Calculus Capital Ltd.
Venture capitalLondon · Seed–Late Stage · 31 people tracked
Also known as Mcdonald Glencross Limited · Mcdonald-Glencross Limited
Find your way into Calculus Capital Ltd.
1,659 people in our graph share verified history with the Calculus Capital Ltd. team — schools, employers, funds. One of them is your warm intro.
Investment thesis
Calculus is a long-standing UK manager focused on tax-advantaged investing through EIS funds and VCTs, backing EIS and VCT qualifying companies since launching the first UK approved EIS fund in 1999. It runs a generalist EIS fund annually and multiple VCT share issues, and in 2022 launched a Knowledge Intensive EIS Fund. Its approach emphasises capital appreciation, a diligent investment and monitoring process, and a track record of profitable exits. In January 2026 it added the Calculus Inheritance Tax Solution, providing secured loans for film and TV productions.
Source: firm website, verified Aug 3, 2026.
Team · 31 people
from the firm's website & curated & public directoriesWhat they invest in
from 15 of 41 portfolio companiesBiotech ×9Deep Tech ×7AI & Machine Learning ×6Healthtech ×6Medical Devices ×4SaaS ×4Fintech ×2HR Tech ×2
HQs:United Kingdom×6United States×1
Investments · 41 tracked
founders shown can be your intro pathBy year:2026 · 12025 · 12024 · 12022 · 22021 · 12018 · 17 dated
Laverock Tx is a biotechnology company working in the gene therapy and gene editing space, with a leadership and advisory team drawn from cell and gene therapy, immunology, and life-science investing backgrounds.
BiotechDeep TechHealthtech
Co-investorsEos AdvisoryFuture Planet CapitalTekfen VenturesUK Innovation & Science Seed Fund
Arctic Shores provides psychometric testing and recruitment tools designed to reduce hiring bias and support diversity goals for businesses.
AI & Machine LearningHR TechSaaS
Co-investorsBeringeaBeringea ProVen VCT
AreCor develops proprietary pharmaceutical products for diabetes, obesity, and cardiometabolic diseases using its Arestat technology platform.
BiotechDeep TechHealthtech
Sarah Howellin
Co-investorsAlbionVCSeneca Partners
Blu Wireless develops millimeter wave radio networking technology for wireless communications.
Deep TechDefense TechHardwareSemiconductorsBristol, GB
Anthony Murray(Chief Executive Officer)inJohnny Bray(Chief Financial Officer)inDave Purle(Chief Operating Officer)Ciara Barron(Director of Marketing)inDarren McNamara(Director of Technology Development)inJonathan Rogers(Director of Systems and Platforms)in
Co-investorsMaven Capital PartnersCambridge Angels groupSalica InvestmentsARMWren Capital
Bristol-based developer of mmWave wireless communication systems for defence, high-speed rail and other mobility markets.
Co-investorsGuinness VenturesPerscitus LLPWren Capital
EnsiliTech develops ensilication technology, a silica-based method to stabilise vaccines and biopharmaceuticals so they can be stored and transported without refrigeration.
BiotechCleantechDeep TechHealthtechMedical Devices
Asel Sartbaeva(Co-Founder & CEO)inMatt Slade(Co-Founder & Chief of Staff)inStephen Wells(Co-Founder & Advisor)Aswin Doekhie(Co-Founder & CTO)inSabine Ficek(CFO)inSimon Bennett(Chief Commercial Officer)
Co-investorsElbow Beach CapitalEos Advisory
Essentia Analytics provides behavioral analytics software and performance consulting for professional investors, helping fund managers reduce bias, maintain investment discipline and improve returns.
AI & Machine LearningFintechSaaS
Clare Flynn Levy(CEO)in
Co-investorsSalica Investments
Invizius develops therapeutics targeting the complement system to treat kidney disease and other disorders driven by uncontrolled immune activation.
BiotechDeep TechHealthtechMedical DevicesGlasgow, GB
Dr Magnus Nicolsonin
Co-investorsCalculusMercia VenturesOld College CapitalScottish Enterprise
Maven Screen Media is an independent production company that develops and produces multi-platform film and television content with a focus on increasing representation for women in front of and behind the camera.
Creator EconomyMedia & Entertainment
Celine RattrayTrudie Stylerin
Co-investorsAdeline
Optalitix provides an enterprise platform that consolidates pricing and underwriting workflows, enabling organizations to modernize their pricing models without disruption through incremental cloud migration and governance.
AI & Machine LearningCloud ComputingEnterprise SoftwareFintechInsurTechSaaSLondon, GB
Co-investors24 Haymarket
Oxford BioTherapeutics is a clinical-stage oncology company developing antibody-based therapies for cancer treatment.
BiotechHealthtechMedical DevicesOxford, GB
Co-investorsOxfordPercipient CapitalPerscitus LLP
Resurrect Bio develops genetic disease-resistance traits for crops by restoring plant R-genes, using its FloraFold AI platform and rapid in-planta screening for trait discovery.
AgTechAI & Machine LearningBiotech
Cian Duggan(CEO / Co-Founder)inTolga Bozkurt(Co-Founder)inSophien Kamoun(Co-Founder)
Co-investorsFuture Planet CapitalSynBioVenUK Innovation & Science Seed FundAgFunderPymwymic
Rotageek provides workforce management and scheduling software for rota planning, including demand forecasting, labour modelling, auto-scheduling, time and attendance tracking, and leave management.
AI & Machine LearningFuture of WorkHR TechRetail TechSaaS
Chris McCullough(Co-founder)inRoy Pounder(Co-founder)inNick Mann(Co-founder)in
Co-investorsVenture FoundersVolution VenturesCalculusGresham HouseGresham House VenturesMobeus Equity Partners
An end-to-end mortgage and protection platform that automates the mortgage process and integrates brokers, estate agents, homebuyers and lenders.
Conor Murphy(Founder)in
Co-investorsPembroke VCTLegal & General
AI medical diagnostics company whose DeepView imaging platform predicts whether burns and other wounds will heal.
BiotechDallas, US
J. Michael DiMaio(Executive Officer, Director)John H, Stevens(Director)Erich Spangenberg(Director)
Tagomics develops multimodal technologies for precision medicine and next-generation diagnostics.
AI & Machine LearningBiotechDeep TechMedical DevicesCambridge, GB
Dr Jack Kennefick(Co-founder, Director & Chief Executive Officer)Dr Robert Neely(Co-founder, Director & Chief Scientific Officer)
Co-investorsIllumina VenturesIQ CapitalCalculusMEIF Proof-of-Concept & Early Stage FundMercia VenturesOMX Ventures+1 more
Trogenix develops precision gene therapies for cancer using its Odysseus platform and Synthetic Super-Enhancer (SSE) technology, engineered DNA elements activated only in diseased cell states to selectively target and kill tumour cells while activating the immune system.
BiotechDeep TechHealthtech
Co-investorsAIN VenturesIQ Capital4BIO CapitalLongeVC
Wazoku is a London-based innovation management company combining an AI platform with the Innocentive open-innovation solver marketplace.
Simon Hill(Founder)inRosemarie Diegnan(Founder)in
Co-investorsCambridge Angels groupOctopus VenturesSaaS Capital
Supplies machines and supplies that kill weeds without using herbicides.
Co-investorsBoundary Capital
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Axol Bioscience Censo BiotechnologiesBooked ItBrouhaha EntertainmentC4X DiscoveryEconsultFiscal TechnologiesGratefulHinterviewHome Team ContentIpvLaverock TherapeuticsMip DiagnosticsMoNotifyOpen Energy MarketQuaiRaindog FilmsRiff RaffScancellWonderhoodWorkl
Portfolio news
latest coverage across their companies
Arecor · clinicaltrialvanguard.com · Aug 16, 2026

Smartr365 · theintermediary.co.uk · Aug 4, 2026
Resurrect Bio · eu-startups.com · May 14, 2026
Essentia Analytics · essentia-analytics.com · Oct 6, 2025
Tagomics · news-medical.net · Jun 10, 2025
Rotageek · greshamhouseventures.com · Jun 9, 2025
Wazoku · enterprisetimes.co.uk · Apr 30, 2025
Principals & officers · per Companies House
what is this? ⓘDirector · British · since 1999
Director · American · since 1999
Director · British · since 2022
Calculus Holdings Limited — 75–100% of shares, 75–100% of voting rights, right to appoint and remove directors
Frequently asked questions
- How many investments has Calculus Capital Ltd. made?
- Calculus Capital Ltd. has 41 tracked investments, 4 of which have exited, including 2 dated in the last 24 months.
- What stage does Calculus Capital Ltd. invest at?
- Calculus Capital Ltd. invests at the Seed, Series A, Series B, Series C, Late Stage stages.
- What is Calculus Capital Ltd.'s typical check size?
- Calculus Capital Ltd. typically writes checks of $2.5M.
- What sectors does Calculus Capital Ltd. focus on?
- Calculus Capital Ltd. focuses on Biotech, Data & Infrastructure, Enterprise Software, Fintech, Healthtech, IoT, Media & Entertainment, Medical Devices, SaaS, Sector Agnostic.
- Where is Calculus Capital Ltd. located?
- Calculus Capital Ltd. is headquartered in London, GB.
- Who does Calculus Capital Ltd. co-invest with?
- Calculus Capital Ltd. most often shares deals with Perscitus LLP, Boundary Capital, Maven Capital Partners, among 24 tracked co-investors.
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