National Institutes of Health (NIH) — Full Portfolio

Baltimore, US

ASAlexander Sulakvelidze(Executive Officer, Director)inJohn J Woloszyn(Executive Officer, Director)inMRMel Ruzicka(Executive Officer)

BoardGary Pasterneck(Director)Patrick Hervy(Director)

Intrinsic Life Sciences sells research kits, antibodies, and reagents for life sciences applications.

BiotechDeep TechDigital HealthMedical Devices

Intuitive Bio develops Colony Surveillance Assays (CSA), diagnostic kits for screening laboratory animal colonies for exposure to specific pathogens.

BiotechHealthtechMedical DevicesMiddleton, US

Shawn Guse(President and CEO)KLKimberly Luke(Vice President of Research and Development)inJBJohn Bart(Vice President of Operations)inJason R. Smith(Director)

BoardHarald Nordal(Director)Craig E Smith(Director)

Invenio develops rapid on-site tissue imaging systems combined with AI to improve cancer patient care.

AI & Machine LearningBiotechDeep TechMedical DevicesSanta Clara, US

JTJay Trautman(President & CEO, Co-Founder)inCFChris Freudiger(Chief Technology Officer, Co-Founder)inChristian Freudiger(Director)inXXXiaoliang Xie(Director)

BoardDCDoug Crawford(Director)in

Co-investorsBEBerkeley CatalystMIMission Bay CapitalMIMission Biocapital

InvivoSciences is a biotechnology company led by a team with deep expertise in biomedical engineering, pharmaceutical development, and biophysics, serving the pharmaceutical and biotech industries.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesMadison, US

Ayla Annac(Co-founder & CEO)Annac(Co-founder, CEO, President & Board Member)Tetsuro Wakatsuki(Co-founder, Chief Scientific Officer, Patent Holder, Board Member & Scientific Advisory Board Member)Elliot Elson(Co-founder, Patent Holder, Chief Scientific Board Member, Board Member & Scientific Consultant)

Io Therapeutics develops small molecule retinoid drugs, including IRX4204 and IRX5183, as potential treatments for oncology, neurologic, autoimmune, and dermatologic conditions such as psoriasis.

BiotechHealthtechSpring, US

Roshantha A. Chandraratna(Executive Officer, Director)Rosh Chandraratna(Co-founder, initial President & Chief Scientific Officer)Martin Sanders, M.D.(Executive Chairman and CEO, co-founder)Vidyasagar (Sagar) Vuligonda, Ph.D.(Director and Chief Science Officer, co-founder)Rosh Chandraratna, Ph.D(Co-founder and initial President and Chief Scientific Officer)Sharon Lew(Executive Officer)

IonOptix manufactures systems for fluorescent ion quantitation and muscle mechanics measurements used in preclinical cardiac and cellular research.

BiotechDeep TechHardwareHealthtechMedical DevicesWestwood, US

Douglas Tillotson(Founder)

iotaMotion develops robotic systems for cochlear implant surgery, assisting otolaryngologists in achieving precision beyond human capability.

HealthtechMedical DevicesRoboticsSt. Paul, US

Marlan Hansen, MD(Executive Officer, Director)MHMarlan Hansen(Executive Officer, Director)Christopher Kaufmann(Executive Officer, Director)MHMarlan Hansen, MD, FACS(Co-founder & Chief Medical Officer)Michael Lobinsky(Executive Officer, Director)

BoardWWWayne Wallace(Director)

Co-investorsISISA VenturesMUMutual Capital PartnersNENext Level Ventures

Voxello develops the noddle, a plug-and-play system that detects patients' small voluntary gestures via sensors so impaired or disabled patients can summon caregivers and operate nurse call systems and speech-generating devices.

Digital HealthHardwareHealthtechMedical DevicesIowa, US

Richard Hurtig(Chief Scientific Officer)Vince HahnBen BerkowitzZihan ZhuBlake Martinson

IQ Proteomics is a contract research organization (CRO) providing quantitative, proteome-wide mass spectrometry services, including drug target identification, chemoproteomics, protein-protein interaction profiling, and custom targeted assays.

BiotechDeep TechHealthtechBoston, US

Decode operates a platform that unifies multiomic, clinical, and real-world data with automated analytics and expert configuration to deliver validated R&D findings for precision medicine.

AI & Machine LearningBiotechDigital HealthNashville, US

Charles Floyd Spurlock III(Executive Officer, Director)JBJulia B. Polk(Executive Officer, Director)in

Iridia develops Molecular Avatar Technology that embeds unalterable molecular identities and custom data (text, image, audio, or video) into physical products and materials such as paints, coatings, plastics, and liquids.

BiotechDeep TechNew Materials

Co-investorsATATEM Capital FundCOConnecticut InnovationsDUDuke Capital PartnersLILifeSci Venture PartnersLOLongley CapitalWEWestern Digital Capital+1 more

Trifoia designs and delivers online training and educational content focused on knowledge-building and professional development across various sectors.

EdTechEnterprise SoftwareFuture of WorkMedia & EntertainmentSaaSEugene, US

Adam Wendt(CEO)Mark Davis(CTO)

Co-investorsTRTribes Ventures

Gizmos Investigations is an interactive online platform that places students in the role of STEM professionals solving real-world problems through guided inquiry activities.

AdTechAI & Machine LearningEdTech

Isabl develops whole genome and transcriptome sequencing technology for cancer diagnosis, delivering comprehensive genomic profiling and treatment options to physicians and research teams.

BiotechDigital HealthHealthtechMedical DevicesNew York City, US

JMJuan Medina(Founder)inAKAndrew Kung(Founder)inEPElli Papaemmanuil(Founder)in

Co-investorsY Y CombinatorBOBoxOne VenturesTWTwo Sigma VenturesEVEvolution VC PartnersSASand Hill AngelsAMAmino Capital+1 more

Isoformix develops protein isoform assays and biomarker discovery services, with a focus on identifying novel therapeutic targets for Alzheimer's disease.

AI & Machine LearningBiotechDeep TechHealthtechMedical Devices

Dr. Nedelkov(Founder & CEO)

Isola Therapeutics develops endoluminal drug delivery solutions for treating life-threatening diseases through proprietary systems designed for pulmonary and gastrointestinal applications.

BiotechDeep TechMedical Devices

Isolere Bio develops affinity-based reagents and purification platforms for concentrating and purifying viral vectors used in gene therapy, including adeno-associated viruses and lentiviruses.

Advanced ManufacturingBiotechDeep TechNew MaterialsResearch Triangle Park, US

Michael LaBreck(Co-founder)Michael Dzuricky(Director of Advanced R&D)

Co-investorsNONorthpond Ventures

IsoPlexis (now part of Bruker Cellular Analysis) provides single-cell functional profiling technology used to discover therapeutic antibodies, interrogate T cells for novel cell therapies, and accelerate cell line development.

BiotechDeep TechMedical DevicesNew Haven, US

Rong Fan(Director)Sean McKay(Executive Officer, Director)Sean Mackay(Executive Officer, Director)

BoardDaniel Wagner(Director)JCJohn Conley(Director)inGregory Ho(Director)

Co-investorsCOConnecticut InnovationsALAlly Bridge GroupIRIronwood CapitalNONorthpond VenturesSPSpring Mountain Capital

LifeLoop is a software platform for senior living communities that integrates with electronic health records to streamline administrative workflows and enable resident engagement and enrichment activities.

Digital HealthHealthtechSaaSWellness & Fitness

iVeena Delivery Systems is a clinical-stage ophthalmology company developing pharmacologic eye-drop therapies for refractive eye diseases, including IVMED-80 for keratoconus and IVMED-85 for pediatric myopia.

BiotechHealthtechMedical DevicesSalt Lake City, US

BABalamurali Ambati(Executive Officer, Director)Gerald Simmons(Executive Officer)NWNed Weinshenker(Executive Officer, Director)in

BoardDavid Robinson(Director)James Jensen(Director)Greg Jones(Director)

BiotechCranbury, US

Bo Liang(Executive Officer, Director)Houman Hemmati(Executive Officer, Director)Wei Wang(Executive Officer, Director)John J Baldwin(Director)Tao Du(Director)

BoardQi Zhu(Director)

Co-investorsBIBioAdvance

IVOS Medical is developing the BOSS, a single-use, custom-molded video laryngoscope sleeve that provides continuous suction and independent oxygen delivery to keep the camera view clear during difficult intubations.

HardwareHealthtechMedical Devices

Gabriel Punsalan(Founder & CEO)

iXpressGenes operates a CLIA-certified, CAP-accredited molecular diagnostics laboratory that provides genetic testing and analysis services.

BiotechDigital HealthMedical DevicesHuntsville, US

John Schmitt(Executive Officer, Director)inJNJoseph Ng(Executive Officer, Director)

BoardPeggy Sammon(Director)Barbara Fisk(Director)

Co-investorsGEgener8tor

Jacaranda Bio is a preclinical-stage biotech company developing therapeutics to restore hearing loss by re-establishing cellular homeostasis, with a focus on the TMTC4 gene linked to progressive post-natal hearing loss.

BiotechDeep TechHealthtechLongevityMedical DevicesSan Francisco, US

Jan Biotech develops molecular diagnostics that directly detect RNA at the cellular level using its patented RNAamp chemical amplification technology, applied to quantifying latent HIV reservoir cells and discriminating Covid-19 variants.

BiotechHealthtechMedical Devices

JangoBio is a biotechnology company developing regenerative stem cell therapies aimed at aging and age-related diseases by restoring sex hormone balance.

BiotechHealthtechLongevityFitchburg, US

Robert Cramer(Director)William Kohl(Executive Officer, Director)Victor Mohoney(Director)Richard Bowen(Director)Craig S. Atwood(Executive Officer, Director, Promoter)

JANUS Research is a defense-focused organization providing research, analysis, and solutions for government customers.

AI & Machine LearningDeep TechDefense TechSector AgnosticSpace Tech

John Dewey(Chief Executive Officer)Curtis Sumner(Chief Operating Officer)

Javelin Bio offers a microphysiological system platform that simulates human liver biology using primary human cells to provide drug and disease response data for preclinical research.

AI & Machine LearningBiotechDeep TechHealthtechMedical Devices

Murat Cirit(CEO, Cofounder)Emily Geishecker(VP of Operations, Cofounder)

JBS Science develops liquid biopsy technology that detects circulating cell-free DNA in urine for cancer screening and management.

BiotechDigital HealthMedical Devices

Jericho Sciences develops small molecule therapeutics targeting chronic viral infections and emerging viruses, with a focus on achieving long-term remission through reduction of persistent viral sources.

BiotechHealthtechMedical DevicesTampa, US

Dr. Heidi Kay(Founder and CEO)inDr. Haitao GuoinDr. Deanna KulpainDr. Marco SchitoinDr. Esther AlegriainDr. Joe Sebastianin

Jointechlabs develops point-of-care regenerative medicine devices, including the FDA-cleared MiniTC for processing autologous fat into microfat and the CE-marked Mini-Stem System for SVF processing.

BiotechHealthtechMedical DevicesBrandon, FL, US

NPNishit Pancholi(Co-Founder, COO, Chief Medical Officer)inNKNathan Katz(Founder)inDr. Nathan Katz, PhD, ELD (ABB)(Co-Founder, CEO, Chief Scientific Officer)

Co-investorsEXExpert DOJO

Jorvec develops electrophysiology instruments, including a visual stimulator, desktop station, and animal stage, for vision and retinal research applications.

BiotechHardwareMedical Devices

Joyuus is a digital health platform for women that provides evidence-based information and personalized guidance, starting with postpartum care, to help mothers distinguish normal symptoms from warning signs and connect to relevant care.

Digital HealthFemTechMental Health

Lisa Marceau(Founder)Madison Soucie(CTO)

Juvena Therapeutics develops biologics derived from human secreted proteins to treat aging-related diseases, using AI-enabled drug discovery to identify tissue-restorative therapeutics for muscle and metabolic disorders.

AI & Machine LearningBiotechLongevityMedical DevicesRedwood City, US

JOJeremy O'Connell, PhD(Chief Scientific Officer and Co-Founder)HYHanadie Yousef, PhD(Co-Founder, Director and Executive Advisor)JOJeremy O'Connell(Director)inDHDr. Hanadie Yousef(Founder)inJulie Anne Smith(Chief Executive Officer and Director)

BoardBHBen Hemani(Director)in

Co-investorsALAlumni VenturesBABascom VenturesBIBison VenturesCOCompoundHAHarmonix FundHOHorizons Ventures+5 more

K Medical is a healthcare startup developing simple, effective medical solutions, with a current focus on preventing bedsores (pressure ulcers).

HardwareHealthtechMedical DevicesCleveland, US

David Kay(Director)William Fuller(Executive Officer)

K&A Wireless is a company presenting itself as a provider of Internet of Things (IoT) technology.

IoT

KAER develops aerosolization systems (AeroPulsR for aqueous aerosols and SUPRAER for dry aerosols) that generate high-concentration respirable aerosols from liquid APIs, biologics, and advanced formulations for delivery to pediatric and adult patients in critical, acute, chronic, and home respiratory care.

BiotechHealthtechMedical Devices

Kairos Research conducts applied research on human-AI collaboration and cognitive systems for clients in commercial, academic, and government sectors.

AI & Machine LearningDeep TechDefense TechDayton, US

Dr. Brandon (Brad) Minnery(Founder and CEO)Ebi Maki(Co-founder and COO)

ILMUTOTO is a licensed online gaming platform serving Indonesian players with various popular game types, daily bonuses, and 24/7 customer support.

Digital HealthGamingHealthtechWellness & Fitness

KamTek is a biotechnology company providing sample storage, cryopreservation, and logistics services for biomedical research institutions, government labs, and biopharma companies.

BiotechEnterprise SoftwareHealthtechLogistics & Supply ChainFrederick, US

Karamedica develops chitosan-based biomedical technologies for therapeutic applications, particularly focused on Alzheimer's disease and drug delivery systems.

AI & Machine LearningBiotechHealthtechMedical DevicesNew Materials

Andrew Crofton(Chief Executive Officer)Samuel Hudson(Chief Scientific Officer)Taub T Swartz(Chief Financial Officer)

Karyopharm is a pharmaceutical company developing drugs based on its SINE (Selective Inhibitor of Nuclear Export) technology, with medicines targeting cancers including multiple myeloma and diffuse large B-cell lymphoma.

BiotechHealthtechNewton, US

SPStuart Poulton(Executive Officer)inMichael Mano(Executive Officer)inRRReshma Rangwala(Executive Officer)inRPRichard Paulson(CEO)inStephen Mitchener(Executive Officer)inMichael Mason(Executive Officer)in

Co-investorsAVAvoro Capital AdvisorsFOForesite CapitalHEHEALTHCARE ROYALTY PARTNERSRARA Capital

KatheraBio develops antifungal therapies targeting cellular enzymes involved in fungal growth and pathogenicity, with applications as monotherapies or combination treatments for drug-resistant fungal infections.

BiotechDeep TechHealthtechMedical DevicesUnion, US

Stephen Parent

KDHRC provides research and evaluation services for health and behavioral interventions, including formative research, program evaluation, and implementation support.

Data & InfrastructureDigital HealthHealthtechImpact & Social GoodAtlanta, US

Keona Health provides a healthcare contact center platform that guides call center agents and nurses through clinical pathways and handles routine patient requests across phone, SMS/chat, and web to schedule appointments and manage care coordination.

AI & Machine LearningDigital HealthHealthtechChapel Hill, US

OOOAKKAR OAKKAR(Executive Officer, Director)inSDSTEPHEN DEAN(Executive Officer)inJKJimmy Kaanapu(Founder)inJIMMY KAANAPU(Executive Officer)in

BoardBRUCE THOMPSON(Director)

Co-investorsIDIDEA NCRIRiverside Acceleration CapitalSASaaS CapitalTHThe Riverside Company

Kephera develops diagnostic technologies and products targeting point-of-care testing, third-party assay development, and specific disease markets including Lyme disease and neuroinfectious diseases.

BiotechDigital HealthHealthtechMedical DevicesFramingham, US

Andrew Levin, Ph.D.(Chief Executive Officer / Chief Scientific Officer)

KeraNetics develops keratin-based medical products for wound care, with its lead product KeraStat Cream, an FDA-cleared prescription treatment for managing radiation dermatitis in cancer patients undergoing radiotherapy.

BiotechHealthtechMedical DevicesWinston-Salem, US

MEMark E Van Dyke(Executive Officer, Director)Charles W Johnson(Executive Officer, Director, Promoter)KDKim D Westmoreland(Executive Officer, Director, Promoter)in

BoardDonald E Flow(Director)Graeme M Keith, Jr.(Director)Graeme M Keith(Director)

Kestrel Labs develops software that translates building code into machine-executable logic and runs compliance checks directly within BIM models, integrated into tools like Autodesk Revit.

AI & Machine LearningConstruction TechDeveloper ToolsPropTechSaaSDenver, US

MPMarian Pulford(Co-founder)inBBrian(VP of Engineering)in

Co-investorsFIFirstMile VenturesNENew Stack VenturesTETechstarsAVAvesta FundDEDenver Ventures

Key Tech designs and develops medical, industrial, and consumer products using advanced technologies including sensors, wireless systems, ultrasound, microfluidics, optics, and robotics.

Advanced ManufacturingDigital HealthHardwareHealthtechMedical DevicesSaaSBaltimore, US

Jenny(Founder and former CEO)Scott(Co-founder)

BioDive is an immersive educational VR experience that teaches marine biology and ecosystem science through interactive investigations of venomous marine snails.

EdTechGaming

ChristopherCorinneJohnNoelleOscarAlyssa

BiotechSeattle, US

Shawn Iadonato(Executive Officer, Director)inRobert Hedequist(Executive Officer)Pauline Kenny(Executive Officer)inCharles Magness(Director)

Co-investorsKEKeiretsu ForumPFPfizer Venture InvestmentsTSTSVCWEWellcome Trust

Kinetic River provides nanoparticle analysis services, characterizing exosomes and other nanoparticles in customer-submitted samples and delivering detailed reports.

BiotechDeep TechHealthtech

Dr. Vacca(Founder)

BioKinetiq develops next-generation replacement enzymes aimed at reducing the treatment burden for people with rare diseases.

BiotechHealthtech

Kinto provides personal care coaching to family caregivers looking after a loved one with dementia, pairing them with a designated Care Coach and offering a curriculum with personalized action plans.

Digital HealthHealthtechWellness & Fitness

Co-investorsTHThe E14 FundBRBrevan Howard Digital

Kiromic BioPharma was a clinical-stage biotherapeutics company using an AI-driven platform to develop allogeneic Gamma Delta T-cell immunotherapies for solid tumors, including lead candidate Deltacel-01 for lung cancer.

Co-investorsSOSofinnova Ventures

Kitware provides custom software solutions and advanced technical computing based on open source platforms, serving government agencies, commercial organizations, and research institutions.

AI & Machine LearningDeep TechDeveloper ToolsEnterprise SoftwareClifton Park, US

Lisa AvilaBill HoffmanWill SchroederKen MartinCharles Law

KIYATEC develops 3D Predict, a tumor-specific testing platform that uses patient-derived tumor cells to predict how individual cancers respond to therapies.

BiotechDigital HealthHealthtechMedical DevicesGreenville, US

Matthew Gevaert(Director)EPEric Perreault(Executive Officer, Director)inMRMelissa Rayner(Executive Officer)inSIScott Isacksen(Executive Officer)inDEDavid E Orr(Chief Operating Officer)in

BoardCBChristopher Brotherton(Director)

Co-investorsATAtlanta Technology AngelsSESeae VenturesVEVentureSouth

Klein Buendel is a women-owned research and communication firm that develops health communication materials and conducts multimedia production and research.

Digital HealthHealthtechImpact & Social GoodLakewood, US

Mary K. Buller

A website publishing product reviews and testing write-ups for home and garden items such as insect trap coatings.

Media & Entertainment

Kognito develops evidence-based digital learning simulations that teach mental health and well-being skills through interactive role-play conversations with virtual characters.

Digital HealthEdTechHealthtechMental Health

Kromatid provides single-cell structural genomic analysis tools for cell and gene therapy companies, enabling assessment of genomic integrity and identification of complex structural rearrangements during therapy development.

AI & Machine LearningBiotechDeep TechMedical DevicesLongmont, US

Andrew Jost(Executive Officer)James Chomas(Executive Officer, Director)Christopher Tompkins(Executive Officer, Director)Susan Bailey(Executive Officer)Joel Bedford(Director)

BoardTerry Opgenorth(Director)

Active seed-stage healthcare company

Eugene, US

Nicholas Allen(Chief Executive Officer)Phillip Scripa(Chief Financial Officer and Secretary)William Shortt(Chief Operating Officer)Jan Hardorp(Director)in

Co-investorsBIBIP VenturesJLJLSPAPalo Santo VCREre.Mind Capital

Kuda Therapeutics develops novel cancer therapies targeting hypoxia and HIF signaling pathways.

BiotechHealthtechLongevityMedical DevicesSalt Lake City, US

Dr. Mei Yee Koh(Founder/Director and Chief Executive Officer)Mr. Travis Ehlinger(co-Founder/Director and Chief Financial Officer)

BiotechSeattle, US

Jonathan Himmelfarb(Executive Officer, Director)Buddy Ratner(Executive Officer, Director)

Kypha develops clinical diagnostic tests for immune system biomarkers, particularly complement activity markers, and provides solutions for real-time immune insights across therapeutic areas.

BiotechDeep TechHealthtechMedical DevicesSt. Louis, US

NSNick Staten(Executive Officer)inT. Scott Glover(Executive Officer)inPaul K. Olson(Executive Officer, Director)

BoardDSDavid Smoller(Director)inJames D. Marselis(Director)PRPeter Reinecke(Director)in

Co-investorsBIBioGenerator VenturesMIMissouri Technology CorporationARArsenalSESerra Ventures

Kytopen develops non-viral gene delivery technology called Flowfect that combines fluid flow with electric fields to deliver payloads such as mRNA, DNA, and CRISPR Cas9 RNP into cells for high-throughput transfection.

BiotechDeep TechHardwareCambridge, US

CBCullen Buie(Founder; Board Observer)inPGPaulo Garcia(Founder)inMCMichael Chiu(Chief Executive Officer)in

BoardPMPaxton Major(Director)inADAnn DeWitt(Director)inPaul Wotton(Director)

Co-investorsBABantam GroupHOHorizons VenturesMAMassVenturesSESelvedge VentureTBTBD AngelsTETelegraph Hill Partners+3 more

Lab11 Therapeutics develops host-directed therapeutics using small molecules and mRNA approaches to modulate human immune response against viral infections, targeting prevention and treatment of diseases including influenza and COVID-19.

BiotechDigital HealthHealthtechMedical DevicesNew York, US

LabSys manufactures electrochemical gas sensors using proprietary microfabrication processes for applications spanning industrial safety, medical breath analysis, transportation, environmental monitoring, agriculture, and wearables.

Deep TechHardwareIoT

FemTechHealthtechWellness & FitnessSanta Monica, US

SCStephanie Canale(Executive Officer, Director)inMelissa Gee(Director)Eric Canale(Executive Officer, Director)

Co-investorsTETechstars

LambdaVision develops a protein-based artificial retina designed to restore vision for patients blinded by advanced retinal degenerative diseases such as retinitis pigmentosa and age-related macular degeneration.

BiotechMedical DevicesSpace Tech

Robert R. Birge(Founder)NLNicole L. Wagner(President and Chief Executive Officer)inJAJordan A. Greco(Chief Scientific Officer)in

Co-investorsAUAurelia FoundryCOConnecticut InnovationsSESeraphim SpaceSESeven Seven SixBABand of AngelsE2E2MC Ventures

LapIQ develops proprietary biodegradable platform solutions for surgical applications, including laparoscopic trocar port closure and repair of congenital abdominal wall defects.

BiotechHealthtechMedical Devices

LASE Innovation provides single-cell tracking and barcoding technology that captures time-dimension data to train AI/ML models for biological research.

AI & Machine LearningBiotechDeep TechHardwareBoston, US

DSDr. Sheldon J.J. Kwok(Founder)Dr. Seok-Hyun (Andy) Yun(Founder)

Co-investorsKAKakao VenturesTATaihill VentureOTOtium Capital

Lassogen engineers lasso peptides — structurally unique 3D scaffolds — into therapeutics it calls Lassotides, designed to combine the strengths of antibodies and small molecules.

AI & Machine LearningBiotechSan Diego, US

Mark J Burk(Executive Officer)in

Co-investorsBEBetter Ventures Central LlcFIFirst In VenturesPLPlayground Global

Goleta, US

Dave Paden(Principal Mechanical Engineer - Co-Founder)inBradley Paden(Director)NSNazeeh Shaheen(Chief Operations Officer)inJohn Reardon(Vice President, Engineering and Programs)CMCyrus Morici(Chief Financial Officer)inMichael Ricci(Chief Technology Officer)

LayerBio develops ophthalmology therapies, including OcuRing, a bioerodible sustained-release drug delivery technology designed to work with standard intraocular lenses (IOLs) used in cataract surgery.

BiotechHealthtechMedical Devices

Lazarus 3D develops patented soft-tissue 3D printing technology that produces anatomically accurate, life-like models which can be cut, sutured, and scoped.

BiotechHouston, US

JEJACQUES ERIC ZANEVELD(Executive Officer, Director)Dr. Jaques Zaneveld, Ph.D(Founder & CEO)

BoardRANDY BERNDT(Director)RICHARD HIGGINS(Director)

Instem is a SaaS platform provider offering integrated solutions for research organizations across discovery, study management, regulatory submission, and clinical trial analytics in the life sciences sector.

AI & Machine LearningBiotechData & InfrastructureDeep TechHealthtechSaaS

LEAH Labs engineers gene-edited CAR-T cell therapies to treat cancer in pet dogs, with the goal of generating translational insights for human cancer therapy.

AI & Machine LearningBiotechHealthtechMedical DevicesMinneapolis, US

WWWesley Wierson(Founder & CEO)inStephen C. Ekker(Scientific Founder & Board Director)SSSaad S. Kenderian(Scientific Founder)JPJonathan P. Mochel(Scientific Founder)SSSaad S. Kenderian, MB/ChB(Scientific Founder)JPJonathan P. Mochel, PhD/DECVPT(Scientific Founder)

Co-investorsGRGROOVE CAPITALSOSoutheast Minnesota Capital FundY Y CombinatorAGAg Startup Engine SeedWEWefunder

Lebrun Labs is a toxicology company that develops and commercializes nonanimal, human-relevant toxicity tests, offering contract testing, test kit manufacturing, and licensing across ocular, dermal, and systemic organ endpoints.

BiotechHealthtechNew MaterialsAnaheim, US

Led Radiofluidics designs photoredox radiolabeling reactors for pharmaceutical research and development, enabling direct radiolabeling of active pharmaceutical ingredients using LED light sources and patented photoredox reaction methodologies.

BiotechDeep TechHardwareMedical DevicesChapel Hill, US

David Nicewicz(Co-founder)Zibo Li(Co-founder)

Lena Bio develops bioengineered products for organ and cell culture research, including perfused organ panels, cell culture scaffolds, and specialized research tools for life science laboratories.

BiotechDeep TechDigital HealthHealthtechMedical DevicesAtlanta, US

Leuko develops a noninvasive white blood cell monitor to track neutropenia risk in cancer patients and others undergoing treatment.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesBoston, US

CCCarlos Castro Gonzalez(Chief Executive Officer)inIBIan Butterworth(Chief Technology Officer)inABAurelien Bourquard(Chief Data Scientist)inAlvaro Sanchez-Ferro(Chief Medical Officer)inCCCarlos Castro-Gonzalez(Founder)inPHPaul Hartung(Director)in

Co-investorsGOGood Growth CapitalDODorm RoomMAMassVenturesNINina CapitalIAIAG Capital Partners

Lgenia is a drug discovery company focused on developing new medicines for tuberculosis, malaria, Alzheimer's disease, and non-hormonal contraceptives, with a mission to make treatments accessible and affordable globally.

BiotechDigital HealthFemTechHealthtech

Dr. Philip A. Hipskind(Chief Executive Officer & Chief Scientific Officer)

LI-COR builds measurement and monitoring instruments — including gas analyzers, data loggers, weather stations, and software — for studying carbon flux, greenhouse gas emissions, water quality, soil conditions, and plant health across soil, water, and atmospheric ecosystems.

AgTechCleantechClimate TechHardware

TRThomas Reslewicin

Co-investorsBABattery Ventures

LTI develops prosthetic and orthotic technologies and conducts research to improve outcomes for individuals with limb loss.

Deep TechDefense TechHealthtechMedical DevicesHolliston, US

LifeBio offers a reminiscence therapy platform and mobile app that records people's life stories, preferences, and care preferences in their own voice, then turns them into Life Story Books, care planning Snapshots, and Action Plans stored in HIPAA-compliant cloud storage.

Digital HealthHealthtechWellness & Fitness

Beth Sanders(Founder)

LifeCanvas provides whole tissue processing, light sheet imaging, and analysis solutions for biomedical researchers.

AI & Machine LearningBiotechDeep TechHardwareMedical Devices

Kwanghun Chung(Founder)

LifeGene BioMarks develops DNA-based tools for early cancer detection, enabling individuals and communities to monitor their health proactively.

BiotechDigital HealthHealthtechMedical DevicesBaltimore, US

Albert G. Thomas(Chief Clinical Officer)David Sidransky, MD(Chairman of the Board)Rafael Guerrero-Preston DrPH, MPH(Chief Scientific Officer)Albert G. Thomas, MD(Clinical Operations Officer)David Sidransky(Chairman of the Board)Rafael Guerrero-Preston(Chief Scientific Officer)

Lifetime Omics is a biotech and health-informatics company that builds infrastructure for training clinical AI systems on quality-controlled, integrated data from electronic health records, multi-omics, and imaging while protecting patient privacy.

AI & Machine LearningBiotechDigital Health

LigandomicsRx develops technology to accelerate the discovery of drug targets for pharmaceutical research.

AI & Machine LearningBiotechDeep Tech

Lightswitch Bio develops photoactivated chemotherapy treatments using laser-precision technologies to reduce side effects for cancer patients.

BiotechDeep TechHealthtechMedical DevicesRichmond, US

Digital HealthMedical Devices

Co-investorsBOBoulder VenturesENEntrada Ventures

Lighthaus creates immersive virtual reality experiences designed to enhance science education and medical training.

EdTechGamingHardwareHealthtechMedical Devices

Lightning Packs develops high-performance equipment using biomechanics research focused on muscle efficiency and energy optimization.

CleantechConsumerDefense TechHardwarePhiladelphia, US

Dr. Lawrence Rome(Founder and Chief Scientific Officer)Sean McIntosh(Director of Engineering)Shawn Carmody(Product Development Manager)

LighTopTech develops optical imaging instruments for industrial non-destructive testing and medical applications including surgical guidance.

Advanced ManufacturingDeep TechHardwareHealthtechMedical Devices

Lightpoint Medical develops surgical guidance systems for intracavity radio-guided surgery, used in minimally-invasive and robot-assisted procedures such as prostate cancer surgery.

HardwareHealthtechMedical DevicesRobotics

Co-investorsANAnjostKEKeiretsu ForumVEVenture Founders

LightSeed is a clinical-stage biotech company focused on light-activated gene therapy for cancer and cardiovascular disease.

BiotechDigital HealthHealthtechMedical DevicesPhiladelphia, US

Dr. Richard Pestell(Founder)

Liiingo is a link-management platform offering bio link pages, shortened URLs, QR code generation, static site hosting, vCards, file transfer, and built-in analytics.

Marketing TechSaaS

Likarda develops a hydrogel encapsulation platform that delivers cell therapies, biologics, and small molecules with customizable release profiles and protection from immune attack.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesLawrence, US

Lisa Stehno-Bittel(Founder, PhD)

Limber Prosthetics builds 3D-printed prosthetic devices and a digital scan-design-fabricate workflow for orthotics and prosthetics (O&P) clinicians.

HardwareHealthtechMedical DevicesSan Diego, US

Luca DeVivo Nicoloso(Executive Officer, Director)inJSJoshua Stephen Pelz(Chief Executive Officer, Co-founder)HBHerb Barrack(Chief Clinical Officer, Co-founder)inLuca De Vivo Nicoloso(Co-founder, Board Advisor)inHerbert Joseph Barrack(Executive Officer, Director)WWWalker White(Executive Officer)in

Develops software to treat adolescent mental health.

Co-investorsADAdventure FundJAJAZZ Venture PartnersPRPresence CapitalSTStorm Ventures

LinAmp Technologies designs and manufactures standardized power amplifier modules for cellular base stations operating in 2G, 3G, and 4G networks, serving commercial, medical, and military markets globally.

Deep TechDefense TechHardwareLaguna Hills, US

Cen4ard offers educational and activity kits, reading materials, and training resources, primarily serving individuals with dementia and their caregivers.

Digital HealthEdTechHealthtechMedical DevicesMental Health

Dr. Cameron Camp

Linshom Medical manufactures a wearable, FDA-cleared respiratory monitoring device that provides operating room quality respiratory data at the patient bedside, designed to detect early signs of respiratory problems and reduce adverse events in post-surgical and other patient care settings.

HealthtechMedical Devices

Co-investorsMAMaryland TEDCOTETEDCO

Liquid Gold Concept is a health and wellness magazine that publishes research-based content on preventive healthcare, nutrition, fitness, and wellness trends for general readers.

Media & EntertainmentWellness & Fitness

Dave Smith(Founder)

Co-investorsRHRhapsody Venture PartnersRORoadmap Capital Inc.STStruck CapitalSTStructure Capital

Litmus Health provides infrastructure for capturing, monitoring, and analyzing wearable and sensor data in clinical trials and observational studies.

AI & Machine LearningData & InfrastructureDigital HealthHealthtechMedical Devices

Daphne Kis(Co-Founder, Business and Operations)Sam Volchenboum(Co-Founder, Chief Medical Officer)Josh Jones-Dilworth(Co-Founder, Sales and Marketing)Dominiek Ter Heide(Chief Technology Officer)

Little Sparrows Technologies develops medical devices for newborn care, including the bili-hut portable phototherapy device for treating neonatal jaundice and the bili-ruler jaundice screening tool.

Winchester, US

DBDONNA BREZINSKI(Founder, CEO)inGARY GILBERT(Founder, COO)

BoardDOUGLAS TRECO(Director)GEORGIA MCGAUGHEY NICHOLLS(Director)FRANCIS KIM(Director)

Liv Labs develops pelvic floor fitness products, including the Pippa® Resistance Spring, designed to improve pelvic floor strength for women.

FemTechHardwareHealthtechWellness & FitnessChicago, US

MRMelody Roberts(Founder)inCPCarly Price(Founder)inDMDr. Melissa Stendahl(PT, Co-leader)in

Co-investorsY Y CombinatorHAHarvard Management Company

Livivos develops point-of-care medical devices for liver disease diagnosis, with expertise in magnetic resonance technology.

BiotechDeep TechHealthtechMedical DevicesLa Jolla, US

Pablo J Prado(Founder & CEO)inRobert Lown(Co-founder & Systems Engineering Lead)

Localized Therapeutics is a pre-revenue biotechnology company developing therapeutic resonance technology to treat cancer by identifying resonance frequencies specific to a patient's tumor DNA and generating those frequencies to destroy cancer cells while sparing healthy tissue.

BiotechHealthtechMedical Devices

Lodestone Biomedical develops biosensing and monitoring tools for the tumor microenvironment in preclinical cancer research models, enabling detection of immune response during early-stage drug discovery.

BiotechDeep TechHealthtechLebanon, US

Solomon Diamond(Executive Officer, Director)inLidia Valdes(Executive Officer, Director)

Longevity Biotech develops therapies for neurodegenerative diseases, primarily Parkinson's disease, using two proprietary platforms that profile and reset patient immune systems.

BiotechDeep TechHealthtechLongevityMedical Devices

LongWave Photonics designs and manufactures distributed feedback quantum cascade lasers operating in the terahertz frequency range.

Deep TechHardwareNew MaterialsSemiconductors

Loxagen develops oral therapeutic candidates targeting blood clotting disorders and Type 1 Diabetes, leveraging inhibition of lipoxygenase enzymes.

BiotechHealthtech

Kalidip Choudhury(CEO/Co-founder)Michael Holinstat(Scientific Founder, Professor at University of Michigan)Theodore Holman(Scientific Founder, Professor at UC Santa Cruz)

LTS Computing installs and supports OHDSI open-source observational research tools and converts claims and EHR datasets to the OMOP Common Data Model.

Data & InfrastructureDigital HealthHealthtech

Lucendi develops AI-enabled smart measurement platforms using computational microscopy and holographic imaging for micro-object detection and characterization across various industrial and scientific applications.

AI & Machine LearningDeep TechHardwareLos Angeles, US

Maxim Batalin(Executive Officer, Director)Aydogan Ozcan(Director)

BoardGilbert Hakim(Director)

Lucerna Technologies develops proprietary fluorescent dyes and custom sensors designed to detect medically relevant RNA molecules with high specificity and sensitivity.

AI & Machine LearningBiotechDeep TechBrooklyn, US

Cornell University scientists (Jaffrey lab)

Lucidact provides nurse-led remote patient monitoring and virtual care for Medicare and Medicaid patients with chronic conditions such as hypertension, heart disease, and diabetes.

Digital HealthHealthtechMedical Devices

Cheong AngGrace Chen

Co-investors50500 GlobalSOSocial Starts

Luciole Pharma is a biotech company focused on metabolic and inflammatory diseases through mitochondrial-targeted therapeutics.

AI & Machine LearningBiotechDeep TechHealthtechLongevityNatick, US

Dennis Goldberg, PhD(President and CEO, Director, Co-founder)Bill Rumsey, PhD(Vice President and CSO, Director, Co-founder)Eric Morrel, PhD(Vice President and COO, Director, Co-founder)Dennis I. Goldberg(Chief Executive Officer)Dr. Lloyd

Lucira Health manufactures portable diagnostic devices that connect to smartphones to test bodily fluids for infectious diseases, enabling rapid results outside of clinical settings.

BiotechHealthtechMedical DevicesEmeryville, US

DMDebkishore Mitra(Founder)inJohn R. Waldeisen(Director)

BoardErik T. Engelson(Executive Officer, Director)Justin Butler(Director)Tuff Yen(Director)Steve Tablak(Director)

Co-investors1111.2 CapitalFOForesite CapitalSHShangBay Capital LLCY Y CombinatorDCDCVC (Data Collective)DHDHVC+6 more

Ludlum Measurements designs and manufactures radiation detection instruments used for personnel monitoring, environmental safety, border security, and emergency response.

Advanced ManufacturingDeep TechDefense TechHardwareSweetwater, US

Don Ludlum

Lumen Bioscience develops orally and intranasally delivered biologic drugs and protein-based nutrition products using genetically engineered spirulina algae to express therapeutic proteins such as antibodies, enzymes, and cytokines.

BiotechDeep TechHealthtechSeattle, US

Erik Anderson(Director)Mark Litton(Director)Robert Carlson(Director)Craig Behnke(Executive Officer)Ed Schlect(Director)John Morrow(Executive Officer)

Co-investorsSASamsara BioCapital

Lumetrics develops optical imaging and photonics technologies for precision measurement and inspection in industries including medical devices, automotive, and ophthalmic sectors.

Advanced ManufacturingDeep TechHardwareMedical DevicesRochester, US

Chris Cotton(Co-Founder and Board Member)John Hart(President and CEO)

Co-investorsTOTopmark Partners

Lumicell develops a fluorescence-guided intraoperative imaging technology, including its LUMISIGHT optical imaging agent, that illuminates cancerous tissue in the surgical cavity to help surgeons remove residual cancer during procedures such as lumpectomy.

BiotechHealthtechMedical DevicesNewton, US

JFJorge Ferrer(Co-Inventor & Chief Scientific Officer)inWDW. David Lee(Co-Founder)inHHHoward Hechler(Executive Officer)inMarnie Curbow(Chief Commercial Officer)inJRJulio Rodriguez(Head of Finance)in

BoardCosimo Fiorenza(Director)

Co-investorsKIKinled HoldingLALaunchCapitalLALaunch Capital

Luminit provides LED lighting and photonics products and technologies for the industry, supporting partners in delivering solutions to the LED lighting and photonics sectors.

Advanced ManufacturingDeep TechHardwareNew MaterialsTorrance, US

Lumitex designs and manufactures specialized lighting solutions for medical devices and industrial applications.

Advanced ManufacturingHardwareHealthtechMedical DevicesStrongsville, US

PBPeter Broer(President / CEO)inSBScott Bogard(Executive Officer)in

BoardMaynard Murch(Director)Richard Gridley(Director)Jonathon Adams(Director)Steven Walling(Director)

LumiThera develops the Valeda Light Delivery System, an FDA-authorized photobiomodulation (PBM) device that applies multiple light wavelengths to treat early and intermediate dry age-related macular degeneration (AMD).

BiotechHealthtechMedical DevicesPoulsbo, US

TPTracy Puckett(Executive Officer)Clark Tedford(Executive Officer, Director)inSBScott Bradley(Executive Officer)inDMDuane Morrison(Executive Officer)inCCCindy Croissant(Executive Officer)RMRyan Montecucco(Executive Officer)

Co-investors3E3E Bioventures CapitalEFEFung CapitalKEKeiretsu ForumLILife Sciences Greenhouse InvestmentsIMImagine VenturesKEKeiretsu Capital

Luna Innovations develops fiber optics, nanomaterials, and precision assembly solutions across multiple technical domains.

Advanced ManufacturingData & InfrastructureDeep TechHardwareNew MaterialsRoanoke, US

SAScott A. Graeff(Executive Officer, Director)inDavid Chanley(Director)Gary Spiegel(Director)George Gomez-Quintero(Executive Officer)Thomas Oldemeyer(Executive Officer)Brian J. Soller(Executive Officer)

Co-investorsPEPerot Jain

Luxel manufactures photocathodes for high-performance streak cameras used in scientific instrumentation, including ultra-flat cathodes optimized for precise time resolution.

Advanced ManufacturingDeep TechHardwareNew MaterialsFriday Harbor, US

A clinical practice management solution that enables healthcare providers to measure patient status during visits and monitor outcomes to optimize treatment delivery and patient compliance.

Digital HealthHealthtechIoTMedical Devices

Nortiva develops the LYNX drug delivery platform, an oral technology designed to provide long-acting, sustained dosing as a replacement for daily pills.

BiotechHealthtechMedical Devices

Lynntech provides scientific research, technology development, and prototype engineering services primarily for government-sponsored projects.

Deep TechDefense TechDeveloper ToolsEnterprise SoftwareMedical DevicesCollege Station, US

Lancaster, US

Solomon Luo(Director)Arthur Yang(Director)Caesar Luo(Director)Jeff Yang(Executive Officer, Director)

Lyssn provides AI-powered tools for behavioral health and child welfare organizations to reduce staff burnout and improve implementation of evidence-based practices.

AI & Machine LearningDigital HealthHealthtechMental HealthSaaSSeattle, US

Zachary E. Imel(Director, Promoter)DCDavid C. Atkins(Executive Officer, Director, Promoter)inMJMichael J. Tanana(Director, Promoter)in

BoardSeth Feuerstein(Director)

MAA Laboratories is a specialty pharmaceutical company developing nanoparticle-based drug products using its proprietary NanoCont™ continuous manufacturing platform to address unmet medical needs across multiple therapeutic areas.

BiotechDeep TechHealthtechMedical DevicesResearch Triangle Park, US

Dr. Anjani Jha(Founder and CEO)

Madorra develops a nonhormonal, noninvasive medical device to treat vaginal dryness and vulvovaginal atrophy, targeting post-menopausal people and breast cancer survivors.

FemTechHealthtechMedical DevicesPortland, US

HRHolly Rockweilerin

Co-investorsAVAvestria VenturesBEBerkeley CatalystONOneVenturesPOPortfoliaPOPortland Seed FundSOSocial Starts+1 more

MagiQ Technologies develops sensing, communications, and security systems—rooted in quantum science, high-speed electronics, and digital signal processing—for defense agencies, energy companies, wireless carriers, and critical infrastructure operators.

Deep TechDefense TechQuantum ComputingSomerville, US

Robert Gelfond(Executive Officer, Director)Audrius Berzanskis(Executive Officer)in

Magnetic Particle Imaging (MPI) is an imaging technology that detects iron oxide nanoparticle tracers using time-varying magnetic fields to create medical images with high contrast and sensitivity.

Deep TechHealthtechMedical Devices

Co-investors5A5AM VenturesALAlumni VenturesEVEvolution VC PartnersINInnolinks VenturesSASand Hill AngelsSHShangBay Capital LLC+2 more

Magnetic Tides develops kTMP, a non-invasive brain stimulation method for treating neurological and psychiatric disorders such as stroke, anhedonia, and depression.

BiotechDeep TechDigital HealthMedical DevicesBerkeley, US

Ludovica Labruna, PhD(CEO / Founder)Daniel Sheltraw, MD, PhD(CTO / Founder)Richard Ivry, PhD(Founder)

Mainstream Engineering develops and manufactures thermal management, power systems, refrigerated containers, and specialty products for government, military, commercial, and industrial applications.

Advanced ManufacturingDeep TechDefense TechEnergyHardwareRockledge, US

MAKScientific is a pharmaceutical company developing small-molecule drugs that target the endocannabinoid system, including cannabinoid receptors and regulatory enzymes, to treat conditions such as substance use disorders and metabolic diseases.

BiotechHealthtechBoston, US

A company focused on addressing malaria through research and solutions aimed at reducing the disease's health and economic burden.

BiotechHealthtechImpact & Social GoodSeattle, US

JHJodi Herczeg(Executive Officer)James Wayne Davie(Executive Officer, Director)

Managed Health Connections develops digital health solutions and customizable research platforms that support substance use disorder treatment, contingency management, screenings, and cognitive impairment tools, integrating with academic and EHR systems.

AI & Machine LearningDigital HealthHealthtech

Kim Johnson(Co-Founder & CEO)Carol Johnson(Co-Founder & CFO)

MandalMed develops protein-based treatments targeting glycobiology and innate immunity to prevent and reverse organ fibrosis, with an initial focus on heart disease.

BiotechHealthtechMedical DevicesSan Francisco, US

Dr. John(President & CEO)Dr. Mounzih(VP, Product Development)