A-Alpha Bio
Seattle, US · Founded 2017 · Delaware corporation · 49 employees on LinkedIn · 8 known investors
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A-Alpha Bio uses synthetic biology and machine learning to measure, predict, and engineer protein-protein interactions for pharmaceutical discovery and development. The company operates experimental (AlphaSeq) and computational (AlphaBind) platforms to accelerate the design of novel therapeutics.
Founders & leadership
A-Alpha Bio was founded in 2017 by David Younger, PhD, Randolph Lopez, PhD, David Younger, and Randolph Lopez.



Investors · 8
How we know: Breakout Ventures's portfolio page · a partner's Signal profile · the VCSheet dataset · open dataset · 5k.vc investor directory · Not right? Tell us
How we know: Farvatn Venture's portfolio page · Not right? Tell us
How we know: Lux Capital's portfolio page · a partner's Signal profile · funding news · Not right? Tell us
How we know: Madrona Venture Group's portfolio page · the VCSheet dataset · Not right? Tell us
How we know: the VCSheet dataset · Not right? Tell us
How we know: the VCSheet dataset · Not right? Tell us
Funding
SEC filings, press & company announcements$23.1M disclosed across 2 of 4 rounds · 2019–2023
- Undisclosed amountSeries A2Jul 2023Source ↗
▶$20.3MraisedSep 2021 · 18 investors · Other TechnologyRule 506(b)
- Ben AskewDirector
- Randolph Lopez BarrezuetaDirector
- Matt McIlwainDirector
- David YoungerExecutive Officer, Director
- Offering amount
- $20.3M
- Amount sold
- $20.3M
- First sale
- Aug 2021
- Incorporated
- Corporation, Delaware, 2017
- Federal exemptions
- 06b
▶$2.8MraisedSep 2019 · 15 investors · Other TechnologyRule 506(b)
- David YoungerExecutive Officer, Director, Promoter
- Offering amount
- $2.8M
- Amount sold
- $2.8M
- First sale
- Sep 2019
- Incorporated
- Corporation, Delaware, 2017
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Related companies · 2
Companies working in the same space as A-Alpha Bio.
Non-dilutive funding · 3 SBIR/STTR awards
Federal grants — no equity taken| Agency | Phase | Year | Amount |
|---|---|---|---|
| National Science Foundation | Phase II | 2020 | $620.5K |
| National Science Foundation | Phase I | 2020 | $256K |
| National Science Foundation | Phase I | 2018 | $225K |
Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.
In the news
Frequently asked questions
- What does A-Alpha Bio do?
- A-Alpha Bio uses synthetic biology and machine learning to measure, predict, and engineer protein-protein interactions for pharmaceutical discovery and development. The company operates experimental (AlphaSeq) and computational (AlphaBind) platforms to accelerate the design of novel therapeutics.
- Who founded A-Alpha Bio?
- A-Alpha Bio was founded by David Younger, PhD, Randolph Lopez, PhD, David Younger, Randolph Lopez in 2017.
- Who are A-Alpha Bio's investors?
- A-Alpha Bio's investors include Angel Collective Opportunity Fund, Breakout Ventures, Farvatn Venture, Lux Capital, Madrona Venture Group, Boom Capital, Boom Capital Ventures, OS Fund.
- How much funding has A-Alpha Bio raised?
- A-Alpha Bio has disclosed $23.1M raised across 2 of its 4 known rounds.
- Where is A-Alpha Bio headquartered?
- A-Alpha Bio is headquartered in Seattle, US.







