in

Co-investorsBeringeaOperator CollectiveTau VenturesAndreessen HorowitzBitGoEnsemble VC+2 more

Botanix is a Bitcoin-based blockchain platform for applications focused on Bitcoin financialization.

Crypto & Web3New York, US

Willem Schroe(Executive Officer)

Co-investorsEdessa CapitalMetamatic GroupPlaceholder VCWeb3com Ventures

Houston, US

JASON CALEY-BRANNIGAN(Executive Officer)BRIAN BERMAN(Executive Officer)SAMUEL GREEN(Executive Officer, Director)

Co-investorsBlockchain BuildersFlow TradersFranklin TempletonNomad CapitalPaper VenturesSelini Capital

Canza Finance is a Web3 company combining DeFi, crypto-assets, and traditional financial infrastructure to provide financial products for individuals and businesses in Africa and other emerging markets.

Crypto & Web3Fintech

Pascal Ntsama IV(Co-founder & CEO)Oyedeji Oluwoye(Co-founder & CMO)

Co-investorsAdaverseFenbushi CapitalFlori VenturesHyperithmMapleblock CapitalStratified Capital+3 more

San Francisco open-source software developer building DeFi tools and the Compound Protocol for crypto lending and borrowing.

San Francisco, US

Robert Leshner(Executive Officer, Director)Geoffrey Hayes(Director)

Co-investorsDragonflyMetastableAndreessen HorowitzBain Capital VenturesDanhua CapitalParadigm+1 more

Connext provides xCall, a developer tool that enables applications to interact with users, tokens, and other applications across multiple blockchains.

Crypto & Web3Developer ToolsSan Francisco, US

Arjun Bhuptani(Executive Officer, Director)Layne Haber(Executive Officer, Director)inRahul Sethuram(Executive Officer)

Co-investorsA.Capital VenturesAmentum Investment ManagementCVP NoLimitD1 VenturesFenbushi CapitalFigment+13 more

Cubist develops cryptographic proof systems and tools for verifying software correctness and security, serving developers and organizations building secure systems.

Crypto & Web3CybersecurityDeveloper ToolsEnterprise Software

Riad(CEO)inAnn(COO)inFraserinDeianinRohanin

Co-investorsAmplify PartnersPROOFSymbolic CapitalVery Serious VenturesZero Knowledge Validator (ZKV)Amplify Partners CV+2 more

DAWN is a decentralized broadband network that enables users to share internet capacity and operate as their own internet providers through a hardware node and protocol system.

Crypto & Web3

Co-investors6th Man VenturesAdvancit CapitalArchetypeEv3 Ventures LlcFlowdeskLattice Capital+3 more

DFINITY builds the Internet Computer, a decentralized cloud network that enables applications to run directly on the blockchain with persistent state, native HTTP serving, and built-in security without requiring external databases or a dedicated operations team.

AI & Machine LearningCloud ComputingCrypto & Web3Developer Tools

Dominic Williams(Founder)

Co-investorsa16z cryptoAcrew CapitalAmino CapitalAndreessen HorowitzAspect VenturesBollinger Investment Group+15 more

Open source DeFi protocol enabling users to seek high fixed yield income on the blockchain.

North Richland Hills, US

Jonathan Rhea(Chief Financial Officer and Secretary)William Shatswell Villanueva(President and Chief Executive Officer)

Co-investorsAdvanced Blockchain

Espresso Systems builds Ethereum infrastructure and blockchain systems with a focus on practical solutions for developers and users within the crypto ecosystem.

Cloud ComputingCrypto & Web3Data & InfrastructureDeveloper ToolsNew York, US

Ben Fisch(Chief Executive Officer)inCharles Lu(Chief Operating Officer)Benedikt Bünz(Chief Scientist)Jill Gunter(Chief Strategy Officer)Fernando Krell(VP Engineering)Ellie Davidson(Chief Product Officer)

Co-investorsa16z cryptoAlameda ResearchAndreessen HorowitzBlockchain CapitalCoinbase VenturesElectric Capital+8 more

Ethena operates a crypto protocol offering USDe, a digital dollar, and sUSDe, a reward-accruing asset backed by collateralized assets with third-party attestations.

Crypto & Web3Fintech

Guy Young(Founder & CEO)in

Co-investorsAlphaLab CapitalBitDAOBreedCaladanCVP NoLimitF-Prime Capital+17 more

Boston, US

Zachary Herbert(Executive Officer, Director)Kenneth Carpenter(Director)

BoardOleg Mikhalskiy(Director)

Co-investorsLightning VenturesThird PrimeUnpopular Ventures

Handshake is a decentralized, peer-to-peer naming and certificate authority protocol that serves as an alternative to centralized DNS systems and certificate authorities.

Crypto & Web3Data & InfrastructureDeveloper Tools

Joseph Poon(Co-Founder / Protocol Developer)Andrew Lee(Co-Founder)Christopher Jeffrey(Co-Founder / CTO)Tieshun Roquerre(CEO, Namebase (leading Handshake domain registrar/exchange))

BoardMike Duboe(Venture Partner, Greylock Partners (investor listed on Greylock's Handshake portfolio page))

Co-investorsa16z cryptoAmentum Investment ManagementAusum VenturesD1 VenturesDraper AssociatesFounders Fund+5 more

Hyperbolic provides on-demand, reserved, and private cloud access to high-performance GPUs (such as H100, H200, and B200) through a global network of compute providers.

AI & Machine LearningCloud ComputingData & Infrastructure

Co-investorsAmbush CapitalBig Brain HoldingsFactionGSRLongHash VenturesSamsung Next+4 more

The Internet Computer is a serverless "sovereign cloud" run by independent hardware operators, hosting tamperproof WebAssembly/Motoko software and multi-blockchain digital-asset APIs.

AI & Machine LearningCloud ComputingCrypto & Web3

Co-investorsDraft Ventures LlcAndreessen Horowitz

AI-powered sales training and coaching software that enables personalized learning, skills reinforcement, and seller effectiveness through interactive training, data-driven insights, and coaching playbooks.

AI & Machine LearningEnterprise SoftwareSaaSSales TechIndianapolis, US

John Maxwell Yoder(Executive Officer, Director)Conner Burt(Founder)inMichael Fitzgerald(Executive Officer, Director)in

BoardEric Tobias(Director)inKristian Andersen(Director)in

Co-investorsAllos VenturesElevate VenturesHigh AlphaJackson Square VenturesJMI EquityOpenView Venture Partners+6 more

Liquity is a decentralized finance protocol that enables borrowing against crypto collateral with minimal requirements.

Crypto & Web3Fintech

Robert Lauko(Founder)Rick Pardoe(Co-Founder & Lead Engineer)

Co-investors1k(x)1kxA.Capital VenturesIOSG VenturesLemniscapPantera Capital+3 more

M0 provides a modular platform for designing and deploying stablecoins, with configurable layers for token behavior, issuance, and partner integrations.

Crypto & Web3Fintech

Gregory Di Prisco(Founder)in

Co-investorsEarlybird Venture CapitalKraynos CapitalMouro CapitalPantera CapitalParaFi CapitalBain Capital Crypto+4 more

M0 is a modular stablecoin infrastructure platform that lets developers launch application-specific, interoperable digital dollars.

Luca Prosperi(Founder & CEO)Greg Di Prisco(Founder)

Co-investorsA-Rod CorpArrington CapitalBain Capital CryptoBitcoin MagazineCitizenX Crypto VenturesCoinbase Ventures+20 more

Manta Network is a modular Layer 2 blockchain platform offering low gas fees and high performance for building decentralized applications.

Crypto & Web3Data & InfrastructureDeveloper Tools

Co-investorsAdvanced BlockchainAlliance DAO (ex DeFi Alliance)AZDAGGenblock CapitalHypersphere VenturesLongHash Ventures+5 more

Maple is an onchain asset management platform offering institutional-grade lending and yield strategies to the crypto ecosystem.

Crypto & Web3Fintech

Joe Flanagan(Founder)in

Co-investorsArctic DigitalBlack DragonBloccelerate VCGSRMarin Digital VenturesMaven 11+4 more

Security and encryption platform for distributed systems.

San Francisco, US

MacLane Wilkison(Founder)

Co-investors1k(x)1kxAmino CapitalBase Venture Management, Inc.Ceras VenturesContinue Capital+2 more

Polychain is an investment firm that manages actively managed portfolios of blockchain-based digital assets, focusing on returns from the cryptocurrency sector.

Crypto & Web3

Olaf Carlson-Wee(Founder & CEO)in

Co-investorsA.Capital VenturesAbstract VenturesAndreessen HorowitzBollinger Investment GroupMirana VenturesMoonhill Capital+7 more

Polyhedra Network builds blockchain infrastructure for AI applications, including EXPchain, a chain for verifiability, data security, and performance of AI systems, and the ZKJ token for gas and governance.

AI & Machine LearningCrypto & Web3Data & Infrastructure

Tiancheng X.(Founder)in

Co-investorsArcane GroupL2 Iterative Ventures (L2IV)LongHash VenturesMapleblock CapitalPuzzle VenturesRR2 Capital+7 more

Quasar provides a distributed database that keeps live data ingestion, deep historical storage, and heavy analytics on the same dataset, making new data queryable as it arrives without warehouse loading cycles.

Data & InfrastructureDeep TechEnterprise Software

Co-investorsNewfund CapitalTech Square VenturesBlockchain CapitalGalileoHash CapitalHash CIB+2 more

Gaming studio building a AAA first-person extraction shooter

Ken Rosman(CEO)

Co-investorsBixin CapitalBixin VenturesCVP NoLimitDragonflyMetastableNo Limit Holdings (NLH)+7 more

Silhouette offers shielded onchain trading on the Hyperliquid network, using encryption to protect traders' order flow and strategies from exploitation while accessing HyperCore's orderbook liquidity.

Crypto & Web3Fintech

Chandler(Co-founder)Stenton(Co-founder)Aidan(Head of Engineering)

Co-investorsHivemind Capital PartnersProtagonistRockawayX6th Man VenturesAmber GroupHivemind Capital LLC

Solayer is a hardware-accelerated blockchain and financial platform that enables trading of crypto, equities, and commodities on a high-performance L1 blockchain, along with a crypto-native payment card for global spending.

Crypto & Web3Fintech

Co-investorsFOMO VenturesHack VCProtagonistBig Brain Holdings

StakeStone is a crypto-native neo bank offering self-custody accounts with yield-bearing balances, gasless transactions, and borderless payments across DeFi and CeFi venues.

AI & Machine LearningCrypto & Web3Fintech

Cheryl Liu(Founder)in

Co-investorsSymbolic CapitalBinance LabsOKX VenturesSevenX Ventures

Structure is a no-code platform for building, backtesting, and deploying automated crypto trading strategies on Web3, letting users describe a strategy in plain English and run it as a deterministic on-chain strategy.

AI & Machine LearningCrypto & Web3Fintech

Co-investorsContinue CapitalKane & Rao Group

Superform offers an onchain neobank application and SuperformOS, an operating system for crypto vaults.

Crypto & Web3FintechMiami, US

Alex Cort(Founder)

Co-investorsHypersphere VenturesMaven 11Node Capital

Vespene Energy is an energy development company that provides fully managed, end-to-end electricity solutions, including biogas-to-power projects that convert waste streams into electricity and behind-the-meter on-site generation.

CleantechClimate TechEnergy

Co-investorsNew Layer CapitalSTILLMARKVibe Capital