Refactor Capital — Full Portfolio

Solugen develops a biomanufacturing platform using fermentation and bioprocessing technology to produce specialty chemicals at scale.

Advanced ManufacturingBiotechCleantechClimate TechHealthtechHouston, US

SHSean Hunt(Founder/CTO)inGCGaurab Chakrabarti(Founder)in

BoardSBSeth Bannon(Director)in

Co-investorsFIFifty YearsFOFounders FundLOLowercarbon CapitalY Y CombinatorBABaillie GiffordGIGIC+40 more

64x provides a platform and product suite for manufacturing advanced therapeutics, including gene therapies, cell therapies, and biologics.

BiotechDeep TechMedical Devices

Co-investorsBOBoxGroupFIFirst Round CapitalFIFifty YearsFUFuture VenturesLILifeforce CapitalNONorthpond Ventures+1 more

64x develops infrastructure and manufacturing systems for next-generation medicines, focusing on genetic engineering, cell line development, and computational biology to enable scalability of advanced therapies.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesSan Francisco, US

LRLexi Rovner(Co-founder & CEO)in

Co-investorsFIFifty YearsFUFuture VenturesLILifeforce CapitalRARaptor GroupY Y CombinatorALAlix Ventures+8 more

Able Health provides software for physician organizations to administer value-based care programs, including quality measure calculation and health plan coordination to reduce administrative overhead.

HealthtechSan Francisco, US

RKRachel Katz(Founder/CEO)inSDSteve Daniels(Founder/President)in

Co-investorsLILifeforce CapitalSOSoma CapitalY Y CombinatorFIFifty YearsGRGreat Oaks Venture Capital

Adventris is a biotechnology company developing cancer immunotherapy treatments.

BiotechHealthtechBaltimore, US

JHJen Herbach(Founder)inWCWilliam Collis(Founder)inMYMark Yarchoan(Founder)

Co-investorsY Y CombinatorFEFelicis VenturesILIllumina VenturesKHKhosla VenturesPEPeak XV PartnersVEVenture Investment Associates

Aether develops additives that blend into engineering-grade nylons to enable faster, high-throughput fused filament (FFF/FDM) 3D printing while maintaining mechanical strength and dimensional accuracy.

Advanced ManufacturingAI & Machine LearningBiotechDeep TechHardwareNew Materials

PJPavle Jeremic(Founder & CEO)inJZJay Zaveri(Co-Founder & President)

Co-investors4D4DX VenturesABAbstract VenturesARArtis VenturesBLBlue Bear VenturesBOBoxGroupCACalm Ventures+12 more

AKASA provides generative AI solutions for healthcare revenue cycle management, helping health systems automate administrative workflows and reduce costs.

AI & Machine LearningEnterprise SoftwareHealthtech

MWMalinka Walaliyadde(CEO, Co-founder, and Board Member)inBBBen Beadle-Ryby(Chief Revenue Officer, Co-founder, and Board Member)inAAAndy Atwal(Vice President of R&D Special Projects and Co-founder)inVGVarun Ganapathi, Ph.D.(Co-founder and Advisor)

Co-investorsANAndreessen HorowitzBOBond Capital ManagementCOCoatue ManagementFOFOG VenturesFOFounders Circle CapitalOLOlive Capital+3 more

Astranis manufactures small, high-powered geosynchronous satellites equipped with advanced digital processing technology for global telecommunications and connectivity services.

Advanced ManufacturingDeep TechHardwareSpace TechSan Francisco, US

JGJohn Gedmark(Founder/CEO)inRMRyan McLinko(Founder/CTO)inMike Mancini(Executive Officer)

BoardMCMartin Casado(Director)inEBEthan Batraski(Director)inDan Berkenstock(Director)

Co-investorsANAndreessen HorowitzATATEL VenturesBLBlack FlagBOBoxGroupCACantos VenturesCHCherubic Ventures+83 more

A wearable device company developing brain-sensing technology using nanotechnology for consumer use.

Deep TechHardwareHealthtech

Co-investorsACAccelCOCompoundUNUnshackled VenturesVEVery Serious VenturesBLBlackRockLOLocalGlobe+2 more

Avail is a blockchain infrastructure project focused on scalability solutions for blockchain ecosystems.

Crypto & Web3Data & Infrastructure

AAAnurag Arjun(Co-Founder)in

Co-investorsAMAmino CapitalBOBorderless VentureCOCoatue ManagementDRDragonflyFIFigmentHTHTX Ventures (ex Huobi Ventures)+20 more

Berkeley Yeast develops genetically engineered yeast strains for the fermented beverages industry, offering improved flavor control, scalability, and consistency while reducing resource and energy consumption.

AgTechBiotechFoodTechBerkeley, US

CDCharles Denby(Founder)inPhilip Austin(Director)

Co-investorsCOCollaborative FundDYDYDX CapitalANAnterra Capital

Betty Labs built Locker Room, a live audio app for sports fans, and was acquired by Spotify in March 2021.

Co-investorsGVGV (Google Ventures)SCScript Capital

Biobot pioneers wastewater epidemiology, monitoring pathogens and substances in sewage to provide real-time public health surveillance at the community level.

BiotechData & InfrastructureGovTechHealthtechBoston, US

NGNewsha Ghaeli(Cofounder & President)inMMMariana Matus(Founder)inMariana Guadalupe Matus Garcia(Executive Officer, Director)

BoardVPVivek Pattipati(Director)inAPAndrew Perlman(Director)in

Co-investorsAMAmerican Family Insurance Institute for Corporate and Social ImpactBLBlindspot Ventures Management CoDCDCVC (Data Collective)DODorm RoomHOHomebrewPAPathbreaker Ventures+21 more

The company builds "Biological Adapters" that integrate living neurons with AI foundation models to improve performance and reduce training cost, and it operates an algorithm discovery platform based on principles from biological neural systems.

AI & Machine LearningBiotechDeep Tech

Co-investorsBABanyan VenturesPRPrimary Venture PartnersWOWonder VenturesE1E1 Ventures

BioRender is a software tool that enables scientists to create and share professional scientific illustrations and figures.

BiotechEdTechEnterprise SoftwareSaaSToronto, CA

RMRyan Marien(Founder)inKSKatya Shteyn(Founder)inSAShiz Aoki(CEO and Co-founder)in

Co-investorsY Y CombinatorFIFifty YearsFUFundersClubOLOlima VenturesSTStandard CapitalBRBraewick Holdings+5 more

Los Angeles, US

Charles Mason(Executive Officer, Director)

Co-investorsBLBlockchain CoinvestorsNINirvana CapitalPAPantera CapitalCHChapter OneRERecursive Ventures

Brave Care operates pediatric primary and urgent care clinics designed to treat common acute conditions in children, supplemented by remote consultations delivered by clinicians.

HealthtechPortland, US

AMAsa Miller(Founder)inD"Darius "Bubs" Monsef(Founder)inMTMaryam Taheri(Founder)inCFCorey Fish, MD(Founder)inGary Gerlacher(Executive Officer, Director)Corey Fish, M.D.(Executive Officer, Director)

Co-investorsALAlumni VenturesAVAV8 VenturesFIFifty YearsVEVentureSouqY Y CombinatorZIZillionize+17 more

Miist develops inhaled microparticle therapeutics that deliver medicine to the bloodstream in 30 seconds, targeting conditions like migraine, pain, and anxiety where rapid onset is critical.

BiotechDigital HealthHealthtechMedical DevicesAlameda, US

EEEric Ezerins(Cofounder, Head of Technology)inDSDalton Signor(Cofounder, CEO)inRandy Krebs(Executive Officer)JSJeffrey Schuster(Chief Technology Officer)inEvan Alfano(Director)

Co-investorsCACALIFORNIA INNOVATIONENEntrepreneur FirstFRFREEFLOWTHThe Innovation Space

Brelle develops a modular energy platform for high-performance machines, combining battery hardware, embedded AI-enabled software, and automated manufacturing.

Deep TechEnergyHardwareLos Alamitos, US

Martin Hermez(Founder)Nachiket V(Founder)

Co-investorsFIFirst Star Ventures

Bulk MRO operates a B2B supply chain and finance platform serving enterprise, government, and SME customers with industrial products, metals, agro-commodities, chemicals, and logistics services.

B2B MarketplacesEnterprise SoftwareFintechLogistics & Supply ChainSaaSNew York City, US

DSDevang Shah(Founder)inGSGaurang Shah(Founder/Director)inCharles Lorenceau(Director)

Co-investorsAAAAF Management Ltd.AFAfore CapitalFJFJ LabsRERebright PartnersSWSwitch VenturesY Y Combinator+9 more

Call9 provides emergency and palliative care to patients in skilled nursing facilities by combining onsite clinical care specialists with remote emergency medicine physicians who evaluate and treat patients via a proprietary platform, reducing response times from an average of 64 minutes to immediate care.

HealthtechNew York City, US

CTCelina Tenev(Founder)

Co-investorsFUFundersClubY Y CombinatorBIBios PartnersGRGreat Oaks Venture CapitalHIHillcrest Venture PartnersINIndex Ventures+8 more

CCG.ai develops software that uses clinical and genomic data to help oncologists select appropriate cancer treatments for individual patients, with a focus on identifying predictive biomarkers linked to treatment response.

HealthtechMedical DevicesCambridge, GB

JCJohn Cassidy(Founder/CEO)inNPNirmesh Patel(Founder/Chief Scientific Officer)inETEvaline Tsai(Founder/CPO)in

Co-investorsAMAmplify PartnersFUFundersClubPIPi CampusSOSoma CapitalY Y CombinatorAMAME Cloud Ventures+7 more

Causal Labs builds a Large Physics foundation Model to learn causality through physics and weather observations.

AI & Machine LearningDeep TechSan Francisco, US

Dar Mehta(Founder)inYue (Kelsie) Zhao(Founder)

Co-investorsBOBoxGroupKAKarman VenturesKIKindred VenturesTRTranspose Platform ManagementUNUnion Square Ventures (USV)OTOtherwise

Checkerspot uses microalgae precision fermentation to produce specialized lipids and fats, including a bio-equivalent source of the sn-2 palmitate fat found in mother's milk, rare bioactive fatty acids, and tropical fat alternatives.

BiotechClimate TechFoodTechNew MaterialsAlameda, US

Scott Franklin(Executive Officer, Director)inCDCharles Dimmler(Executive Officer, Director)inJKJohn Krzywicki(CEO)inLWLayla Ward(CFO)inCLCasey Lippmeier(CTO)inLPLeon Parker(SVP, Molecular Biology)in

Co-investorsBABaruch Future VenturesBRBreakout VenturesCACavallo VenturesBUBuilders VCKDKdT VenturesPLPlug and Play Ventures+2 more

Clover Health is a health insurance provider offering low-cost plans with minimal premiums, copays, and prescription drug costs.

Digital HealthHealthtechInsurTechJersey City, US

VGVivek Garipalli(Executive Officer, Director)inATAndrew ToyinKris Gale(Executive Officer, Director)

BoardNTNat Turner(Director)inMike Dixon(Director)JKJosh Kopelman(Director)in

Co-investorsARArena VenturesBOBoxGroupFIFirst Round CapitalFLFloodgateGVGV (Google Ventures)LILifeforce Capital+6 more

Consus provides an API that directs AI requests to secure infrastructure built for handling controlled data in aerospace and defense sectors, eliminating the need for customers to manage compliance and infrastructure separately.

Advanced ManufacturingAI & Machine LearningDeveloper ToolsSpace TechSan Francisco, US

EMEric Magliarditi(Founder)in

Co-investorsY Y Combinator46468 CapitalGEGeneral Catalyst

Culture Biosciences provides software and bioreactor hardware solutions for bioprocess development, enabling researchers to design, monitor, and analyze experiments remotely with cloud-native analytics and AI/ML insights.

AI & Machine LearningBiotechCloud ComputingHealthtechSan Francisco, US

WPWill Patrick(Founder/CEO)inMBMatt Ball(Founder/CTO)in

Co-investorsCOCompoundDCDCVC (Data Collective)GRGRIDS CapitalHEHemisphere Ventures LLCTETeam Builder VenturesTHThe E14 Fund+20 more

Curative offers an employer-sponsored health insurance plan with $0 copays, $0 deductibles, and a single monthly premium, giving members access to a nationwide provider network, telehealth, and $0 preferred prescriptions.

Digital HealthHealthtechInsurTechAustin, US

ITIsaac Turner(Founder)inFrederick Edward Turner(Executive Officer, Director)TDTami Denise Wilson-Ciranna(Chief Financial Officer)

Co-investorsDCDCVC (Data Collective)JAJam FundSOSoma CapitalUNUndeterred CapitalGAGalaxy Digital Assets Fund

Deliverr was an e-commerce fulfillment startup offering fast, Amazon Prime-like two-day delivery for merchants selling on marketplaces like Shopify, Walmart, and eBay via a distributed network of warehouses.

AI & Machine LearningEnterprise SoftwareLogistics & Supply ChainSaaSSan Francisco, US

MKMichael Krakaris(Founder)in

Co-investors8V8VCACActivant CapitalALAlumni VenturesKRKrillion VenturesNFNFI Ventures, LLC9Y9Yards Capital+29 more

Enzyme develops a Quality Management System (QMS) software platform for life science companies including drug, biologic, device, and digital product manufacturers, designed to streamline regulatory workflows and generate FDA-ready documentation.

Enterprise SoftwareHealthtechMedical DevicesSaaSSan Francisco, US

JSJared Seehafer(Founder/CEO)inJGJacob Graham(Founder/Vice President QA/RA)in

Co-investorsDCDCVC (Data Collective)SOSoma CapitalY Y CombinatorAGAg Startup Engine SeedHAHack VCINInformed Ventures Advisors, Llc+4 more

Epana Bio develops therapies for autoimmune diseases by leveraging genomics and AI to identify and target cellular origins of disease, with a focus on precision medicine for patient populations.

AI & Machine LearningBiotechDigital Health

Co-investorsBRBreakout LabsBRBreakout VenturesHAHAWKTAILHUHummingbird VenturesOMOMX VenturesKDKdT Ventures

Evernow provides virtual menopause care for women, offering one-time video visits and ongoing membership access to certified menopause providers who prescribe hormone therapy and estrogen replacement.

Digital HealthFemTechWellness & Fitness

AJAlicia Jackson(Founder)in

Co-investorsALAlumni VenturesNENew Enterprise Associates (NEA)8V8VCCOCoelius Capital

Xometry provides an instant quoting and manufacturing platform that connects startups and enterprises with a global network of manufacturers to produce precision components from prototype through high-volume production.

Advanced ManufacturingB2B MarketplacesSaaS

Co-investorsAUAugust CapitalMAMaryland TEDCOTETEDCO

Fleetzero designs and retrofits commercial vessels with battery-electric propulsion systems to decarbonize ocean shipping.

Advanced ManufacturingCleantechClimate TechEnergyHardwareRoboticsHouston, US

SHSteven Henderson(Founder)inMCMike Carter(Founder)inSteven H(Founder)

Co-investorsOBObvious VenturesBRBreakthrough Energy VenturesCACantos VenturesDADarco CapitalMAMaersk GrowthPIPioneer+9 more

Floodbase offers a parametric insurance platform that uses flood data and near real-time flood event monitoring to help insurers design, price, underwrite, and trigger flood coverage.

AI & Machine LearningClimate TechData & InfrastructureInsurTechBrooklyn, US

BSBessie Schwarz(Co-founder)inBTBeth Tellman(Co-founder)in

BoardMarty Schneider(Director)SBSasha Brown(Director)JLJohn Loser(Director)in

Co-investorsBUBURNT ISLAND VENTURESCOCollaborative FundECEcosystem Integrity FundFLFloating PointGRGroundForce CapitalLOLowercarbon Capital+3 more

From Yellow To Orange (fyto) is a Japanese company that produces and distributes music and video, composes and arranges music, and plans, develops, and sells games and digital content.

ConsumerGamingMedia & EntertainmentPetaluma, US

KEKenji Eno(Founder)YIYuka Iino(Representative Director (CEO))Jason Prapas(Executive Officer, Director)Harold Kruth(Director)Andy Wheeler(Director)

Co-investorsAGAgFunderGVGV (Google Ventures)FIFirst Star Ventures

Fyto develops nutrient recycling and protein production technology for farmers, enabling sustainable food production with reduced environmental impact.

AgTechClimate TechFoodTechRoboticsSan Francisco Bay Area, US

Jason Prapas(Founder)

Co-investorsCICity LightAGAgFunderBABaukunstFIFirst Star VenturesGVGV (Google Ventures)

Gencove provides direct-to-consumer genetic sequencing and polygenic risk scoring for health insights.

BiotechDigital HealthHealthtechNew York, US

Tomaz Berisa(Executive Officer, Director)inJPJoseph Pickrell(Executive Officer, Director)in

BoardSESara Eshelman(Director)in

Co-investorsBRBread And Butter Ventures, LlcSPSpero VenturesVEVersion One VenturesALAlexandriaBABalaji SrinivasanBUBurst Capital+1 more

General Galactic is a space infrastructure company focused on building orbital and extraterrestrial infrastructure, drawing inspiration from science fiction concepts like propellant generation for off-Earth settlement.

Deep TechHardwareLogistics & Supply ChainSpace TechEl Segundo, US

HMHalen Mattison(Cofounder)inLNLuke Neise(Cofounder)in

Co-investorsANAntiBOBoxGroupHAHarpoon VenturesINIndustrious VenturesPAPathbreaker VenturesSESeraphim Space+1 more

Granza Bio develops immunotherapy treatments leveraging naturally-occurring attack particles that are released from cytotoxic immune cells to target diseases including cancers, autoimmunity, and infections.

BiotechDeep TechDigital HealthHealthtechSan Francisco, US

Prof. Dustin(Co-founder)ANAshwin Nandakumar(Founder)inAJAshwin Jainarayanan(Founder)inAMAshwin Menon Nandakumar(Founder)in

Co-investorsFEFelicis VenturesMEMetaplanetOXOxonian VenturesPIPioneerRIRitual CapitalY Y Combinator+4 more

Headspace is a mental health app that delivers personalized support through meditation, mindfulness, AI-powered guidance, coaching, therapy, and psychiatry services for individuals and organizations worldwide.

Digital HealthHealthtechMental HealthWellness & FitnessSanta Monica, US

Andy(Co-founder)Richard Marsh Pierson(Executive Officer, Director)Andrew David Puddicombe(Executive Officer, Director)SBSean Brecker(Executive Officer)inTPTom Pickett(Chief Executive Officer)in

BoardScott Kriens(Director)

Co-investors141435 CapitalADAdvance Venture PartnersADAdvancit CapitalBEBessemer Venture PartnersBRBreyer CapitalCICity Light+17 more

A revenue intelligence platform that provides deal context, risk visibility, and marketing attribution to help sales and revenue teams win more deals.

AI & Machine LearningMarketing TechSaaSSales Tech

Co-investorsZIZillionize

Hexium develops Atomic Vapor Laser Isotope Separation (AVLIS) technology that uses lasers and electric fields to enrich isotopes, starting with lithium.

Deep TechEnergyNew MaterialsAustin, US

Leonard Charles Jarrott(Executive Officer, Director)Jacob Peterson(Executive Officer, Director)in

BoardMPMike Palank(Director)in

Co-investorsHUHumba VenturesJUJulian CapitalMAMaC Venture CapitalOVOverture ClimateR7R7 Partners

Vitra Bio is a biotechnology company developing technology aimed at transforming fertility treatment.

BiotechFemTechHealthtech

Ivana Muncie-Vasic(Chief Executive Officer and Founder)inJLJohn Langowski(Chief Technology Officer)in

Co-investorsBRBreakout VenturesFOForeground CapitalNONorth South VenturesSPSpacecadet VenturesBOBoom Capital Ventures

Kin Euphorics makes non-alcoholic functional beverages formulated with adaptogens, nootropics, and botanics intended to affect mood, brain function, and immunity.

ConsumerDirect to ConsumerWellness & Fitness

JBJen Batchelor(Founder)in

Co-investorsBOBoxGroupCACanaan PartnersCOCollaborative FundFIFifty YearsMEMelitas Ventures LlcTRTrousdale Ventures+2 more

Kip Health operates a therapy service that pairs in-person therapist sessions with a private mobile app for asynchronous communication between visits, using measurement-based clinical protocols.

HealthtechSan Francisco, US

TZTi Zhao(Founder)in

Co-investorsY Y CombinatorGRGreat Oaks Venture CapitalSLSlow Ventures

Knowde provides a data management platform for industrial businesses, specifically chemicals and ingredients, that uses AI to extract, structure, and harmonize fragmented master data from legacy systems.

B2B MarketplacesData & InfrastructureEnterprise Software

AAAli Amin-Javaheri(CEO)inWKWojciech Krupa(Founder)in

Co-investorsALAlumni VenturesBEBee PartnersCOCoatue ManagementFJFJ LabsG G SquaredMAMantis Capital+6 more

Legalist is an institutional alternative asset management firm that invests in legal assets, including litigation finance, government receivables, and distressed debt instruments, combining proprietary technology with legal underwriting to generate risk-adjusted returns for institutional clients.

AI & Machine LearningFintechSan Francisco, US

CHChristian Haigh(Founder)inESEva Shang(Founder)in

Co-investorsY Y CombinatorAGAgrolimen VenturesRORough Draft VenturesVYVy Capital

Loyal develops longevity drugs for dogs, targeting the biological processes of aging to extend healthy lifespan and reduce age-associated disease.

BiotechHealthtechLongevity

CHCeline Halioua(Founder & CEO)in

Co-investorsAGage1BABain Capital VenturesBOBoxGroupCOCollaborative FundFIFirst Round CapitalFLFlucas Ventures+13 more

LTSE Private Markets is a platform operated by the Long-Term Stock Exchange that connects institutional and accredited investors to late-stage private companies through direct and secondary market transactions.

Enterprise SoftwareFintechSan Francisco, US

EREric Ries(Founder/CEO)inJBJohn Bautista(Founder)inNRNatalie Risoin

BoardBSBrian Singerman(Director)in

Co-investors50500 GlobalALAlumni VenturesANAndreessen HorowitzCOCollaborative FundFLFloodgateINInitialized Capital+13 more

Lucy manufactures tobacco-free nicotine pouches in various flavors and strengths designed for consumer use.

BiotechConsumerE-commerceFoodTechLos Angeles, US

JCJohn Coogan(Founder)inSHSamy Hamdouche(Founder)inDRDavid Renteln(Founder)in

Co-investorsGRGreycroftRRRRE VenturesY Y CombinatorBOBoxGroupGRGreycroft PartnersMBMBX Capital+3 more

Lumindt builds its own commercial battery energy storage systems that capture surplus solar or low-cost grid energy for later use, helping commercial operations reduce operating costs and avoid peak utility rates.

CleantechEnergyHardwareSan Francisco, US

Bruno Geoly(Co-Founder)Mia Rath(Co-Founder)

Co-investorsINInvariantes FundMIMission One Capital

Macro Oceans develops seaweed-based (kelp) feedstocks and materials as a low-carbon alternative to petroleum-based chemicals and products, building a traceable seaweed supply chain with brand, technology, and grower partners.

Advanced ManufacturingBiotechCleantechClimate TechFoodTechNew MaterialsSan Francisco, US

MPMatthew Perkins(Founder)in

Co-investorsHAHAWKTAILLOLowercarbon CapitalKNKnollwood Investment AdvisoryMCMcKinley Alaska Private InvestmentSCSchox Venture Capital

The page presents "The Pokies Net," an online casino targeting Australian players with a catalog of over 1,600 pokies, table games, and live dealer titles from providers like NetEnt, Pragmatic Play, and Evolution Gaming.

ConsumerGaming

Co-investorsHAHAWKTAILNANat TurnerALAlexandria

Modern Health provides mental health support solutions for employers with over 100 employees.

Digital HealthEnterprise SoftwareHealthtechHR TechMental HealthSan Francisco, US

AWAlyson Watson(Founder/CEO)inEJErica Johnson(Director)AFAlyson Friedensohn(Executive Officer, Director)inA(Alyson (Friedensohn) Watson(Founder)in

Co-investors0101 AdvisorsAFAfore CapitalBABattery VenturesKLKleiner PerkinsMEMerus CapitalMGMGV.VC+8 more

Modulo is a biotech company focused on the neuroimmune system, developing treatments for brain and central nervous system disorders.

AI & Machine LearningBiotechDeep TechLos Altos, US

Mike Horowitz(CEO & Co-founder)JIJustin Ichida(Co-founder)inScott Patterson(CTO & Co-founder)inJoe Wagner(Chief Development Officer)

BoardALAlda Leu Dennis(Director)inNicholas Saccomano(Director)

Co-investorsCACantos VenturesHAHAWKTAILINInitialized CapitalSPSpacecadet VenturesBIBiovergeBUBuilders VC

Mythic Therapeutics was a clinical-stage biotech developing next-generation antibody-drug conjugates for cancer using its proprietary FateControl technology.

BiotechWaltham, US

BFBrian Fiske(Executive Officer, Director)GEGeorge Eliades(Executive Officer, Director)inSPSandra Poole(Executive Officer)inAlex Nichols(Executive Officer, Director, Promoter)

BoardBRBryan Roberts(Director)inPeter Hecht(Director)

Co-investorsFOForesite CapitalHEHemi Ventures, LlcLILifeforce CapitalNANat TurnerVEVenrock Associates

NetworkOcean builds underwater and floating data center systems cooled by seawater, reducing power consumption by up to 40% and eliminating freshwater usage compared to traditional facilities.

Advanced ManufacturingAI & Machine LearningCleantechClimate TechCloud ComputingHardwareSan Francisco, US

SMSam Mendel(CEO, Co-Founder)inEKEric Kim(CTO, Co-Founder)in

Co-investorsPIPioneerSOSoma CapitalTRTranspose Platform ManagementY Y Combinator

Octant is a therapeutics company that develops small molecule drugs to treat protein misfolding diseases.

AI & Machine LearningBiotechDeep TechMedical DevicesEmeryville, US

SKSri Kosuri(Co-founder)inRHRamsey Homsany(Founder)inRobert Andrade(Executive Officer, Director, Promoter)Maurice J. Costantini(Executive Officer, Director, Promoter)

Co-investorsANAndreessen Horowitz+N+ND Capital8V8VCCACarbon SiliconCACatalio Capital Management, LPEXExplorer Investments+9 more

Ophelia provides medication-assisted treatment for opioid addiction through a telemedicine platform, allowing patients to receive care without attending residential rehab.

Digital HealthHealthtechWellness & FitnessNew York City, US

MGMattan Griffel(Founder)inZGZack Gray(Founder)inDADr. Arthur Robin Williams(Codesigner)

BoardGYGreg Yap(Director)inDADr. Adam Bisaga(Codesigner)

Co-investorsMEMenlo VenturesY Y CombinatorFOFour Acres CapitalGEGeneral CatalystGOGood Friends64640 Oxford+6 more

Orchid provides an electronic health record system with AI capabilities for solo and small-group mental health practices, handling administrative tasks and clinical documentation to reduce manual work.

AI & Machine LearningHealthtechSaaSSan Francisco, US

JPJoseph Pomianowski(Founder)in

Co-investorsY Y CombinatorDADay One Ventures

Orchid is a personal assistant that operates via text messaging to help users with organization, information retrieval, and task completion.

AI & Machine LearningConsumerEnterprise SoftwareFuture of WorkSan Francisco, US

NANizar Abi Zaher(Founder)inAWAdam Wazzan(Founder)in

Co-investorsHAHartmann CapitalPIPioneerY Y Combinator191984 Ventures Management, LlcDADay One VenturesKLKleiner Perkins

Orchid Hospital operates two healthcare facilities in Phnom Penh, Cambodia, providing specialized obstetrics, gynecology, pediatrics, maternity care, and general medical services.

HealthtechMedical DevicesPhnom Penh, KH

Co-investorsNANavis Capital PartnersPEPebblebedDADay One VenturesINIntel CapitalTETeam8

Orchid offers whole genome sequencing-based genetic screening of embryos during IVF as well as preconception testing for couples, analyzing DNA to identify predispositions to monogenic diseases, chromosomal abnormalities, and polygenic risks.

BiotechDigital HealthFemTechSan Francisco, US

Alexandra Meyer(President and Chief Executive Officer of Issuer)

BoardEmily Anhalt(Director of Issuer)

Co-investorsBABalaji SrinivasanBLBlockchain CoinvestorsCACarnrite VenturesHAHartmann CapitalPEPebblebedFRFred Ehrsam

Parallel Bio develops human immune organoids and computational tools to predict drug efficacy across diverse patient populations, replacing animal testing in drug discovery.

AI & Machine LearningBiotechDeep TechHealthtechSan Francisco, US

RDRobert DiFazio(Founder)inJHJuliana Hilliard(Founder)in

Co-investorsAIAIX VenturesBRBreakout VenturesHUHumba VenturesIMImmeasurableJUJulian CapitalMEMetaplanet+18 more

AI-powered pathology for improved patient outcomes

Boston, US

ABANDREW BECK(Executive Officer, Director)inAKADITYA KHOSLA(Executive Officer, Director)

BoardMICHELLE DIPP(Director)SLSTANLEY LAPIDUS(Director)inJEFF LEIDEN(Director)

Co-investors8V8VCBIBIOSPRING PARTNERSFAFairhaven Capital PartnersGEGeneral CatalystMEMerck Global Health Innovation FundMSMSD Global Health Innovation Fund+4 more

Phytoform Labs develops GM-free genome editing tools and trait engineering technologies for crop improvement, with a focus on potato and tomato varieties.

AgTechAI & Machine LearningBiotechHarpenden, GB

WPWilliam Pelton(Executive Officer, Director)inNKNicholas Kral(Director)Dhiraj Singh(Director)

Co-investorsBABackedENEniac VenturesFIFine Structures VenturesFTFTW VenturesMAManta Ray VenturesWIWireframe Ventures+1 more

PicnicHealth aggregates medical records from multiple sources and provides patients with centralized access to their health data along with AI-powered tools to understand and manage their medical information and chronic conditions.

AI & Machine LearningDigital HealthHealthtech

NLNoga Leviner(Co-founder)in

Co-investorsAMAmplify PartnersB B Capital GroupB4B4 CapitalFEFelicis VenturesGRGreat Oaks Venture CapitalJAJAZZ Venture Partners+3 more

PicnicAI develops AI technology to support patient-centered clinical care and medical research.

AI & Machine LearningDigital HealthHealthtechSan Francisco, US

NLNoga Leviner(Founder/CEO)inTATroy Astorino(Founder/CTO)inLFLuna Federici(Chief Executive Officer)in

Co-investorsY Y CombinatorAMAmplify PartnersB B Capital GroupFEFelicis VenturesFOForesite CapitalGRGreat Oaks Venture Capital+6 more

Pila manufactures home battery systems with mesh-networking capabilities for backup power and energy storage, enabling homeowners to store and manage solar and grid electricity while monitoring appliance usage through an app-based platform.

CleantechClimate TechEnergyHardwareIoT

Co-investorsALAlumni VenturesCICity LightHUHustle FundJEJetstreamXSXSLA VenturesGSGS Futures+2 more

Pit.AI develops AI systems that automatically discover and execute trading strategies for investment management by analyzing market data to identify inefficiencies, rather than relying on human forecasting models or portfolio optimization assumptions.

AI & Machine LearningFintechSan Francisco, US

YKYves-Laurent Kom Samo(Founder)in

Co-investorsY Y CombinatorCTCTC VenturesENEntrepreneur FirstVYVy CapitalZIZillionize

An AI-powered design platform that enables users to create custom stickers, merchandise, posters, and other products by describing their ideas, which the AI then generates with professional typography and layouts.

AI & Machine LearningConsumerCreator EconomySan Francisco, US

SDSuhail Doshi(Founder & CEO)in

Co-investorsCACaffeinated CapitalSHShrug CapitalY Y Combinator8V8VCDADay One VenturesGLGlobal Founders Capital+7 more

Software platform to improve drug discovery

AI & Machine LearningBiotechDeep TechNew York, US

David William Rooklin(Executive Officer, Director)Haotian Li(Director)

Co-investorsCOCollaborative FundHAHAWKTAILNONotation CapitalACAcequia Capital (AceCap)PRPreface VenturesTHThird Kind Venture Capital+1 more

Remedy Scientific decontaminates and restores environmentally compromised land using automated hardware systems combined with advanced chemistry and AI, and uses sensors to assess pollutants and tailor remediation solutions.

CleantechClimate TechRobotics

Co-investorsBOBoxGroupFLFloating PointCACantos VenturesECEclipse Ventures

Rubedo Life Sciences develops therapeutics targeting aging by eliminating senescent cells to extend human healthspan.

AI & Machine LearningBiotechLongevityMedical Devices

Co-investorsALAlumni VenturesBEBeiersdorf Innovation FundCDCDP Venture CapitalEVEvolution VenturesIKIKJ CapitalKHKhosla Ventures+4 more

Shield Bio develops nanopore sequencing technology for clinical use, designed to run rapid genetic tests in healthcare settings.

HealthtechMedical DevicesSan Francisco, US

FTFred Turner(Founder/CEO)in

Co-investorsY Y CombinatorANAndreessen HorowitzCICivilization Ventures Management, LlcESEsas VenturesFRFrialeINIntuition Capital+6 more

Smile2Impress provides invisible orthodontic treatments using clear aligner technology for patients seeking to straighten their teeth.

HealthtechMedical Devices

Co-investorsCHChannel 4 VenturesFJFJ LabsRERedbus VenturesCACAP HORN VCTRTrousdale Ventures

Spora discovers and cultivates wild fungal strains from pristine ecosystems, processing them with proprietary biotechnology and nanotechnology to create mycelium-based products.

BiotechCircular EconomyDeep TechNew Materials

Co-investorsACAceleraLatamCACapria VenturesSUSunna VenturesHEHeadwater VenturesHUHuman VenturesM1M13+2 more

The Biological Computing Co. uses living neurons to study how biological systems process information and applies those insights to improve AI model training and inference.

AI & Machine LearningBiotechDeep TechHardwareBurlingame, US

Jared Birchall(Executive Officer, Director)Steve Davis(Executive Officer)

BoardBaris Akis(Director)Antonio Gracias(Director)John Hering(Director)

Co-investors8V8VCCRCraft VenturesFOFounders FundPRPrimary VenturesSESequoia CapitalVAValor Equity Partners+1 more

Developer platform to go from code to production in minutes.

Co-investorsABAbstract VenturesALAlumni VenturesMAMaveron

Thalolabs provides two connected products for HVAC companies: a diagnostic tool that automates installation commissioning workflows, and a monitoring device that tracks system health and performance over time.

Advanced ManufacturingAI & Machine LearningClimate TechEnterprise SoftwareHardwareIoT

DBDr. Brendan Hermalyn(Founder and CEO)

Co-investorsCOCollaborative FundGIGigascale CapitalVEVery Serious VenturesVIVirta VenturesSUSuffolk TechnologiesTHThird Sphere

Trace Genomics, now part of Miraterra, provides soil analysis and genomic sequencing to give growers and agronomists insights on nutrients and pathogens across more than 70 crops and 225+ pathogens.

AgTechAI & Machine LearningBiotechBurlingame, US

Poornima Parameswaran(Executive Officer, Director)Diane Wu(Executive Officer, Director)Michael Toelle(Director)Joe Pianelli(Director)William Buckner(Director)

Co-investorsATATEL VenturesBEBeast VenturesOSOspraie Ag ScienceS2S2G InvestmentsWPWP Global PartnersFAFall Line Capital+1 more

Verge Labs builds AI models trained on multimodal human patient data to predict drug targets and patient populations for clinical development, primarily in neuroscience and central nervous system (CNS) disease.

AI & Machine LearningBiotechDeep TechDigital HealthHealthtechSan Francisco, US

AZAlice Zhang(Co-founder & CEO)inJason Chen(Cofounder)inEREmily Ripka(Head of Product & Engineering)in

Co-investorsAGAgent CapitalBOBOLD LongevityDRDraper AssociatesFIFitz Gate VenturesGRGreat Oaks Venture CapitalKAKarlin Ventures+25 more

Versa provides a receipt capture and reconciliation platform for corporate travel and expense management.

Enterprise SoftwareFintechSaaSNew York City, US

TPTed Power(Founder)inTMThomas Moore(Founder)in

Co-investorsCOCollaborative FundS3S3 VenturesSOSoma CapitalY Y CombinatorANAndreessen HorowitzCHCharacter+4 more

Vital provides an AI-driven patient experience product for hospital emergency departments that uses real-time EHR data to predict wait times, explain lab results and notes in plain language, and turn discharge instructions into a checklist accessed via a password-less text link.

AI & Machine LearningDigital HealthHealthtechSaaS

Co-investorsNANat TurnerTHThreshold Ventures

Weights & Biases is an AI developer platform that enables teams to build, train, and monitor AI agents, applications, and models with tools for experiment tracking, model management, and agent evaluation.

AI & Machine LearningData & InfrastructureDeveloper ToolsSan Francisco, US

Shawn Lewis(Executive Officer, Director)inLukas Biewald(Executive Officer, Director)inCVChris Van Pelt(Executive Officer, Director)inMariah Nagy(Executive Officer)inYEYan-David Erlich(Executive Officer)inCKCameron Kinloch(Executive Officer)in

Co-investorsAIAIX VenturesBOBond Capital ManagementBRBrighter CapitalBRBrilliant Phoenix CapitalCOCoatue ManagementDIDiagram Capital+39 more

YourChoice Therapeutics is developing YCT-529, a non-hormonal oral contraceptive for men currently in Phase 2 clinical trials.

BiotechFemTechHealthtech

ABAkash Bakshi, MSc(Co-founder & CEO)Nadja Mannowetz, PhD(Co-founder & CSO)

Co-investorsBLBlue Bear VenturesCICivilization Ventures Management, LlcFOForeground CapitalFUFuture VenturesNONorth South VenturesPOPortfolia+1 more

YourChoice Therapeutics develops YCT-529, a non-hormonal oral contraceptive for men currently in Phase 2 clinical trials that works by blocking a receptor essential for sperm production.

BiotechHealthtechMedical DevicesSan Francisco, US

ABAkash Bakshi(Founder)inNMNadja Mannowetz(Founder)in

Co-investorsBLBlue Bear VenturesFOForeground CapitalOLOlive Tree CapitalPOPortfoliaY Y Combinator8V8VC+9 more