National Institutes of Health (NIH) — Full Portfolio

Co-investorsSASand Hill Angels

Giner Labs is a research and development center focused on electrochemical technologies, including electrochemical sensors, electrolyzers, fuel cells, advanced materials, and medical devices.

Deep TechEnergyMedical Devices

Global Instrumentation designs and manufactures medical devices and digital platforms for cardiac monitoring and electrocardiology, serving healthcare providers and patients globally.

Digital HealthHardwareHealthtechMedical Devices

Jim DeMaso(President)Craig Sellers(Vice President, Regulatory Affairs)Scott Myers(Vice President, Operations & Program Management)

Globin Solutions, Inc. is a pre-clinical stage biopharmaceutical company developing a fast-acting antidote for carbon monoxide poisoning.

BiotechPittsburgh, US

Jason J. Rose(Executive Officer, Director)Xueli Wang(Executive Officer, Director)Mark T. Gladwin(Director)Jesus Tejero Bravo(Executive Officer, Director)

GlucoSentient develops diagnostic assays based on functional DNA (DNAzymes and aptamers) and nanomaterials for sensing applications.

BiotechDigital HealthMedical Devices

Yi Lu(Founder & Scientific Advisor)Tian Lan(Technical Lead)Steve Mayer

Co-investorsSESerra Ventures

GlycoMantra is a biotechnology company developing carbohydrate-based (glycobiology) therapeutics targeting galectin-3 for metastatic castration-resistant prostate cancer, NASH liver fibrosis, and type 2 diabetes.

BiotechHealthtech

GlycoScientific develops reagents for studying protein modifications linked to diseases such as cancer, diabetes, and neurodegenerative disorders.

BiotechDeep Tech

Lectenz Bio develops lectin-like binding proteins derived from inactivated glyco enzymes for use as research reagents in glycoscience applications.

AI & Machine LearningBiotechData & InfrastructureDeep TechSan Diego, US

Lori Yang(CEO, CSO, & Co-Founder)Robert J. Woods(President, Co-Founder, & Scientific Advisory Board Chair)Kausar N. Samli(Associate Founder)

GlycoSurf produces high-purity (>95%) bio-inspired glycolipid and rhamnolipid surfactants using a green chemistry synthetic process, with sugar head-groups including glucose, galactose, and xylose and customizable chain lengths.

BiotechCleantechNew Materials

GlycoT Therapeutics develops chemoenzymatic protein glycosylation technologies for the synthesis of homogeneous antibody glycoforms and site-specific antibody-drug conjugates for therapeutic applications.

AI & Machine LearningBiotechDeep TechHealthtechMedical Devices

Dr. Lai-Xi Wang(Founder and President)

Glyphic Biotechnologies develops ProSE™, a high-throughput de novo protein sequencing technology for analyzing proteomes with single-molecule sensitivity.

BiotechDeep TechBerkeley, US

DEDaniel Estandian(Founder)inEd Boyden(Founder)JYJosh Yang(Founder)inJoshua Yang(Founder)

BoardCACraig Asher(Director)inJYJimmy Yun(Director)in

Co-investorsARArtis VenturesBLBlack FlagCICivilization Ventures Management, LlcFOFoundersX VenturesGAGaingelsHAHarpoon Ventures+11 more

GlyTR Therapeutics is an early-stage biotech company developing a new class of anti-cancer immunotherapeutic molecules and CAR-T cells.

BiotechHealthtech

GMJ Techs develops analytical instruments that combine capillary electrophoresis with optical and mass spectrometry detection for bioanalytical applications.

BiotechDeep TechHardwareMedical DevicesSeattle, US

Carol Berry(CEO)Tosin Dada(President & CTO)

GoDx builds GoDEVICE, a portable, automated point-of-care molecular diagnostics platform that runs single-use cartridges to perform sample preparation, targeted pathogen and antimicrobial-resistance detection, NGS library preparation, and environmental surveillance.

BiotechHealthtechMedical DevicesMadison, US

Goeppert LLC provides science and technology, research and development, and commercialization services to corporations and US Federal agencies.

Deep TechGovTechNew MaterialsPhiladelphia, US

GogyUp develops assistive technology to help adults understand information and develop literacy skills for career advancement.

AI & Machine LearningEdTechSaaS

GOODdler is an enterprise platform that helps charities and NGOs manage goods donations by digitizing supply chains and enabling them to post wishlists of needed items for supporters to purchase directly from local retailers.

Impact & Social GoodMarketplacesSaaSDaly City, US

Gordian Biotechnology develops therapies aimed at treating age-related diseases to extend healthy lifespan.

AI & Machine LearningBiotechHealthtechLongevity

Co-investorsAGage1FIFifty YearsMEMetaplanetPRPrime Movers LabSTStartXSTStreamlined Ventures+3 more

BiotechRichmond, US

Michael D. Grisham(Chief Executive Officer)in

Co-investorsAMAmgen VenturesVEVensana Capital

Grace Bio-Labs develops and manufactures materials and protocols for protein microarray analysis, including slides, reagents, and related tools that support detection and imaging applications.

BiotechDeep TechMedical DevicesBend, US

Gradalis develops Vigil, a patient-specific immunotherapy studied in research and clinical trials for treating ovarian cancer, with potential use in other solid tumors.

BiotechHealthtechCarrollton, US

JNJohn Nemunaitis(Chief Scientific Officer and Co-Founder)Shanahan(Founder and Chairman)DMDavid M. Shanahan(Founder and Chairman)MEMark Early(Executive Officer)inEBErnest Bognar(Executive Officer)GWGladice Wallraven(Executive Officer)in

Co-investorsWPWP Global Partners

Gradient Biomodeling develops a computational platform for modeling biomolecular interactions and pathways.

AI & Machine LearningBiotechDeep Tech

Gradient AI develops underwriting and claims management software for group health, property & casualty, and workers' compensation insurance.

AI & Machine LearningData & InfrastructureDigital HealthEnterprise SoftwareHealthtechInsurTechDurham, US

SSStan Smith(Founder & CEO)inOuwen Huang(Executive Officer, Director)inJMJoshua Miller(Executive Officer, Director)in

BoardShana Barghouti(Director)Satish Tadikonda(Director)inMatt Bailey(Director)in

Co-investorsAMAmerican Family VenturesBOBoro CapitalCHCharlotte Angel FundMAMassMutual VenturesMEMedMountain VenturesSISilicon Valley+7 more

Gradient Medical develops INSPIRE therapy, an interventional oncology treatment that uses engineered electrical pulses to target cancer cells with real-time sensing for clinical control and adaptive energy delivery.

BiotechDeep TechHealthtechMedical Devices

Great Lakes NeuroTechnologies develops bioinstrumentation products including physiological monitors and patient-centered diagnostic and therapy systems with wireless, remote, and web-based applications.

Digital HealthHealthtechMedical Devices

GreenMark develops non-invasive dental products for dentists, hygienists, and patients that treat tooth sensitivity and support oral health management.

BiotechHealthtechMedical DevicesEast Lansing, US

SBSteven Bloembergen, PhD(Executive Officer, Director)Steven Bloembergen(Executive Officer, Director)

BoardMichael Snyder(Director)Joerg Lahann, Ph.D.(Director)Kenneth Pienta(Director)Frank van Luttikhuizen(Director)

Co-investorsIDID VenturesINInvest MichiganMIMichigan Rise

Greenstone develops induced pluripotent stem cell (iPSC)-based non-animal models combined with AI for drug discovery and development.

AI & Machine LearningBiotechDeep TechStanford, US

Dr. Joseph C. Wu(Co-founder)

Co-investorsWAWalden Catalyst

Greenwings Biomedical develops medical technology by translating university research lab intellectual property into FDA-cleared products, focusing on clinical decision support systems, biomedical devices, and digital-health products built on algorithms and machine learning.

AI & Machine LearningDigital HealthMedical Devices

RichardPaul

Greffex develops engineered adenoviral vectors for gene delivery, used to manufacture vaccines, gene therapy products, and immune suppression therapeutics.

AI & Machine LearningBiotechDeep TechDefense TechHealthtechMedical Devices

John R. Price(Co-Chairman, President, Chief Executive Officer and Co-founder)Uwe D. Staerz(Chief Scientist and Co-founder)

Gryphon Bio is a clinical-stage company that develops and manufactures blood tests based on brain-specific molecular biomarkers to monitor brain health and detect conditions such as traumatic brain injury, Alzheimer's disease, and mild cognitive impairment.

BiotechDigital HealthHealthtech

GT Molecular develops multiplex digital PCR kits for detecting and identifying respiratory pathogens such as COVID-19, influenza, and RSV in clinical and environmental samples.

BiotechDeep TechHealthtechMedical Devices

GAINS is a mobile application that delivers real-time behavioral guidance and coaching for Applied Behavior Analysis (ABA) practitioners, instructors, and caregivers across clinical and educational settings.

AI & Machine LearningDigital HealthEdTechHealthtechSaaSPhiladelphia, US

John Nosek(Founder, President and CEO, Director of Research and Product Innovation)

Guild Associates develops and manufactures engineered systems and specialized materials for applications including chemical defense, decontamination, and demilitarization.

Deep TechDefense TechEnterprise SoftwareNew MaterialsDublin, US

Gust provides a platform for startup founders to incorporate their companies, manage cap tables and equity, and handle governance, risk, and compliance.

Enterprise SoftwareFintechFuture of WorkLegalTechSaaSNew York, US

DSDavid S. Rose(Executive Officer, Director)in

BoardHMHoward Morgan(Director)in

Co-investors3737 AngelsANAngels4WomenBEBeacon AngelsBRBroad Street AngelsFAFashion Capital PartnersIUIU Ventures+11 more

GVD develops customized nano- and micro-coatings using a polymer vapor deposition technology spun out of MIT in 2001.

Advanced ManufacturingCleantechDeep TechDefense TechNew MaterialsMIT (implied), US

HabitAware makes Keen2, a vibrating awareness bracelet paired with recovery coaching and an online community to help people manage body-focused repetitive behaviors such as hair pulling, skin picking, and nail biting.

Digital HealthMental HealthWellness & FitnessSaint Louis Park, US

AIAneela Idnani(Executive Officer, Promoter)KKKirk Klobe(Co-founder & CTO)SKSameer Kumar(Co-founder & CEO)JPJohn Pritchard(Co-founder & Lead Hardware Engineer)AIAneela Idnani Kumar(Co-founder & Designer)

Co-investorsBABackstage CapitalSOSOSV

Hager Bio develops a small-molecule drug discovery platform targeting central nervous system disorders by modulating multiple signaling pathways simultaneously to achieve better therapeutic efficacy with fewer side effects.

BiotechDigital HealthHealthtech

Bel Mekonnen(Founder, President & CEO)John Butera(Chief Scientific Officer & SVP of Research)

AvantGuard develops Avantamine, an antimicrobial molecule that eliminates bacteria, viruses, and fungi on surfaces and skin without generating resistance, with an initial focus on topical treatment of the drug-resistant fungal pathogen Candida auris.

BiotechHealthtechNew Materials

Co-investorsRERed Bear AngelsBLBlue Ledge CapitalSOSOSV

Handl Health is an AI platform that aggregates and analyzes publicly available healthcare price transparency data to help insurance brokers and benefits consultants build and maintain affordable health plans for their clients.

AI & Machine LearningData & InfrastructureDigital HealthHealthtechInsurTechCerritos, US

Aishwaria Shah(Executive Officer, Director, Promoter)AMAhmed Marmoush(Executive Officer, Director, Promoter)inRia(Co-founder)inRia Shah(Founder)inScott(Technology/Engineering Leader)inAlison(Marketing Leader)in

Co-investorsARArthur VenturesBOBoutique Venture PartnersEVEverywhere VenturesPLPlug and Play VenturesRIRiverfront Ventures, LLCTATau Ventures+3 more

HaptX develops wearable haptic gloves and related technology that enable realistic touch simulation in virtual reality, spatial computing, and robotics applications.

Deep TechHardwareRobotics

JRJake RubininDr. Bob Crockett(Co-founder)

Co-investorsKEKeiretsu ForumCRCRESCENT COVE CAPITALTATaylor Frigon Capital PartnersVEVerizon Ventures

Harmonia provides advanced technology solutions for U.S. federal government agencies, specializing in AI/ML, cybersecurity, data science, and cloud modernization using Agile and DevSecOps methodologies.

AI & Machine LearningCybersecurityEnterprise SoftwareGovTechBlacksburg, US

Pallabi Saboo(Co-founder, Strategic Advisor)Jai Saboo(Co-founder, Strategic Advisor)Marc Abrams(Co-founder, Chief Technology Officer)

Co-investorsMAMadison Dearborn Partners

Hats & Ladders provides a digital career exploration curriculum and platform for K-12 students to discover career pathways, develop workplace skills, and plan their educational and professional futures.

Creator EconomyEdTechFuture of WorkSaaS

Leah Potter(President & Co-Founder)David Langendoen(CFO & Co-Founder)Scott Brewster(Director of Partnerships & Co-Founder)

Healthcare startup addressing nicotine dependence using a device that controls nicotine dosage via smartphone app for gradual reduction.

Co-investorsMOMonozukuri Ventures

hc1 offers hc1 IQ, an AI-based platform that turns laboratory and diagnostic data into clinical, operational, supply chain, and market-growth intelligence for health systems and providers.

AI & Machine LearningDigital HealthHealthtech

BBBradley Bostic(Chairman and CEO)in

Co-investorsA1A1 Health VenturesELElevate Ventures

HDT Bio is a clinical-stage biopharmaceutical company developing novel immunotherapy technologies and products to treat oncology and infectious diseases.

BiotechHealthtechMedical DevicesSeattle, US

Bryan BerubeDavid LaPointeKelli CarabelloShamini Thiagarajan

Healcisio develops AI-driven clinical decision support systems for hospitals, including sepsis prediction, quality reporting automation, and outpatient monitoring.

AI & Machine LearningDigital HealthHealthtech

Michael McCurdy(MD)Hayden PourJennifer AttiasGeorgia PoirierNabil AsadiNeha Shashikumar

Healionics develops STARgraft, a synthetic vascular graft built on its STAR biomaterial scaffold that resists occlusion and infection to create a reliable bloodstream access site for kidney dialysis patients.

BiotechMedical DevicesNew MaterialsSeattle, US

BRBuddy Ratner(Director)MCMike Connolly(Executive Officer, Director)inAndrew Marshall(Director)Max Maginness(Executive Officer)

BoardRyan Takeuchi(Director)Arthur Coury(Director)

Co-investorsALAlliance of AngelsBABand of AngelsCECentral Texas Angel NetworkISiSelect FundKEKeiretsu ForumMEMEDA Angels+1 more

Health Discovery Labs develops MyokinE, an adaptive electrical muscle stimulation system that automatically activates muscles in sedated or immobile ICU patients to preserve strength and reduce ICU-acquired weakness.

Digital HealthHealthtechMedical Devices

Oussama Hassan(Co-Founder & Chief Medical Officer)Alaa Hassan(Co-Founder & Chief Technology Officer)

TeleSage develops software tools for behavioral health outcomes tracking and research, serving clinicians and researchers worldwide.

Digital HealthHealthtechMedical DevicesMental Health

Dr. Benjamin Brodey(Founder)

Real-time objective behavioral health monitoring

HealthtechLong Island City, US

MMMark Mathews(Director)Paul Gilbert(Executive Officer, Director)

Co-investorsCUCU Healthcare Innovation FundINInformed Ventures Advisors, LlcWAWaterline VenturesCICity LightINInflect Health

HealthMyne develops QIDS, a quantitative imaging and clinical decision support platform for oncology care teams that tracks incidental findings, supports tumor conference preparation, and provides quantitative imaging metrics such as lesion volume and texture analysis.

AI & Machine LearningDigital HealthHealthtechMedical DevicesMadison, US

RCRoger Chylla(Executive Officer, Director)inHao Wang(Executive Officer)inPSPraveen Sinha(Executive Officer, Director)inASArvind Subramanian(Executive Officer, Director)inThomas Rockwell Mackie(Director)

BoardGreg Robinson(Director)

Co-investorsALAlumni VenturesASAscension VenturesBABascom Ventures444490 Ventures

HealthtechChandler, US

David Smith(Executive Officer)inBill Colston(Executive Officer, Director)in

BoardCraig Asher(Director)Caren Masen(Director)Carolyn Compton(Director)Paul Conley(Director)

Co-investorsTHThird Point VenturesVIVital Venture Capital

ComplyFoam manufactures replacement memory foam ear tips for popular wireless earbuds models including Apple AirPods Pro, Sony, and Bose.

ConsumerDirect to ConsumerHardware

HeartLander is a robotic walker surgical device in pre-clinical development that attaches to the epicardium through a small percutaneous port and moves across a beating heart to enable minimally invasive procedures such as cardiac ablation, myocardial regeneration therapy delivery, and biventricular pacing lead placement.

HealthtechMedical DevicesRobotics

Heligenics is a genomics and cell biology company that develops assays and platforms for drug screening and genetic analysis.

AI & Machine LearningBiotechDeep TechMedical DevicesLas Vegas, US

Martin Schiller, Ph.D.(Founder & CEO)Lawrence John Loomis(Chief Operating Office & Corporate Secretary)Martin Schiller(Executive Officer)

HelixBind develops a diagnostic platform for bloodstream infections that delivers microbiology results in about 4 hours to help clinicians identify invasive infections and choose antimicrobial treatments.

BiotechHealthtechMedical DevicesMarlborough, US

Alon Singer(Executive Officer, Director, Promoter)inLarry Pearson(Director)Sheppard Mollick(Director)

Co-investorsARArieal Southeast Angel Partners

Helixomer is a preclinical RNA nanodrug company developing fully synthetic, reversible anticoagulants and reversal agents to replace heparin in acute critical care.

BiotechDeep TechHealthtechResearch Triangle Park, US

Hememics develops FAST (Functionalized Analyte Screening Technology), an immunoassay-based screening platform that lets researchers use their own antibodies and antigens to screen antibody mini-panels in under an hour.

BiotechDeep TechMedical Devices

JLJohn L. Warden, Jr.(Founder & CEO, Chairman of the Board)inDavid Ho(Founder, President & CSO)inRLRichard Liu(CFO & Board Member)in

Co-investorsMAMaryland TEDCOTETEDCO

Hemex Health develops and commercializes the Gazelle diagnostic platform, including point-of-care readers and tests for conditions such as sickle cell disease and hemoglobin variants.

Digital HealthHealthtechMedical DevicesPortland, US

PWPatricia White Seminario(Executive Officer, Director, Promoter)PGPeter Galen(Chief Innovation Officer, Co-Founder)inPWPatti White(Chief Executive Officer, Co-Founder)inDaren Bledsoe(Sr. VP, Engineering & Operations)inGVGerrit van Roekel(VP, Business Development)inUGUmut Gurkan(Chief Scientist, Microfluidics)in

Co-investorsCWCWRU Technology VenturesELElevate CapitalIDIdeashipIMImpact India Investment PartnersPOPortland Seed Fund

HemoSonics develops FDA-cleared viscoelastic testing (VET) technology that provides real-time hemostasis data at the point of care for hospital teams managing bleeding in obstetric, trauma, and surgical settings.

HardwareHealthtechMedical DevicesCharlottesville, US

FVFrancesco Viola(Manager)inTimothy J. Fischer(Manager)William F. Walker(Manager)

BoardJosep Manent(Manager)William P Moffitt(Manager)Mark Wheeler(Director)

Henley Ion develops patented miniaturized Electrostatic Precipitator (mEP) technology used in respiratory protection and air purification systems designed to protect against nuclear, biological, and chemical contaminants as well as toxic industrial materials.

CleantechHardwareHealthtech

Julian Henley(Founder)

BiotechPlymouth, US

Douglas Wicks(Founder)Patrick M. Schlievert(Founder)William Falkner(Founder and Chairman of the Board)TBThomas Burke(Executive Officer, Director)

BoardJohn Bullion(Director)Williamson Bradford(Director)

HepaTx develops stem cell-based hepatocyte therapies for liver disease treatment as an alternative to organ transplantation.

BiotechHealthtechMedical DevicesSan Francisco, US

ESEric Schuur(CEO)inMark Chao

Co-investorsISiSelect FundSASand Hill AngelsSTStartXY Y CombinatorPAPalapa VenturesSPSP Investment Fund

Hesperos develops "Human-on-a-Chip" organ-on-a-chip platforms, offering custom multi-organ models (up to 5 organ or tissue types) with functional readouts such as gene expression and electrophysiology.

BiotechDeep TechMedical DevicesOrlando, US

MLMichael L. Shuler(Co-founder)inJJJames J. Hickman(Chief Scientist)inLFLawrence Florin(Chief Executive Officer)inJSJames Stanker(CFO)

Co-investorsBTBtomorrow Ventures

Co-investorsGRGrowth Factory Ventures

Hinge Bio is a biotechnology company developing next-generation therapeutics based on its GEM-DIMER platform, aimed at improving efficacy and reducing resistance and side effects.

BiotechHealthtechBurlingame, US

Daniel J. Capon(Director)CMCarin Mueller Rollins(Co-Founder & Chief Operating Officer)HEHarold E. Selick, PhD(Executive Officer, Director)Miriam Siekevitz(Executive Officer)inHarold E. "Barry" Selick(Chief Executive Officer & Director)PBPaul Brunetta(Chief Medical Officer)in

Co-investorsPOPoint72AGAgent CapitalBABaruch Future VenturesINInVivium CapitalRIRidgeback Capital

Honeycomb Biotechnologies develops the HIVE Single Cell Solution, a single-cell RNA sequencing (scRNAseq) technology that captures, stores, and sequences cells for transcriptomic analysis.

BiotechDeep TechHardware

Hospi Corporation develops FDA-cleared medical devices for hospice and palliative care patients, focusing on improving comfort and easing caregiver burden.

HealthtechMedical DevicesSan Mateo, US

Brad Macy(Co-founder)

Ensera Design is a healthcare product design and development consultancy that helps medical device, pharmaceutical, and consumer health organizations develop market-ready products, from human factors research through design for manufacture.

HardwareHealthtechMedical Devices

Hsiri Therapeutics is a biotech company discovering and developing therapies for drug-resistant bacterial and fungal infections, with focus areas in tuberculosis, non-tuberculous mycobacterial (NTM) diseases, and drug-resistant fungal pathogens.

BiotechHealthtechMedia, US

William Claypool(President & CEO)Ivan Joseph(Chief Financial Officer)

Humanetics is an advanced clinical-stage pharmaceutical company developing drugs to protect and treat injuries from radiation, chemical, and biological threats.

BiotechDefense TechHealthtechMedical DevicesMinnesota, US

Colin Chinn(Chief Medical Officer)

Hummingbird Scientific develops advanced in-situ microscopy instrumentation for electron, X-ray, and ion microscopy, enabling real-time nanoscale observation for scientific research.

AI & Machine LearningDeep TechHardwareNew Materials

VWIN is an online gambling brand offering sports betting, live casino games, lottery, fish-shooting and slot titles to players, with lottery-prediction content for the Vietnamese market.

ConsumerGamingManila, PH

Hunterian Medicine develops a CRISPR delivery technology using adeno-associated viruses to enable in vivo gene editing for treating genetic diseases.

AI & Machine LearningBiotechDeep TechMedical DevicesBaltimore, US

Dr. Vinod Jaskula-Ranga(Founder, President and CEO)

BiotechCalabasas, US

Danny JJ Wang(Executive Officer, Director)Conn Davis(Director)Marc Korczykowski(Executive Officer, Director)

Philadelphia, US

Keith Fitzgerald(Executive Officer, Director)Daniel DeLauro(Executive Officer, Director)Ryan Katrina(Executive Officer, Director)Gregory Thompson(Executive Officer, Director)

Co-investorsSESeae Ventures

HydroCision develops minimally invasive surgical instruments using proprietary FluidJet technology to selectively remove soft tissue in a precise manner.

BiotechHardwareHealthtechMedical DevicesNorth Billerica, US

PAUL KOWALSKI(Executive Officer)inRICHARD A. LYTLE, III(Executive Officer, Director)TDTHOMAS D. ABERT(Executive Officer)inPATRICIA VANBLARCOM(Executive Officer)RLRick Lytle(President & Chief Executive Officer)in

BoardLONG ZHAN(Director)

Co-investorsBIBioVenturesNENewbury VenturesOXOxford Bioscience Partners

Hydrostasis develops technology focused on helping aging adults maintain health through hydration monitoring, leveraging expertise in optical technology, data science, and biology.

Deep TechHardwareHealthtechIoTLongevityWellness & Fitness

Debbie K. Chen, PhD(Founder)in

Co-investorsADAd Astra VenturesIGigniteXL VentureSOSOSV

HylaPharm is a University of Kansas spinout developing cancer therapies that reverse tumor-induced immune suppression to make "cold" tumors responsive to the immune system, with the goal of improving response to checkpoint inhibitors in human patients.

BiotechDeep TechHealthtechLawrence, US

HYPRES designs and manufactures superconductor integrated circuits and related cryogenic equipment for high-speed digital and mixed-signal applications.

Deep TechDefense TechHardwareSemiconductors

ISS designs and manufactures scientific instrumentation for research and clinical applications, including fluorescence spectroscopy systems and biomedical measurement devices.

BiotechDeep TechHardwareHealthtechMedical Devices

i3 develops a hybrid intravascular imaging catheter combining near-infrared fluorescence (NIRF) and ultrasound (IVUS) sensors to provide real-time molecular and structural imaging during coronary interventions.

AI & Machine LearningDeep TechHealthtechMedical DevicesBoston, US

Co-investorsBRBroadview Ventures

IASO Therapeutics develops synthetic antigen vaccines using a mutant Qβ virus-like particle carrier platform to generate targeted, durable immunity.

BiotechHealthtechEast Lansing, US

Robert Forgey(President & CEO)Xuefei Huang(Executive Officer, Director)Herbert Kavunja(Executive Officer)

BoardDonald Parfet(Director)JWJeffrey Wesley(Director)inSteve Kuemmerie(Director)

Co-investorsMIMichigan RiseWMWMU Biosciences Research & Commercialization Center

Iaterion is a biopharmaceutical company developing small-molecule drugs for women's health and cancer indications.

BiotechFemTechHealthtechMedical DevicesBerkeley, US

Isaac Cohen(CEO)Dale Leitman(Chief Scientific Officer)

IBC develops and manufactures Molecular Recognition Technology (MRT) products, processes, and engineered systems for highly selective separation of metals, cations, anions, and bio molecules based on green chemistry principles.

Advanced ManufacturingCircular EconomyCleantechDeep TechNew Materials

Dr. Reed M. Izatt(Founder)Dr. Jerald S. Bradshaw(Founder)Dr. James J. Christensen(Founder)Steven R. Izatt(President and CEO)

Ichor Life Sciences is a vertically integrated contract research organization providing pre-clinical R&D services including protein expression, biophysics, cell-based assays, and in vivo studies in mice and rats for pharmaceutical companies.

BiotechDeep TechDigital HealthHealthtechMedical DevicesSyracuse, US

Kelsey Moody(Chief Executive Officer)

BiotechNashville, US

JEJames E. Crowe, Jr.(Director)Charles F. Haines(Executive Officer, Director)Kenneth J. Kelley(Director)Mike LaBarre(Director)

iFyber is a product development and research services firm that helps companies commercialize technologies at the intersection of chemistry, biology, and materials science.

BiotechDeep TechHealthtechMedical DevicesNew MaterialsIthaca, US

Aaron Strickland(Co-founder & Vice President of Research and Development)

iHealthScreen offers iPredict, an AI-based system that analyzes retinal images captured by a medical assistant to diagnose eye disease status and generate diagnostic reports with referral recommendations.

AI & Machine LearningDigital HealthMedical Devices

Imagine Scientific develops a patented monochromatic X-ray mammography instrument, spun off from astrophysics research, that provides 2-D and 3-D breast imaging with lower radiation doses.

Deep TechHealthtechMedical Devices

iBMarker is a unified platform purpose-built for IB educational institutions to assess student work against IB rubrics with integrated AI assistance, auditing, and governance controls.

AI & Machine LearningEdTechSaaS

BiotechOrlando, US

CGCodi Gharagouzloo(Executive Officer, Director, Promoter)inScott Hoge(Executive Officer)Valerie Aimee Gharagouzloo(Executive Officer, Director, Promoter)

Co-investorsIDIdeaship

Imanis Life Sciences is a contract research organization staffed by virologists, immunologists, molecular biologists, and assay scientists that provides laboratory and development services to help clients accelerate therapy development.

BiotechHealthtechRochester, US

Dr. Stephen Russell(Executive Officer, Director, Promoter)in

Imbed Biosciences is a medical device company that develops SAMatrix, an ultra-thin, fully synthetic bioresorbable wound matrix that integrates antimicrobial silver and non-opioid pain agents (lidocaine) for treating chronic and acute wounds such as ulcers, surgical, traumatic, and burn wounds.

BiotechHealthtechMedical DevicesMadison, US

NLNicholas L Abbott(Executive Officer, Director)inAAAnkit Agarwal(Executive Officer, Director)in

BoardDavid Guinther(Director)Robert A Beckman(Director)

Co-investorsWIWisconsin Investment Partners

Imbio provides analytical software that extracts quantitative lung function data from standard X-ray scans to support non-invasive diagnosis and treatment planning for clinicians.

AI & Machine LearningDigital HealthMedical DevicesMinneapolis, US

DHDavid Hannes(Executive Officer)inTroy D. Kopischke(Executive Officer, Director)Cynthia Maier(Executive Officer, Director)Mark Sylvester(Executive Officer)Danny J. Cunagin(Executive Officer, Director)Alnawaz Rehemtulla, M.D.(Director)

Co-investorsSESeneca Partners

ImCare Biotech develops diagnostic biomarkers and therapeutic drugs targeting liver diseases, including hepatocellular carcinoma and intrahepatic cholangiocarcinoma.

AI & Machine LearningBiotechDigital HealthMedical DevicesDoylestown, US

XLXuanyong Lu(President & Co-Founder)inAYAaron Yefei Lu(Chief Executive Officer)Karteek Kadimisetty(Chief Science Officer)inXuanyong Lu, PhD(Executive Officer, Director)

BoardFelix Y. Lu(Director)

iMetabolic Biopharma Corporation develops pharmaceutical candidates targeting metabolic and lipid-related disorders, including obesity, cardiovascular disease, and neurodegenerative conditions.

AI & Machine LearningBiotechDeep TechHealthtechMedical Devices

Urban A. Kiernan(Dr.)

ImgGyd develops hardware and software for image-guided neurosurgery, including trajectory guides for mm-level precision and custom sterile drapery.

HardwareHealthtechMedical DevicesMadison, US

Immertec develops virtual reality training solutions for medical education, enabling healthcare professionals to practice procedures through immersive technology.

AI & Machine LearningDigital HealthEdTechHealthtechMedical Devices

Erik Maltais(CEO / Co-Founder)Jon Clagg(CTO / Co-Founder)

Co-investorsRERevolution

Antigen Discovery provides proteome microarray technology and research services for biomarker discovery, vaccine development, and therapeutic antibody identification.

BiotechDeep TechMedical DevicesIrvine, US

Xiaowu Liang(Co-founder, Chairman & CEO)Angela Yee(Co-founder, Board Member, COO & CFO)

Immunartes develops preventive therapies against Staphylococcus aureus by neutralizing the pathogen's immune-evasion mechanism, using two modalities: a vaccine for durable immunity and a monoclonal antibody for immediate protection in perioperative and other high-risk hospital settings.

BiotechHealthtechChicago, US

Dominique Missiakas(Founder and Chief Scientific Officer)Vilasack Thammavongsa(CEO and Director of Research)

Immune Onc is a biotechnology company developing medicines to treat patients with hard-to-treat cancers and autoimmune diseases, with expertise in translational medicine and clinical development.

BiotechMedical DevicesPalo Alto, US

XCXiaoling Charlene Liao(Executive Officer, Director)Charlene Liao(Founder)in

BoardGuo-Liang Yu(Director)Liqun Luo(Director)

Co-investorsCLCLI VenturesNONorthern Light Venture CapitalSHShangBay Capital LLCSTStartXVIVivo CapitalTRTriWise Capital

Immuno Technologies, Inc (ITi) is a for-profit company conducting preclinical research on preventatives such as vaccines and monoclonal antibody therapies, along with diagnostic assays for spirochetal diseases including Lyme disease and leptospirosis affecting animal and human health.

BiotechHealthtechMedical DevicesMemphis, US

Immunomic Therapeutics develops nucleic acid immunotherapy platforms, particularly self-amplifying RNA and plasmid DNA vaccines, for cancer treatment, allergies, and animal health applications.

BiotechMedical DevicesRockville, US

William G Hearl(Chief Executive Officer and Director)inDKDong-Gun Kim(Executive Officer, Director)inC. ERIC WINZER(Chief Financial Officer and Director)inBernard C Rudnick(Chief Financial Officer)Teri Heiland(Vice President of Research and Development)inBruce Mackler(Vice President and Director)

Co-investorsKEKeiretsu ForumLILife Sciences Greenhouse Investments

Immunophotonics is a clinical-stage biotech company developing novel treatments for solid-tumor cancers and infectious diseases by combining tumor ablation with systemic cancer immunotherapy.

BiotechDeep TechDigital HealthMedical DevicesSt. Louis, US

Dr. Hode(Co-Founder & Senior Fellow)Mr. Alleruzzo(Co-Founder & Director)Dr. Chen(Co-Founder)Dr. Robert Nordquist(Co-Founder)Luciano Alleruzzo(Director, Promoter)WCWei Chen(Director, Promoter)

Co-investorsARArgonautic VenturesBIBioGenerator VenturesCECentennial InvestorsISiSelect FundMIMissouri Technology CorporationCUCultivation Capital

Immusoft develops a cell therapy platform called Immune System Programming (ISP) that engineers a patient's B cells into plasma cells that produce therapeutic proteins after being infused back into the patient.

BiotechDeep TechHealthtechSeattle, US

MSMatthew Scholz(Founder)inSASean Ainsworth(Chief Executive Officer)inRSRobert Sikorski(Chief Medical Officer)RHRob Hayes(Chief Scientific Officer)inSMScott McIvor(Chief Development Officer)Eric Garcia(Executive Officer)in

Co-investorsBIBioRock VenturesBOBoston Harbor AngelsBRBreakout VenturesEQEQx FundINInvariantes FundMIMichigan Capital Network+7 more

Immuto Scientific uses patient-derived tissue models combined with computational structural proteomics and machine learning to identify disease-specific protein targets for drug discovery.

AI & Machine LearningBiotechDeep Tech

FAFaraz A Choudhury(CEO & Founder)inDBDaniel Benjamin(Co-Founder & CTO)in

Co-investorsDYDYDX CapitalGRGreat Oaks Venture CapitalTUTundra AngelsVEVenture ManagementWIWisconsin Investment Partners

Immvention Therapeutics develops first-in-class BACH1 inhibitors intended as an oral therapy for patients with sickle cell disease and other conditions.

BiotechDigital HealthChapel Hill, US

Jenny Ting(Director and Co-founder)Matthew Cohen(Director)Lev Osherovich(Director)Mark Vellaca(Director)Anil Goyal(CEO and Director)

BoardBenjamin Scruggs(Director)

Co-investorsDEDelin VenturesHAHatteras Venture PartnersOUOUP (Osage University Partners)

IBIS offers EICON, a modular platform for biomedical imaging data operations that automates DICOM workflow management, clinical data de-identification, QC, and pre-processing to make imaging data AI-ready.

AI & Machine LearningHealthtechMedical Devices

Impel Pharmaceuticals develops therapies for diseases with high unmet medical needs by pairing established drugs with its proprietary upper-nasal drug delivery technology.

BiotechHealthtechMedical DevicesSeattle, US

JDJohn D. Hoekman(Executive Officer, Director)in

BoardMichael Hite(Director)Stewart Parker(Director)

Co-investors5A5AM VenturesB B Capital GroupVEvenBio Global StrategicVEvenBio PartnersWEWestlake Village BioPartners

Impressio develops and commercializes Liquid Crystal Elastomers (LCEs) for use in sports equipment, military gear, medical devices, and wearables to improve impact protection, vibration damping, and thermal management.

Deep TechHardwareMedical DevicesNew Materials

Josh Ray(Chairman & CEO)

Imricor develops MRI-guided cardiac electrophysiology products, including the Vision-MR ablation and diagnostic catheters, the NorthStar Mapping System, and the Advantage-MR EP Recorder/Stimulator, used to perform catheter ablation procedures under real-time MRI.

HardwareHealthtechMedical DevicesBurnsville, US

Steven R. Wedan(Executive Officer, Director)Mark Tibbles(Director)Niels Kuster(Director)Thomas Borillo(Director)

Imtherapeutics develops oral therapies for Type 1 diabetes patients with specific genetic markers.

Biotech

Co-investorsJDJDRF T1D Fund

InvivoAX provides an AI-native platform that automates segmentation and extraction of radiomic biomarkers from multimodal biomedical imaging (CT, MRI, PET, and optical scans), converting raw images into structured, analysis-ready datasets.

AI & Machine LearningBiotechHealthtech

Inanovate is a diagnostics company that developed Lyme-ID, an FDA 510(k)-cleared blood test for Lyme disease based on its proprietary Bio-ID technology.

BiotechSioux Falls, US

David Ure(Executive Officer, Director)inJames E Oury(Executive Officer)

BoardBlaine Crissman(Director)Katie Pohlson(Director)Peter D. Los(Director)David Arslanian(Director)

Inceptus Medical is a medical device incubator founded in 2011 that identifies and develops early-stage medical device companies.

Deep TechMedical Devices

Brian Cox(Founder)Robert F. Rosenbluth(President and CEO)Paul Lubock(Principal)

Incom manufactures glass and polymer microstructures used in optical and display applications for medical, dental, scientific, and defense industries.

Deep TechDefense TechHardwareMedical DevicesNew MaterialsCharlton, US

Indee Labs develops Hydropore™, a non-viral microfluidic technology for delivering molecules, nucleic acids, proteins, and gene-editing complexes into immune cells for engineered cell therapy research and manufacturing.

BiotechDeep TechHealthtechMedical DevicesSan Francisco, US

RPRyan Pawell(CEO)inAdrian Lievano(Bioengineer)Amy Twite,Eva Welles(HR Consultant)

Co-investorsJUJude GomilaPIPioneerSOSOSVY Y CombinatorBRBroadOak Capital PartnersFOFounders Fund+1 more

Indelible Learning offers a year-round online platform (ILI) with games, simulations, and courses that immerse students in real-world career scenarios across fields like medicine, science, civics, and leadership.

EdTechGaming

InferLink applies artificial intelligence and statistical inference to solve complex problems for clients across multiple sectors.

AI & Machine LearningData & InfrastructureDeep TechEnterprise Software

Steven Minton(President and Founder)

IBT develops advanced prosthetic devices for people with upper limb differences, using proprietary control algorithms and flexible electronics technology.

BiotechDeep TechHealthtechMedical DevicesBaltimore, US

Nitish Thakor(Co-Founder, Professor of Biomedical Engineering)Ananth Natarajan(Co-Founder, Physician and Engineer)

Inflammatix develops host-response-based molecular diagnostics tests to identify acute infections and sepsis in emergency and critical care settings.

AI & Machine LearningBiotechHealthtechMedical DevicesBurlingame, US

TSTim Sweeney(Co-Founder and CEO)inPKPurvesh Khatri(Founder)inJRJONATHAN ROMANOWSKY(Co-Founder)inTimothy Sweeney(Founder)

BoardKENNETH BAHK(Director)MICHAEL RUBIN(Director)

Co-investorsKHKhosla VenturesNONorthpond VenturesINInitiate Venture PartnersMAMarram VenturesOSOSF VenturesSTStartX+1 more

InfraTrac develops spectroscopic authentication and anti-counterfeiting solutions for additive manufacturing and pharmaceuticals.

Advanced ManufacturingDeep TechHardwareMedical DevicesWashington, DC, US

Sharon Flank(Founder & CTO)inJonGary

Co-investorsTETEDCO

ingenious targeting laboratory (iTL) is a U.S.-based company that generates genetically engineered mouse models for biomedical research institutions and pharmaceutical companies.

BiotechDeep TechHealthtechHolbrook, US

Jennifer Parla(Dr.)Milen Kirilov(Dr.)Arielle Bryan(Dr.)

INHERET provides an online tool that collects detailed family health histories and evaluates hereditary cancer risk, then links to best-practice guidelines so providers can recommend next steps.

BiotechDigital HealthHealthtech

David Keren(Co-founder, MD)Kelly(CEO)Amanda

Co-investorsWMWMU Biosciences Research & Commercialization Center

Inhibikase Therapeutics is a clinical-stage pharmaceutical company developing protein kinase inhibitor therapeutics for pulmonary arterial hypertension (PAH).

BiotechHealthtechAtlanta, US

MHMilton H. Werner Ph.D(Executive Officer, Director)inJoseph Frattaroli, C.P.A.(Executive Officer)Dennis Berman(Director)Gisele Dion(Director)

BoardPaul Grint, M.D.(Director)Roy Freeman M.D.(Director)

Co-investorsRARA Capital

Inhibrx develops protein therapeutics, using target biology and protein engineering to create therapeutic candidates in clinical trials for conditions including sarcoma and head and neck cancer.

BiotechLa Jolla, US

MLMark Lappe(Executive Officer, Director)inBrendan Eckelman(Director)inDoug Forsyth(Director)Jon Faiz Kayyem(Director)Margery Fischbein(Director)

BoardJudith Li(Director)

Co-investorsLALAVLILilly Asia VenturesRARA CapitalVIViking GlobalOXOxford Finance LLC

Inimmune is a clinical-stage biotech company developing immunotherapies for allergy, cancer, infectious, and autoimmune diseases.

AI & Machine LearningBiotechDeep TechHealthtechWhitefish, US

Jay EvansinDBDavid BurkhartinHBHelene Bazin-LeeinKRKendal Ryterinalan joslynin

Co-investorsTWTwo Bear Capital

Injectsense develops implant-based digital health systems that use semiconductor technology to provide medical staff with continuous long-term monitoring data for therapy management, with an ophthalmology focus including eye-pressure markers.

Digital HealthHardwareMedical DevicesSemiconductorsEmeryville, US

Enrique Malaret(Executive Officer, Director)Ariel Cao(Executive Officer, Director)inZack Scott(Director)

InkSpace Imaging develops MRI coil technology and patient-centered diagnostic imaging solutions, drawing on expertise in MRI coil design, medical device manufacturing, and regulatory compliance.

HardwareHealthtechMedical DevicesPleasanton, US

Peter Fischer(Executive Officer, Director)George Rehm(Director)Jacques Coumans(Director)Shimon Michael Lustig(Director)Scott Gorton(Executive Officer)

InnAVasc develops a vascular access graft for hemodialysis, featuring self-sealing pods and puncture-resistant backplates that guide dialysis needle placement to reduce needle-injury and bleeding complications.

BiotechHardwareHealthtechMedical DevicesDurham, US

Shawn Gage(Executive Officer)Jeffrey Lawson(Executive Officer, Director)Joseph Knight(Executive Officer, Director)Roberto Duane Manson(Executive Officer)

BoardDani Bolognesi(Director)

Co-investorsARArieal Southeast Angel PartnersDUDuke Capital PartnersHAHatteras Venture Partners

An R&D firm that commercializes engineered technologies and research into market-ready solutions addressing real-world problems.

Deep TechDefense TechMedical DevicesNew MaterialsTorrance, US

Dr. Kisholoy Goswami(Cofounder)Uma Sampathkumaran(Senior Vice President of R&D)

Innov8 AI develops artificial intelligence solutions focused on environmental, social, and governance (ESG) applications and improving societal resilience.

AI & Machine LearningCleantechData & InfrastructureImpact & Social GoodMarketing TechMedia & EntertainmentLos Gatos, US

Dr. Andy Skumanich(CEO)

iRT Inc. provides research consultation, evaluation, and technical services to organizations seeking to develop, validate, and implement health and social programs.

Data & InfrastructureDigital HealthEdTechGovTechHealthtechImpact & Social GoodMental HealthDurham, US

Janis Kupersmidt(Founder)

Innovative Biochips develops microfluidic technologies for biomedical research and diagnostics applications.

BiotechDeep TechHardwareLongevityMedical DevicesHouston, US

Innovative Design Labs is an R&D company that designs and prototypes products for consumer, medical, and education markets, offering services in software development, embedded sensors, mechanical design, and wearable technology to researchers, manufacturers, and commercialization partners.

Deep TechEdTechHardwareHealthtechIoTMedical DevicesMinneapolis, US

Innovative Scientific Solutions Incorporated (ISSI) is an engineering R&D company providing measurement and instrumentation solutions for fluid dynamics, aerodynamics, combustion analysis, and optical diagnostics.

Deep TechDefense TechEnterprise SoftwareHardwareDayton, US

Inovodel develops a compact, portable system for generating and delivering inhaled nitric oxide to treat pulmonary conditions including pulmonary hypertension and hypoxic lung failure.

BiotechDeep TechHealthtechMedical Devices

InRedox develops and commercializes self-organized nanoceramic materials, including nanoporous anodic aluminum oxide, for advanced technology and research applications.

Deep TechHardwareNew MaterialsNorthern Front Range of Colorado, US

Dmitri Routkevitch(Co-Founder, President & CTO)F. Howland "Howie" Carpenter(Co-Founder, VP Business Development)Michael H. B. Stowell(Co-Founder, Chair of Scientific Advisory Board)

Insightfil instruments medication convenience packaging ("strip" packs) with a proprietary NFC tag that patients or caregivers tap with a smartphone to verify the right medications were taken at the right time and collect adherence data.

Digital HealthHealthtechIoT

Insilica develops autonomous computational infrastructure for toxicology risk assessment, automating evidence-based decision-making from literature review through regulatory submission.

AI & Machine LearningBiotechData & InfrastructureDeep TechHealthtech

InsiteHub provides learning technology solutions and consulting services for organizations in life sciences and healthcare industries, focusing on enterprise learning strategy, digital transformation, and workforce development.

EdTechEnterprise SoftwareHealthtechHR TechSaaSNewark, US

John Royer(CEO/Managing Partner)

Inso Bio develops low-cost workflow automation tools for genomics laboratories to accelerate sample-to-result processing and increase accessibility to genomic analysis.

AI & Machine LearningBiotechDeep TechHardwareMedical DevicesIthaca, US

Harvey Tian(Co-Founder and CEO)inAdam Bisogni(Co-Founder and CSO)in

Co-investors202048 VenturesSOSocial StartsSOSOSVSPSpacecadet Ventures

A professional services site for Alexandra, a business and career expert offering keynote speaking, consulting, and media engagements focused on the global workforce and workplace training.

Future of WorkHR Tech

BiotechPortola Valley, US

Lena Wu(Executive Officer, Director)Erik Gentalen(Director)Michael Rubin(Director)

BoardJRJenny Rooke(Director)in

Co-investorsHEHemisphere Ventures LLCVEVertical Venture PartnersGEGenoa VenturesNONorthpond Ventures

Intact Genomics develops genomic products and services for DNA/RNA amplification, disease diagnostics, drug discovery, and molecular cloning used by researchers and laboratories.

AI & Machine LearningBiotechDeep TechSt. Louis, US

Dr. Wu

Intact Therapeutics develops next-generation biopharmaceutical therapies for gastrointestinal diseases to address unmet clinical needs.

BiotechHealthtechSan Francisco, US

RPRavi Pamnani(CEO)inSSSidhartha Sinha(Founder)inNavdeep Kaur(Director of R\u0026D)

Co-investorsBRBrightstone Venture CapitalY Y CombinatorHAHanmi HealthcareSTStanford UniversityVEVenture Investment Associates

Intan Technologies manufactures integrated circuit chips for electrophysiology signal recording that combine amplifiers, filters, analog-to-digital conversion, and impedance measurement on a single chip.

Deep TechHardwareMedical DevicesSemiconductorsLos Angeles, US

Reid Harrison

Integral BioSystems is a contract research organization specializing in drug delivery and complex pharmaceutical product development, serving the pharmaceutical and biotech industry from the pre-clinical stage through product formulation.

BiotechDeep TechHealthtechMedical DevicesBedford, US

Shikha P. Barman(Founder, President and CEO)Dave Karasic(Co-Founder, Chief Operations Officer, Legal Counsel and IP)

Integral Molecular is a biotechnology company developing innovative technologies and therapeutic antibodies targeting membrane proteins such as GPCRs, ion channels, transporters, and viral envelopes for drug discovery.

BiotechDeep TechPhiladelphia, US

Benjamin Doranz(Co-founder)

IDES develops time-resolved electron microscopy products and services, including add-ons and systems for transmission and scanning electron microscopes used in advanced imaging experiments.

Deep TechHardwareNew Materials

Inotiv provides preclinical pathology services, offering ACVP board-certified pathologists for semi-quantitative and quantitative evaluation across a range of studies, tissues, species, and disease states.

BiotechHealthtechMedical Devices

IMCS develops sample preparation products and automation solutions for laboratory workflows, including custom tips, enzymes, and buffers.

BiotechDeep TechHardwareMedical DevicesSaaSColumbia, US

Andrew LeeQian WangWilliam Brewer