Catalio Capital Management — Full Portfolio

Alentis is a biotech company developing therapies for chronic liver disease, fibrosis, and cancer based on the molecular biology of liver disease.

AI & Machine LearningBiotechHealthtechMedical DevicesBasel, CH

Thomas Baumert(Founder)inMark Pruzanski(Chief Executive Officer)inLuigi Manenti(Chief Medical Officer)inJon Freve(Chief Financial Officer)inBryan Yoon(General Counsel and Chief Administrative Officer)inAditya Venugopal(Chief Business Officer)in

Co-investorsAvego BioScience CapitalBioMedPartnersFrazier Life SciencesJeito CapitalLongitude CapitalNovo Holdings+5 more

Iambic develops AI technologies for drug discovery, using a high-throughput experimental platform to design small-molecule medicines and advance a pipeline of clinical candidates for cancers such as HER2-driven, breast, and ovarian tumors.

AI & Machine LearningBiotechDeep TechSan Diego, US

Tom Miller(Co-Founder & CEO)inFred Manby(Co-Founder & CTO)inThomas Miller(Founder)inNeil Josephson(Chief Medical Officer)inPete Olson(Chief Scientific Officer)inMichael Secora(Chief Financial Officer and Chief Corporate Development Officer)in

Co-investorsAbingworthAscenta CapitalAlumni VenturesCatalio Capital Management, LPCoatue ManagementEisai Innovation, Inc.+4 more

Orasis is a pharmaceutical company developing drugs for the eye, operating in the ophthalmology and eyecare space.

BiotechHealthtechMedical Devices

Co-investorsArboretum VenturesMaverick Ventures IsraelVisionary VenturesJohnson & Johnson Innovation – JJDCLifeSci Venture PartnersSequoia Capital+1 more

Spiral Therapeutics is a clinical-stage pharmaceutical company developing therapies for balance disorders and hearing loss using its Minimally Invasive Cochlear System (MICS) drug delivery platform.

BiotechDigital HealthHealthtechMedical DevicesSouth San Francisco, US

Hugo Peris(Founder & CEO)inEugene de Juan(Executive Officer, Director)Lawrence Fritz(Director)

BoardWARREN THALER(Director)JEAN-FREDERIC PAULSEN(Director)Guy Nohra(Director)in

Co-investorsAlta PartnersEsperante Ventures

HealthtechWaltham, US

Clinton Earl Carnell Jr.(Executive Officer, Director)Irina Erenburg(Manager)inJay Bhawalkar(Executive Officer)Richard Rox Anderson(Director)

BoardDaniel Browne(Director)Mary Fisher(Director)

Cartography develops antibody-based cancer therapies using single-cell sequencing and computational biology to identify precise cellular targets.

AI & Machine LearningBiotechDeep TechMedical DevicesSouth San Francisco, US

Max Mumbach(Founding Scientist, Target Discovery)inJeffrey Verboon(Founding Scientist, Computational Biology)inAnsu Satpathy(Founder)Kevin Parker, PhD(Chief Executive Officer, Board Director; co-founder)Ansuman Satpathy, MD, PhD(Co-founder; Board Director)Howard Chang(Co-founder)in

Co-investors8VCAndreessen HorowitzArtis VenturesGlobal BioAccess FundHAWKTAILPfizer Venture Investments+6 more

Character Bio is a patient-driven therapeutics company that combines genomics, longitudinal clinical and imaging data, and machine learning to identify genetic drivers of disease progression and develop new treatments, with a focus on polygenic diseases.

AI & Machine LearningBiotechDigital HealthJersey City, US

Cheng Zhang(CEO, Co-Founder)inMarcel van der Brug(Scientific Advisor, Co-Founder)inNick Johnson(Technology Advisor, Co-Founder)inDaniel Elgort(Chief Data and Analytics Officer)inLaura Carter(Chief Scientific Officer)inRobert Kim(Chief Medical Officer)in

Co-investorsaMoonSanofi VenturesInnovation EndeavorsLuma GroupCantos VenturesCatalio Capital Management, LP+3 more

BiotechJersey City, US

Henry Rath(Executive Officer)Susan Orr(Executive Officer)inClarke Atwell(Executive Officer, Director)Stephen Brady(Executive Officer, Director)Michael Dybbs(Director)Matt Hobson(Director)

Co-investorsNovo HoldingsSamsara BioCapitalSofinnova Ventures

Clasp Therapeutics develops off-the-shelf precision T cell engagers (its proprietary pHLАre molecules) that target mutant peptide-HLA complexes displayed on cancer cells, directing T cells to destroy tumors carrying common driver mutations such as KRas.

BiotechHealthtechCambridge, US

Co-investorsCatalio Capital Management, LPCure VenturesVivo CapitalNovo HoldingsThird Rock Ventures

Cortex Robot builds datasets for embodied AI and robotics, including egocentric video data from real workplaces and robot trajectories for training physical intelligence systems.

Advanced ManufacturingAI & Machine LearningData & InfrastructureRoboticsSan Francisco, US

Lucas Ngoo(Founder)in

Co-investorsTranspose Platform ManagementY CombinatorGV (Google Ventures)Lux Capital

Ensoma is a genomic medicine company developing a platform for in vivo engineering of hematopoietic stem cells (HSCs), combining an off-the-shelf delivery system with a gene engineering toolkit intended to treat diseases with a one-time treatment.

BiotechHealthtechMedical DevicesBoston, US

Albert Seymour(Director)

BoardKush Parmar(Executive Officer, Director)Paula Soteropoulos(Director)Stephen Knight(Director)

Co-investors5AM VenturesAju IB Invesment CorporationCatalio Capital Management, LPDelos CapitalF-Prime CapitalSolasta Ventures+7 more

Extracellular is a biomanufacturing company that helps cell-based product developers in cultivated meat, plant cell culture, and bioactives accelerate discovery, overcome production challenges, and commercialize their products.

Advanced ManufacturingBiotechFoodTechNew Materials

Will Milligan(CEO & Founder)in

Co-investorsBig Idea VenturesFFFNewland SyndicateUnruly Capital5AM VenturesAgent Capital+8 more

Cambridge, MA biotechnology company developing injectable synthetic biomarkers for noninvasive disease staging and treatment monitoring.

BiotechCambridge, US

Gabriel Kwong(Executive Officer)Sirshendu Roopom Banerjee(Executive Officer)

BoardTheresia Guow(Director)Amy Schulman(Director)inStan Lapidus(Director)

Co-investorsGreatPoint VenturesAcrew CapitalAspect VenturesDns CapitalNew Leaf Venture PartnersPolaris Partners+2 more

Imbria Pharmaceuticals develops novel cardiovascular disease treatments that target cardiac energy metabolism, with a lead drug candidate, ninerafaxstat, in clinical trials for non-obstructive hypertrophic cardiomyopathy.

BiotechDigital Health

Alvin Shih(CEO)inAlbert M. Kim(Chief Medical Officer)in

Co-investorsAN Venture PartnersRA CapitalSanofi VenturesSV Health Investors

BiotechBoston, US

Pavan Cheruvu(Director)Alvin Shih(Executive Officer, Director)inKomal Joshi(Executive Officer)inPieter Boelhouwer(Director)David-Alexandre C. Gros(Executive Officer, Director)

BoardCharles Dunn(Director)

Co-investorsRA CapitalSV Health Investors

Chronus is a platform that connects employees for guided, AI-assisted conversations focused on career development, mentoring, community building, and change adoption in enterprise organizations.

AI & Machine LearningEnterprise SoftwareFuture of WorkHR TechSaaSNew York, US

Aaron Hurst(Founder)in

Co-investorsVoyager CapitalAlly Bridge GroupAmed VenturesAscension VenturesBain Capital Life SciencesDelos Capital+2 more

Insightec develops Exablate Neuro, an MRI-guided focused ultrasound platform that treats Essential Tremor and tremor-dominant Parkinson's Disease through an incision-free outpatient procedure.

HealthtechMedical DevicesTirat Carmel

Roni Karie(Vice President - Finance)Shirel Aroshase(Vice President - Human Resources)inEyal Zadicario(General Manager)inMenashe Frank(Vice President - Legal)inJun (Jim) Tao(Chief Operating Officer)inMaurice R. Ferre(Chairman and Chief Executive Officer)in

Co-investorsCatalio Capital Management, LPExigent CapitalGEOCJazzya InvestmentsKoch Disruptive TechnologiesKrillion Ventures+7 more

Lassen Therapeutics is a biotechnology company developing therapeutics targeting IL-11, with a pipeline focused on immune and fibrotic diseases.

Biotech

David King(Co-Founder & CSO)inMaria Fardis(CEO)inCadmus C. Rich(Chief Medical Officer)inElaine Stracker(General Counsel)in

Co-investorsAlta PartnersCatalio Capital Management, LPDC Investment PartnersLongitude CapitalLongwood FundBiotechnology Value Fund+2 more

NextPoint is a precision therapeutics company developing cancer treatments targeting the B7-H7/HHLA2 axis, including a T-cell engager, an antibody-drug conjugate with proprietary linker technology, and a multi-functional checkpoint inhibitor.

BiotechHealthtechAustin, US

Gordon Freeman(Scientific Founder)XingXing Zang(Scientific Founder)inIvan Cheung(Chief Executive Officer)inLeena Gandhi(Chief Medical Officer)inTatiana Novobrantseva(Chief Scientific Officer)inAxel Hoos(Director)

Co-investorsCatalio Capital Management, LPMPM BioImpactSanofi VenturesInvusLeaps by BayerSixty Degree Capital

Noetik builds AI models to identify cancer patients most likely to respond to treatments and to discover new oncology drug targets.

AI & Machine LearningBiotechHealthtechSouth San Francisco, US

Jacob Rinaldi(Executive Officer, Director, Promoter)inRonald Alfa(Executive Officer, Director, Promoter)Ron Alfa, MD, PhD(Founder)in

BoardJames Hardiman(Director)inAmy Schulman(Director)in

Co-investors11.2 CapitalBreakout VenturesLinearis VenturesNorth South VenturesDCVC (Data Collective)EPIC VENTURES+2 more

Tukwila, US

Robert Andrade(Executive Officer, Director, Promoter)Maurice J. Costantini(Executive Officer, Director, Promoter)

Co-investors8VCAndreessen HorowitzSV Angel

BiotechSouth San Francisco, US

Watson Debi(Director)Anne Rubin(Executive Officer, Director)Kirsten Angela Macfarlane(Executive Officer, Director, Promoter)Cameron Wheeler(Director)Randall Olson(Director)Robert Jackson(Director)

Co-investorsCatalio Capital Management, LPBraidwellDeerfield Management CompanyGV (Google Ventures)Johnson & Johnson Innovation – JJDC

Pheast Therapeutics develops immunotherapies targeting cancer, building on foundational research from Stanford's stem cell research institute.

BiotechHealthtechMedical DevicesRedwood City, US

Irv Weissman(Cofounder, Scientific Advisor, Board Director)Ravi Majeti(Cofounder, Scientific Advisor, Board Observer)Amira Barkal(Principal Founder, Scientific Advisor, Board Director)inRoy Maute(Cofounder & Chief Executive Officer)in

BoardJacob Vogelstein(Director)Steven Gillis(Director)in

Co-investorsARCH Venture PartnersCatalio Capital Management, LPAlexandria

ProSomnus offers oral appliance devices for treating obstructive sleep apnea and snoring, positioned as an alternative to CPAP machines.

Digital HealthHealthtechMedical DevicesWellness & FitnessPleasanton, US

Leonard Liptak(Executive Officer, Director)Sung Kim(Executive Officer)Jason Orchard(Director)Steven Pacelli(Director)Heather Rider(Director)Laing Rikkers(Executive Officer, Director)

Co-investorsCatalio Capital Management, LPSpring Mountain Capital

Ratio Therapeutics develops radiopharmaceuticals for oncology, working on targeted radiochemistry, discovery, and preclinical and clinical development.

BiotechHealthtechMedical DevicesBoston, US

John Babich(Director, President & Chief Scientific Officer)inJack Hoppin(Chairman & Chief Executive Officer)inWilliam Cupelo(Chief Business Officer)Matthias Friebe(Chief Technology Officer)inScott Holbrook(Chief Commercial and Manufacturing Officer)inJacob Hesterman(Chief Data Officer)in

Rhapsogen is developing a precision biologic therapy aimed at treating autoimmune diseases, focused on efficacy, safety, and durability.

BiotechHealthtech

Co-investorsCatalio Capital Management, LP

HealthtechCambridge, US

Rahul Dhanda(Executive Officer, Director)James Collins(Director)David Walt(Director)in

BoardIssi Rozen(Director)in

Co-investorsCatalio Capital Management, LPIllumina VenturesGood VenturesGV (Google Ventures)Northpond VenturesNovalis LifeSciences

Somethings connects teenagers with peer mentorship support to address gaps in mental health access in the United States.

Digital HealthHealthtechMental HealthWellness & Fitness

Patrick Gilligan(Founder & CEO)in

Co-investorsCoalition OperatorsTau VenturesGaingelsGeneral CatalystMVP VenturesPlug and Play Ventures+1 more

Star Therapeutics develops treatments aimed at addressing real-world patient needs.

BiotechSouth San Francisco, US

Adam Rosenthal(Founder & CEO)inNancy Stagliano(Director)Michelle Carpenter(Executive Officer)Sandip Panicker(Executive Officer)Scott Robertson(Executive Officer)inGary Patou(Executive Officer)in

Co-investorsFrazier Life SciencesOrbiMedRA CapitalSanofi VenturesSofinnova VenturesAgent Capital+8 more

Syndeio Biosciences is a synapse-focused biotech developing precision neurotherapeutics for neuropsychiatric, mental health, and cognitive disorders such as depression and Alzheimer's.

AI & Machine LearningBiotechDigital Health

Co-investorsEvolution VC PartnersTenmilePalo Santo

Visby offers an FDA-authorized at-home PCR test kit for women's sexual health that detects chlamydia, gonorrhea, and trichomoniasis from a single swab, delivering private results via a mobile app in about 30 minutes with included same-day telehealth for positive results.

ConsumerDigital HealthFemTechHealthtechMedical DevicesTokyo, US

Adam de la Zerda(Founder)in

Co-investors+ND Capital1809 CapitalAmplify PartnersArtiman VenturesG Vision CapitalKhosla Ventures+5 more

BiotechHealthtechDurham, US

Xiling Shen(Executive Officer, Director, Promoter)David Shiaowen(Director)William Roy Smythe(Executive Officer, Director)

BoardAlaa Halawa(Director)John de Koning(Director)

Co-investorsAlexandriaAlix VenturesEQT Life SciencesFelicis VenturesMC Healthcare VenturesMubadala Capital+2 more