BioAdvance — Full Portfolio

Palvella Therapeutics develops QTORIN™, a targeted topical formulation of rapamycin designed to treat rare skin diseases including microcystic lymphatic malformations and cutaneous venous malformations by delivering the active ingredient to the dermal layers with minimal systemic absorption.

BiotechDigital HealthHealthtechMedical DevicesWayne, US

Wesley H. Kaupinen(President, Chief Executive Officer and Director)Matthew E. Korenberg(Chief Financial Officer, Treasurer and Secretary)inKathleen Goin(Chief Operating Officer)inJeffrey Martini(Chief Scientific Officer)inAKAshley Kline(Chief Commercial Officer)in

Co-investorsFRFrazier Life SciencesSASamsara BioCapitalAGAgent Capital

QR Pharma is a clinical-stage biopharmaceutical company developing buntanetap, an orally administered small molecule that inhibits the synthesis of multiple neurotoxic proteins implicated in Alzheimer's disease and Parkinson's disease.

BiotechBerwyn, US

Maria Maccecchini(Executive Officer, Director)

BoardDhesh Govender(Director)Michael Hoffman(Director)Franz F. Hefti(Director)

Co-investorsKEKeiretsu ForumBEBen Franklin Technology Partners

Relmada is a clinical-stage biopharmaceutical company developing therapies including NDV-01, a sustained-release intravesical formulation of gemcitabine and docetaxel for non-muscle invasive bladder cancer, and Sepranolone, a candidate targeting compulsive behaviors via GABAA receptor modulation.

BiotechHealthtechNew York, US

Sergio Traversa(Executive Officer, Director)Paul Kelly(Director)Maged Shenouda(Director)inEOEliseo O. Salinas(President and Chief Scientific Officer)inDouglas Beck(Chief Financial Officer)Charles Ence(Chief Accounting and Compliance Officer)

Co-investorsBABAM ElevateBRBraidwellCOCommodore CapitalJAJanus Henderson InvestorsOROrbiMedRARA Capital+2 more

RiboNova is a biopharmaceutical company developing small molecule drugs and precision medicines targeting transfer RNA for the treatment of mitochondrial disease.

BiotechDeep TechMedical DevicesWynnewood, US

Co-investorsMIMilitia Hill Ventures

Accelerated Biosciences commercializes human trophoblast stem cells (hTSC) and derived platforms for therapeutic development, serving pharmaceutical and biotech partners seeking accelerated pathways to clinical products.

BiotechHealthtechMedical Devices

Bainbridge Health provides software solutions for hospital pharmacy operations, including infusion safety analytics, IV formulation management, and drug library development.

Data & InfrastructureDigital HealthEnterprise SoftwareHealthtechMedical DevicesPhiladelphia, US

SWSam Wilson(Executive Officer)inJoseph Kaupp(Executive Officer, Director)Sean O'Neill(Executive Officer, Director)

BoardAmy Gallagher(Director)Shahram Hejazi(Director)Thomas Lynch(Director)

Co-investorsCHChestnut Street Ventures

Concarlo Therapeutics develops cancer therapeutics that target CDK4/6-driven cell proliferation and CDK2-driven resistance, focusing on improving outcomes for cancer patients through novel approaches in p27 biology.

BiotechBrooklyn, US

SBStacy Blain(Founder, CEO)inLisaMarie Casey(President and Manager)

BoardJMJason Mraz(Executive Board Member)in

Co-investorsCRCreative Destruction Lab (CDL)RARaptor Group

Eliksa Therapeutics develops innovative treatments for rare diseases with unmet medical needs.

BiotechDigital HealthMedical Devices

Co-investorsMIMilitia Hill VenturesBEBen Franklin Technology Partners

ENB Therapeutics develops small molecules targeting the endothelin B receptor (ETBR) in the tumor microenvironment to treat drug-resistant cancers by restoring immune cell infiltration and promoting tertiary lymphoid organ formation.

BiotechHealthtechNew York, US

Sumayah Jamal(President, Co-founder & Chief Scientific Officer)inRSRobert Schneider(Co-founder & Chair of Scientific Advisory Board)inSandy Harm(Chief Operating Officer)inFumitaka Mori(Director)Albert Sokol(Executive Officer)

BoardBarbara Schilberg(Director)

Co-investorsRERemiges Ventures, Inc.

Hanimune Therapeutics develops therapeutics for food allergy prevention and tolerance support for pediatric and adult patients, drawing on immunological science and food protein research.

BiotechFoodTechHealthtechMedical Devices

MLMeenal Lele(Founder)in

Co-investorsRORobin Hood Ventures

ImmunoGenesis is a clinical-stage immuno-oncology biopharmaceutical company developing immune therapies for immune-excluded tumors, which resist standard PD-1 blockade.

BiotechHealthtechMedical DevicesDoylestown, US

MAMichael A. Curran(Director)inJennifer Barlow(Executive Officer, Director)Clifford Stocks(Director)James Barlow(Executive Officer, Director)Jeremy Barton(Executive Officer)Federica O'Brien(Executive Officer)

Co-investorsADAdit Ventures Management, LlcANAngel Physicians FundSEService Provider CapitalTETexas HALO Fund

BiotechNew York, US

Nader Halim(Executive Officer, Director)Althea Stillman(Executive Officer, Director)

BoardJonathan Leff(Director)David Greenwald(Director)in

Co-investorsDEDeerfield Management Company

BiotechCranbury, US

Bo Liang(Executive Officer, Director)Houman Hemmati(Executive Officer, Director)Wei Wang(Executive Officer, Director)John J Baldwin(Director)Tao Du(Director)

BoardQi Zhu(Director)

KaloCyte develops ErythroMer, a dried, shelf-stable artificial red blood cell for use in emergency and trauma care when stored blood is unavailable or in short supply.

BiotechDeep TechHealthtechMedical DevicesBaltimore, US

ADAllan Doctor(Co-Founder & CSO)inDPDipanjan Pan(Co-Founder, Chief Technical Officer)inPSPhilip Spinella(Co-Founder, Chief Medical Officer)inDaniel Getman(Director)Gregory Lanza(Director)

Co-investorsBIBioGenerator VenturesMAMaryland TEDCONYNYBC VenturesOLOld Line Capital PartnersTETEDCO

Keriton offers a software platform for neonatal and pediatric hospital settings that supports safe infant feeding practices, milk management (donor human milk, formula, and parental human milk), and family engagement through features like secure photo sharing, e-journaling, and clinician messaging.

BiotechDigital HealthHealthtechSaaSPhiladelphia, US

VSVidur Shailendra Bhatnagar(Manager)

Co-investors3737 AngelsBRBroad Street AngelsDODorm Room

Loudmark is a marketing and design agency that provides advertising, branding, graphic design, web development, event production, and packaging services to clients.

AdTechMarketing TechPeachtree City, US

Co-investorsFIFitz Gate Ventures

Melior Discovery provides in vivo pharmacology services and phenotypic screening platforms for pharmaceutical and biopharmaceutical companies to evaluate candidate therapeutics in animal disease models.

AI & Machine LearningBiotechDeep TechHealthtechMedical Devices

ARAndrew Reaume(President and CEO, Co-Founder)inAndrew Reaume, PhD, MBA(President and CEO, Co-Founder)

HealthtechWilmington, US

Christopher Berlind(Executive Officer, Director)inDavid Lindsay, Jr.(Executive Officer, Director)

BoardGary Kurtzman(Director)

Co-investorsCOCota CapitalDODorm Room

Ossianix develops TXP1, a brain-selective shuttle based on a deimmunised VNAR antibody scaffold that targets TfR1 to carry therapeutic payloads across the blood-brain barrier.

BiotechDeep TechHealthtech

Frank S Walsh(CEO (Founder))JLJ Lynn Rutkowski(CSO (Founder))inSMSteve Moore(COO)inPSPawel Stocki(VP Research)in

Phrase Health provides analytics tools for health systems to reduce unwarranted clinical variation within the electronic health record (EHR), aiming to lower costs and improve patient outcomes.

Digital HealthHealthtechSaaSPhiladelphia, US

MTMarc Tobias, MD, FAMIA(Founder)inMichael Zeidlhack(Executive Officer, Director)MTMarc Tobias(Founder)inNMNaveen Muthu(Director)in

Co-investorsLILionBird

Ermit designs and manufactures connected hardware devices with embedded software and AI capabilities, serving companies building IoT and field-operated products.

CybersecurityHardwareIoTNew York, IT

Emanuele Musini(CEO and Director)JWJames Wyman(CFO and Director)

BoardYogendra Jain(Director)

Co-investorsCICivilization Ventures Management, LlcHAHackensack Meridian Health Bear's DenHIHikma VenturesSASamsung VenturesSTStanley Ventures

BiotechGreenwhich, US

WDWendy DiCicco(Ms. DiCicco is the Secretary and Treasurer of the Issuer.)inArthur Feldman(Director)Magdalene Cook(Executive Officer, Director)Campbell Murray(Director)Edward J. Benz, Jr.(Director)TNThomas Needham(Director)in

Co-investorsELElysia CapitalBRBroadview VenturesINInnogest CapitalNENew Leaf Venture PartnersNONovartis Venture Fund

Ride Health connects healthcare organizations with transportation services to ensure patients, particularly older adults and people with disabilities, can reliably access medical care.

B2B MarketplacesHealthtechLogistics & Supply ChainSaaSSan Francisco, US

ICImran Cronk(Founder)inDaniel Faath(Executive Officer, Director)Michael Reardon(Executive Officer)Cindy Nguyen(Executive Officer)

BoardTPTodd Pietri(Director)inSamir Malik(Director)

Co-investorsEXExcelerate Health VenturesACActivate Venture PartnersACActivate VenturesBRBridge BankLELeading Edge VenturesNENewark Venture Partners+2 more

Spirovant is a gene therapy company developing treatments for cystic fibrosis and other respiratory diseases, including viral vector-based therapies for airway epithelia.

BiotechHealthtechPhiladelphia, US

JLJoan Lau(Co-founder & Chief Executive Officer)EYEric Yuen(Co-founder & Chief Medical Advisor (former CMO))inJHJane Hollingsworth(Co-founder & Executive Chair of the Board)inRKRoland Kolbeck(Chief Scientific Officer & Co-owner)inEric Pastor(Chief Technology Officer)inDWDavid Whitwell(Chief Financial Officer)in

Co-investorsMIMilitia Hill Ventures

Tolerance is a compliance platform that runs continuous automated checks against the NIST 800-171 standard and collects assessor-ready evidence for teams handling Controlled Unclassified Information (CUI).

CybersecurityGovTechSaaS

Co-investorsDODorm RoomAMAmadeus Capital PartnersBEBen Franklin Technology PartnersCOColumbus Venture PartnersCRCriteria Bio VenturesEAEast Innovate+4 more

Tolerance Bio develops therapeutics targeting the thymus—the regulator of immune tolerance—to preserve, restore, and manipulate its function and extend health span.

BiotechDeep TechLongevityPhiladelphia, US

FLFrancisco Leon(Executive Officer, Director)inPhilip Ball(Executive Officer, Director)Justin Vogel(Executive Officer, Director)in

BoardDamia Tormo Carulla(Director)PCPablo Cironi(Director)inRobert Goldstein(Director)

Co-investorsCRCriteria Bio VenturesBEBen Franklin Technology PartnersCOColumbus Venture Partners

Vesteck develops medical device technology in the cardiovascular/endovascular space.

HealthtechMedical DevicesWest Chester, US

JWJOSEPH W. RAFFERTY(Executive Officer, Director, Promoter)inRJRafferty Joseph(Executive Officer, Director)inEdward Wulfman(Executive Officer)John Edoga(Director)JOHN DIEDERICH(Director)THIERRY RICHARD(Director)

Co-investorsNENew World AngelsOCOcean Azul PartnersRORobin Hood Ventures

Vittoria develops immunotherapies, specifically CAR T-cell therapies, to treat difficult-to-treat diseases including cancers beyond B-cell types.

BiotechDeep TechMedical DevicesPhiladelphia, US

Nicholas Siciliano(Director)inPreston Noon(Executive Officer)

BoardGeeta Vemuri(Executive Officer, Director)Bruce Peacock(Executive Officer, Director)Leon Moulder(Director)

Co-investorsAGAgent CapitalGLGlobal BioAccess Fund

Wellsheet builds a clinical workflow support system that uses machine learning to predict physicians' information needs and present a structured, comprehensive view of patient data at the point of care.

AI & Machine LearningDigital HealthHealthtechNew York, US

CLCraig Limoli(Executive Officer, Director, Promoter)inDaniel Larkin(Executive Officer, Director, Promoter)

Co-investorsBEBeni Venture CapitalREReal-Life InnovationsREREDO VenturesSPSpringTide VenturesNENewark Venture PartnersNVNVP Capital