Life Sciences Greenhouse Investments
Venture capitalHarrisburg · Pre-Seed–Series B · 11 people tracked
Investment thesis
LSGI aims to strengthen Pennsylvania's life sciences ecosystem and improve patient healthcare outcomes by providing early-stage capital that bridges the gap between pre-seed and Series B funding. It focuses on young Pennsylvania companies in drug discovery, diagnostics, medical devices, product commercialization, and IT-driven solutions to large-scale healthcare challenges. Beyond funding, LSGI offers operational expertise and access to a curated network of business and scientific advisors, drawing on deep understanding of both science and entrepreneurship to help early-stage companies navigate their challenges.
Source: firm website, verified Aug 11, 2026.
Team · 11 people
from the firm's website
What they invest in
from 17 of 26 portfolio companiesMedical Devices ×14Healthtech ×10Biotech ×9AI & Machine Learning ×5Digital Health ×5Deep Tech ×4Advanced Manufacturing ×2AdTech ×1
HQs:United States×11Chile×1
Investments · 26 tracked
founders shown can be your intro pathBy year:2026 · 12025 · 12023 · 12022 · 22019 · 12018 · 17 dated
Mediaspace is a digital agency that designs and builds custom Squarespace websites and provides SEO, digital marketing strategy, and digital advertising services.
AdTechAdvanced ManufacturingAI & Machine LearningData & InfrastructureDigital HealthEnterprise SoftwareHardwareHealthtechMarketing TechMedical DevicesSemiconductorsAtlanta, US
Ronald P. Thiboutot(Director)William D. McPhee(Director)John G. Edwards(Executive Officer, Director)John Jacobi(Executive Officer)Sri Peruvemba(Executive Officer)Francois Jeanneau(Executive Officer, Director)
Avisi develops VisiPlate, a nanotechnology-enabled implant designed to lower intraocular pressure in patients with open-angle glaucoma.
Deep TechHealthtechMedical DevicesPhiladelphia, US
Rui Jing Jiang(Ms. Jiang is the Chief Executive Officer of the Issuer.)Paul Norris(Director)Brandon Kao(Director)Gary Pruden(Director)
BoardCatherine Mohr(Director)
BioLattice develops engineered cornea tissue as an alternative to donor cornea for patients with corneal blindness and those waiting for transplants.
BiotechHealthtechMedical DevicesPhiladelphia, US
Amelia Zellander(Executive Officer, Director)inLinda Alunkal(Executive Officer, Director)
BoardGregory Jackson(Director)
Therapeutics and diagnostics company
BiotechHummelstown, US
Stephen C. Rocamboli(Executive Officer, Director)Rifat Pamukcu(Director)Robert Towarnicki(Executive Officer, Director)Roger Sawhney(Director)
BoardTim Van Treuren(Director)John Fucci(Director)
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AI & Machine LearningDigital HealthHealthtech
Betsy Castillo(Head of Clinical Data Abstraction)in
ChromaTan develops biomanufacturing solutions that accelerate product development.
Advanced ManufacturingBiotechDeep TechLower Gwynedd, US
Steven Carpenter(Director)Andrew Zyndey(Director)Paul Silvis(Director)Oleg Shinkazh(Executive Officer, Director)
Forma Medical develops OptimalMTP, a minimally invasive surgical system for first metatarsophalangeal joint arthrodesis that combines plate-and-screw biomechanics with smaller incision techniques for foot surgeons.
HealthtechMedical Devices
Ilico Genetics develops a blood-based molecular test for the early detection of gastric cancer using methylated DNA markers, designed to identify disease years before traditional methods.
BiotechHealthtechMedical DevicesSantiago, CL
Immunomic Therapeutics develops nucleic acid immunotherapy platforms, particularly self-amplifying RNA and plasmid DNA vaccines, for cancer treatment, allergies, and animal health applications.
BiotechMedical DevicesRockville, US
Dong-Gun Kim(Executive Officer, Director)WILLIAM G. HEARL(Chief Executive Officer and Director)RONALD P. THIBOUTOT(Director)WILLIAM BARRY MCDONALD(Director)C. ERIC WINZER(Chief Financial Officer and Director)MICHAEL D. LACK(Director)
INDIGO Biosciences is a life sciences company led by professionals with expertise in life sciences, business management, and operations.
AI & Machine LearningBiotechDeep TechMedical DevicesState College, US
Dr. Jack Vanden HeuvelDr. Blake Peterson
Innsightech develops technology for disease diagnosis and management that translates laboratory innovations into clinical applications.
Digital HealthHealthtechMedical DevicesPittsburgh, US
Leanne Labriola(Executive Officer, Director, Promoter)Dipanjan Pan(Executive Officer)Gregory Jackson(Director)
Medical devices company; acquired by LumiThera.
Meduloc develops minimally invasive intramedullary implants for internal fixation of small and long-bone fractures.
BiotechMedical Devices
Sarah Sachinis(CEO and President)Michael Collins(Director)Benjamin Arnold(Director and Co-Founder)Brian Bowman(Co-Founder)
Micro Interventional Devices designs and manufactures medical devices for transcatheter cardiac repair procedures, enabling minimally invasive alternatives to open-heart surgery.
Deep TechHealthtechMedical DevicesNewtown, US
Michael Whitman(Founder, President, & CEO)Willard Hennemann(Executive Officer)
BoardMichael Gausling(Director)Jeffrey O'Donnell(Director)Christopher Thatcher(Director)Gerald Dorros(Director)
Discovery & development tools company; acquired by Kemet.
OK2StandUP develops smart activity monitoring systems with AI-based alerts for healthcare organizations to prevent falls and support caregiver awareness in patient care settings.
AI & Machine LearningHealthtechMedical DevicesPittsburgh, US
Eunice Yang, PhD(Founder and CEO)Eunice E. Yang(Executive Officer, Director)
Discovery & development tools company; acquired.
Healthcare IT company; acquired by Carta Healthcare.
SignatureDx develops noninvasive diagnostics using cell-free DNA (cfDNA) from liquid biopsy to identify "signatures" for early prediction and detection of disease.
BiotechDigital HealthMedical Devices
SOLUtion Medical is a specialty pharmaceutical company developing reconstitution drug-delivery products, including its dual-chamber TwistJECT prefilled syringe and auto-injector for treating adrenal crisis.
BiotechDigital HealthMedical Devices
Julia Anthony(Founder & CSO)
sovaSage develops technology that optimizes the CPAP mask-fitting process for sleep apnea patients.
AI & Machine LearningHealthtechMedical DevicesCentral City, US
William Kaigler(Executive Officer, Director)David Mawhinney(Director)Christian Kebekus(Executive Officer, Director)Julie Kaigler(Executive Officer)
Portfolio news
latest coverage across their companiesInnSight Technology, Inc. · manilatimes.net · Jul 30, 2026
Avisi Technologies · pci.upenn.edu · May 5, 2026
Frequently asked questions
- What stage does Life Sciences Greenhouse Investments invest at?
- Life Sciences Greenhouse Investments invests at the Pre-Seed, Seed, Series A, Series B stages.
- What is Life Sciences Greenhouse Investments's typical check size?
- Life Sciences Greenhouse Investments typically writes checks of $250K – $500K.
- What sectors does Life Sciences Greenhouse Investments focus on?
- Life Sciences Greenhouse Investments focuses on Biotech, Digital Health, Healthtech, Medical Devices.
- Where is Life Sciences Greenhouse Investments located?
- Life Sciences Greenhouse Investments is headquartered in Harrisburg, US.
- Does Life Sciences Greenhouse Investments lead rounds?
- Life Sciences Greenhouse Investments typically participates in rounds rather than leading them.
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