Oxford Science Enterprises — Full Portfolio

PepGen develops disease-modifying therapeutics aimed at the underlying causes of serious genetic neuromuscular and neurological diseases.

BiotechHealthtechBoston, US

Joshua Resnick(Director)James McArthur(Executive Officer, Director)Heidi Henson(Director)

BoardRamin Farzaneh-Far(Director)Christopher Ashton(Director)

Co-investorsRA Capital

Oxford Quantum Circuits (OQC) develops and operates superconducting quantum computers for commercial and strategic applications, offering Quantum-Compute-as-a-Service and integrating quantum systems directly into commercial data centres.

Deep TechEnterprise SoftwareHardwareQuantum ComputingOxford, GB

Peter Leek(Founder & CSO)inGerald Mullally(CEO)Simon Phillips(CTO)Nikki Cooper(CLO)Robert Coutts(CFO)

BoardJack Boyer(Chairman of the Board)

Co-investorsBritish Business BankOxfordOxford Investment Consultants LLPUTEC

Seloxium develops a metal recovery and refining technology (branded "Selectal") used for tailings reprocessing, wastewater treatment, bulk metal recovery, and high-purity refining.

Circular EconomyCleantechDeep TechNew MaterialsTeesside, GB

Dr Christian Peters(CEO & Director)Christian Peters(CEO & Co-founder)inSteve Colley(Co-founder, Technical Advisor & Director)Nick Hankins(Co-founder, Scientific Advisor & Director)Steve van Zutphen(Co-founder, CEO Advisor)Dr Richard Dixon(CCO)

Co-investorsOxford Investment Opportunity Network (OION)

Sitryx is a biotechnology company, founded in 2018, developing therapeutics with a focus on immunometabolism.

BiotechDeep TechHealthtech

Co-investorsLongwood FundSofinnova PartnersSV Health Investors

Theolytics develops systemically deliverable immunotherapies based on oncolytic adenoviruses designed to target solid tumours and their supporting microenvironment.

BiotechHealthtech

Co-investorsEpidarex CapitalSound BioventuresTaiho Ventures, LLCM Ventures

Redefining treatment of incurable blood cancers by targeting the cells that drive them.

AlveoGene is a gene therapy company developing inhaled treatments aimed at improving outcomes for patients with rare respiratory diseases.

BiotechHealthtech

Amber Therapeutics develops medical technology focused on treating mixed urinary incontinence, advancing toward pivotal clinical trials in the US with expanded feasibility studies in Europe.

Medical Devices

Co-investorsF-Prime CapitalIntuitive VenturesLightstone VenturesNew Enterprise Associates (NEA)

Archangel builds laser (optical) communication systems that connect satellite networks in space with terrestrial networks, offering an alternative to radio frequency and subsea cable infrastructure.

Deep TechHardwareSpace Tech

Co-investorsBlackfinch VenturesOxford

Co-investorsAdvent Life Sciences

BibliU is a digital learning platform that partners with publishers to provide students affordable, instant access to course content, and offers institutions workflow automation to reduce administrative burden.

EdTechSaaS

Dave Sherwood(Co-Founder & CEO)in

Co-investorsBrick Capital VenturesGreen Shores CapitalGuinness VenturesParkwalk AdvisorsEmerge Education

Co-investorsCreative Destruction Lab (CDL)Longwall Venture Partners LLPOxford Investment Consultants LLP

Dark Blue Therapeutics is a drug discovery company developing a pipeline of first-in-class precision medicine cancer drugs targeting high unmet medical needs.

BiotechHealthtech

Alastair MacKinnonin

Diffblue builds an autonomous testing agent that generates regression unit tests at scale for enterprise codebases, working with existing AI coding platforms like GitHub Copilot and Claude Code to produce verified tests for Java and Python.

AI & Machine LearningDeveloper ToolsEnterprise Software

Co-investorsAlbionVCPerivoli Innovations

Endlyz develops small-molecule disease-modifying therapeutics targeting the ATP13A2 and ATP10B lysosomal transporters to restore endo-lysosomal function and counter neurodegeneration.

BiotechDeep TechBoston, US

Joanna Wolak(Executive Officer, Director)Jonathan Behr(Director)John Gustofson(Director)Damian Crowther(Director)Zaven Kaprielian(Executive Officer, Director)

BoardLaurence Barker(Director)

Co-investorsDementia Discovery Fund

Co-investorsPerivoli Innovations

Evox Therapeutics develops exosome-based gene editing therapies using its ExoEdit platform, which combines exosome delivery with a proprietary CRISPR-based editor to treat severe neurodegenerative and other genetically-driven diseases.

BiotechDeep Tech

Co-investorsOrbiMedPanacea VentureCowen Healthcare InvestmentsGV (Google Ventures)REDMILE

First Light Fusion develops an inertial fusion energy architecture called FLARE that separates compression and fast ignition to lower the peak power needed for fusion, aiming for a simpler and lower-cost path to commercial fusion power.

CleantechDeep TechEnergy

Co-investorsSalica Investments

FluoRok, a spin-out of the University of Oxford, develops patented fluorinating technologies to produce fluorochemicals such as Li-ion battery electrolytes, agrochemicals, and pharmaceutical ingredients without generating toxic hydrofluoric acid.

CleantechDeep TechNew Materials

Gabriele Pupo(CEO & Founder)inVéronique Gouverneur(Founder)

Co-investorsExcellis HoldingGGFGreen Generation Fund

Fractile designs processors for AI acceleration, offering the next generation of computing hardware.

AI & Machine LearningDeep TechHardwareSemiconductorsBristol, GB

Walter Goodwin(Founder & CEO)in

Co-investorsAccelFactorial FundsFelicis VenturesGigascale CapitalInovia Capital01 Advisors+3 more

Greywolf is a clinical-stage biotech developing antigen modulation therapies, including oral small molecules in Phase 1/2 trials, for people with cancers and autoimmune disorders.

BiotechDigital HealthHealthtechMedical DevicesOxford, GB

Peter Joyce(Co-founder)Tom McCarthy(Co-founder)

Co-investorsAndera PartnersCanaan PartnersPfizer Venture InvestmentsBritish Patient CapitalEarlybird Venture CapitalPfizer Ventures

Co-investorsFuture Planet CapitalOxford Investment Opportunity Network (OION)

Living Optics builds a handheld snapshot hyperspectral imaging camera and accompanying software that capture and analyze hyperspectral data at video rate.

AI & Machine LearningDeep TechHardwareOxford, GB

Co-investorsOctopus Ventures

Marley Health is a clinical health platform for pets that combines at-home and in-clinic health data with AI to provide predictive insights and proactive care recommendations.

AI & Machine LearningConsumerHealthtech

Mind Foundry develops deployed AI and machine learning systems for high-risk, high-complexity operational domains, including defense applications such as multi-sensor data fusion for battlespace situational awareness and threat-signature analysis.

AI & Machine LearningDeep TechDefense Tech

Stephen Roberts(Co-founder)Michael Osborne(Co-founder)

A therapeutics company developing checkpoint agonist antibodies for autoimmune disease treatment based on Oxford University research (exited August 2022).

Co-investorsAdvent Life SciencesMedicxiMonograph Capital PartnersSamsara BioCapital

Mixergy makes patented smart hot water cylinders that heat only the water needed, helping reduce energy bills, improve EPC scores, and support compliance for social housing, new builds, and commercial buildings.

CleantechEnergyHardware

Co-investorsKiko Ventures

Portfolio company that raised a £22.2m Series C funding round

Co-investorsParkwalk Advisors

Modelabs develops robust, continuous, remote real-time chemical sensors that use micron-scale quantum technology to reflect light through liquid samples 10,000 times for lab-grade sensitivity.

CleantechHardwareQuantum Computing

NavLive makes the Radius, a handheld LiDAR and SLAM-based scanner with AI processing that captures 2D floor plans and 3D point clouds of building sites in a single walk-through and exports them to BIM tools like Revit, AutoCAD, and ArchiCAD.

AI & Machine LearningConstruction TechHardware

David Wisth(Founder)in

Co-investorsClearance Venture PartnersOxford

Nucleome develops 3D genomics technology to map genetic variants in the non-coding genome to the genes they dysregulate, with applications in understanding inflammatory diseases and discovering therapeutic targets.

AI & Machine LearningBiotechDeep Tech

Co-investorsM VenturesPfizer Venture InvestmentsBritish Patient CapitalJJDCPfizer Ventures

OMass uses native mass spectrometry, proprietary biochemistry and custom chemistry to study drug targets and their interactions with their native biological environment outside the confounding complexity of the cell.

BiotechDeep TechHealthtech

Ros Deeganin

Co-investorsGV (Google Ventures)Sanofi Ventures

Opsydia is a laser technology company, spun out of the University of Oxford, that uses adaptive optic beam shaping to write features and optical waveguides in transparent materials such as glass.

Deep TechNew MaterialsSemiconductors

Co-investorsForesight GroupParkwalk Advisors

Orbit Discovery is a drug discovery company that participates in industry conferences focused on peptide therapeutics and GPCR-targeted drug discovery.

BiotechHealthtech

Neil Butt(CEO)

Co-investorsFuture Planet CapitalOxford Technology ManagementPerivoli Innovations

ORCA Computing develops full-stack photonic quantum computers, including its rack-mounted, air-cooled PT Series systems that use fibre-interconnected telecom and optical components for quantum-accelerated generative AI and optimisation.

AI & Machine LearningDeep TechQuantum ComputingLondon, GB

Ian Walmsley(Co-founder)Richard Murray(Co-founder, CEO)Josh Nunn(Co-founder, Chief Science Officer)

Co-investorsInnovating CapitalOctopus VenturesPerscitus LLPQuantonationVerve Ventures

Oxford Flow designs and manufactures industrial flow control valves, pressure regulators, and pilot valves using precision engineering and fluid dynamics.

Advanced ManufacturingCleantechHardware

Co-investorsEnergy Impact PartnersFuture Planet Capitalbp ventures

Oxford Ionics develops trapped-ion quantum computers using Electronic Qubit Control to integrate qubit trapping and control onto standard semiconductor chips.

Deep TechHardwareQuantum Computing

Co-investorsOxford University Innovation2xNLansdowne PartnersProsus Ventures

Oxford Semantic Technologies develops RDFox, an in-memory knowledge graph and semantic reasoning engine that uses logic-based inference to deduce new facts and deliver explainable, auditable results for AI applications.

AI & Machine LearningData & InfrastructureDeep TechOxford, GB

Ian Horrocks(Co-founder)Peter Crocker(Founder)in

PQShield develops quantum-resistant cryptography in hardware and software, including post-quantum cryptography (PQC) solutions for chips, applications, and cloud environments.

CybersecurityDeep TechQuantum Computing

Co-investorsBY Venture PartnersCrane Venture PartnersKindred CapitalAdditionChevron Technology Ventures

Prolific connects researchers, AI developers, and product teams with vetted participants for collecting high-quality human data for AI training, surveys, and behavioral research.

AI & Machine LearningData & InfrastructureEnterprise SoftwareMarketplacesSaaSLondon, GB

Phelim Bradley(Founder)in

Co-investors10xvaluepartnersY Combinator

Quantum Motion develops utility-scale quantum computers using silicon spin-qubit architecture compatible with standard semiconductor manufacturing processes and existing foundry supply chains.

Deep TechQuantum ComputingSemiconductors

Co-investorsBosch VenturesDCVC (Data Collective)Octopus VenturesRobert Bosch Venture CapitalSony Ventures CorporationBritish Business Bank+1 more

Refeyn develops mass photometers that measure the mass of individual molecules directly in solution using label-free single-molecule light scattering, providing rapid assessment of sample purity, molecular interactions, and heterogeneity.

BiotechDeep TechHardwareOxford, GB

Co-investorsHorizons VenturesOxford Technology Management

Company co-founded by Johannes Feldmann and Vaysh Kewada.

Spin-out from the Universities of Oxford and Munster developing a novel semiconductor chip.

Vaysh Kewada(Founder)in

Co-investorsCambridge Innovation CapitalPerivoli InnovationsSilicon Catalyst

Scenic Biotech develops disease-modifying therapies for patients with neurological and metabolic genetic disorders using its Cell-Seq discovery platform to identify modifier genes.

BiotechDeep TechHealthtech

Co-investorsBioMedPartnersEIR VenturesBioGeneration VenturesInkef

Snowfox Discovery is a natural hydrogen exploration company developing technology to locate and unlock naturally occurring hydrogen in the geological subsurface.

CleantechClimate TechEnergy

Daniel McMahonin

Co-investorsAP VenturesOxfordbp ventures

SpyBiotech is a clinical-stage biotech company developing vaccines against infectious diseases and cancer using its proprietary SpyTag/SpyCatcher protein "superglue" platform.

BiotechDeep TechHealthtech

Co-investorsGV (Google Ventures)

Co-investorsAmadeus Capital PartnersOxford University Innovation

T-Cypher develops drugs against novel disease-specific targets to treat patients with cancer and autoimmune diseases, focusing on immune-system-engaging medicines.

AI & Machine LearningBiotechDeep Tech

Co-investorsFuture Planet CapitalLifeArc VenturesPerivoli Innovations

Tidal Cyber develops tools and services that help enterprises adopt MITRE ATT&CK framework for threat-informed defense.

CybersecurityEnterprise Software

Rick Gordonin

Co-investorsAccess Venture PartnersBright Pixel CapitalDreamit VenturesGlasswing VenturesStoneMill VenturesTFX Capital+8 more

Ultromics develops FDA-cleared AI software (EchoGo Heart Failure and EchoGo Amyloidosis) that analyzes routine echocardiograms to help clinicians identify patients with HFpEF and screen for cardiac amyloidosis.

AI & Machine LearningDigital HealthMedical Devices

Ross Upton(CEO & Founder)

Co-investorsFuture Planet CapitalGV (Google Ventures)Nina CapitalNovaCapitalOptum VenturesALLEGIS CAPITAL

Ross Hendron(Founder)in

YASA develops axial flux electric motors ('eMotors') and control systems for electric vehicles and other electrification applications, using a proprietary Yokeless And Segmented Armature design that reduces motor size and weight while increasing power and torque density.

CleantechHardwareMobility & TransportationOxford, GB

Tim Woolmer(CTO & Founder)

Co-investors24 HaymarketParkwalk AdvisorsInovia Capital