Trestle Biotherapeutics
YC W21San Diego, US · Founded 2020 · 2 employees · 3 known investors
Trestle Biotherapeutics develops bioengineered implantable tissues designed to treat end-stage renal disease, aiming to get patients off dialysis and eventually provide replacement organs. The company uses stem cell biology, biofabrication, and 3D bioprinting technologies to create functional kidney tissue for patients with kidney failure.
Founders & leadership· Y Combinator alumni (W21)
Trestle Biotherapeutics was founded in 2020 by Ben Shepherd, Alice Chen, and Alice Chen, PhD.
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Ben ShepherdinCo-founder & CEOBen Shepherd is a vascular biologist and tissue engineer who previously held an academic position at Yale School of Medicine before spending over a decade in industry developing research teams focused on 3D bioprinting and biofabrication technologies for tissue engineering applications.
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Alice CheninCo-Founder & CSOAlice Chen has 20+ years of research experience in developmental biology, stem cell biology, and tissue engineering. She founded Trestle Biotherapeutics to develop therapeutic tissue for chronic kidney disease treatment.
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Alice Chen, PhD
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Ben Shepherd, PhDCEO
Investors · 3
Competitors · 3
by search overlapFortis Life Sciences8 shared keywordsFortis Life Sciences develops and manufactures Bethyl-branded ELISA kits and related reagents, buffers, and antibodies for detecting target proteins in research and diagnostic applications. The kits cover human and veterinary targets and are made in the USA using the company's own antibodies.
Krystalbio8 shared keywordsKrystal Biotech discovers, develops, and commercializes genetic medicines, including gene therapy programs for rare diseases such as dermatological conditions. The company operates across the US, Europe, and Japan.
Solu7 shared keywordsSolu Therapeutics is a clinical-stage biotech developing a class of antibody therapeutics that link bifunctional small molecules to proprietary effector antibodies (its CyTAC and TicTAC platforms) to reach cell surface targets like GPCRs and ion channels. Its pipeline targets oncology, immunology and inflammation, and pain, with a lead program in Phase 1 trials for chronic myelomonocytic leukemia.
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Frequently asked questions
- What does Trestle Biotherapeutics do?
- Trestle Biotherapeutics develops bioengineered implantable tissues designed to treat end-stage renal disease, aiming to get patients off dialysis and eventually provide replacement organs. The company uses stem cell biology, biofabrication, and 3D bioprinting technologies to create functional kidney tissue for patients with kidney failure.
- Who founded Trestle Biotherapeutics?
- Trestle Biotherapeutics was founded by Ben Shepherd, Alice Chen, Alice Chen, PhD in 2020.
- Who are Trestle Biotherapeutics's investors?
- Trestle Biotherapeutics's investors include Y Combinator, Draper Associates, Axial VC.
- Where is Trestle Biotherapeutics headquartered?
- Trestle Biotherapeutics is headquartered in San Diego, US.





