Hypothesis

Helping every company become a data company

Amplify offers a platform for data businesses to run personalized data sales, deliver datasets through options like Snowflake Share, APIs, and SFTP, and track customer data usage.

Data & InfrastructureEnterprise SoftwareSaaS

Array Behavioral Care provides virtual psychiatry and therapy across acute, outpatient, and at-home settings, using a clinical platform built on Epic to connect care across hospitals, clinics, and homes.

Digital HealthHealthtechMental Health

Online mental health support (Pre-Hypothesis Investment)

Building the AI-native benefits administrator

Avant Health is an AI-native third party benefits administrator that offers customized health plans and personalized benefits administration.

AI & Machine LearningHealthtechInsurTech

Billie is a direct-to-consumer body brand offering shaving products, including its award-winning razor, and bodycare essentials such as body wash, lotion, and deodorant.

ConsumerDirect to ConsumerE-commerce

Georgina Gooley(Founder)inJason Bravman(Founder)in

Brooklyn Health develops Willis, an electronic clinical outcome assessment (eCOA) solution aimed at measurement challenges in health and clinical research.

Digital HealthHealthtechSaaS

Standardizing the digital measurement of health

Brand Networks (BN) is a creator and employee advocacy platform that helps enterprise brands turn employees, customers, fans, and partners into creators of brand-safe original content and then amplify top-performing posts through paid media using AI-driven ad buying.

AI & Machine LearningMarketing TechSaaSRochester, US

Powering the entire private debt ecosystem

Cascade offers a platform for asset-based and private credit that provides independently verified data, automated debt operations, and facility monitoring for fintech lenders and institutional investors.

Data & InfrastructureFintechSaaS

Clora operates an AI-powered talent marketplace connecting biotech and pharma teams with 15,000+ vetted life sciences consultants across 300+ skillsets for fractional, on-demand engagements.

B2B MarketplacesBiotechFuture of WorkHR TechCambridge, US

Rahul Chaturvedi(Founder and CEO)

BoardJohn Melas-Kyriazi(Director)

Cove is a mobile app that gamifies personal saving and investing, letting users grow an island by stashing cash and building a portfolio, with FDIC-insured cash sweep and SIPC-insured brokerage services provided through partner Alpaca Securities.

ConsumerFintechGaming

David Wolfenden(Cofounder & CEO)inLiam Howell(Cofounder & CTO)inSarah Mirsky-Terranova(CCO)in

CoverRight helps Medicare-eligible seniors in the U.S. find, compare and enroll in health insurance plans, combining online technology with licensed advisors to provide personalized plan recommendations.

Digital HealthHealthtechInsurTechBrooklyn, US

Richard Chan(Executive Officer, Director)

BoardDean Dorrell(Director)in

Advanced trading platform for commercial real estate (Pre-Hypothesis Investment)

Dalinea provides SKU-level cost intelligence for supply chain management, offering detailed insights into materials, labor, energy, tariffs, and market inputs to help enterprises negotiate with suppliers and manage cost volatility.

Data & InfrastructureEnterprise SoftwareSaaS

Somerville, US

Alexander Bratianu(Founder)in

Transforming Mexico's financial sector

Digitt offers online personal loans that consolidate and pay off consumers' credit card debt at lower interest rates, with customizable repayment terms and digital applications.

ConsumerFintech

IQ.wiki (formerly Everipedia) is a crypto knowledge base offering wiki articles on blockchain, DeFi, and Web3 topics, projects, and people, fact-checked and updated by an AI editor called SOPHIA with entries signed on-chain via Polygon.

AI & Machine LearningCrypto & Web3Media & Entertainment

Flourish Health provides psychiatrist-led mental health care for young people ages 8-26 with serious conditions such as bipolar, depressive, anxiety, and trauma-related disorders.

Digital HealthHealthtechMental Health

Mental health care for teens and young adults

Front is a support and sales platform that combines messaging, internal collaboration, and AI automation to handle customer requests and sales workflows.

AI & Machine LearningEnterprise SoftwareFuture of WorkSaaSSales TechSan Francisco, US

Mathilde Collin(Founder/CEO)inLaurent Perrin(Founder/CTO)in

Building the front door to cheaper healthcare

Gift Health operates a digital pharmacy and prescription-access platform that handles patient enrollment, electronic benefits investigation, e-prior authorization, and nationwide prescription fulfillment.

Digital HealthHealthtechSaaS

Amobee, now known as Nexxen, is an advertising technology platform.

AdTech

Hologram provides global IoT connectivity solutions that simplify device management and reduce costs for businesses deploying internet-connected devices across multiple countries.

HardwareIoTSaaSChicago, US

Benjamin Forgan(Executive Officer, Director)Patrick Wilbur(Executive Officer, Director)Anne Rosen(Executive Officer)

BoardNick Solaro(Director)in

Jo is a personal AI agent that reads email, calendar, and connected apps to deliver a daily brief with actionable summaries, meeting prep, draft replies, and gentle reminders for work and personal life.

AI & Machine LearningConsumerFuture of WorkSaaSSan Francisco, US

Pradeep Elankumaran(Founder)inKevin Li(Founder)in

Keebler Health, founded in 2023, is a healthcare company focused on improving efficiency and efficacy in the healthcare industry.

AI & Machine LearningDigital HealthHealthtech

Isaac Park(CEO)Andrew Stickney(COO)Kevin Hill(CTO)Terrell Bacchus(CMO)

Future forward Asian food platform

Leda provides self-administered DNA testing kits and related services for individuals who have experienced sexual assault, aiming to improve evidence collection and support for survivors.

HealthtechImpact & Social GoodBrooklyn, US

Liesel Vaidya(Executive Officer, Director)Madison Campbell(Executive Officer, Director)

Supporting sexual assault survivors

Milu Health uses data and AI to improve healthcare outcomes and affordability by identifying health issues early and connecting patients with appropriate care.

AI & Machine LearningDigital HealthEnterprise SoftwareHealthtech

Gautam Kumar(Founder)in

Data integration platform for digital healthcare

Morf is an automation platform for healthcare practices that uses AI to simplify operations and eliminate manual tasks.

AI & Machine LearningHealthtechSaaS

Montana Scher(Founder)inJames Thompson(Founder)in

Oyster Technologies builds Cara, an AI-based "Agency Intelligence System" for insurance agencies, brokerages, and wholesalers.

AI & Machine LearningInsurTechSaaS

Simplified energy storage systems

PositivEnergy develops, owns, operates and maintains EV charging infrastructure for municipalities, airports, utilities, retailers and enterprises.

CleantechEnergy

Radish provides dedicated primary care teams led by physicians to help patients navigate healthcare and manage insurance coverage.

Digital HealthHealthtechHR TechWellness & FitnessNew York City, US

Viral Patel(Founder)in

Transforming data into engagement and revenue (Constant Contact)

Retention Science offers an AI-driven email marketing automation platform that personalizes messages across the customer lifecycle and unifies customer data for segmentation and targeting.

AI & Machine LearningE-commerceMarketing Tech

Salesbricks is a B2B revenue platform that combines CPQ, contracts and e-signature, checkout, order management, billing, and payments to take closed deals through to collected cash.

FintechSaaSSales Tech

Citrix provides a persona-based platform for secure application access, virtual desktops, and workspace delivery, letting organizations centrally manage apps and data across devices with zero trust access.

Cloud ComputingCybersecurityEnterprise Software

Social media optimization platform (BrandNetworks)

Chicago, US

Alex Segura(Executive Officer, Director)

BoardNick Moran(Director)inLaura Spiekerman(Director)

A network of web, search, and social media properties (IPO)

Starfish Space develops Otter, an autonomous satellite servicing vehicle that uses electric propulsion to dock with satellites for life extension and disposal.

Deep TechHardwareSpace TechTukwila, US

Trevor Bennett(Co-founder)Austin Link(Co-founder)

BoardMorgan Beller(Director)inPeter Ortez(Director)Letitia Long(Director)

SonarMD provides a care management platform for chronic diseases, starting with gastroenterology, that combines AI technology with human support to detect clinical deterioration early and help specialists intervene before emergencies.

AI & Machine LearningDigital HealthHealthtechMedical DevicesSaaSChicago, US

LAWRENCE R KOSINSKI(Director)Lawrence R. Kosinski(Founder and Board Member)BETH HOUCK(Executive Officer, Director)inJohn Starr(Executive Officer)Devin Gross(Executive Officer, Director)

BoardTHOMAS M SHEHAB(Director)