HARPER COURT VENTURES
Venture capitalChicago · Pre-Seed–Seed · 1 people tracked
Investment thesis
Harper Court Ventures backs pre-seed startups built on University of Chicago research breakthroughs, targeting frontier technologies in quantum computing, life sciences, energy, and AI/data sciences. It invests in ventures spun out of university labs, accelerated by the Polsky Center, or founded by University of Chicago alumni. Led by Chicago Booth alum Karthee Madasamy and managed by MFV Partners, a Silicon Valley deep tech fund, it aims to be an engine of deep tech innovation for the Midwest and beyond.
Source: firm website, verified Aug 3, 2026.
Team · 1 people
from the firm's website
What they invest in
from 9 of 10 portfolio companiesDigital Health ×3Hardware ×3Healthtech ×3AI & Machine Learning ×2Consumer ×2Logistics & Supply Chain ×2Medical Devices ×2Biotech ×1
HQs:United States×4Australia×1India×1
Investments · 10 tracked
founders shown can be your intro path
Agility Robotics develops and deploys humanoid robots for warehouse automation and logistics operations.
AI & Machine LearningHardwareLogistics & Supply ChainRoboticsSalem, US
Jonathan Hurst(Co-founder & Chief Robot Officer)inDamion Shelton(Co-Founder & Chairman of the Board)in
BoardBruce Leak(Director)inMatthew Ocko(Director)in
PartnerKarthee Madasamy· solo GP
Co-investorsBig Brain HoldingsDCVC (Data Collective)Manhattan Venture PartnersMFV PartnersNVenturesPlayground Global+5 more
Beacon makes a consumer smart-home device that uses 222nm Far-UVC light to disinfect air and surfaces, eliminating airborne and surface pathogens without chemicals.
ConsumerHardwareHealthtech
PartnerKarthee Madasamy· solo GP
Co-investorsHolly VenturesNotable Capital
Flow Medical develops technology for catheter-directed thrombolysis treatment of pulmonary embolism, aiming to improve precision in lytic medication dosing to reduce readmission rates.
Digital HealthHealthtechMedical DevicesChicago, US
Jonathan Paul(Co-Founder, Chief Scientific Officer)inOsman Ahmed(Co-Founder, Chief Medical Officer)in
PartnerKarthee Madasamy· solo GP
Co-investorsThe Innovation Space
MapMyIndia provides digital mapping and location-based services for various applications and industries in India.
Data & InfrastructureIoTLogistics & Supply ChainDelhi, IN
Rashmi Verma(Founder)in
PartnerKarthee Madasamy· solo GP
Co-investorsMFV PartnersQualcomm VenturesLightbox
NOMO is a mobile app that helps people reduce time spent scrolling on social media by rewarding milestones with "Moments" that can be redeemed for perks like sports tickets, merchandise, concerts, and cash-back.
ConsumerSocialWellness & Fitness
PartnerKarthee Madasamy· solo GP
OrisDX develops a non-invasive salivary-rinse DNA test called Oro Lesion to detect early markers of oral cavity squamous cell carcinoma in adults with indeterminate oral lesions.
BiotechDigital HealthMedical DevicesChicago, US
Harald Steltzer(Executive Officer, Director)inPatrick Conniff(Executive Officer)inEvgeny Izmchenko(Director)Nishant Agrawal(Director)in
PartnerKarthee Madasamy· solo GP
Co-investorsAngel Physicians Fund
PsiQuantum builds fault-tolerant quantum computers using photonic qubits and semiconductor manufacturing processes.
Deep TechHardwareQuantum ComputingSemiconductorsMoreton Bay, AU
Prof. Jeremy O'Brien(Co-founder & Executive Chairman)Prof. Terry Rudolph(Co-founder & Chief Architect)Dr. Pete Shadbolt(Co-founder & Chief Scientific Officer)Prof. Mark Thompson(Co-founder & Chief Technology Officer)Jeremy O'Brien(Founder)inVictor Peng(Chief Executive Officer)
PartnerKarthee Madasamy· solo GP
Co-investorsBlackbird VenturesC4 VenturesCold Start VenturesFounders FundFPVIntegra Groupe+23 more
SimCare provides AI-powered avatar-based simulation practice for counseling and mental health training programs.
AI & Machine LearningDigital HealthEdTechHealthtechNew York City, US
Vrishank Saini(Founder)inTiko Bdoyan(Founder)in
PartnerKarthee Madasamy· solo GP
Co-investorsTranspose Platform ManagementY CombinatorGoodwater Capital
SUN Mobility provides swappable battery systems for electric vehicles using a pay-as-you-go model that separates the battery from the vehicle.
CleantechEnergyMobility & Transportation
PartnerKarthee Madasamy· solo GP
Co-investorsHelios Digital VenturesBosch
Noam Bardinin
PartnerKarthee Madasamy· solo GP
Co-investors10DHorizons VenturesKleiner PerkinsMFV PartnersQualcomm Ventures
Portfolio news
latest coverage across their companiesBeacon · securityweek.com · Jul 17, 2026
PsiQuantum · quantumcomputingreport.com · Sep 11, 2025
MapmyIndia · entrepreneur.com · Sep 4, 2025
SUN Mobility · trilegal.com · Aug 6, 2025
SimCare · finsmes.com · Mar 3, 2025
Frequently asked questions
- How many investments has HARPER COURT VENTURES made?
- HARPER COURT VENTURES has 10 tracked investments, including 1 dated in the last 24 months.
- What stage does HARPER COURT VENTURES invest at?
- HARPER COURT VENTURES invests at the Pre-Seed, Seed stages.
- What sectors does HARPER COURT VENTURES focus on?
- HARPER COURT VENTURES focuses on AI & Machine Learning, Biotech, Data & Infrastructure, Deep Tech, Energy, Quantum Computing.
- Where is HARPER COURT VENTURES located?
- HARPER COURT VENTURES is headquartered in Chicago, US.
- Who does HARPER COURT VENTURES co-invest with?
- HARPER COURT VENTURES most often shares deals with MFV Partners, Playground Global, Qualcomm Ventures, among 41 tracked co-investors.
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