Catalio Capital Management — Full Portfolio

Neumora is a clinical research company developing investigational medications, with a focus on conducting clinical trials to obtain regulatory approval and make treatments available to patients.

BiotechDeep TechDigital HealthMedical DevicesWatertown, US

PLPaul L. Berns(Chairman and Chief Executive Officer)Joshua Pinto(Executive Officer)TTTamara Tompkins(Executive Officer)inKari Stefansson(Director)MHMaykin Ho(Director)AHAlaa Halawa(Director)

Co-investorsARARCH Venture PartnersCACatalio Capital Management, LPF-F-Prime CapitalK2K2 HealthVenturesMEMercury FundPRPremier Partners+12 more

Alentis is a biotech company developing therapies for chronic liver disease, fibrosis, and cancer based on the molecular biology of liver disease.

AI & Machine LearningBiotechHealthtechMedical DevicesBasel, CH

TBThomas Baumert(Founder)inMPMark Pruzanski(Chief Executive Officer)inLMLuigi Manenti(Chief Medical Officer)inJFJon Freve(Chief Financial Officer)inBYBryan Yoon(General Counsel and Chief Administrative Officer)inAVAditya Venugopal(Chief Business Officer)in

Co-investorsAVAvego BioScience CapitalBIBioMedPartnersFRFrazier Life SciencesJEJeito CapitalLOLongitude CapitalNONovo Holdings+5 more

Iambic develops AI technologies for drug discovery, using a high-throughput experimental platform to design small-molecule medicines and advance a pipeline of clinical candidates for cancers such as HER2-driven, breast, and ovarian tumors.

AI & Machine LearningBiotechDeep TechSan Diego, US

TMTom Miller(Founder)inFred Manby(Founder)inCZChao Zhang(Executive Officer)inTabbert Teng(Executive Officer)NJNeil Josephson(Chief Medical Officer)inPOPete Olson(Chief Scientific Officer)in

Co-investorsASAscenta CapitalABAbingworthALAlumni VenturesCACatalio Capital Management, LPCOCoatue ManagementEIEisai Innovation, Inc.+7 more

Orasis is a pharmaceutical company developing drugs for the eye, operating in the ophthalmology and eyecare space.

BiotechHealthtechMedical Devices

Co-investorsARArboretum VenturesMAMaverick Ventures IsraelVIVisionary VenturesJOJohnson & Johnson Innovation – JJDCLILifeSci Venture PartnersSESequoia Capital+1 more

Spiral Therapeutics is a clinical-stage pharmaceutical company developing therapies for balance disorders and hearing loss using its Minimally Invasive Cochlear System (MICS) drug delivery platform.

BiotechDigital HealthHealthtechMedical DevicesSouth San Francisco, US

HPHugo Peris(Founder & CEO)inEDEugene de Juan(Executive Officer, Director)Lawrence Fritz(Director)

BoardWARREN THALER(Director)JEAN-FREDERIC PAULSEN(Director)GNGuy Nohra(Director)in

Co-investorsINInveready Technology Investment GroupLILifelinkSTStartXALAlta PartnersCACamden PartnersESEsperante Ventures

Nicolas Tilmans(Founder)

Co-investorsAIAir Street CapitalLULux Capital

Cartography develops antibody-based cancer therapies using single-cell sequencing and computational biology to identify precise cellular targets.

AI & Machine LearningBiotechDeep TechMedical DevicesSouth San Francisco, US

MMMax Mumbach(Founding Scientist, Target Discovery)inJVJeffrey Verboon(Founding Scientist, Computational Biology)inASAnsu Satpathy(Founder)KPKevin Parker, PhD(Chief Executive Officer, Board Director; co-founder)ASAnsuman Satpathy, MD, PhD(Co-founder; Board Director)HCHoward Chang(Founder)in

Co-investors8V8VCANAndreessen HorowitzARArtis VenturesCACatalio Capital Management, LPFIFinchley Healthcare VenturesGLGlobal BioAccess Fund+9 more

Character Bio is a patient-driven therapeutics company that combines genomics, longitudinal clinical and imaging data, and machine learning to identify genetic drivers of disease progression and develop new treatments, with a focus on polygenic diseases.

AI & Machine LearningBiotechDigital HealthJersey City, US

CZCheng Zhang(CEO, Co-Founder)inMarcel van der Brug(Scientific Advisor, Co-Founder)inNick Johnson(Technology Advisor, Co-Founder)inDEDaniel Elgort(Chief Data and Analytics Officer)inLCLaura Carter(Chief Scientific Officer)inRobert Kim(Chief Medical Officer)in

Co-investorsAMaMoonLULuma GroupSASanofi VenturesINInnovation EndeavorsCACantos VenturesCACatalio Capital Management, LP+5 more

Claris Bio develops biologic therapies for sight-threatening eye diseases, with a current focus on bringing CSB-001, a novel treatment for patients with limbal stem cell deficiency, through clinical development and to market.

BiotechHealthtechMedical DevicesJersey City, US

CAClarke Atwell(Co-Founder and Chief Operating Officer)inHenry Rath(Executive Officer)SOSusan Orr(Executive Officer)inStephen Brady(Executive Officer, Director)Michael Dybbs(Director)Matt Hobson(Director)

Co-investorsCACatalio Capital Management, LPRARA CapitalSOSofinnova VenturesNONovo HoldingsSASamsara BioCapital

Clasp Therapeutics develops off-the-shelf precision T cell engagers (its proprietary pHLАre molecules) that target mutant peptide-HLA complexes displayed on cancer cells, directing T cells to destroy tumors carrying common driver mutations such as KRas.

BiotechHealthtechCambridge, US

Co-investorsCACatalio Capital Management, LPCUCure VenturesVIVivo CapitalBRBrightEdgeNONovo HoldingsTHThird Rock Ventures

Cortex Robot builds datasets for embodied AI and robotics, including egocentric video data from real workplaces and robot trajectories for training physical intelligence systems.

Advanced ManufacturingAI & Machine LearningData & InfrastructureRoboticsSan Francisco, US

LNLucas Ngoo(Founder)in

Co-investorsPIPioneerTRTranspose Platform ManagementY Y Combinator46468 Capital50500 GlobalBLBlast.Club+14 more

Biotechnology company using multiplex gene editing to develop genetically engineered porcine organs for human transplantation.

BiotechBrookline, US

Luhan Yang(President, Secretary and Treasurer)Geoff MacKay(Chief Executive Officer)

BoardGMGeorge M. Church(Director)

Co-investorsALAlta PartnersARARCH Venture PartnersCACatalio Capital Management, LPHBHBM Healthcare InvestmentsHBHBM PartnersKHKhosla Ventures+12 more

Ensoma is a genomic medicine company developing a platform for in vivo engineering of hematopoietic stem cells (HSCs), combining an off-the-shelf delivery system with a gene engineering toolkit intended to treat diseases with a one-time treatment.

BiotechHealthtechMedical DevicesBoston, US

Albert Seymour(Director)

BoardKPKush Parmar(Executive Officer, Director)inPSPaula Soteropoulos(Director)SKStephen Knight(Director)in

Co-investors5A5AM VenturesAJAju IB InvestmentCACatalio Capital Management, LPDEDelos CapitalF-F-Prime CapitalSOSolasta Ventures+10 more

Enveda operates a drug-discovery platform that analyzes natural samples—primarily plant-derived molecules—using mass spectrometry, AI foundation models, and automated high-throughput labs to identify their chemical structures and therapeutic properties.

AI & Machine LearningBiotechDeep TechBoulder, US

VCViswa Colluru(Founder)inDaniel Wee(Executive Officer)Pieter Dorrestein(Founder)Viswa Colluru Pieter Dorrestein(Founder)

BoardRohit Sharma(Director)ZDZavain Dar(Director)in

Co-investorsAIAir Street CapitalBOBoulder VenturesCACatalio Capital Management, LPCOCox EnterprisesFPFPVHUHummingbird Ventures+20 more

Evvy is an AI-powered precision medicine platform using vaginal microbiome testing and analysis to diagnose and treat women's health conditions including vaginal health, fertility, and menopause.

AI & Machine LearningDigital HealthFemTechHealthtech

PJPriyanka Jain(Founder)inLBLaine Bruzek(Founder)inPNPita Navarro(Founder)in

Co-investorsALAlumni VenturesAMAmboy Street VenturesBOBoxGroupFOForeground CapitalFOForerunner VenturesGEGeneral Catalyst+9 more

Extracellular is a biomanufacturing company that helps cell-based product developers in cultivated meat, plant cell culture, and bioactives accelerate discovery, overcome production challenges, and commercialize their products.

Advanced ManufacturingBiotechFoodTechNew Materials

WMWill Milligan(CEO & Founder)in

Co-investorsBIBig Idea VenturesFFFFFNENewland SyndicateUNUnruly Capital5A5AM VenturesAGAgent Capital+8 more

Georgiamune is a biopharmaceutical company developing targeted immunomodulator drugs that activate or down-modulate immune signaling pathways to treat cancer and autoimmune diseases.

BiotechDeep TechHealthtechGaithersburg, US

SNSamir N. Khleif(Founder & CEO)inRIRamy Ibrahim(Chief Medical and Strategy Officer)inMMMikayel Mkrichyan(Senior Vice President of Science and Discovery)SSSarah Sharman(Vice President of IP Legal Affairs)

BoardSPSean Parker(Director)EVElena Viboch(Director)in

Co-investorsCACatalio Capital Management, LPGEGeneral CatalystHAHAWKTAILLALauder PartnersPRPrevail Venture CapitalALAlexandria+3 more

Cambridge, MA biotechnology company developing injectable synthetic biomarkers for noninvasive disease staging and treatment monitoring.

BiotechCambridge, US

GKGabriel Kwong(Executive Officer)inSBSangeeta BhatiainRBRoopom Banerjee(Executive Officer)in

BoardTGTheresia Gouw(Director)inASAmy Schulman(Director)SLStan Lapidus(Director)in

Co-investorsGRGreatPoint VenturesACAcrew CapitalARARCH Venture PartnersASAspect VenturesCRCRV (Charles River Ventures)DNDns Capital+7 more

Imbria Pharmaceuticals develops novel cardiovascular disease treatments that target cardiac energy metabolism, with a lead drug candidate, ninerafaxstat, in clinical trials for non-obstructive hypertrophic cardiomyopathy.

BiotechDigital Health

ASAlvin Shih(CEO)inAMAlbert M. Kim(Chief Medical Officer)in

Co-investorsANAN Venture PartnersCACatalio Capital Management, LPRARA CapitalSASanofi VenturesSVSV Health Investors

Chronus is a platform that connects employees for guided, AI-assisted conversations focused on career development, mentoring, community building, and change adoption in enterprise organizations.

AI & Machine LearningEnterprise SoftwareFuture of WorkHR TechSaaSNew York, US

AHAaron Hurst(Founder)in

Co-investorsEMEmpire AngelsVOVoyager CapitalALAlly Bridge GroupAMAmed VenturesASAscension VenturesBABain Capital Life Sciences+4 more

Insightec develops Exablate Neuro, an MRI-guided focused ultrasound platform that treats Essential Tremor and tremor-dominant Parkinson's Disease through an incision-free outpatient procedure.

HealthtechMedical DevicesTirat Carmel

Roni Karie(Vice President - Finance)SAShirel Aroshase(Vice President - Human Resources)inEZEyal Zadicario(General Manager)inMenashe Frank(Vice President - Legal)inJ(Jun (Jim) Tao(Chief Operating Officer)inMRMaurice R. Ferre(Chairman and Chief Executive Officer)in

Co-investorsCACatalio Capital Management, LPEXExigent CapitalGEGEOCJAJazzya InvestmentsKOKoch Disruptive TechnologiesKRKrillion Ventures+6 more

Lassen Therapeutics is a biotechnology company developing therapeutics targeting IL-11, with a pipeline focused on immune and fibrotic diseases.

Biotech

DKDavid King(Co-Founder & CSO)inMFMaria Fardis(CEO)inCCCadmus C. Rich(Chief Medical Officer)inESElaine Stracker(General Counsel)in

Co-investorsALAlta PartnersCACatalio Capital Management, LPDCDC Investment PartnersFRFrazier Life SciencesLOLongitude CapitalLOLongwood Fund+2 more

Leo Capital is a venture capital firm founded by operators with experience building and scaling category-defining companies, investing across continents with a focus on India and global markets.

AI & Machine LearningEnterprise SoftwareFintechSingapore, SG

RGRajul Garg(Founder & Managing Partner)inSVShwetank Verma(Co-founder & Managing Partner)in

Co-investorsINInterplay Ventures Early Stage Management LlcJEJetty VenturesTETesi (Finnish Industry Investment Ltd)FLFlint CapitalYUYu Galaxy

Leo Cancer Care develops upright radiotherapy and particle therapy solutions that integrate CT imaging with patient positioning systems.

Deep TechHardwareHealthtechMedical Devices

STStephen Towe(Founder)in

Co-investorsCACatalio Capital Management, LPDEDevice of Tomorrow CapitalSESerra VenturesSTStar51 CapitalYUYu GalaxyMAMana Ventures

Muse Capital is an early-stage venture capital firm that invests in consumer technology companies focused on how people care, play, and live.

AI & Machine LearningConsumerDigital Health

RSRachel SpringateinAGAssia Grazioli-Venierin

Co-investorsDADarco CapitalALAlumni VenturesGEGeneral CatalystRERethink Impact

NextPoint is a precision therapeutics company developing cancer treatments targeting the B7-H7/HHLA2 axis, including a T-cell engager, an antibody-drug conjugate with proprietary linker technology, and a multi-functional checkpoint inhibitor.

BiotechHealthtechAustin, US

GFGordon Freeman(Scientific Founder)XZXingXing Zang(Scientific Founder)inICIvan Cheung(Chief Executive Officer)inLGLeena Gandhi(Chief Medical Officer)inTNTatiana Novobrantseva(Chief Scientific Officer)inAHAxel Hoos(Director)

Co-investorsCACatalio Capital Management, LPMPMPM BioImpactSASanofi VenturesINInvusLELeaps by BayerSISixty Degree Capital

Noetik builds AI models to identify cancer patients most likely to respond to treatments and to discover new oncology drug targets.

AI & Machine LearningBiotechHealthtechSouth San Francisco, US

Jacob Rinaldi(Founder)inRonald Alfa(Executive Officer, Director, Promoter)RARon Alfa, MD, PhD(Co-Founder, CEO)inRon Alfa(Founder)Ron Alfa Jacob Rinaldi(Founder)

BoardJHJames Hardiman(Director)in

Co-investors1111.2 CapitalBRBreakout LabsBRBreakout VenturesCACatalio Capital Management, LPEPEPIC VENTURESINIntermountain Health+6 more

Octant is a therapeutics company that develops small molecule drugs to treat protein misfolding diseases.

AI & Machine LearningBiotechDeep TechMedical DevicesEmeryville, US

SKSri Kosuri(Founder)inRHRamsey Homsany(Founder)inRobert Andrade(Executive Officer, Director, Promoter)Maurice J. Costantini(Executive Officer, Director, Promoter)

Co-investorsANAndreessen Horowitz+N+ND Capital8V8VCCACarbon SiliconCACatalio Capital Management, LPEXExplorer Investments+9 more

Pheast Therapeutics develops immunotherapies targeting cancer, building on foundational research from Stanford's stem cell research institute.

BiotechHealthtechMedical DevicesRedwood City, US

IWIrv Weissman(Cofounder, Scientific Advisor, Board Director)RMRavi Majeti(Cofounder, Scientific Advisor, Board Observer)ABAmira Barkal(Principal Founder, Scientific Advisor, Board Director)inRMRoy Maute(Cofounder & Chief Executive Officer)in

BoardJVJacob Vogelstein(Director)SGSteven Gillis(Director)in

Co-investorsARARCH Venture PartnersCACatalio Capital Management, LPALAlexandria

ProSomnus offers oral appliance devices for treating obstructive sleep apnea and snoring, positioned as an alternative to CPAP machines.

Digital HealthHealthtechMedical DevicesWellness & FitnessPleasanton, US

Leonard Liptak(Executive Officer, Director)Sung Kim(Executive Officer)Jason Orchard(Director)Steven Pacelli(Director)Heather Rider(Director)Laing Rikkers(Executive Officer, Director)

Co-investorsCACatalio Capital Management, LPSPSpring Mountain Capital

Ratio Therapeutics develops radiopharmaceuticals for oncology, working on targeted radiochemistry, discovery, and preclinical and clinical development.

BiotechHealthtechMedical DevicesBoston, US

JBJohn Babich(Director, President & Chief Scientific Officer)inJHJack Hoppin(Chairman & Chief Executive Officer)inJack Hoppin, Ph.D.(Chairman, Chief Executive Officer)WCWilliam Cupelo(Chief Business Officer)MFMatthias Friebe(Chief Technology Officer)inSHScott Holbrook(Chief Commercial and Manufacturing Officer)in

Rhapsogen is developing a precision biologic therapy aimed at treating autoimmune diseases, focused on efficacy, safety, and durability.

BiotechHealthtech

Co-investorsCACatalio Capital Management, LP

HealthtechCambridge, US

RDRahul Dhanda(Executive Officer, Director)inJCJames Collins(Director)DWDavid Walt(Director)in

BoardIRIssi Rozen(Director)in

Co-investorsCACatalio Capital Management, LPILIllumina VenturesGOGood VenturesGVGV (Google Ventures)NONorthpond VenturesNONovalis LifeSciences

Somethings connects teenagers with peer mentorship support to address gaps in mental health access in the United States.

Digital HealthHealthtechMental HealthWellness & Fitness

PGPatrick Gilligan(Founder)in

Co-investorsCACatalio Capital Management, LPCOCoalition OperatorsGEGeneral CatalystMAMana VenturesTATau VenturesBEBehind Genius Ventures+4 more

Star Therapeutics develops treatments aimed at addressing real-world patient needs.

BiotechSouth San Francisco, US

ARAdam Rosenthal(Founder & CEO)inNSNancy Stagliano(Director)inMichelle Carpenter(Executive Officer)Sandip Panicker(Executive Officer)SRScott Robertson(Executive Officer)inGary Patou(Executive Officer)in

Co-investorsFRFrazier Life SciencesOROrbiMedRARA CapitalSASanofi VenturesSOSofinnova VenturesVIViking Global+11 more

Syndeio Biosciences is a synapse-focused biotech developing precision neurotherapeutics for neuropsychiatric, mental health, and cognitive disorders such as depression and Alzheimer's.

AI & Machine LearningBiotechDigital Health

Co-investorsEVEvolution VC PartnersPAPalo Santo VCTETenmile

Visby offers an FDA-authorized at-home PCR test kit for women's sexual health that detects chlamydia, gonorrhea, and trichomoniasis from a single swab, delivering private results via a mobile app in about 30 minutes with included same-day telehealth for positive results.

ConsumerDigital HealthFemTechHealthtechMedical DevicesTokyo, US

ADAdam de la Zerda(Founder)in

Co-investors+N+ND Capital181809 CapitalAMAmplify PartnersARArtiman VenturesG G Vision CapitalJ-J-Ventures+6 more

Volastra Therapeutics is a drug discovery and development company working on novel cancer therapies.

BiotechHealthtechNew York, US

SBSamuel Bakhoum(Co-Founder & Chief Scientific Officer)inLewis Cantley(Founder and Chair of Scientific Advisory Committee)Olivier Elemento(Founder and Scientific Advisor)DPDavid P. Southwell(Chief Executive Officer)in

BoardRMRobert Mittendorff(Director)inJGJill Goldstein(Director)in

Co-investorsDRDroia VenturesARARCH Venture PartnersB B Capital GroupB4B4 CapitalVIVida VenturesPOPolaris Partners