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Life Sciences Greenhouse Investments

Venture capital

Pennsylvania · Pre-Seed–Series B · 11 people tracked

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Investment thesis

The fund supports early-stage life sciences companies in Pennsylvania focused on drug discovery, diagnostics, medical devices, product commercialization, and IT-driven healthcare solutions. Beyond capital deployment, the firm provides operational support through connections to scientific and business experts to help portfolio companies navigate the unique challenges of developing healthcare innovations.

Source: firm website, verified Jul 21, 2026.

Stage
Pre-Seed–Series B
Check
$250K – $500K
HQ
Pennsylvania, US
Leads rounds
Follows
Instruments
Equity
Founded
2002
AUM
$44M
Tracked investments
22

Team · 11 people

from the firm's website
Michele Washko· President & CEO

Michele Washko brings over 25 years of experience in healthcare commercialization, finance, and innovation to her role leading LSG Investments.

Greg Jackson· Executive Vice President

Greg Jackson holds responsibility for identifying new investment opportunities, conducting due diligence, and mentoring and monitoring the performance of portfolio companies.

Haichen Yang· Vice President Clinical Research, Amicus Therapeutics
James V. Manser· Vice President, Global Government Relations, Johnson Controls International
Jeffrey Snellenburg· President, Pennsylvania Angel Network and Executive Director, Mid-Atlantic Angel Group
Jennifer Gilburg· Deputy Secretary, Technology and Entrepreneurship, PA Department of Community and Economic Development
Jon Morris· Vice President, IQVIA
Nishit Trivedi· Director, Life Sciences, Emerald Advisers
R. Sam Niedbala· CEO, CryoConcepts LP
Rebecca Stametz· Vice President Digital Transformation, Geisinger Steele Institute for Health Innovation
Stephanie Reisinger· Board Chair, Chief Commercial Officer, ConvergeEd LLC, and Commercialization Specialist, Total Experience Learning Institute, Alvernia University

What they invest in

from 14 of 22 portfolio companies

Healthtech ×11Medical Devices ×11AI & Machine Learning ×5Biotech ×5Deep Tech ×4Digital Health ×3Advanced Manufacturing ×1Data & Infrastructure ×1

HQs:United States×4Chile×1

Investments · 22 tracked

founders shown can be your intro path
Active Healthcare Data Abstractioncarta.healthcarein

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AI & Machine LearningDigital HealthHealthtech

Betsy Castillo(Head of Clinical Data Abstraction)

Avisi Technologiesavisitech.com

Avisi develops VisiPlate, a nanotechnology-enabled implant designed to lower intraocular pressure in patients with open-angle glaucoma. The company is conducting a pivotal clinical trial (SAPPHIRE) to evaluate the device as a minimally-invasive treatment option.

Deep TechHealthtechMedical Devices

Avisi Technologies
Biolattice Ophthalmics, Inc.biolatticetech.com

BioLattice develops engineered cornea tissue as an alternative to donor cornea for patients with corneal blindness and those waiting for transplants. The company focuses on tissue engineering to address the shortage of donor cornea supply in the global ophthalmology market.

BiotechHealthtechMedical DevicesPhiladelphia, US

Bobcat Bio
Chromatan, Inc.chromatan.com

ChromaTan develops biomanufacturing solutions that accelerate product development. The company focuses on manufacturing and biotech applications.

Advanced ManufacturingBiotechDeep Tech

Forma Medicalformamedical.com

Forma Medical develops OptimalMTP, a minimally invasive surgical system for first metatarsophalangeal joint arthrodesis that combines plate-and-screw biomechanics with smaller incision techniques for foot surgeons.

HealthtechMedical Devices

Ilico Geneticsilicogenetics.com

Ilico Genetics develops a blood-based molecular test for the early detection of gastric cancer using methylated DNA markers, designed to identify disease years before traditional methods. The company serves gastroenterologists and patients in the oncology diagnostics space, with a platform technology applicable to precision medicine and disease prevention.

BiotechHealthtechMedical DevicesSantiago, CL

Alejandro Corvalán(MD)inFernando Alarcon(MBA)inMaria J. Maturana(MSc)in

Immunomic Therapeuticsimmunomix.com

Immunomic Therapeutics develops nucleic acid immunotherapy platforms, particularly self-amplifying RNA and plasmid DNA vaccines, for cancer treatment, allergies, and animal health applications. The company's UNITE® platform leverages lysosomal targeting technology to generate immune responses against CMV, HPV, and other tumor-associated antigens across multiple cancer types and allergic conditions.

BiotechMedical Devices

Indigo Biosciencesindigobiosciences.com

INDIGO Biosciences is a life sciences company led by professionals with expertise in life sciences, business management, and operations.

AI & Machine LearningBiotechDeep TechMedical DevicesState College, US

Dr. Jack Vanden HeuvelDr. Blake Peterson

InnSight Technology, Inc.innsightech.com

Innsightech develops technology for disease diagnosis and management that translates laboratory innovations into clinical applications. The company serves ophthalmologists and clinical practitioners.

Digital HealthHealthtechMedical Devices

Intelligence Acquired by Carta Healthcare
Maculogixlumithera.com

Lumithera develops Valeda PBM, an FDA-authorized photobiomodulation light delivery system for treating dry age-related macular degeneration (AMD) to improve and maintain vision. The non-invasive treatment targets retinal cellular health by using specific light wavelengths to enhance mitochondrial energy production.

HealthtechMedical Devices

Micro Interventional Devicesmicrointerventional.com

Micro Interventional Devices designs and manufactures medical devices for transcatheter cardiac repair procedures, enabling minimally invasive alternatives to open-heart surgery. The company initially focuses on transcatheter mitral and tricuspid valve repair solutions.

Deep TechHealthtechMedical DevicesNewtown, US

Michael Whitman(Founder, President, & CEO)

Novasentiskemet.com
OK2STANDUPok2standup.com

OK2StandUP develops smart activity monitoring systems with AI-based alerts for healthcare organizations to prevent falls and support caregiver awareness in patient care settings. The solution serves hospitals, rehabilitation facilities, memory care facilities, and other care environments for older adults.

AI & Machine LearningHealthtechMedical DevicesPittsburgh, US

Eunice Yang, PhD(Founder and CEO)

Prosanosveradigm.com

Veradigm provides software solutions and data platform services for payers, providers, and life science companies in healthcare, combining clinical insights with research capabilities and provider network data.

AI & Machine LearningData & InfrastructureDigital HealthEnterprise SoftwareHealthtech

Realyze
Saladax Biomedical
Signature Diagnosticssignaturedx.com
SovaSagesovasage.com

sovaSage develops technology that optimizes the CPAP mask-fitting process for sleep apnea patients. The company works with sleep labs and medical equipment distributors to improve patient outcomes in the sleep apnea treatment sector.

AI & Machine LearningHealthtechMedical Devices

Frequently asked questions

What stage does Life Sciences Greenhouse Investments invest at?
Life Sciences Greenhouse Investments invests at the Pre-Seed, Seed, Series A, Series B stages.
What is Life Sciences Greenhouse Investments's typical check size?
Life Sciences Greenhouse Investments typically writes checks of $250K – $500K.
What sectors does Life Sciences Greenhouse Investments focus on?
Life Sciences Greenhouse Investments focuses on Biotech, Digital Health, Healthtech, Medical Devices.
Where is Life Sciences Greenhouse Investments located?
Life Sciences Greenhouse Investments is headquartered in Pennsylvania, US.
Does Life Sciences Greenhouse Investments lead rounds?
Life Sciences Greenhouse Investments typically participates in rounds rather than leading them.

Images

Life Sciences Greenhouse Investments photoLife Sciences Greenhouse Investments photo

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