Life Sciences Greenhouse Investments
Venture capitalHarrisburg · Pre-Seed–Series B · 12 people tracked
Investment thesis
LSGI aims to strengthen Pennsylvania's life sciences ecosystem and improve patient healthcare outcomes by providing early-stage capital that bridges the gap between pre-seed and Series B funding. It focuses on young Pennsylvania companies in drug discovery, diagnostics, medical devices, product commercialization, and IT-driven solutions to large-scale healthcare challenges. Beyond funding, LSGI offers operational expertise and access to a curated network of business and scientific advisors, drawing on deep understanding of both science and entrepreneurship to help early-stage companies navigate their challenges.
Source: firm website, verified Aug 11, 2026.
Team · 12 people
from the firm's website & curated
What they invest in
from 20 of 26 portfolio companiesMedical Devices ×16Healthtech ×13Biotech ×11Digital Health ×7AI & Machine Learning ×6Deep Tech ×4Advanced Manufacturing ×2Data & Infrastructure ×2
HQs:United States×13Chile×1
Who they back
founder profiles across 14 portfolio companiesFounding team size:solo founder×92 founders×5
Investments · 26 tracked
founders shown can be your intro pathBy year:2026 · 12025 · 12023 · 22022 · 22019 · 12018 · 18 dated
Avisi Technologies develops nanotechnology-enabled implantable devices to lower intraocular pressure in patients with open-angle glaucoma.
Deep TechHealthtechMedical DevicesPhiladelphia, US
Rui Jing Jiang(Ms. Jiang is the Chief Executive Officer of the Issuer.)inPaul Norris(Director)inBrandon Kao(Director)inGary Pruden(Director)in
BoardCatherine Mohr(Director)in
Co-investorsMedVenture Partners, Inc.Golden SeedsGood Growth Capital
BioLattice develops engineered cornea tissue as an alternative to donor cornea for patients with corneal blindness and those waiting for transplants.
BiotechHealthtechMedical DevicesPhiladelphia, US
Linda Alunkal(Executive Officer, Director)Amelia Zellander(Executive Officer, Director)in
BoardGregory Jackson(Director)
Co-investorsRobin Hood Ventures
Therapeutics and diagnostics company
BiotechHummelstown, US
Stephen C. Rocamboli(Executive Officer, Director)Rifat Pamukcu(Director)Robert Towarnicki(Executive Officer, Director)Roger Sawhney(Director)
BoardTim Van Treuren(Director)John Fucci(Director)in
Co-investorsBioAdvanceBios Partners
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AI & Machine LearningDigital HealthHealthtechPittsburgh, US
Gilan El Saadawi(Executive Officer, Director, Promoter)Betsy Castillo(Head of Clinical Data Abstraction)inMichael Finke(Director)Brenton Burns(Director)Scot Stevens(Director)Aaron Brauser(Executive Officer, Director, Promoter)
Co-investorsAsset Management CompanyFrist Cressey VenturesHealthy VenturesKatalyst VenturesKatalyst.VenturesMaC Venture Capital+3 more
ChromaTan develops biomanufacturing solutions that accelerate product development.
Advanced ManufacturingBiotechDeep TechLower Gwynedd, US
Oleg Shinkazh(Executive Officer, Director)Steven Carpenter(Director)Andrew Zyndey(Director)Paul Silvis(Director)
Forma Medical develops OptimalMTP, a minimally invasive surgical system for first metatarsophalangeal joint arthrodesis that combines plate-and-screw biomechanics with smaller incision techniques for foot surgeons.
HealthtechMedical Devices
James Gault(Founder)in
Co-investorsBroad Street Angels
Ilico Genetics develops a blood-based molecular test for the early detection of gastric cancer using methylated DNA markers, designed to identify disease years before traditional methods.
BiotechHealthtechMedical DevicesSantiago, CL
Immunomic Therapeutics develops nucleic acid immunotherapy platforms, particularly self-amplifying RNA and plasmid DNA vaccines, for cancer treatment, allergies, and animal health applications.
BiotechMedical DevicesRockville, US
WILLIAM G. HEARL(Chief Executive Officer and Director)William G Hearl(Chief Executive Officer, Director and Founder)Dong-Gun Kim(Executive Officer, Director)C. ERIC WINZER(Chief Financial Officer and Director)Bernard C Rudnick(Chief Financial Officer)Teri Heiland(Vice President of Research and Development)
Co-investorsKeiretsu Forum
INDIGO Biosciences is a life sciences company led by professionals with expertise in life sciences, business management, and operations.
AI & Machine LearningBiotechDeep TechMedical DevicesState College, US
Dr. Jack Vanden HeuvelDr. Blake Peterson
Co-investorsBroad Street AngelsiNetworksKeiretsu Capital
Innsightech develops technology for disease diagnosis and management that translates laboratory innovations into clinical applications.
Digital HealthHealthtechMedical DevicesPittsburgh, US
Leanne Labriola(Executive Officer, Director, Promoter)Dipanjan Pan(Executive Officer)
BoardGregory Jackson(Director)
Co-investorsRichard King Mellon Foundation
LumiThera develops the Valeda Light Delivery System, an FDA-authorized photobiomodulation (PBM) device that applies multiple light wavelengths to treat early and intermediate dry age-related macular degeneration (AMD).
BiotechHealthtechMedical DevicesPoulsbo, US
Tracy Puckett(Executive Officer)Clark Tedford(Executive Officer, Director)Scott Bradley(Executive Officer)Duane Morrison(Executive Officer)Cindy Croissant(Executive Officer)Ryan Montecucco(Executive Officer)
Co-investors3E Bioventures CapitalImagine VenturesKeiretsu Capital
Medical devices company; acquired by LumiThera.
Mediaspace is a digital agency that designs and builds custom Squarespace websites and provides SEO, digital marketing strategy, and digital advertising services.
AdTechAdvanced ManufacturingAI & Machine LearningData & InfrastructureDigital HealthEnterprise SoftwareHardwareHealthtechMarketing TechMedical DevicesSemiconductorsAtlanta, US
John G. Edwards(Executive Officer, Director)John Jacobi(Executive Officer)Sri Peruvemba(Executive Officer)Francois Jeanneau(Executive Officer, Director)Linda Ara(Executive Officer)Michael Vestel(Executive Officer)
Co-investors3E Bioventures CapitalKeiretsu ForumToba CapitalVivo Capital
Meduloc develops minimally invasive intramedullary implants for internal fixation of small and long-bone fractures.
BiotechMedical Devices
Benjamin Arnold(Director and Co-Founder)Brian Bowman(Co-Founder)Sarah Sachinis(CEO and President)
BoardMichael Collins(Director)
Co-investorsBroad Street Angels
Micro Interventional Devices designs and manufactures medical devices for transcatheter cardiac repair procedures, enabling minimally invasive alternatives to open-heart surgery.
Deep TechHealthtechMedical DevicesNewtown, US
Michael Whitman(Founder, President, & CEO)Willard Hennemann(Executive Officer)
BoardMichael Gausling(Director)Jeffrey O'Donnell(Director)Christopher Thatcher(Director)Gerald Dorros(Director)
Co-investorsOriginate Ventures
Discovery & development tools company; acquired by Kemet.
OK2StandUP develops smart activity monitoring systems with AI-based alerts for healthcare organizations to prevent falls and support caregiver awareness in patient care settings.
AI & Machine LearningHealthtechMedical DevicesPittsburgh, US
Eunice Yang, PhD(Founder and CEO)Eunice E. Yang(Executive Officer, Director)
Co-investorsScaleGood Fund LP (powered by TELUS)Beta Boom
Saladax Biomedical develops blood-level tests that help psychiatrists and oncologists determine correct individual drug dosages based on patient metabolism, supporting treatment decisions and reducing toxicity risk.
BiotechDigital HealthHealthtechMedical Devices
Co-investorsExcel Venture ManagementGolden Seeds
Signature Diagnostics develops noninvasive diagnostic and screening tools, including noninvasive prenatal screening (NIPS) and pharmacogenomic (PGx) testing, based on genomics research into women's reproductive and organ health.
BiotechDigital HealthFemTechMedical Devices
Dave Colaizzi(Co-founder & Chief Executive Officer)David Peters(Co-founder & Chief Science Officer)Tianjiao Chu(Chief Analytical Officer)
SOLUtion Medical is a specialty pharmaceutical company developing reconstitution drug-delivery products, including its dual-chamber TwistJECT prefilled syringe and auto-injector for treating adrenal crisis.
BiotechDigital HealthMedical Devices
Julia Anthony(Founder & CSO)in
Co-investorsBand of AngelsNextFab VenturesNW Angel
sovaSage develops technology that optimizes the CPAP mask-fitting process for sleep apnea patients.
AI & Machine LearningHealthtechMedical DevicesCentral City, US
William Kaigler(Executive Officer, Director)inDavid Mawhinney(Director)Christian Kebekus(Executive Officer, Director)Julie Kaigler(Executive Officer)
Co-investorsRiverfront Ventures, LLC
Veradigm provides solutions for healthcare stakeholders including payers, providers, and life science companies, leveraging its provider network to deliver data insights and research acceleration capabilities.
AI & Machine LearningData & InfrastructureDigital HealthHealthtechSaaS
Co-investorsEarl Grey Capital
Portfolio news
latest coverage across their companies
Veradigm · news.bloomberglaw.com · Aug 19, 2026
Signature Diagnostics · lsgpa.com · Jul 15, 2026
Avisi Technologies · pci.upenn.edu · May 5, 2026
BobcatBio · tinytechfund.com · Mar 13, 2025
Frequently asked questions
- How many investments has Life Sciences Greenhouse Investments made?
- Life Sciences Greenhouse Investments has 26 tracked investments, including 2 dated in the last 24 months.
- What stage does Life Sciences Greenhouse Investments invest at?
- Life Sciences Greenhouse Investments invests at the Pre-Seed, Seed, Series A, Series B stages.
- What is Life Sciences Greenhouse Investments's typical check size?
- Life Sciences Greenhouse Investments typically writes checks of $250K – $500K.
- What sectors does Life Sciences Greenhouse Investments focus on?
- Life Sciences Greenhouse Investments focuses on Biotech, Digital Health, Healthtech, Medical Devices.
- Where is Life Sciences Greenhouse Investments located?
- Life Sciences Greenhouse Investments is headquartered in Harrisburg, US.
- Does Life Sciences Greenhouse Investments lead rounds?
- Life Sciences Greenhouse Investments typically participates in rounds rather than leading them.
- Who does Life Sciences Greenhouse Investments co-invest with?
- Life Sciences Greenhouse Investments most often shares deals with Broad Street Angels, Keiretsu Forum, Asset Management Company, among 24 tracked co-investors.
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