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Tolerance Bio

Philadelphia, US · Founded 2023 · Delaware corporation · 17 employees on LinkedIn · 6 known investors

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Tolerance Bio develops therapeutics targeting the thymus—the regulator of immune tolerance—to preserve, restore, and manipulate its function and extend health span. Its work includes iPSC-derived thymic organoids and licensed interleukin-7 therapy aimed at improving thymic function and immune resilience.

BiotechDeep TechLongevity

Founders & leadership

Tolerance Bio was founded in 2023 by Francisco Leon.

FLFrancisco Leon
Francisco LeonFounder, CEO, ChairmanFrancisco Leon is an immunologist who co-founded Provention Bio (acquired by Sanofi in 2023), where he served as Chief Scientific Officer, and Celimmune (acquired by Amgen in 2017), where he served as Chief Medical Officer and Chief Executive Officer. His expertise spans immunodeficiencies, allergy, infectious diseases, immuno-oncology, transplantation, and autoimmunity, with extensive experience in drug development and clinical trial design across academic and pharmaceutical settings.
PB
Philip BallExecutive
JV
Justin VogelFounding Team Member, CFO, Director

Board

DT
Damia Tormo CarullaBoard director
PCPablo Cironi
Pablo CironiBoard MemberManaging Director at Criteria Bio Ventures
RG
Robert GoldsteinBoard director

Investors · 6

Criteria Bio Ventureslisted by Criteria Bio VenturesBarcelona

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Ben Franklin Technology PartnersreportedHarrisburg · $50K – $250K

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Columbus Venture PartnersreportedValencia

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Also in the syndicate · 2

Beyond CeliacSessa Capital

Funding

SEC filings, press & company announcements

$32.3M disclosed across 2 rounds · 2024–2026

▶$15.1MraisedJun 2026 · 13 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Philip BallExecutive Officer, Director
  • Damia Tormo CarullaDirector
  • Justin VogelExecutive Officer, Director
  • Francisco LeonExecutive Officer, Director
  • Pablo CironiDirector
  • Robert GoldsteinDirector
Amount sold
$15.1M
First sale
Jun 2026
Incorporated
Corporation, Delaware, 2023
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Related companies · 1

OsmosisOsmosis is a US health education platform of short-form medical videos and learning tools, acquired by Elsevier.

Companies working in the same space as Tolerance Bio.

In the news

Tolerance Bio, Inc. Launches with $17.2 Million in Seed Financing to Advance Thymus-Based Therapies for Immune-Mediated Diseases — Tolerance Bio | | Thymus-Powered Healthspan | Immune Tolerance | Control immune tolerance at will - by restoring, preserving, and manipulating the function of the thymustolerancebio.com · Oct 2024Tolerance Bio Raises $17.2M in Seed Financingfinsmes.com · Oct 2024

Frequently asked questions

What does Tolerance Bio do?
Tolerance Bio develops therapeutics targeting the thymus—the regulator of immune tolerance—to preserve, restore, and manipulate its function and extend health span. Its work includes iPSC-derived thymic organoids and licensed interleukin-7 therapy aimed at improving thymic function and immune resilience.
Who founded Tolerance Bio?
Tolerance Bio was founded by Francisco Leon in 2023.
Who are Tolerance Bio's investors?
Tolerance Bio's investors include BioAdvance, Criteria Bio Ventures, Ben Franklin Technology Partners, Columbus Venture Partners.
How much funding has Tolerance Bio raised?
Tolerance Bio has disclosed $32.3M raised across 2 rounds.
Where is Tolerance Bio headquartered?
Tolerance Bio is headquartered in Philadelphia, US.