/Companies

Arzeda

Seattle, US · Founded 2009 · Delaware corporation · 78 employees on LinkedIn · 14 known investors

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Arzeda designs proteins and metabolic pathways using computational tools, including its Archytas protein design software and Scylax metabolic pathway design software. The company operates in the computational biology and protein engineering field.

Founders & leadership

Arzeda was founded in 2009 by Alexandre Zanghellini, Eric Althoff, and David Baker.

AZAlexandre Zanghellini
Alexandre ZanghelliniCo-founder & CEOAlexandre Zanghellini holds a Ph.D. in biochemistry from the University of Washington and a master's degree in computer engineering from ENSTA ParisTech, with prior research and development experience in both academic and industrial settings. He is co-founder and CEO of Arzeda, where he leads product, technology, and corporate strategy for the company's computational biology and protein engineering platform.
EAEric Althoff
Eric AlthoffFounder and CTO-Chemistry2009–2013Eric Althoff is a business development professional with over 10 years of experience in biotechnology and pharmaceutical product development, having sourced and negotiated multiple collaboration agreements and led capital raising efforts as co-founder of Arzeda.
DBDavid Baker
David BakerCo-founder and Scientific Advisor
BBBill Baum
Bill BaumNamed on SEC filing
AB
Andrew BanNamed on SEC filing
DG
Daniela GrabsNamed on SEC filing

Board

JKJeff Klunzinger
Jeff KlunzingerBoard MemberCo-Founder and General Partner at OS Fund

Investors · 14

Also in the syndicate · 5

Bioeconomy CapitalBunge VenturesSilver BlueSucden VenturesW.L. Gore & Associates

Funding

SEC filings, press & company announcements

$120.9M disclosed across 7 of 8 rounds · 2017–2025

▶$4.5MraisedSep 2025 · 6 investors · Other
Rule 506(b)
Officers, directors & promoters on the filing
  • Larry PageDirector
  • Yanniv DoroneDirector
  • William BaumDirector
  • Doug CameronDirector
  • Sanjay PalExecutive Officer
  • Alexandre ZanghelliniExecutive Officer, Director, Promoter
  • Brian LoebDirector
  • Daniela GrabsDirector
Offering amount
$25M
Amount sold
$4.5M
First sale
Aug 2025
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$37.9MraisedAug 2024 · 21 investors · Other
Rule 506(b)
Officers, directors & promoters on the filing
  • Daniela GrabsExecutive Officer, Director
  • Yanniv DoroneDirector
  • Brian LoebDirector
  • Larry PageDirector
  • William BaumDirector
  • Sanjay PalExecutive Officer
  • Doug CameronDirector
  • Alexandre ZanghelliniExecutive Officer, Director, Promoter
Offering amount
$38M
Amount sold
$37.9M
First sale
Oct 2023
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$25.7MraisedJul 2021 · 14 investors · Other
Rule 506(b)
Officers, directors & promoters on the filing
  • Brian LoebDirector
  • Doug CameronDirector
  • William BaumDirector
  • Alexandre ZanghelliniExecutive Officer, Director, Promoter
  • Daniela GrabsExecutive Officer, Director
  • Jeffrey KlunzingerDirector
Offering amount
$38.8M
Amount sold
$25.7M
First sale
Jul 2021
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$3.3MraisedNov 2020 · 3 investors · Other
Rule 506(b)
Officers, directors & promoters on the filing
  • Alexandre ZanghelliniExecutive Officer, Director, Promoter
  • Jeff KlunzingerDirector
  • Daniela GrabsExecutive Officer, Director
  • Bill BaumDirector
  • Doug CameronDirector
Offering amount
$5M
Amount sold
$3.3M
First sale
Oct 2020
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$1MraisedNov 2019 · 1 investors · Other
Rule 506(b)
Officers, directors & promoters on the filing
  • Alexandre ZanghelliniExecutive Officer, Director, Promoter
  • Eric AlthoffExecutive Officer, Director, Promoter
  • Jeff KlunzingerDirector
  • Bill BaumDirector
  • Andrew BanExecutive Officer
  • Daniela GrabsExecutive Officer
Offering amount
$3M
Amount sold
$1M
First sale
Nov 2019
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$10.5MraisedJul 2017 · 5 investors · Other
Rule 506(b)
Officers, directors & promoters on the filing
  • Jeff KlunzingerDirector
  • Daniela GrabsExecutive Officer, Promoter
  • Alexandre ZanghelliniExecutive Officer, Director, Promoter
  • Bill BaumDirector
  • Eric AlthoffExecutive Officer, Director, Promoter
Offering amount
$12.2M
Amount sold
$10.5M
First sale
Jul 2017
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Founder mafia

3 people who came through Arzeda went on to found or lead other companies.

Related companies · 1

Companies working in the same space as Arzeda.

Non-dilutive funding · 9 SBIR/STTR awards

Federal grants — no equity taken
AgencyPhaseYearAmount
Department of DefenseOffice for Chemical and Biological DefensePhase II2022$1.1M
National Science FoundationPhase II2015$744.8K
Department of EnergyPhase I2015$224.9K
National Science FoundationPhase II2013$500K
National Science FoundationPhase ISTTR2013$225K
National Science FoundationPhase I2011$150K
National Science FoundationPhase I2011$149.9K
National Science FoundationPhase I2010$149.2K
Department of Agriculture (USDA)Phase I2010$90K

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.

In the news

Frequently asked questions

What does Arzeda do?
Arzeda designs proteins and metabolic pathways using computational tools, including its Archytas protein design software and Scylax metabolic pathway design software. The company operates in the computational biology and protein engineering field.
Who founded Arzeda?
Arzeda was founded by Alexandre Zanghellini, Eric Althoff, David Baker in 2009.
Who are Arzeda's investors?
Arzeda's investors include Circulate Capital, Fall Line Capital, Sofinnova Partners, Sustainable Conversion Ventures, Continental Grain Company, Lewis & Clark AgriFood, OS Fund, Universal Materials Incubator and 1 more.
How much funding has Arzeda raised?
Arzeda has disclosed $120.9M raised across 7 of its 8 known rounds.
Where is Arzeda headquartered?
Arzeda is headquartered in Seattle, US.