/Companies

A-Alpha Bio

Seattle, US · Founded 2017 · Delaware corporation · 49 employees on LinkedIn · 9 known investors

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A-Alpha Bio uses synthetic biology and machine learning to measure, predict, and engineer protein-protein interactions for pharmaceutical discovery and development. The company operates experimental (AlphaSeq) and computational (AlphaBind) platforms to accelerate the design of novel therapeutics.

Founders & leadership

A-Alpha Bio was founded in 2017 by David Younger, PhD, Randolph Lopez, PhD, David Younger, and Randolph Lopez.

DYDavid Younger, PhD
David Younger, PhDChief Executive Officer & Co-Founder
RL
Randolph Lopez, PhDChief Technology Officer & Co-Founder
DYDavid Younger
David YoungerCo-Founder and CEODavid Younger is Co-Founder and CEO of A-Alpha Bio, a Seattle-based synthetic biology company that applies machine learning to protein-protein interaction engineering for drug discovery. He holds a PhD in Bioengineering from the University of Washington and has expertise in synthetic biology and protein engineering.
RLRandolph Lopez
Randolph LopezCo-founder & CTOFounder of A-Alpha Bio, which uses synthetic biology and machine learning to engineer protein-protein interactions for drug discovery. Lopez has experience at the intersection of biology, technology, and startup development.

Investors · 9

Funding

SEC filings, press & company announcements

$23.1M disclosed across 2 of 4 rounds · 2019–2023

▶$20.3MraisedSep 2021 · 18 investors · Other Technology
Rule 506(b)
Officers, directors & promoters on the filing
  • Ben AskewDirector
  • Randolph Lopez BarrezuetaDirector
  • Matt McIlwainDirector
  • David YoungerExecutive Officer, Director
Offering amount
$20.3M
Amount sold
$20.3M
First sale
Aug 2021
Incorporated
Corporation, Delaware, 2017
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$2.8MraisedSep 2019 · 15 investors · Other Technology
Rule 506(b)
Officers, directors & promoters on the filing
  • David YoungerExecutive Officer, Director, Promoter
Offering amount
$2.8M
Amount sold
$2.8M
First sale
Sep 2019
Incorporated
Corporation, Delaware, 2017
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Related companies · 2

Companies working in the same space as A-Alpha Bio.

Non-dilutive funding · 3 SBIR/STTR awards

Federal grants — no equity taken
AgencyPhaseYearAmount
National Science FoundationPhase II2020$620.5K
National Science FoundationPhase I2020$256K
National Science FoundationPhase I2018$225K

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.

In the news

Frequently asked questions

What does A-Alpha Bio do?
A-Alpha Bio uses synthetic biology and machine learning to measure, predict, and engineer protein-protein interactions for pharmaceutical discovery and development. The company operates experimental (AlphaSeq) and computational (AlphaBind) platforms to accelerate the design of novel therapeutics.
Who founded A-Alpha Bio?
A-Alpha Bio was founded by David Younger, PhD, Randolph Lopez, PhD, David Younger, Randolph Lopez in 2017.
Who are A-Alpha Bio's investors?
A-Alpha Bio's investors include Angel Collective Opportunity Fund, Breakout Ventures, Farvatn Venture, Lux Capital, Madrona Venture Group, Planet 9 Capital, Boom Capital, Boom Capital Ventures and 1 more.
How much funding has A-Alpha Bio raised?
A-Alpha Bio has disclosed $23.1M raised across 2 of its 4 known rounds.
Where is A-Alpha Bio headquartered?
A-Alpha Bio is headquartered in Seattle, US.