Shepherd Ventures
Venture capitalSan Diego · Series A–Late Stage · 6 people tracked
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Investment thesis
Shepherd Ventures focuses its investment activity primarily on the San Diego region within Southern California's Tech Coast, an area it views as rich in information technology and life science industries yet underserved by venture capital relative to its market potential. The firm believes its local presence, plus the collective operating experience and personal networks of its team of managing directors, venture partners and advisors, gives it a competitive edge in this geography. It adds value through hands-on 'shepherding,' offering extensive operating expertise, advisory connections and strategic partnerships to help its portfolio companies succeed.
Source: firm website, verified Aug 3, 2026.
Team · 6 people
from the firm's website & public directoriesWhat they invest in
from 7 of 20 portfolio companiesHardware ×4Biotech ×2Deep Tech ×2Defense Tech ×2Digital Health ×2Advanced Manufacturing ×1Construction Tech ×1Consumer ×1
HQs:United States×6
Investments · 20 tracked
founders shown can be your intro pathBy year:2023 · 12021 · 12014 · 13 dated
DiaMedica Therapeutics develops therapies aimed at reducing ischemia in patients with serious vascular diseases, with an initial focus on preeclampsia, fetal growth restriction, and acute ischemic stroke.
BiotechDigital HealthMinneapolis, US
David J. Wambeke(Executive Officer)inLorianne Masuoka(Executive Officer)inRick Pauls(Executive Officer, Director)inScott Kellen(Executive Officer)inTodd Verdoorn(Executive Officer)inJulie Krop(Chief Medical Officer)in
Board seatRichard P. Kuntz· per SEC Form D · $37.5M raise · filed Jun 2023
Co-investorsCentreStone Ventures
AmplifiDx develops point-of-care molecular diagnostic tests and its DX 100 platform for family, women's, and sexual health, targeting infectious disease detection for healthcare professionals and patients.
BiotechDigital HealthFemTechHealthtechMedical DevicesPleasanton, US
Nancy Schoenbrunner(Chief Executive Officer)inShoulian Dong(Chief Scientific Officer)Daniel Schoener(Chief Product Officer)Chris Meda(Chief Commercial Officer)inMing Tan(Director)Sammy Datwani(Director)
Co-investorsAvestria VenturesBeacon AngelsSocial Starts
Lucix designs and manufactures RF electronic modules and assemblies for satellite payloads, airborne systems, and ground stations across commercial, civil, and defense applications.
Defense TechHardwareSpace TechCamarillo, US
Nick Ashwin(Founder)in
Co-investorsPalisades Growth CapitalPartners for GrowthSaints Capital
NP Photonics designs and manufactures fiber-based photonics products, including narrow-linewidth single-frequency fiber lasers, high-power fiber lasers, multi-channel laser systems, fiber amplifiers, injection seeders, mid-infrared fiber sources, and ASE sources.
Advanced ManufacturingDeep TechDefense TechHardwareNew MaterialsTucson, US
Co-investorsResearch Corporation Technologies
Quickoffice made mobile productivity software—word processor, spreadsheet, and presentation apps—for viewing and editing Microsoft Office files on smartphones and tablets.
Co-investorsMayfield FundWestern Technology InvestmentAdvantage Capital PartnersBenhamou Global Ventures
Sendio provides email security solutions designed to protect business communications, with focus on inbox security, operational efficiency, and business continuity for enterprise customers.
CybersecurityEnterprise SoftwareSaaS
Erik Nathan(President and CEO)
Co-investorsVicente Capital PartnersAthenian Venture Partners
VELUX manufactures skylight systems that open and close to provide daylight and fresh air ventilation for residential homes.
Construction TechConsumerHardware
WiSpry is a fabless RF semiconductor company that develops RF-MEMS (micro-electro-mechanical systems) devices integrated with RF-CMOS processes for mobile handset and network applications.
Deep TechHardwareIoTSemiconductorsIrvine, US
JEFFREY HILBERT(Executive Officer)RUSSELL JOHNSEN(Executive Officer)
BoardEDMUND HEALY(Director)PAUL CONLEY(Director)JEFFREY SAMBERG(Director)K.P. WILSKA(Director)
Co-investorsCedar Mundi VenturesIn-Q-Tel
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
AndigilogCeyxDigitalorchidErespLtilampsMedmanagesystemsOculirPlanet AteRevanceSiliconsystemsSpecificmediaTritech
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 2
1 IPOs · 1 acquisitions · showing 1DiaMedica TherapeuticsNASDAQ: DMAC
Frequently asked questions
- How many investments has Shepherd Ventures made?
- Shepherd Ventures has 20 tracked investments, 2 of which have exited.
- What stage does Shepherd Ventures invest at?
- Shepherd Ventures invests at the Series A, Series B, Growth, Late Stage stages.
- What is Shepherd Ventures's typical check size?
- Shepherd Ventures typically writes checks of $750K – $3M.
- What sectors does Shepherd Ventures focus on?
- Shepherd Ventures focuses on Biotech, Data & Infrastructure, Deep Tech, Enterprise Software, Hardware, Healthtech, Media & Entertainment, Medical Devices, SaaS.
- Where is Shepherd Ventures located?
- Shepherd Ventures is headquartered in San Diego, US.
- Does Shepherd Ventures lead rounds?
- Yes, Shepherd Ventures leads investment rounds.
- Who does Shepherd Ventures co-invest with?
- Shepherd Ventures most often shares deals with In-Q-Tel, Mayfield Fund, Partners for Growth, among 9 tracked co-investors.
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