🦊/Investors

MRL Ventures Fund β€” Full Portfolio

40 tracked investments Β· listed companies and verified rows first

Aktis Oncologyaktisoncology.cominNASDAQ: AKTSSep 2024 Β· $175M

Aktis Oncology discovers and develops targeted radiopharmaceuticals for treating solid tumors.

BiotechHealthtechMedical DevicesBoston, US

Todd Foley(Co-founder and Chairman)inPatrick Baeuerle(Co-founder & Advisor)inShulamit Ron-Bigger(Executive Officer)inKyle D. Kuvalanka(Chief Financial Officer)inAkos Czibere(Chief Medical Officer)inPaul L. Feldman(Chief Scientific Officer)in

Co-investorsAndreessen HorowitzEcoR1 CapitalMPM BioImpactPappas CapitalRA CapitalTCG Crossover+5 more

Alectoralector.comin𝕏NASDAQ: ALECSep 2015

Alector develops therapies targeting neurodegenerative diseases including Alzheimer's, frontotemporal dementia, and Parkinson's disease through protein removal, replacement, and immune cell restoration.

AI & Machine LearningBiotechHealthtechLongevityMedical DevicesSan Francisco, US

Arnon Rosenthal(Ph.D.)inTillman Gerngross(Director)Arnon Rosenthal PhD(Founder)in

BoardCarl Gordon(Director)Terry McGuire(Director)in

Co-investorsForesite CapitalMission Bay CapitalMission BiocapitalSV Health InvestorsPolaris Partners

Entrada Therapeutics, Inc.entradatx.cominNASDAQ: TRDA

Entrada Therapeutics is a biotech company developing intracellular therapeutics based on its proprietary EEV Platform, aimed at reaching previously inaccessible or undruggable disease-causing targets inside cells.

BiotechHealthtechBoston, US

Natarajan Sethuraman(Executive Officer)inNerissa Kreher(Executive Officer)inKory Wentworth(Executive Officer)inDipal Doshi(Chief Executive Officer)inNathan Dowden(Executive Officer)inNatarajan Sethuraman, PhD(President of Research and Development)

Co-investors5AM VenturesAgent CapitalMPM BioImpactRoche Venture FundTCG Crossover

Invivydinvivyd.comin𝕏NASDAQ: IVVD

Invivyd develops monoclonal antibody medicines for the prevention and treatment of serious viral infectious diseases, starting with COVID-19 and other high-need indications.

BiotechHealthtech

Marc Elia(Founder)in

Co-investorsBain Capital Life SciencesForesite CapitalPremji InvestGV (Google Ventures)MITHRILMithril Capital Management+3 more

Kymera Therapeuticskymeratx.comin𝕏NASDAQ: KYMR

Kymera is a clinical-stage biotechnology company developing novel medicines using targeted protein degradation technology to treat diseases caused by previously "undrugged" proteins.

BiotechDeep TechHealthtech

Nello Mainolfi(Founder)inBruce Booth(Chair)in

Co-investorsAtlas VentureAvoro Capital AdvisorsBain Capital Life SciencesBessemer Venture PartnersHatteras Venture PartnersNextech Invest+6 more

Spero Therapeuticssperotherapeutics.cominNASDAQ: SPRO

Spero Therapeutics is a clinical-stage biopharmaceutical company developing medicines for immune-mediated diseases, led by SP001, a third-generation anti-CD40L antibody targeting IgG4-related disease.

BiotechCambridge, US

Ankit Mahadevia(Executive Officer, Director)inStephen Garbacz(Executive Officer)inEsther Rajavelu(Director, President, Chief Executive Officer, Chief Financial Officer, Chief Business Officer and Treasurer)in

BoardJean-Francois Formela(Director)inReza Halse(Director)Casper Breum(Director)

Co-investorsHEALTHCARE ROYALTY PARTNERSOUP (Osage University Partners)RA CapitalAlphabetAtlas VentureFidelity Investments

Xilio Therapeuticsxiliotx.cominNASDAQ: XLO

Xilio Therapeutics is a clinical-stage biotechnology company developing masked immuno-oncology therapies that use protein engineering to remain inactive until activated by tumor-specific proteases within the tumor microenvironment.

BiotechHealthtechWaltham, US

RenΓ© Russo(Executive Officer, Director)inJoseph Farmer(Executive Officer)Timothy Clackson(Executive Officer)Christopher Frankenfield(Chief Financial and Operating Officer)inKatarina Luptakova(Chief Medical Officer)inPaul Clancy(Director)

Co-investorsBain Capital Life SciencesBay City CapitalF-Prime CapitalM VenturesRA CapitalRiverVest Venture Partners+9 more

ATB Therapeuticsatbtherapeutics.cominπ•βœ“ verified

ATB Therapeutics is a biotech company developing bispecific antibody therapies and related immunological treatments.

BiotechHealthtechMedical Devices

Dr. Mark Throsby(Chief Executive Officer)

Co-investorsV-Bio VenturesVIVES PartnersEQT Life SciencesSambrinvestWallonie Entreprendre

Axonis Therapeuticsaxonis.usinOct 2024βœ“ verified

Axonis Therapeutics is a biotechnology company developing small-molecule medicines that target KCC2, a mediator of inhibition in the brain, to treat neurological disorders such as epilepsy and pain.

BiotechDeep TechBoston, US

Shane V. Hegarty(Chief Scientific Officer & Co-Founder)inJoanna Stanicka(Chief Executive Officer, President & Co-Founder)inJeff Imbaro(Chief Operating Officer)inTiasha Shafiq(Chief of Staff)in

BoardCorey . Goodman(Director)inJonathan Leff(Director)in

Co-investorsvenBio PartnersSofinnova VenturesCivilization Ventures Management, LlcCreative Destruction Lab (CDL)Hatteras Venture PartnersIaso Ventures+8 more

InduProinduprotx.cominβœ“ verified

InduPro develops next-generation protein therapeutics by leveraging inherent and induced proximity to modulate disease biology, with a focus on ADCs and T-cell engagers.

BiotechDeep TechMedical DevicesSeattle, US

K. Chris Garcia(Scientific Founder)Prakash Raman(CEO)inAmanda J. Redig(Chief Medical Officer)inScott Lesley(President & CSO)inPamela Holland(SVP of Biology)inSally Johnson(Chief People Officer)in

Co-investorsThe Column GroupVida Ventures

Photys Therapeutics, Inc.photys.cominβœ“ verified

Photys Therapeutics develops bifunctional small-molecule medicines that use induced proximity to recruit kinases and drive targeted protein phosphorylation, aiming to modulate and repair disease-driving proteins.

BiotechHealthtechLongevityWaltham, US

Amit Choudhary(Scientific Founder)David Steinberg(Chairman & Founding CEO)inEdward Holson(Co-founder & CSO)inLizzie Ngo(Co-founder)inBrian Fenton(President & CEO)in

Co-investorsLongwood FundMPM BioImpact8VCOno Venture Investment, Inc.

Therini Biotherinibio.cominApr 2023 Β· $36Mβœ“ verified

Therini Bio is a biotechnology company developing fibrin-targeting therapeutics to treat neurological and ophthalmological diseases, leveraging scientific discoveries in neurovascular and neuroimmune mechanisms of disease.

BiotechDigital HealthHealthtechMedical DevicesSacramento, US

Katerina Akassoglou(Scientific Founder, Director of the Center for Neurovascular Brain Immunology and Professor of Neurology at UCSF and Gladstone Institutes)inKaterina Akassoglou, PhD(Scientific Founder)Leslie Schulze(Executive Officer)Tara Nickerson(Executive Officer, Director)in

BoardOlga Danilchanka(Director)inLaia Crespo-Martin(Director)

Co-investorsSanofi VenturesSV Health InvestorsAngelini VenturesMitsui Global InvestmentApollo Health VenturesDementia Discovery Fund+2 more

Topo Therapeuticstopo-tx.comDec 2024SEC filingmedium confidence

Topo Therapeutics is a drug discovery company developing treatments targeting ion channels and transmembrane proteins for conditions such as pain, epilepsy, and CNS, pulmonary, and renal diseases.

BiotechHealthtechCambridge, US

Hui Tian(Executive Officer, Director)inMadgalene Moran(Executive Officer, Director)Magdalene Moran(Chief Executive Officer)

BoardBruce Bean(Director)James Jeffrey Goater, Jr.(Director)

Board seatKarin KleinhansΒ· per SEC Form D Β· $95M raise Β· filed Dec 2024

Co-investorsSR One Capital ManagementThe Column Group

Ambagon Therapeuticsambagontx.comin𝕏Jan 2025

Ambagon develops small molecule stabilizers of 14-3-3 protein complexes to modulate disease-related protein interactions, targeting therapeutic areas including cancer, metabolic disorders, neurodegenerative and infectious diseases.

BiotechDeep TechMedical DevicesEindhoven, US

Christian Ottmann(Executive Officer)inJosh Seidenfeld(Executive Officer)Michelle Arkin(Director)Nancy Pryer(Executive Officer)Margarita Chavez(Director)Bryan Miller(Executive Officer)

Co-investorsDroia VenturesMission BiocapitalNextech InvestInkefRA Capital

Carawaycarawaytx.comin𝕏acquired by Merck

Caraway Therapeutics was a preclinical biopharmaceutical company developing small-molecule therapies modulating lysosomal function to treat neurodegenerative and rare diseases.

BiotechHealthtech

Co-investorsEisai Innovation, Inc.SV Health Investors

Carisma Therapeuticscarismatx.comDec 2020

CAR-Macrophage cellular therapeutics with initial oncology focus (NASDAQ: CARM).

BiotechPhiladelphia, US

Steven Kelly(Executive Officer, Director)in

BoardMargarita Chavez(Director)inEran Nadav(Director)Althea Stillman(Director)Jacob Gunterberg(Director)Regina Hodits(Director)in

Co-investorsAgent CapitalAju IB Invesment CorporationAnzu PartnersGrazia Equity GmbHHealthCapSolasta Ventures+3 more

HotSpot Therapeuticshotspotthera.comin𝕏

HotSpot Therapeutics develops novel biopharmaceutical products and therapeutic platforms focused on innovative biomedical technologies.

AI & Machine LearningBiotechHealthtech

BoardBruce Booth(Chairman)in

Co-investorsAtlas VentureB Capital GroupB4 CapitalSofinnova PartnersSolasta VenturesSR One Capital Management+1 more

Imagoimagobio.comin𝕏Nov 2020 Β· $80M

A pharmaceutical company that develops medicines and vaccines, with research pipelines and clinical trials aimed at new treatments.

BiotechHealthtech

Co-investorsHighlight CapitalAmgen VenturesBlackRockBlackstone Life SciencesClarus VenturesFrazier Healthcare Partners+4 more

Insamoinsamo.com

Insamo develops an automated platform for drug discovery that designs, synthesizes, and tests cyclic peptides at scale using machine learning and proprietary experimental data.

AI & Machine LearningBiotechDeep TechChippendale, AU

Tim Craven(CEO)inToby Passioura(CSO)inGlen McIntyre(COO)

BoardCOREY GOODMAN(Director)inMATT HERSHENSON(Director)in

Co-investorsBEVCCivilization Ventures Management, LlcPlayground GlobalvenBio PartnersAxial VCvenBio Global Strategic

LAVA Therapeuticslavatherapeutics.comin𝕏Sep 2020

LAVA develops the Gammabody platform, which generates bispecific antibodies that activate gamma-delta T cells to treat cancer by directing immune cells to tumors and triggering anti-cancer immune responses.

AI & Machine LearningBiotechHealthtechMedical Devices

Ton AdanginHans van der Vliet(Head of Innovation)inSteve Hurly(Chief Executive Officer)Oxana Polyakova(Chief Scientific Officer)in

Co-investorsSanofi VenturesYsios CapitalGilde HealthcareREDMILE

Mozart Therapeuticsmozart-tx.comJun 2023 Β· $25M

Mozart Therapeutics develops protein therapeutics focused on immunology and oncology treatments.

BiotechMedical Devices

Mark Davis(Scientific Co-Founder)K. Christopher Garcia(Scientific Co-Founder)Calvin Kuo(Scientific Co-Founder)Katie Fanning(President & Chief Executive Officer)in

Co-investorsARCH Venture PartnersJDRF T1D FundOno Venture Investment, Inc.Pfizer Venture InvestmentsSofinnova PartnersAlexandria+4 more

Msdmsd.comin𝕏

MSD is a pharmaceutical company focused on developing medicines and vaccines for patients globally, guided by a science-led innovation strategy.

BiotechHealthtechMedical Devices

PAQ Therapeuticspaqtx.comin

Developing novel KRAS degraders.

Burlington, US

Huaixiang Hao(Founder)in

Tallac Therapeuticstallactherapeutics.comin

Tallac Therapeutics is a clinical-stage biopharmaceutical company developing oligonucleotide-based antibody conjugates (TRAAC candidates) designed to deliver immune-activating agents to tumor microenvironments for oncology indications.

BiotechHealthtechMedical DevicesBurlingame, US

Hong Wan(Executive Officer, Director)in

BoardRan Geng(Director)Michael Carusi(Director)Isaac Cheng(Director)Christine Brennan(Director)Corey Goodman(Director)in

Co-investorsLightstone VenturesvenBio PartnersMatrix Partners ChinavenBio Global Strategic

Tidal Therapeuticssanofi.comin𝕏acquired by Sanofi

Sanofi is an R&D-driven, AI-powered biopharmaceutical company that develops medicines and vaccines, with a focus on immunology and the immune system.

AI & Machine LearningBiotechHealthtech

Co-investorsNew Enterprise Associates (NEA)Rho VenturesSanofi VenturesFJ Labs

Viridian Therapeuticsviridiantherapeutics.comin𝕏

Viridian Therapeutics develops treatments for thyroid eye disease, a rare autoimmune condition affecting the eyes and orbit.

BiotechDigital HealthMedical DevicesWaltham, US

Jonathan Violin(Executive Officer, Director)in

BoardPeter Harwin(Director)Tomas Kiselak(Director)

Co-investorsBroadview VenturesLongitude Capital

VISTERRA, INC.visterrainc.cominacquired by Otsuka

A biologics center of excellence focused on developing and delivering medicines to patients, operating as a subsidiary within the Otsuka pharmaceutical group.

AI & Machine LearningBiotechHealthtechMedical Devices

Zachary Shriver(President and Chief Executive Officer)Karthik Viswanathan(Vice President, Research)in

Co-investorsCTI Life Sciences Fund L.P.Cycad Group LLCLux Capital

Other

Tracked investments with no reachable website or further public details β€” typically companies that wound down, renamed, or were absorbed.

ADRxAnavo TherapeuticsAxonisEyeBioGlobal Health Innovation FundImago BiosciencesLifeMineMyoventivePhotysRay TherapeuticsTopoTranslate BioVectorY Therapeutics

Rows marked β€œSEC filing” are inferred from directors named on the company's SEC Form D β€” public regulatory data, not a portfolio list published by the firm.