HARPER COURT VENTURES
Venture capitalChicago · Pre-Seed–Seed · 1 people tracked
Investment thesis
Harper Court Ventures backs pre-seed startups built on University of Chicago research breakthroughs, targeting frontier technologies in quantum computing, life sciences, energy, and AI/data sciences. It invests in ventures spun out of university labs, accelerated by the Polsky Center, or founded by University of Chicago alumni. Led by Chicago Booth alum Karthee Madasamy and managed by MFV Partners, a Silicon Valley deep tech fund, it aims to be an engine of deep tech innovation for the Midwest and beyond.
Source: firm website, verified Aug 3, 2026.
Team · 1 people
from the firm's website
What they invest in
from 6 of 10 portfolio companiesDigital Health ×3AI & Machine Learning ×2Hardware ×2Healthtech ×2Logistics & Supply Chain ×2Medical Devices ×2Biotech ×1Data & Infrastructure ×1
HQs:United States×4Australia×1India×1
Investments · 10 tracked
founders shown can be your intro pathAgility Robotics develops and deploys humanoid robots for warehouse automation and logistics operations.
AI & Machine LearningHardwareLogistics & Supply ChainRoboticsSalem, US
Jonathan Hurst(Co-founder & Chief Robot Officer)inDamion Shelton(Co-Founder & Chairman of the Board)inBruce Leak(Director)Matthew Ocko(Director)
PartnerKarthee Madasamy· solo GP
PartnerKarthee Madasamy· solo GP
Flow Medical develops technology for catheter-directed thrombolysis treatment of pulmonary embolism, aiming to improve precision in lytic medication dosing to reduce readmission rates.
Digital HealthHealthtechMedical DevicesChicago, US
Jonathan Paul(Co-Founder, Chief Scientific Officer)inOsman Ahmed(Co-Founder, Chief Medical Officer)in
PartnerKarthee Madasamy· solo GP
MapMyIndia provides digital mapping and location-based services for various applications and industries in India.
Data & InfrastructureIoTLogistics & Supply ChainDelhi, IN
PartnerKarthee Madasamy· solo GP
PartnerKarthee Madasamy· solo GP
OrisDX develops salivary diagnostics for early disease detection, starting with oral cancer.
BiotechDigital HealthMedical DevicesChicago, US
Harald Steltzer(Executive Officer, Director)Evgeny Izmchenko(Director)Patrick Conniff(Executive Officer)Nishant Agrawal(Director)
PartnerKarthee Madasamy· solo GP
PsiQuantum builds fault-tolerant quantum computers using photonic qubits and semiconductor manufacturing processes.
Deep TechHardwareQuantum ComputingSemiconductorsMoreton Bay, AU
Prof. Jeremy O'Brien(Co-founder & Executive Chairman)Prof. Terry Rudolph(Co-founder & Chief Architect)Dr. Pete Shadbolt(Co-founder & Chief Scientific Officer)Prof. Mark Thompson(Co-founder & Chief Technology Officer)Victor Peng(Chief Executive Officer)
PartnerKarthee Madasamy· solo GP
SimCare provides AI-powered avatar-based simulation practice for counseling and mental health training programs.
AI & Machine LearningDigital HealthEdTechHealthtechNew York City, US
Vrishank Saini(Founder)inTiko Bdoyan(Founder)in
PartnerKarthee Madasamy· solo GP
PartnerKarthee Madasamy· solo GP
PartnerKarthee Madasamy· solo GP
Portfolio news
latest coverage across their companiesMapmyIndia · entrepreneur.com · Sep 4, 2025
SimCare · finsmes.com · Mar 3, 2025
Frequently asked questions
- What stage does HARPER COURT VENTURES invest at?
- HARPER COURT VENTURES invests at the Pre-Seed, Seed stages.
- What sectors does HARPER COURT VENTURES focus on?
- HARPER COURT VENTURES focuses on AI & Machine Learning, Biotech, Data & Infrastructure, Deep Tech, Energy, Quantum Computing.
- Where is HARPER COURT VENTURES located?
- HARPER COURT VENTURES is headquartered in Chicago, US.
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