Oxford Science Enterprises — Full Portfolio

PepGen is a clinical-stage biotech company developing oligonucleotide therapies for neuromuscular and neurological diseases using its Enhanced Delivery Oligonucleotide (EDO) platform to improve tissue penetration and uptake in muscle tissues.

AI & Machine LearningBiotechHealthtechMedical DevicesBoston, US

JMJames McArthur(Executive Officer, Director)inNPNoel P. Donnelly(Chief Financial Officer)inJDJoseph D. Vittiglio(Chief Business & Legal Officer and Secretary)inKKKasra Kasraian(Chief Technical Officer)in

BoardRFRamin Farzaneh-Far(Director)inJoshua Resnick(Director)

Co-investorsRARA CapitalVIViking Global

Beacon Therapeutics develops gene therapies for patients with serious diseases that lack or have limited treatment options, including investigational products like laru-zova for genetic conditions.

BiotechDigital HealthMedical Devices

DCDaniel Chung(Chief Medical Officer)inLBLance Baldo(Chief Executive Officer)inASAbraham Scaria(Chief Scientific Officer)in

Co-investorsADAdvent Life SciencesFOForbionTCTCG Crossover

Sereact builds AI foundation models that enable industrial robots to perform complex manipulation tasks like warehouse picking and returns handling without retraining.

Advanced ManufacturingAI & Machine LearningDeep TechEnterprise SoftwareQuantum ComputingRoboticsOxford, GB

Ralf Gulde(CEO and co-founder)Marc Tuscher(CTO and co-founder)Gerald Mullally(CEO)

Co-investorsALAlpha EdisonBRBritish Business BankCHChevron Technology VenturesINInvusBABackstage AB

Dark Blue Therapeutics develops novel medicines for cancer through integrated drug discovery combining internal expertise with academic partnerships.

BiotechDeep TechHealthtechLondon, GB

AMAlastair MacKinnon(Chief Executive Officer)in

ModelLabs develops open microcavity sensing technologies for remote environmental monitoring.

AI & Machine LearningCleantechClimate TechDeep TechHardwareQuantum ComputingOxford, GB

Daniel Miles-Barrett(CTO)Prof. Jason Smith(Academic Founder)Dean James(CEO)in

OMass is a biotech company that originated as a spinout from Oxford University, developing specialized treatments for patient populations with high unmet medical needs.

BiotechDeep TechDigital HealthHealthtechMedical DevicesOxford, GB

PDProfessor Dame Carol Robinson(Founder and Chair of Scientific Advisory Board)ILIdlir Liko(Founder)inJHJonathan Hopper(Vice President, Platforms and Founder)inHYHsin Yung (Jason) Yen(Founder)inRDRos Deeganin

Co-investorsGVGV (Google Ventures)SASanofi VenturesNONorthpond Ventures

Opsydia develops optical and photonic technologies for precision manufacturing, emerging from research in adaptive optics and laser processing at the University of Oxford.

Advanced ManufacturingAI & Machine LearningDeep TechHardwareNew MaterialsSemiconductorsOxford, GB

MBMartin Booth(Founder and Director)inPSPatrick Salter(Founder and Director)inDr. Noel Moore(Chief Technology Officer)

BoardNigel Vaughan(Chairman)

Co-investorsFOForesight GroupOXOxford University InnovationPAParkwalk Advisors

Oxford Quantum Circuits (OQC) develops and operates superconducting quantum computers for commercial and strategic applications, offering Quantum-Compute-as-a-Service and integrating quantum systems directly into commercial data centres.

Deep TechEnterprise SoftwareHardwareQuantum ComputingOxford, GB

PLPeter Leek(Founder & CSO)inGerald Mullally(CEO)inSPSimon Phillips(CTO)inNCNikki Cooper(CLO)inRCRobert Coutts(CFO)in

BoardJBJack Boyer(Chairman of the Board)

Co-investorsBRBritish Business BankOXOxfordOXOxford Investment Consultants LLPUTUTEC

Refeyn develops mass photometry instruments that measure the mass of individual biomolecules in solution without labels, enabling analysis of protein purity, interactions, and viral vector characterization for research and manufacturing applications.

BiotechDeep TechHardwareMedical DevicesOxford, GB

PKPhilipp Kukura(Founder)DCDan Cole(Chief Scientist and co-founder)inJBJustin Benesch(Co-founder)in

Co-investorsFOForesight GroupHOHorizons VenturesOXOxford Technology Management

Seloxium develops a metal recovery and refining technology (branded "Selectal") used for tailings reprocessing, wastewater treatment, bulk metal recovery, and high-purity refining.

Circular EconomyCleantechDeep TechNew MaterialsTeesside, GB

CPChristian Peters(CEO & Co-founder)inSteve Colley(Co-founder, Technical Advisor & Director)NHNick Hankins(Co-founder, Scientific Advisor & Director)Steve van Zutphen(Co-founder, CEO Advisor)DRDr Richard Dixon(CCO)Roberto Ricci(CFO)in

Co-investorsOXOxford Investment Opportunity Network (OION)EMEmpirical Ventures

Singular Machines develops AI-native engineering tools for designing complex machines, facilities, and infrastructure in the advanced manufacturing sector.

Advanced ManufacturingAI & Machine LearningDeep Tech

Co-investorsUKUK Innovation & Science Seed FundMIMIRAI SOUZOU

Sitryx is a biotechnology company, founded in 2018, developing therapeutics with a focus on immunometabolism.

BiotechDeep TechHealthtech

Co-investorsLOLongwood FundSOSofinnova PartnersSVSV Health InvestorsDEDementia Discovery Fund

Snow Fox Discovery explores for and develops natural (geologic) hydrogen resources, aiming to supply low-carbon hydrogen for a net-zero energy transition.

CleantechClimate TechEnergy

DMDaniel McMahonin

Co-investorsAPAP VenturesOXOxfordBPbp ventures

Theolytics develops systemically deliverable immunotherapies based on oncolytic adenoviruses designed to target solid tumours and their supporting microenvironment.

BiotechHealthtech

Co-investorsEPEpidarex CapitalSOSound BioventuresTATaiho Ventures, LLCM M Ventures

Ultromics develops AI models that analyze routine echocardiography studies to help clinicians detect HFpEF and screen for cardiac amyloidosis, delivered through a single workflow platform.

AI & Machine LearningDigital HealthMedical Devices

RURoss Upton(Founder & CEO)in

Co-investorsGVGV (Google Ventures)LELegal & GeneralFUFuture Planet CapitalNINina CapitalNONovaCapitalOPOptum Ventures+4 more

AI-powered platform for online fashion designed to simplify the shopping experience.

AI & Machine LearningE-commerceMarketing TechRetail TechSaaSAbingdon, GB

Duncan McKay(Founder & CEO)inPTPhil Torr(Founder & Chief Technologist)in

Co-investorsLOLoyal VCTETechstars

Allos offers an AI platform that simulates how process interventions affect outcomes to define robust operating windows before physical experiments are run, supporting pharmaceutical development from formulation through scale-up, tech transfer, QA, and clinical trials.

AI & Machine LearningBiotechHealthtech

Co-investorsOXOxford University Innovation

AlveoGene develops respiratory gene therapies, led by executives and academic researchers from the UK Respiratory Gene Therapy Consortium.

BiotechDeep TechDigital HealthHealthtechMedical Devices

DHDavid Hipkiss(Executive Chair)in

Co-investorsOLOld College Capital

Amber Therapeutics develops medical technology focused on treating mixed urinary incontinence, advancing toward pivotal clinical trials in the US with expanded feasibility studies in Europe.

Medical Devices

Co-investorsF-F-Prime CapitalINIntuitive VenturesLILightstone VenturesNENew Enterprise Associates (NEA)

Archangel builds laser (optical) communication systems that connect satellite networks in space with terrestrial networks, offering an alternative to radio frequency and subsea cable infrastructure.

Deep TechHardwareSpace Tech

Co-investorsBLBlackfinch VenturesOXOxford

Ascension develops technology related to the extraction or supply of critical materials used in applications such as magnets for wind turbines, solar panel coatings, speakers, displays, and batteries.

CleantechDeep TechNew Materials

Jonathan Blundy(Co-founder)Mike Kendall(Co-founder)Motoaki Sumi(Co-founder)in

Co-investorsFUFuture Planet CapitalUKUK Innovation & Science Seed Fund

BehaVR develops VR-based (XR) therapeutics for mental and behavioral health, translating clinical science into immersive programs that address stress, anxiety, fear, pain management, addiction recovery, and maternal health.

Digital HealthHealthtechMental HealthElizabethtown, US

Aaron Gani(Executive Officer, Director)

Co-investorsCHChrysalis VenturesKEKeyhorse CapitalPOPoplar VenturesACAccenture VenturesFRFrist Cressey VenturesFUFuture Labs Capital+1 more

BibliU is a digital learning platform that partners with publishers to provide students affordable, instant access to course content, and offers institutions workflow automation to reduce administrative burden.

EdTechSaaS

DSDave Sherwood(CEO & Co-Founder)in

Co-investorsBRBrick Capital VenturesGRGreen Shores CapitalGUGuinness VenturesKRKreos CapitalPAParkwalk AdvisorsBEBeyond Ventures+4 more

University of Oxford spinout whose imaging technology aids diagnosis and treatment of cardiovascular disease.

Co-investorsBUBusiness Growth FundCRCreative Destruction Lab (CDL)LOLongwall Venture Partners LLPOXOxford Investment Consultants LLP

Covatic develops an on-device advertising platform powered by AI and machine learning that identifies user cohorts and delivers targeted ads while preserving consumer privacy.

AdTechAI & Machine LearningIoTLondon, GB

NPNick Pinks(Founder)in

Co-investorsCRCreative UKOXOxford Technology ManagementTETechstarsTETechstars Ventures 2022

Densix develops high power-density power converters aimed at applications including data centres, power grids, EV charging, and renewable energy.

CleantechEnergyHardware

Co-investorsOXOxford University Innovation

Diffblue offers an AI-powered solution that automatically generates Java unit tests, freeing developers from manual test writing.

AI & Machine LearningDeveloper ToolsEnterprise Software

Co-investorsALAlbionVCPEPerivoli InnovationsIPIP Group

Endlyz develops small-molecule disease-modifying therapeutics targeting the ATP13A2 and ATP10B lysosomal transporters to restore endo-lysosomal function and counter neurodegeneration.

BiotechDeep TechBoston, US

JWJoanna Wolak(Executive Officer, Director)inJonathan Behr(Director)John Gustofson(Director)Damian Crowther(Director)Zaven Kaprielian(Executive Officer, Director)

BoardLBLaurence Barker(Director)

Co-investorsDEDementia Discovery Fund

Evolito develops and manufactures electric propulsion and power generation systems for aerospace, including electric engines, motors, and motor control systems for type-certifiable and volume-manufactured applications.

CleantechHardwareMobility & Transportation

Co-investorsPEPerivoli Innovations

Evox Therapeutics develops exosome-based gene editing therapies using its ExoEdit platform, which combines exosome delivery with a proprietary CRISPR-based editor to treat severe neurodegenerative and other genetically-driven diseases.

BiotechDeep Tech

Co-investorsGVGV (Google Ventures)OROrbiMedPAPanacea VentureCOCowen Healthcare InvestmentsREREDMILE

First Light Fusion develops fusion energy technology through experimental validation of projectile-based fusion concepts and computational modeling for inertial confinement fusion applications.

CleantechDeep TechEnergyOxfordshire, GB

Yiannis Ventikos(Founder)Nicholas Hawker(Founder)

Co-investorsSASalica InvestmentsIPIP Group

FluoRok, a spin-out of the University of Oxford, develops patented fluorinating technologies to produce fluorochemicals such as Li-ion battery electrolytes, agrochemicals, and pharmaceutical ingredients without generating toxic hydrofluoric acid.

CleantechDeep TechNew Materials

GPGabriele Pupo(CEO & Founder)inVGVéronique Gouverneur(Founder)in

Co-investorsEXExcellis HoldingGGGGFGRGreen Generation FundBUBusiness Growth FundCLClub degli InvestitoriEPePlanet Capital

Fractile designs processors for AI acceleration, offering the next generation of computing hardware.

AI & Machine LearningDeep TechHardwareSemiconductorsBristol, GB

WGWalter Goodwin(Founder & CEO)in

Co-investors0101 AdvisorsACAccelFAFactorial FundsFEFelicis VenturesGIGigascale CapitalINInovia Capital+10 more

Genomics builds a genotype-phenotype database and genetic risk-prediction tools used to support pharmaceutical drug discovery and clinical trials, as well as population health management and clinical decision support for healthcare providers.

AI & Machine LearningBiotechDigital HealthHealthtechOxford, GB

PDPeter Donnelly(Founder)inDr Chris Spencer(Founder)Dr Gerton Lunter(Founder)Gilean McVean(Founder)Professor Gil McVean(Founder)Professor Sir Peter Donnelly(Founder)

Co-investorsF-F-Prime CapitalFOForesite CapitalSASalica InvestmentsIPIP Group

Greywolf is a clinical-stage biotech developing antigen modulation therapies, including oral small molecules in Phase 1/2 trials, for people with cancers and autoimmune disorders.

BiotechDigital HealthHealthtechMedical DevicesOxford, GB

PJPeter Joyce(Co-founder)inTMTom McCarthy(Co-founder)in

Co-investorsANAndera PartnersCACanaan PartnersPFPfizer Venture InvestmentsBRBritish Patient CapitalEAEarlybird Venture CapitalPFPfizer Ventures

Delivering single cells to advance research and medicine

Oxford, GB

Michael Lutzin

Co-investorsFUFuture Planet CapitalOXOxford Investment Opportunity Network (OION)

Living Optics develops hyperspectral imaging cameras and software that enable users to capture and analyze hidden details in images across applications in food, healthcare, security, and industrial markets.

AI & Machine LearningDeep TechHardwareMedical DevicesOxford, GB

Co-investorsOCOctopus Ventures

Marley Health combines veterinary and human healthcare expertise with machine learning and technology to develop healthcare solutions.

AI & Machine LearningConsumerHealthtechMedical Devices

Nate Notwell(Co-founder & CEO)DADr Amanda Boag(Co-founder & CMO)Dr Jenny Wilshaw(Co-founder & Head of Data)PDProf David Clifton(Co-founder & Technology Advisor)

Mind Foundry develops deployed AI and machine learning systems for high-risk, high-complexity operational domains, including defense applications such as multi-sensor data fusion for battlespace situational awareness and threat-signature analysis.

AI & Machine LearningDeep TechDefense Tech

SRStephen Roberts(Co-founder)inMOMichael Osborne(Co-founder)

Co-investorsPAParkwalk Advisors

Mixergy manufactures smart hot water cylinders with patented heating technology and machine learning controls that reduce energy consumption by up to 40%.

CleantechClimate TechEnergyHardwareIoTUK, GB

Pete Armstrong(Founder)Ren Kang(Founder)

Co-investorsEDEDP VenturesIPIP GroupKIKiko Ventures

NavLive provides a handheld scanning device and cloud platform that captures point clouds and generates 2D floor plans, elevations, and sections in real time using multi-sensor SLAM tracking and AI feature detection.

AI & Machine LearningConstruction TechHardwarePropTech

DWDavid Wisth(Founder)in

Co-investorsCLClearance Venture PartnersOXOxfordSOSOSVTRTrimble Ventures

Nucleome develops 3D genomics technology to map genetic variants in the non-coding genome to the genes they dysregulate, with applications in understanding inflammatory diseases and discovering therapeutic targets.

AI & Machine LearningBiotechDeep Tech

Co-investorsM M VenturesPFPfizer Venture InvestmentsBRBritish Patient CapitalJJJJDCPFPfizer Ventures

nVisiq develops passive 3D perception systems designed for long-range, high-resolution sensing that operates across varied and difficult environments.

AI & Machine LearningDeep TechHardware

Co-investorsCECelero Ventures Ltd.

ONI develops the Nanoimager, an automated super-resolution imaging system.

BiotechDeep TechHardwareMedical DevicesOxford, GB

PSPaul Scagnetti(Chief Executive Officer)in

Co-investorsANAnjostARARCH Venture PartnersARArtis VenturesFUFuture Planet CapitalOXOxford Technology ManagementVEVertical Venture Partners+6 more

Orbit Discovery provides peptide discovery solutions for pharmaceutical and biotechnology companies, serving both large pharmaceutical firms and smaller biotech enterprises.

AI & Machine LearningBiotechDeep TechHealthtechOxford, GB

NBNeil Butt(CEO)in

Co-investorsFUFuture Planet CapitalOXOxford Technology ManagementPEPerivoli InnovationsBOBorealis Ventures

ORCA Computing develops full-stack photonic quantum computing systems, including on-premises hardware and software tools, for research institutions, government bodies, and industry applications such as generative AI, machine learning, and optimisation.

AI & Machine LearningDeep TechHardwareQuantum ComputingLondon, GB

IWIan Walmsley(Founder)inRMRichard Murray(Founder)inJNJosh Nunn(Founder)inPNPer Nyberg(Chief Commercial Officer)inMPMike Piraino(Chief Operating Officer)TNThien-An Nguyen(Chief Technology Officer)in

Co-investorsINInnovating CapitalOCOctopus VenturesPEPerscitus LLPQUQuantonationVEVerve VenturesATAtmos capital

Oxford Flow manufactures precision valves and regulators using a single-piston design for oil & gas, hydrogen, and water infrastructure.

Advanced ManufacturingCleantechEnergyHardwareOxford, GB

Co-investorsENEnergy Impact PartnersFUFuture Planet CapitalBPbp ventures

Oxford Ionics develops trapped-ion quantum computers using proprietary Electronic Qubit Control technology, designed for businesses to deploy quantum computing applications.

Deep TechHardwareQuantum Computing

Co-investorsOXOxford University Innovation2X2xNBRBraavos CapitalLALansdowne PartnersPRProsus VenturesPRProvidence Investment Company Limited

Oxford Semantic Technologies develops RDFox, an in-memory knowledge graph and semantic reasoning engine that uses logic-based inference to deduce new facts and deliver explainable, auditable results for AI applications.

AI & Machine LearningData & InfrastructureDeep TechOxford, GB

IHIan Horrocks(Co-founder)inPCPeter Crocker(Founder)in

Perspectum develops digital medical technology and diagnostics using multiparametric MRI to assess and diagnose chronic systemic diseases including liver disease, long COVID, diabetes, and cancer for clinicians and patients.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesOxford, GB

Rajarshi Banerjee(CEO)in

Co-investorsBLBlue Venture FundsBRBritish Patient CapitalHEHealthQuest CapitalSASandbox Industries

PQShield develops post-quantum cryptography (PQC) products, including optimized software libraries, SDKs, OpenSSL integration layers, and lattice-based hardware IP cores, to help organizations migrate systems to quantum-resistant cryptography.

CybersecurityDeep TechQuantum ComputingSemiconductors

Co-investorsBYBY Venture PartnersCRCrane Venture PartnersKIKindred CapitalADAdditionCHChevron Technology Ventures

Prolific operates a platform that connects research teams with a vetted pool of participants to collect high-quality human-powered data at scale, used for academic and industry research as well as developing and training AI models.

AI & Machine LearningData & InfrastructureEnterprise SoftwareMarketplacesSaaSLondon, GB

PBPhelim Bradley(CTO)inSam Harman(Director)Enrico D'Angelo(Director)Meenakshi Parameshwaran(Data Scientist)Matt Tuplin(Vice President of Engineering)Chloe Sheppard(Talent Manager)

Co-investors1010xvaluepartnersY Y CombinatorALAltaclub VCALAltaIR CapitalPAPartech VenturesPIPioneer

Prolific operates an online platform connecting researchers and AI/ML developers with verified human participants who complete paid studies, providing human data and feedback for research and for AI tasks like preference tuning, safety evaluations, and benchmarks.

AI & Machine LearningData & InfrastructureMarketplaces

Co-investorsPAPartech VenturesPIPioneer

Proxisense develops high-performance sensors for monitoring manufacturing processes and diagnostics, with origins in aerospace and defence applications.

Advanced ManufacturingDeep TechHardwareIoTMedical DevicesOxford, GB

PVPaul Vickery(Founder and Chairman)KCKam Chana(Founder and NED)

Co-investorsFUFuture Planet CapitalPAParkwalk Advisors

Quantum Motion develops utility-scale quantum computers using silicon spin-qubit architecture compatible with standard semiconductor manufacturing processes and existing foundry supply chains.

Deep TechQuantum ComputingSemiconductors

Co-investorsBOBosch VenturesDCDCVC (Data Collective)INInkefOCOctopus VenturesSOSony Ventures CorporationBRBritish Business Bank+2 more

RQ Bio discovers and develops long-acting monoclonal antibodies (LAAbs) targeting seasonal influenza to provide protection against severe viral disease.

BiotechHealthtech

Co-investorsFRFrazier Life SciencesLILifeArc VenturesWEWellington ManagementEQEQT Life SciencesFOForbionMOMonograph Capital Partners+1 more

Spin-out from the Universities of Oxford and Munster developing a novel semiconductor chip.

VKVaysh Kewada(Founder)in

Co-investorsBOBorski FundCACambridge Innovation CapitalPEPerivoli InnovationsSISilicon CatalystAPApplied VenturesDEDeeptech Labs

Scenic Biotech develops modifier therapy, a genetic medicine approach that targets secondary functions in the genome to neutralize the impact of disease-causing mutations.

AI & Machine LearningBiotechDeep TechDigital HealthHealthtech

Co-investorsBIBioGeneration VenturesBIBioMedPartnersEIEIR VenturesINInkef

Scripta Therapeutics is a drug discovery company that maps and modulates transcription factors using AI/ML models and patient-derived disease models to identify novel therapeutics.

AI & Machine LearningBiotechDeep Tech

Co-investorsALAlbionVCAPApollo Health Ventures

A biotech company dedicated to developing new vaccines, combining scientific expertise with commercial and operational capabilities.

BiotechDeep TechHealthtechMedical DevicesCambridge, GB

MHMark Howarth(Co-founder)inSBSumi Biswas(President, Co-founder, Chief Scientific Officer)inSimon Draper(Co-founder)inJing Jin(Co-founder)in

Co-investorsGVGV (Google Ventures)BRBraavos CapitalOXOxford

Stateful builds a decision intelligence engine that turns operational requirements into optimised, adaptive missions for mobile robots, coordinating single-robot, multi-robot, and human-robot operations across changing real-world environments.

AI & Machine LearningDeep TechRobotics

KLKirsty Lloyd-Jukes(CEO & Co-Founder)inNick Hawes(Chief Scientist & Co-Founder)Bruno Lacerda(CTO & Co-Founder)inDavid Parker(Advisor & Co-Founder)

Co-investorsAMAmadeus Capital PartnersOXOxford University InnovationAMAmadeus Capital SA

T-Cypher Bio develops drugs with curative potential, focusing on antibody development, T cell biology, and TCR discovery.

AI & Machine LearningBiotechDeep Tech

Co-investorsFUFuture Planet CapitalLILifeArc VenturesPEPerivoli InnovationsMEMedicxi

Tidal Cyber develops tools and services that help enterprises adopt MITRE ATT&CK framework for threat-informed defense.

CybersecurityEnterprise Software

RGRick Gordonin

Co-investorsACAccess Venture PartnersBRBright Pixel CapitalDRDreamit VenturesGLGlasswing VenturesSTStoneMill VenturesTFTFX Capital+10 more

Valink Therapeutics develops bispecific antibody-drug conjugates (ADCs) for therapeutic applications, combining high-throughput discovery, antibody engineering, and medicinal chemistry capabilities.

AI & Machine LearningBiotechHealthtechMedical DevicesBoston, US

ASArne Scheu(Founder)inIKIrsyad Khairil(Founder)in

Co-investorsHOHoxton VenturesLOLongeVCMEMetaplanetOXOxonian VenturesP5P53 InvestRVRV Invest GmbH+9 more

Vivid provides mobile business and personal banking for European small and medium-sized companies, offering online account opening, instant transfers, interest on cash balances, cashback cards, and investment options in stocks, ETFs, and cryptocurrencies.

FintechSaaS

AEAlex Emeshev(Founder)in

Co-investorsSOSoftBank Vision FundGRGreenoaksRIRibbit Capital

Ross Hendron(Founder)in

YASA designs and manufactures axial-flux electric motors for automotive OEM customers such as Ferrari and Lamborghini, operating an axial-flux factory in Oxfordshire, UK.

Advanced ManufacturingCleantechHardwareMobility & TransportationOxford, GB

TWTim Woolmer(Founder & CTO)inJörg Miska(Chief Executive Officer)

Co-investors2424 HaymarketPAParkwalk AdvisorsINInovia Capital